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What is Cellular Respiration?
energy
• When organisms release the _________
stored in carbohydrates and other food
molecules
Glucose
Fructose
Sucrose: A disaccharide
Monosaccharides
3 stages of Cellular Respiration
1. Glycolysis:
•
•
Occurs in the cytoplasm
No O2 required
2. Krebs Cycle:
•
Occurs in the mitochondrion
3. Electron Transport Chain
•
Requires O2
Aerobic
Respiration
1. Occurs when Oxygen
is present
2. Many ATP Molecules
made
Anaerobic
Respiration
1. Occurs when no
Oxygen is present
2. Very little ATP made
3. Two basic types:
a. Fermentation:
Alcohol and CO2
produced
b. Lactic Acid
“Glyco” “lysis” literally means
“sugar” “splitting”
ATP
ADP
P
ATP
ATP
ADP
P
= -2
Glycolysis takes place in the
cytoplasm
+
P
NADH
NAD
P
P
NADH
NADP+
NADH = +2
Glycolysis takes place in the
cytoplasm
P
ATP
ADP
P
ATP
= +2
ATP
P
ADP
P
Glycolysis takes place in the
cytoplasm
ATP
ADP
P
ATP
ADP
P
ATP
= +2
Pyruvate
What is the
net gain of
energy in
Glycolysis?
• ATP = + 2
• NADH = + 2
What did Krebs and Chance
Discover in their Research?
• Enjoy this video clip, and jot down a
summary of Krebs’ and Chance’s
research.
• Pay attention to the significance of both
scientist’s discoveries.
Label the parts of the
mitochondrion
Inner membrane
Outer membrane
Cristae
Matrix
Intermembrane
space
The Krebs Cycle takes place in
the Matrix of the Mitochondrion
NADH
NAD+
CoA
Acetyl CoA
NADH
NAD+
CoA
The Krebs Cycle takes place in
the Matrix of the Mitochondrion
CoA
Citrate
The Krebs Cycle takes place in
the Mitochondrion
NADH
NAD+
The Krebs Cycle takes place in
the Mitochondrion
NADH
NAD+
The Krebs Cycle takes place in
the Mitochondrion
ATP
ADP
NADH
NAD+
P
The Krebs Cycle takes place in
the Mitochondrion
FADH
FADH2
What is gained and lost for each
pyruvate molecule?
• What is lost during
the Krebs Cycle?
– A Carbon atom must
be lost
– It is lost in the form of
Carbon Dioxide
– There are 3 CO2
molecules lost
• What is gained during
the Krebs Cycle?
– 4 NADH molecules are
made.
– 1 FADH2 molecule is
made
– 1 ATP molecule is
made
What is gained per glucose
molecule?
NADH = +8
+4
ATP = +1
+2
FADH2 = +2
+1
• But there were two
molecules of Acetyl
CoA (per glucose)
that went into the
Krebs Cycle…
• How many would
actually be produced
in this case?
Where is the energy?
• So far, most of the usable energy from the
original glucose molecule is stored as
NADH and FADH2
electrons in
• Where will most of the ATP be made?
The Electron Transport Chain
Where is the Electron Transport
Chain?
Inside the mitochondrion.
Many ATP molecules will
be produced in these
Folds of the inner membrane
Electron Transport Chains
known as cristae.
How much ATP can each
electron carrier make?
ATP
NADH
ATP
ATP
FADH2
FADH2
FADH2
ATP
ATP
After electrons travel through the ETC, Oxygen is the
final electron acceptor. Electrons, and two Hydrogen
ions attach to the oxygen, and H2O is formed.
Hydrogen ions pump from the matrix to the intermembrane space, using the energy from the
electrons.
The diffusion of H+ ions through the enzyme,
ATP synthase makes ATP
C6H12O6
ATP
C6H12O6
CO2
H2O
ATP
C6H12O6 + O2
CO2 + H2O +
ATP
Photosynthesis and
Respiration
• With a neighbor,
fill in the steps in
this cycle of
Photosynthesis
and Respiration.
• We will check
your answers
when you are
done!
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