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Homework 1 Part 2 Drug Resistance and Malaria Download “Drug Resistance and Malaria” by Peter Bloland, published by the World Health Organization: http://www.who.int/csr/resources/publications/drugresist/ malaria.pdf. “[T]here is a great disparity between the public health importance of the disease and the amount of resources invested in developing new cures.” Using this reference as your guide, answer the following questions. Drug Resistance and Malaria A) What three groups of people are most at-risk for developing severe or fatal malarial illness? B) Which region of the world is experiencing the most significant problem with drug resistant Plasmodium falciparum malaria? (Hint: see Table 3) Drug Resistance and Malaria C) What would be the yearly cost of treating every malaria infection on earth with the least expensive single-agent antimalarial? (Note: use the WHO’s low-end estimate of global incidence, and assume that one treatment per patient will cure the infection; see Table 2) D) Combination therapy reduces the emergence of drug resistance. What would be the yearly cost of treating every malaria infection on earth with the least expensive combination therapy (assuming every infection is chloroquine and SP resistant)? Drug Resistance and Malaria E) In one sentence each, describe three proposed strategies to prevent anti-malarial drug resistance.