Download Aromatic compounds (McM chapt. 16, 17)

KJM3200 - Organic Chemistry II
Form of teaching
Laboratory course (120 hours) Lectures (20 hours). Colloquiums (10 hours.)
Form of exam
Written exam (3 hours) Monday June 13.
Recommended prerequisites
KJ120 or KJ101 or KJM1010+1020
http://www.uio.no/studier/emner/matnat/kjemi/KJM3200/v05/
Lecture plan
Alkene related chemistry (McM chapt. 6, 7, 8, 10, 11, 14, 18,)
Aromatic compounds (McM chapt. 16, 17)
Carbonyl compounds (McM chapt. 19, 21, 22, 23)
Amines (McM chapt. 24)
Karbohydrates (McM chapt. 25)
Amino acids etc. (McM chapt. 26)
Lipids (McM chapt. 27)
Heterocycles etc (McM chapt 28)
Pericyclic Reactions (McM chapt 30)
Alkenes
C
Double bond: p and s
C
C
C
Electrophilic addition to alkenes
A-B
C
C
Alkene
A
C
C
B
Funktionalized "alkane"
ex. AB = HX, XX: Alkyl halides
sp2 C
120 o
H
H
+ HBr
Br
Br
TS#1
Energy
TS#2
H
Br
G#2
Intermediate(s)
G#1
+ HBr
Go
Reactant(s)
H
Br
Product(s)
React. prog.
The Hammond Postulate
The structure of the TS# resembles the structure of the nearest (in energy) stable species
Product like TS#
Reactant like TS#
TS#
TS#
Reactant
Prod
G>0
G>0
Prod
Reactant
Exergonic step
Endergonic step