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Blood
Blood is:
55% Plasma
45% Cells
What is plasma?
Plasma is the
liquid portion
of blood
Plasma is:
91.5% water. Transport
medium.
7% proteins, e.g., clotting
factors, antibodies
1.5% other solutes, e.g., hormones,vitamins, amino
acids, glucose, fatty acids, nitrogen wastes,
electrolytes (Ca++, Na+, K+, H+)
What kinds of
cells do we find
in the blood?
Red Blood Cells (RBCs) =
Erythrocytes
• >99% of total blood cells are RBCs
• ~5 million/ml
• Hb
• Fe
• Transport O2 and CO2
• No nucleus when mature
Platelets = Thrombocytes
• Involved in blood clotting
• 150,000 – 400,000/ml
White Blood Cells (WBCs) = Leukocytes
Defense system
5,000 – 10,000/ml
There are 5 different types of WBCs
Neutrophils = PMNs = Polymorphonucleocytes
or Poly’s
• Most abundant of
the WBCs
• Phagocytic
• Kill bacteria
Basophils
• Release histamine.
• Their numbers increase
in allergic reactions
Eosinophils
• Fight parasitic infections
• Some allergic reactions,
esp. asthma, are the
result of the malfunctioning of eosinophils.
Lymphocytes
• Produce
antibodies
• Fight viruses
What % of blood is plasma?
A.) 65
B.) 45
C.) 55
D.) 90
Monocytes
• Size-wise, is largest
of the WBCs
• Phagocytic
• Large kidney-shaped
nucleus
The blood cell that releases histamine
in an allergic reaction is
A.) neutrophil
B.) basophil
C.) esinophil
D.) lymphycyte
Important Hematology Lab Terms
1. CBC = Complete Blood Count
Normal (nl) values:
RBCs: 4.2-5.9 million/ml
WBCs: 5,000-10,000/ml
Platelets: 100,000 – 400,000/ml
CBC c diff (differential)
Nl values:
PMNs: 60-70%
Lymphos: 20-25%
Monos: 3-8%
Eos: 2-4%
Basos: 0.5-1%
Hematocrit (or ‘crit, if you want to sound cool)
The percent of whole blood made up of red
blood cells.
Nl value: 40-50%
Let’s run a virtual
hematocrit
http://scienceu.fsu.edu/content/virtuallab/hematology/docs/hematocrit.html
Hemoglobin – Hb
Do you remember what hemoglobin
is?
A nl hemoglobin value is 12-16g/dl
WBC that fight viruses are
A.) Esinophils
B.) Lymphocytes
C.) Basophils
The most abundant kind of
Leukocytes are
A.) Netrophils
B.) Basophils
C.) Monophils
D.) Esinophils
How many kinds of leukocytes are
there
A.) 4
B.) 5
C.) 2
D.) 3
The largest WBC is
A.) Neutophils
B.) Basophils
C.) Monocytes
D.) Esinophils
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