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Transcript 
Do Magic Mushrooms have
medicinal value?
Joshua Root
Psilocybin Facts

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Contained in many different mushrooms.
Originated in East Africa
serotonin (5-HT)-2A/2C receptor agonist
ILLEGAL!
Effects
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Psilocin
Duration of 3-8 hours
Effects Continued
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Physical effects
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Increase in heart rate
Elevated blood pressure
Dilated Pupil
Nausea
Coldness and weakness in limbs
Effects Continued
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Emotional effects
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Strongly dependent on setting
Mood swings
Exaggeration of mood at ingestion
Effects Continued
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Sensory effects
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Visual
Auditory
Synthesia
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stimulation of one sensory or cognitive pathway
leads to automatic, involuntary experiences in a
second sensory or cognitive pathway
Proposed Medicinal Uses

Psychotherapy
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1950’s
Modern proposals
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OCD
Cluster Headaches
Body dysmorphic disorder
Treatment of OCD
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OCD
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4th most commonly diagnosed psychiatric
disorder
Complications
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Depression, suicidal tendencies, panic, substance
abuse, and interpersonal difficulties
Dysregulation of Serotonin
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5-HT reuptake inhibitors
OCD Treatment Findings

Dr. Francisco Moreno
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Completely removed symptoms
4-24 hours
Jeremy

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Fear of contamination
Symptoms relieved
Treatment of Cluster Headaches
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Triggered by a few different causes
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Interruption of sleep pattern, certain
medication, abnormal hormone levels, and
heavy smoking and drinking alcohol
Results

53 participants
85% aborted attack
 95% reported extension in remission
 42% benefited from sub hallucagenic doses

Treatment of Body Dysmorphic
Disorder

Mr. A


Relieved symptoms
Mrs. B

Relieved symptoms
Critiques and Comments

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Duration of positive results
Not a drug that can be used all the time
Less toxic than aspirin

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http://www.doitnow.org/pages/132.html
http://en.wikipedia.org/wiki/Psilocybin_mushrooms#Med
icinal_use
http://www.maps.org/research/psilo/azproto.html
http://www.ncbi.nlm.nih.gov/pubmed/16801660
http://en.wikipedia.org/wiki/Body_dysmorphic_disorder
http://www.msnbc.msn.com/id/16304852/
http://news.bbc.co.uk/2/hi/health/6210694.stm
http://www.shroomery.org/6233/PsychedelicMushrooms-Just-another-Drug-or-a-Powerful-Medicine
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