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Chapter 24 Vitamins and Minerals Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 1 Chapter 24 Lesson 24.1 Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 2 Learning Objectives • Identify the actions and indications for vitamins and minerals • List at least six products used to treat vitamin or mineral deficiencies Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 3 Vitamins • Natural chemical compounds found in animals and plants • Dietary considerations • Deficiencies • Antioxidants • MyPyramid • Table 24-1 Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 4 Vitamin A Action • Fat-soluble; aids visual adjustment; role in cell membrane stabilization Uses • Treat deficiencies, eye diseases, and night blindness Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 5 Vitamin A (cont.) Adverse Reactions • Hypervitaminosis Drug Interactions • Oral contraceptives, mineral oil, antihyperlipidemic drugs Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 6 Vitamin A (cont.) Nursing Implications • Lifespan requirements • Routes for administration • Patient teaching: nutritional sources Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 7 Vitamin B1 (Thiamine) Action • Water-soluble; coenzyme involved with carbohydrate metabolism; role in neurology Uses • Treatment of beriberi Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 8 Vitamin B1 (Thiamine) (cont.) Adverse Reactions • Sensitivity reactions • Parenteral precautions Drug Interactions • Poor stability with concurrent use of neutral or alkaline solutions Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 9 Vitamin B1 (Thiamine) (cont.) Nursing Implications and Patient Teaching • Food preparation • Dietary sources Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 10 Vitamin B2 (Riboflavin) Action • Water-soluble; precursor of two essential enzymes that deal with metabolism of fats, proteins, and carbohydrates • Related to the release of energy to cells • Active in the respiratory system Uses • Deficiency Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 11 Vitamin B2 (Riboflavin) (cont.) Drug Interactions • Oral contraceptives Nursing Implications and Patient Teaching • Storage • Change in urine color Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 12 Niacin Action • Water-soluble; part of two coenzyme systems that transfer hydrogen in intracellular respiration Uses • Prevent or treat deficiencies • Pellagra: symptoms Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 13 Niacin (cont.) Adverse Reactions • Dry skin, pruritis, skin rash, GI disorders, allergies, feelings of warmth, headache, tingling of the skin, transient flushing in the face and neck Drug Interactions • Antihypertensives Nursing Implications/Patient Teaching • Dietary sources Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 14 Pantothenic Acid Action • Synthesis of coenzyme A; role in release of energy in fats, proteins, and carbohydrates Uses • Treatment of paralytic ileus Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 15 Pantothenic Acid (cont.) Nursing Implications and Patient Teaching • Food preparation • Dietary sources Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 16 Vitamin B6 (Pyridoxine Hydrochloride) Action • Water-soluble; functions as coenzyme in metabolism of protein, fats, and carbohydrates Uses • Treat deficiencies due to inborn errors of metabolism, such as vitamin B6 dependency, B6-responsive chronic anemia, and other rare vitamin problems Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 17 Vitamin B6 (cont.) Adverse Reactions • None; pyridoxine dependency Drug Interactions • Oral contraceptives; levodopa • Concurrent use with chloramphenicol may prevent optic neuritis Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 18 Vitamin B6 (cont.) Nursing Implications and Patient Teaching • Storage • Dietary sources • Food preparation Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 19 Folic Acid (Vitamin B9) Action • Water soluble; required for normal erythropoiesis and nucleoprotein synthesis • Metabolized in the liver and changed to an active form Uses • Treat anemias caused by folic acid deficiencies; treat alcoholism, hepatic disease, hemolytic anemia; supplemental during infancy (formula), lactation, oral contraceptive use, and pregnancy Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 20 Folic Acid (cont.) Adverse Reactions • Folic acid is not toxic • Allergic reaction may manifest as bronchospasm, erythema, malaise, pruritis, or rash Drug Interactions • Antagonists: chloramphenicol and methotrexate Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 21 Folic Acid (cont.) Nursing Implications and Patient Teaching • RDA • Parenteral forms should be protected from light • Patient and family teaching: nutritional counseling; laboratory monitoring; need for medical follow-up Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 22 Vitamin B12 Action • Water-soluble and contains cobalt; produced by Streptomyces griseus; functions in fat, protein, and carbohydrate metabolism; part of the erythrocyte-maturing factor in the liver; required for DNA synthesis Uses • Treats all B12 deficiencies, pernicious anemia, other anemias, malabsorption syndromes, blind loop syndrome, pregnancy, chronic liver disease complicated by vitamin B12 deficiency, malignancy, thyrotoxicosis, renal disorders • Used in the flushing dose in Schilling test Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 23 Vitamin C Action • Acts in several enzyme systems; involved in intracellular oxidation-reduction potentials; aids in the change of folic acid