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UABD – Nebulized Liquid Inhaled Drugs MDI – Pressurized Meter Dose Inhaler Canister DPI – Dry Powder Inhaler Classifications by Mechanism I. Bronchodilators – Reduces bronchial smooth muscle constriction II. Corticosteroids – Reduce bronchial wall inflammation (swelling) III. Mucoactive Agents – has an effect on mucus IV. Antimicrobial – kills microorganisms V. Other I. Bronchodilators A. Short Acting 1) Beta Agonists: Albuterol 2.5 mg Xopenex 1.25 mg 2) Anti Cholinergic: Atrovent (Ipratropium Bromide) B. Long Acting Serevent (in Advair) Spiriva Short Acting Beta Agonists (beta-2) II. Steroids A. B. C. D. Flovent (in Advair) Pulmicort (MDI or UABD) Aerobid Qvar Must use as directed may take several doses/days to have therapeutic effect! Most come in MDI / DPI III. Mucoactive Agents • Normal saline – is the carrier in UABD treatments (MDI version doesn’t have) • Acetylcystine – Mucomyst 10%-20% solutions – irritating and smells! (give with a bronchodilator • NaHCO3- (Bicarbonate solution) • Pulmozyme – expensive $$$ IV. Antimicrobials • • • • Pentamidine – Pneumocystis Tobi (Tobramycin) G- bacteria Colystin – bacteria Ribrivirin V. Others • Chromolyn Sodium – allergy drug • Lidocaine – numbing medicine Da rules: • Don’t give drugs in the exact same class together: – examples: • Pulmicort & Flovent (both steroids) • Xopenex and Albuterol (both short acting beta agonists)