Download Drugs by Class

2003-2004
Review of Anticoagulants,
Thrombolytics and Anti-platelet Drugs
23 May 2017
6:50 AM
Abciximab
Antiplatelet
Anti-GPIIb/IIIa receptor antibody
Adalimumab
TNF inhibitor
Anti-TNF antibody
Used in rheumatoid arthritis
Allopurinol
Antigout
Antineoplastic (supporting agent)
Folic acid analogue
Xanthine oxidase inhibitor
Aminocaproic acid (EACA)
Procoagulant
Inhibitor of plasminogen activation
(decreases fibrinolysis)
Anistreplase
Thrombolytic
Streptokinase + plasminogen
Aprotinin
Procoagulant
Fibrinolytic inhibitor
Serine protease inhibitor (“serpin”)
Streptokinase inhibitor
Argatroban
Anticoagulant
Direct thrombin inhibitor
Aspirin
(Acetylsalicylic acid, ASA)
NSAID (acetylsalicylate)
Analgesic, Anti-inflammatory
Antipyretic, Antiplatelet
Irreversible cyclooxygenase inhibitor
Atorvastatin
Antihyperlipidemic
HMG-CoA reductase inhibitor
Auranofin
Disease modifying
anti-rheumatic drug (DMARD)
Gold salt
Oral
Aurothioglucose
Disease modifying
anti-rheumatic drug (DMARD)
Gold salt
Parenteral
Balsalazide
NSAID (salicylate)
Treatment of IBD
Beclomethasone
Adrenocorticosteroid
Glucocorticoid
Anti-inflammatory steroid
Inhaled
Betamethasone
Adrenocorticosteroid
Glucocorticoid
Anti-inflammatory steroid
Not by inhalation
Bivalirudin
Anticoagulant
Direct thrombin inhibitor
Bradykinin
Inflammatory mediator
Plasma, hypotension, pain
Budesonide
Adrenocorticosteroid
Glucocorticoid
Anti-inflammatory steroid
Inhaled OR treatment of IBD
C3a, C5a
Inflammatory mediators
Anaphylatoxins
Low molecular weight complement
cleavage products
Celecoxib
NSAID
Anti-inflammatory
Cyclooxygenase 2 (COX-2) inhibitor
Cholestyramine
Antihyperlipidemic
Bile acid binding resin (BABR)
Clofibrate
Antihyperlipidemic
Lipoprotein lipase activator
Clopidogrel
Antiplatelet
ADP receptor antagonist
Colchicine
Antigout only
Anti-inflammatory
Microtubule inhibitor
Colestipol
Antihyperlipidemic
Bile acid binding resin (BABR)
Cortisol (Hydrocortisone)
Adrenocorticosteroid
Glucocorticoid
Anti-inflammatory steroid
Cromolyn sodium
Mast cell stabilizer
Inhibits release of
mast cell mediators
Used prophylactically in asthma
Dalteparin
Anticoagulant
LMW Heparin
ATIII activator
Dexamethasone
Adrenocorticosteroid
Glucocorticoid
Antineoplastic
Antiemetic
Anti-inflammatory steroid
Not by inhalation
Diflunisal
NSAID
Analgesic, Anti-inflammatory
Antipyretic
Cyclooxygenase inhibitor
Dipyridamole
Antiplatelet
Phosphodiesterase inhibitor
(increases cAMP)
Drotrecogin alfa
(Activated Protein C)
Anticoagulant
Many actions
Treatment for septic shock
Enoxaparin
Anticoagulant
LMW Heparin
ATIII activator
Eptifibatide
Antiplatelet
GPIIb/IIIa antagonist
Erythropoietin (EPO)
Cytokine
Primary regulator of RBC synthesis
Etanercept
TNF inhibitor
Tumor necrosis factor receptor
+ Fc portion of IgG
Used in rheumatoid arthritis
Ezitimibe
Antihyperlipidemic
Cholesterol absorption inhibitor
Fenofibrate
Antihyperlipidemic
Lipoprotein lipase activator
Flunisolide
Adrenocorticosteroid
Glucocorticoid
Anti-inflammatory steroid
Inhaled
Fluticasone
Adrenocorticosteroid
Glucocorticoid
Anti-inflammatory steroid
Inhaled
Fluvastatin
Antihyperlipidemic
HMG-CoA Reductase Inhibitor
Gemfibrozil
Antihyperlipidemic
Lipoprotein lipase activator
Gold salts
auranofin, aurothioglucose
Disease modifying anti-rheumatic
drugs (DMARD)
Granulocyte-Colony
Stimulating Factor (G-CSF)
Cytokine
Granulocyte synthesis stimulator
Granulocyte/Monocyte-Colony
Stimulating Factor (GM-CSF)
Cytokine
WBC (granulocytes and monocyte)
synthesis stimulator
Heparin
Anticoagulant
ATIII activator
Hirudin
Anticoagulant
Direct thrombin inhibitor
(DTI)
Histamine
Inflammatory mediator
Stored in mast cells and basophils
Hydrocortisone
Adrenocorticosteroid
Glucocorticoid
Anti-inflammatory steroid
Hydroxychloroquine
Disease modifying
anti-rheumatic drug (DMARD)
