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Basic principles of vascular
surgery
Anatomy
 Physiology
 Pathology
 Pathophysiology
Clinical presentation.History, physical
exam.
investigation
management

physiology


Haemostasis
vasoconstriction
platelet
aggregation
 Coagulation intrinsic, extrinsic
 Fibrinolysis
 Renin angiotensin system
Vascular pathology






Atherosclerosis:
formation,flow
placque
effect, fate of the
placque
Risk factors
Clinical sequelae : stenosis, occlusion,
thrombosis,
embolisation,
aneurysm
Vascular pathology
1-Trauma:RTA,falls, stabs, gun shot,
sharps
Iatrogenic
DRUG ADDICT
2-Inflammatory: (VASCULITIS)
Takayassaue, Kawasaki, Beurger
Connective tissue (SLE, polyart. Nod.,
Rh. Art.,)
3-Spasmodic Reynauds dis.,
phenomenon
4-Conginetal malformation : venous,
arterial
AVM
symptomatology
Chief complaint, history of the
present illness



Peripheral vascular symptoms
atherosclerosis risk factors
Review of important systems
Peripheral vascular
symptoms
Acute ischaemia
 Chronic ischaemia
 Infection
 Neuropathy
 Foot trauma/injury
 Syndromes amaurosis fugax,
dysphagia lusoria, Leriche , TIA, CVA

Atherosclerosis risk factors

Nonmodifiable age , gender , family

Modifiable
stress
D.M., Hypertension, Smoking
Dyslipidaemia, obesity,
Review of systems

Cardiac

Cerebral

Renal

Gastrointestinal
Renovascular hypertension
10-20%of secondary hypertension
 Uncontrolled despite 2-3 meds
 Flash pul.oedema
 Hypokalaemia
 Captopril test
 Doppler US., MRA
 Angioplasty

Examination


Pulse, B.P., Edema
Local inspection
Colour elevation,
dependency
Skin trophic changes
Driness, hair, nails,
wasting
venous filling
Ulcers , Gangrene
Ulcers def., types
Gangrene
infarction
Necrosis
Examination

Palpation
temp. pulses, cap. Filling

Auscultation carotid , femoral
Investigation
Bood work, ECG, CXR
 Non invasive vascular lab
ankle/brachial index
exercise test , toe pressure
doppler ultrasound
Invasive
angiography, CT, MRA

Medical Management
1-Risk factors control
2-improve blood flow
aspirin, pentoxyphylline
clopidogrel, anticoagul.
Aspirin mechanism of action
Phosphlipids---arachidonic acid----(cyclooxygena)--endoperoxides:
In plt. --------thromboxane(throm.synth)
ATP-----ADP(plt
aggreg.+vasocons)
In blood vessel endoth.
Endoperox.----prostacyclin(stimulate adenyl
cyclase)
ATP------cAMP(plt
sgreg.+vasodil)
-----5AMP
Surgical management
For rest pain, ulcers, gangrene
 Embolectomy , thrombectomy,
 Vascular reconstruction
Endart.,repair,
resection+interposition,Bypass
Using saphenous vein (reverse/insitu)or
PTFE
 Amputation toe, transmet.,
symes,BK,AK

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