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Transcript 
b Structures
Up-and-down b barrel
Source: Introduction to Protein Structure by Branden & Tooze
Superoxide dismutase
Source: Introduction to Protein Structure by Branden & Tooze
Up-and-down b barrel
Source: Introduction to Protein Structure by Branden & Tooze
Plasma retinol-binding protein (RBP)
Source: Introduction to Protein Structure by Branden & Tooze
Binding site for retinol inside RBP barrel
Source: Introduction to Protein Structure by Branden & Tooze
Amino acid sequence of b strands 2 3 4 in RBP
Source: Introduction to Protein Structure by Branden & Tooze
Neuraminidase from influenza virus
Source: Introduction to Protein Structure by Branden & Tooze
Subunit structure of neuraminidase
headpiece (84-469)
Source: Introduction to Protein Structure by Branden & Tooze
Tetrameric Neuraminidase
Source: Introduction to Protein Structure by Branden & Tooze
Neuraminidase-active site
Source: Introduction to Protein Structure by Branden & Tooze
Greek key motif
Source: Introduction to Protein Structure by Branden & Tooze
Greek key motif-two possibilities
Source: Introduction to Protein Structure by Branden & Tooze
g-crystallin
Source: Introduction to Protein Structure by Branden & Tooze
g-crystallin
Source: Introduction to Protein Structure by Branden & Tooze
g-crystallin
Source: Introduction to Protein Structure by Branden & Tooze
g-crystallin
Source: Introduction to Protein Structure by Branden & Tooze
g-crystallin
Source: Introduction to Protein Structure by Branden & Tooze
Jelly roll barrel
(Swiss roll)
Source: Introduction to Protein Structure by Branden & Tooze
Source: Introduction to Protein Structure by Branden & Tooze
Source: Introduction to Protein Structure by Branden & Tooze
Source: Introduction to Protein Structure by Branden & Tooze
Single subunit of influenza virus hemagglutinin
Source: Introduction to Protein Structure by Branden & Tooze
Hemagglutinin
Source: Introduction to Protein Structure by Branden & Tooze
Trimers of Hemagglutinin
Source: Introduction to Protein Structure by Branden & Tooze
Sialic acid
Source: Introduction to Protein Structure by Branden & Tooze
Distorted jerry roll structure
of hemagglutinin globular head
Source: Introduction to Protein Structure by Branden & Tooze
Inhibitor-hemagglutinin
Source: Introduction to Protein Structure by Branden & Tooze
Hemagglutinin at low pH
Source: Introduction to Protein Structure by Branden & Tooze
Conformational change between high & low pH forms of
hemagglutinin
Source: Introduction to Protein Structure by Branden & Tooze
Where is fusion peptide ?
Source: Introduction to Protein Structure by Branden & Tooze
Source: Introduction to Protein Structure by Branden & Tooze
Tamm Laboratory at
http://faculty.virginia.edu/tamm/pag
es/project_fusion.html
Source: Introduction to Protein Structure by Branden & Tooze
Cell Vol 89, p263 (1997) Chan et al.
Core Structure of gp41 from the
HIV Envelope Glycoprotein
The envelope glycoprotein of human
immunodeficiency virus type 1 (HIV-1) consists of a
complex of gp120 and gp41. gp120 determines
viral tropism by binding to target-cell receptors,
while gp41 mediates fusion between viral and
cellular membranes.
Source: Introduction to Protein Structure by Branden & Tooze
Source: Introduction to Protein Structure by Branden & Tooze
Source: Introduction to Protein Structure by Branden & Tooze
Source: Introduction to Protein Structure by Branden & Tooze
Source: Introduction to Protein Structure by Branden & Tooze
Parallel b-helix
Source: Introduction to Protein Structure by Branden & Tooze
Two sheet b-helix
Source: Introduction to Protein Structure by Branden & Tooze
Three sheet b-helix
Source: Introduction to Protein Structure by Branden & Tooze
Pectate lyase C
Source: Introduction to Protein Structure by Branden & Tooze
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