4-Hydroxycoumarin
Oral anticoagulant
Vitamin K synthesis inhibitor
Ibuprofen
NSAID
Analgesic, Anti-inflammatory
Antipyretic
Reversible cyclooxygenase inhibitor
Indomethacin
NSAID
Analgesic, Anti-inflammatory,
Antipyretic
Cyclooxygenase inhibitor
Tocolytic
Uterine relaxant
Infliximab
TNF inhibitor
Anti-TNF monoclonal antibody
Treatment of IBD
Interferon alpha
Antiviral for hepatitis
Antineoplastic
Cytokine
Anti-angiogenesis
Interleukin 2
Cytokine
Antineoplastic
Interleukin 11
Cytokine
Antineoplastic (supporting agent)
Kallidin
Inflammatory mediator
Plasma, hypotension, pain
Ketoprofen
NSAID
Analgesic, Anti-inflammatory,
Antipyretic
Cyclooxygenase inhibitor
Lepirudin
Anticoagulant
Direct thrombin inhibitor (DTI)
Leukotriene B4 (LTB4)
Inflammatory mediator
Lipoxygenase product
of arachidonate metabolism
Chemotactic
Leukotrienes C4, D4, E4
(LTC4, LTD4, LTE4)
Inflammatory mediators
Cysteinyl leukotrienes
Peptidyl leukotrienes
SRS-A
Lipoxygenase products of
arachidonate metabolism
Lovastatin
Antihyperlipidemic
HMG-CoA reductase inhibitor
Meclofenamate
NSAID
Analgesic, Anti-inflammatory,
Antipyretic
Cyclooxygenase inhibitor
Mesalamine
(5-ASA)
NSAID (salicylate)
Treatment of IBD
Methylprednisolone
Adrenocorticosteroid
Glucocorticoid
Anti-inflammatory steroid
Not by inhalation
Montelukast
Leukotriene inhibitor
LTR1 and LTD4 antagonist
Asthma treatment
Naproxen
NSAID
Analgesic, Anti-inflammatory,
Antipyretic
Cyclooxygenase inhibitor
Nedocromil
Mast cell stabilizer
Inhibits release of mast cell
mediators
Used prophylactically in asthma
Nicotinic acid
Antihyperlipidemic
Inhibition of VLDL secretion (?)
Non-steroidal
Anti-inflammatory Drugs
(NSAIDs)
Analgesic, Anti-inflammatory,
Antipyretic
Cyclooxygenase inhibitors
Olsalazine
NSAID (salicylate)
Treatment of IBD
Phytonadione
Vitamin K
Warfarin antagonist
Piroxicam
NSAID
Analgesic, Anti-inflammatory,
Antipyretic
Cyclooxygenase inhibitor
Platelet Activating Factor
(PAF)
Inflammatory mediator
Lipid
Hypotensive
Pravastatin
Antihyperlipidemic
HMG-CoA reductase inhibitor
Prednisone
Adrenocorticosteroid
Glucocorticoid
Antineoplastic
Anti-inflammatory
Not by inhalation
Probenecid
Uricosuric
Adjunct in penicillin therapy
Probucol
Antihyperlipidemic
LDL oxidation inhibitor
Prostaglandin E2 (PGE2)
Dinoprostone (Dinoprost)
Oxytocic prostaglandin
Inflammatory mediator
Cyclooxygenase product of arachidonate
metabolism
Uterine stimulant
Cervical ripener
Prostaglandin F2 (PGF2)
Inflammatory mediator
Cyclooxygenase product of
arachidonate metabolism
Prostaglandin I2 (PGI2)
Prostacyclin
Inflammatory mediator
Inhibits platelet aggregation
Cyclooxygenase product of
arachidonate metabolism
Protamine Sulfate
Heparin antagonist
Rofecoxib
NSAID
Anti-inflammatory
Cyclooxygenase 2 (COX-2) inhibitor
Simvastatin
Antihyperlipidemic
HMG-CoA reductase inhibitor
Streptokinase
Thrombolytic
Rofecoxib
NSAID
Anti-inflammatory
Cyclooxygenase 2 (COX-2) inhibitor
Sulfasalazine
Disease modifying
anti-rheumatic drug (DMARD)
Metabolized to sulfonamide
+ salicylate (NSAID)
Treatment of IBD
Sulfinpyrazone
Uricosuric
Anti-gout
Sulindac
NSAID
Analgesic, Anti-inflammatory,
Antipyretic
Cyclooxygenase inhibitor
Thrombopoietin
Cytokine
Platelet synthesis stimulator
Thromboxane A2 (TXA2)
Autacoid
Promotes platelet aggregation
Cyclooxygenase product of
arachidonate metabolism
Ticlopidine
Antiplatelet
ADP receptor antagonist
Tissue plasminogen activators
alteplase, reteplase, tenecteplase
Thrombolytics
Triamcinolone
Adrenocorticosteroid
Glucocorticoid
Anti-inflammatory steroid
Inhaled
Tumor necrosis factor 
Cytokine
Antineoplastic
Urokinase
Thrombolytic
Warfarin
Anticoagulant
Vitamin K synthesis inhibitor
Zafirlukast
Leukotriene inhibitor
LTR1 and LTD4 antagonist
Asthma treatment
Zileuton
Leukotriene inhibitor
5-lipoxygenase inhibitor
Used in asthma