Download Other Blood Groups

Other Blood Groups
Kidd
1. Chromosome 18
2. Transmembrane Protein
3.Different beeween Jk a,b
Jka280 Aspartic acid
Jkb280 Aspargin
4. Find in 11 week fetus
Kidd
• 1: allels
a
b
Jk / Jk
+
(a
+
b ),
+
(a
b ),
.2 : Rolling
Urea carrier
(a
+
b ),
(a
b )
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Duffy
• Seat on Carbohydrate
• Chromosome 1
• Near the gene of Anti
thrombin III & Type 1
hereditary motor and sensory
neuropathy
• Formation in 6-7 week fetus
a
• Fy
b
• Fy
• Fy3
• Fy5
6
• Fy
x
• Fy
Duffy
(a+
(a+
(a(a-
b+)
b-)
b+)
b-)
• Fyx is the weak type of
b
Fy
• Fy a,b denature with
Enzyme but not for Fy
3,5
• Duffy
recipient of CXC
(IL-8,MGSA) & CC (MCP-1)
Melanoma Growth Stimulatory Activity
Monocyte Chemotactic Peptide 1
• Fy a, b, 6
recipient of
P.vivax, P.knovlesi
I
• Chromosome 6
• N.Acetil Glucose Aminil Transferase
• I has 5 exons
1A, 1B, 1C, 2, 3
I
•I
in branching carbohydrate
in Adult
•i
in linear carbohydrate
in Child
• Anti I
Mlignancy
Mycoplasma,
• Anti i
Infectious
mononucleosis, Cirrhosis
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