and the metabolism of certain amino acids; aids in the absorption of calcium and iron; blocks the absorption of copper in the GI tract; protects vitamins A and E and polyunsaturated fatty acids; necessary for the formation of teeth, connective tissue, and capillaries for the synthesis of collagen; wound healing Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 24 Vitamin D Action and Uses • Fat-soluble • Three categories • Movement of calcium and phosphorus ions into small intestine, kidneys, and bone • Used to treat childhood rickets, adult osteomalacia, hypoparathyroidism, and familial hypophosphatemia Adverse Reactions: Vitamin D toxicity Nursing Implications and Patient Teaching Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 25 Vitamin E • Fat-soluble • Functions are not understood • Antioxidant: prevents cell membrane damage • Stabilizes the RBC wall to protect against hemolysis or destruction Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 26 Vitamin K Action • Fat soluble; helps hepatic formation of active prothrombin proconvertin, plasma thromboplastin component, and the Stuart factor Uses • Treat or prevent blood-clotting disorders Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 27 Chapter 24 Lesson 24.2 Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 28 Learning Objectives • Identify the actions and uses for minerals in the body • List at least six supplements used to treat mineral deficiencies • Prepare a teaching plan for patients who require mineral supplements Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 29 Minerals • 19 inorganic substances present in the body; 13 are essential to normal metabolism and function • Ions: positive and negative charges • Electrolytes • Table 24-2 Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 30 Calcium Action • Essential for muscular and neurologic activity; formation and repair of skeletal tissues; activates several enzymes that influence cell membrane permeability and muscle contraction; aids in blood clotting; activates pancreatic lipase; influences intestinal absorption of cobalamin; involved in the transmission of neurotransmitters and in metabolic processes; regulation of lymphocyte and phagocyte function through interaction with calmodulin Uses • Supplement when dietary levels are low Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 31 Calcium (cont.) Adverse Reactions • Hypercalcemia symptoms Drug Interactions • Vitamin D; phytic acid (found in bran and whole-grain cereals) Nursing Implications/Patient Teaching • Dietary sources Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 32 Fluoride Action • Strengthens enamel Uses • Reduces dental caries Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 33 Fluoride (cont.) Adverse Reactions • GI distress, urticaria, and malaise; excessive salivation, mottling of teeth, GI disturbances, and nausea are seen with overdosage Drug Interactions Nursing Implications and Patient Teaching • Administration; avoid glass containers when diluting fluoride; milk may decrease absorption Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 34 Iron Action • An essential mineral for the synthesis of myoglobin and hemoglobin; stimulates the hematopoietic system and increases hemoglobin to correct iron deficiency Uses • Treatment of symptomatic iron deficiency; prevent hypochromic anemia during infancy, childhood, pregnancy, and breastfeeding from other anemias; after some GI surgeries Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 35 Iron (cont.) Adverse Reactions Drug Interactions Nursing Implications and Patient Teaching • Nutritional sources, adverse effects Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 36 Magnesium Action • Maintains osmotic pressure, ion balance, bone structure, muscular contraction, and nerve conduction Uses • Deficiencies Adverse Reactions • Diarrhea Nursing Implications and Patient Teaching • Cardiac monitoring • Nutrition Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 37 Manganese Action • Activates many enzymes, assists in normal skeletal and connective tissue development, helps in the initiation of protein synthesis, and plays a part in the synthesis of cholesterol and fatty acids Uses • Dietary supplements for multiple deficiencies • Natural sources of manganese Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 38 Potassium Action • Principle intracellular cation of most body tissues; active in maintaining normal renal function, contraction of muscle, and transmission of nerve impulses Uses • Prophylactic – nephrotic syndrome, hepatic cirrhosis with ascites, hyperaldosteronism • Replacement therapy Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 39 Potassium (cont.) Adverse Reactions • Nausea, vomiting, diarrhea, abdominal discomfort, GI bleeding Drug Interactions • Contraindications Nursing Implications/Patient Teaching • Dilution and administration; monitoring of serum blood levels; dietary sources Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 40 Zinc Action and Uses • Essential for normal growth and tissue repair, mineralization of bone, detoxification, creation of DNA, synthesis of protein • Prevent zinc deficiency and aid wound healing Adverse Reactions • GI, nausea and vomiting; excessive dosage; intoxication Drug Interactions • Calcium Nursing Implications/Patient Teaching • Dosing and nutrition Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 41 Vitamin and Mineral Deficiencies • Assessment • Diagnosis • Planning • Implementation • Evaluation • Patient and family teaching Elsevier items and derived items © 2010, 2006, 2003, 2000 by Mosby, an imprint of Elsevier Inc. 42