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The Urinary System OVERVIEW https://www.youtube.com/watch?v=lfGYd1 wrTgE&list=PLR6xLyq3PY7GVj1h5mFQ9Y9mMj_jnmWQ Bozeman https://www.youtube.com/watch?v=qfWx8 msgHqM Function 1. Remove nitrogenous wastes 2. Maintain electrolyte(ions), pH (acid-base), and fluid balance of What does this mean? blood It regulates the water and salt in the body. So… 3. Homeostatic organ whatever excess we have, 4. Acts asusblood it helps get rid offilter it. 5. Release hormones Kidneys as Filters • Average kidney filtration rate = 180 liters (50 gal) of blood/day • 178-179 liters are reabsorbed back into blood Nitrogenous Wastes urea uric acid ammonia kidneys Organs of the Urinary System ureters urinary bladder urethra Check your kidney diagram Calyx Renal column Medullary pyramid Pelvis Fibrous capsule Renal cortex Kidney Anatomy renal pelvis ureter renal pyramids renal cortex renal capsule renal medulla http://www.youtube.com/watch?v=cc8sUv 2SuaY&feature=related Nephron = nephron functional unit of kidney Each kidney contains > 1,000,000 nephrons. renal artery renal vein Kidney Anatomy blood Nephron Functioning filtration tubular reabsorption and secretion urine “refreshed” blood efferent arteriole afferent arteriole glomerulus artery peritubular capillaries loop of Henle vein Bowman’s capsule proximal convoluted tubule distal convoluted tubule collecting duct Glomerulus DCT Each kidney contains over 1 million nephrons and thousands of collecting ducts PCT Collecting duct Loop of Henle renal cortex renal medulla efferent arteriole afferent arteriole Glomerular Filtration Bowman’s capsule glomerulus Filters blood; proteins can’t pass through Add ARROWS TO Figure 15-3: Diagram of a NEPHRON. Label NEPHRON diagram 1. 2. 3. 4. 5. 6. 7. 8. 9. Glomerular capsule Afferent arteriole Efferent arteriole Cortical radiate artery Cortical radiate vein Arucate artery Arcuate vein Interlobar artery Interlobar vein Loop of Henle (nephron loop) 11. Collecting duct 12. Distal convoluted tubule 13. Proximal convoluted tubule 14. Peritubular capillaries 15. glomerulus 10. Composition of Glomerular Filtrate (1,15) • Water • Small Soluble Organic Molecules (i.e. amino acids, glucose) • Mineral Ions Proximal Convoluted Tubule (13) Reabsorbs: water, glucose, amino acids, and sodium. Loop of Henle (10) Descending – reabsorbs H2O Ascending – reabsorbs Na+ and Cl- Distal Convoluted Tubule (12) ABSORBS - H20 Ca++ PO4 (phosphates) Na+ SECRETES - H+ K+ Collecting Duct (11) Allows for the osmotic reabsorption of water. Urine Water- 95% Nitrogenous waste: • urea • uric acid • Creatinine (waste product of muscle cell metabolism) Ions: • sodium • potassium • sulfate • phosphate Urinary Bladder ureters external sphincters internal sphincters Draw & label urethra Sphincter Muscles on Bladder Internal urethral sphincter: • Smooth muscle • Involuntary control External Urethral sphincter: • Skeletal muscle • Voluntary control Diuresis When bladder fills with 200 ml of urine, stretch receptors transmit impulses to the CNS and produce a reflex contraction of the bladder (PNS) Micturition – Distension of the Urinary Bladder voiding; eliminating urine Urinalysis Why do doctors ask for a urine sample? characteristics: • smell- ammonia-like • pH- 4.5-8, ave 6.0 • specific gravity– more than 1.0; ~1.0011.003 • color- affected by what we eat: salty foods, vitamins Odor odor- normal is ammonia-like diabetes mellitus- smells fruity or acetone like due to elevated ketone levels diabetes insupidus- yucky asparagus--- pH- range 4.5-8 ave 6.0 vegetarian diet- urine is alkaline protein rich and wheat diet urine is acidic Color Color- pigment is urochrome Yellow color due to metabolic breakdown of hemoglobin (by bile or bile pigments) Beets or rhubarb- might give urine a pink or smoky color Vitamins- vitamin C- bright yellow Infection- cloudy Abnormal Contents of Urine Glucose- when present in urine condition called glycosuria (nonpathological) [glucose not normally found in urine] Indicative of: • Excessive carbohydrate intake • Stress • Diabetes mellitus