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Transcript 
Metabolism in
Nervous Tissue
•Glycolysis
•Glycogenolysis (stress)
-oxidation (ketone bodies)
•Krebs (tricarboxylic acid) cycle
•Branched-chain amino acids
•Electron transport chain
Eric Niederhoffer
SIU-SOM
Pathways Overview
Glucose
Glycogen
Glycolysis
Glycogenolysis
Lactate
(glial)
Lactate
G6P
No O2
Pyruvate
BCAA
Ile, Leu, Val
Krebs
cycle
Ketone
bodies
Fatty
acids
-oxidation
Acetyl-CoA
Electron
Transport
Chain
Production of ATP
Review Questions


How does nervous tissue (neurons and
glial cells) produce ATP (carbohydrates,
fatty acids, ketone bodies, branchedchain amino acids)?
How do glial cells (astrocytes) assist
neurons?
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