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Nucleic Acids
Nucleic Acids
• Sugar + phosphate + nitrogenous base
• CHONP
Nucleic Acids
• DNA
deoxyribonucleic • RNA
ribonucleic acid
acid
Nucleotides: 3 parts
• 5-C sugar
• Phosphate Group
• Nitrogenous Bases
A, T, C, G
Sing Along Songs - Row, Row,
Row Your Boat
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We love DNA
Made of nucleotides
Sugar, Phosphate, and a base
Bonded down one side
• Adenine with thymine make a lovely
pair
• Cytosine without guanine would feel
very bare.
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4 Nitrogenous Bases
in DNA
in RNA
A = adenine
T = thymine
C = cytosine
G = guanine
A = adenine
U =uracil (replaces T
in DNA)
C= cytosine
G = guanine
DNA Base Pairing
• A – T (adenine with thymine)
• C – G (cytosine with guanine)
DNA and RNA
-DNA is
double stranded
-Bases: A-T, C-G
-Only in nucleus
-Deoxyribose
sugar
-RNA is single
stranded
-Bases: A-U, C-G
-In nucleus and
in cytoplasm
-Ribose sugar
Nitrogenous Bases
Purines = two rings- AG (silver)
Pyrimidines = CUT -one ring
(pie)
Nitrogenous Base
• Why is it called a
base?
• Remember NH2 to
NH3 (picks up H+);
it’s a weak base
Nucleoside
Nitrogenous Base + Ribose Sugar (5-C)
Check your
Pattern Matching
pp. 9-10
Nucleosides
• Uses in medicine
as antiviral or
anticancer agents
Ribasphere-a
nucleoside
Nucleotide: ribose sugar +
phosphate+ nitrogenous base
Compare Nitrogenous Base
with Nucleoside
• Guanoside
• Guanine
(nitrogenous base
Nitrogenous Base
of guanine + ribose
sugar)
SNEAK PREVIEW
• DNA molecule
• Sections of it are genes
• Genes are the codes that
make specific amino acids that
link together to make a protein
Hydrogen Bonds
•Join nucleotides
together