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Pediatric Chemotherapy Gina Brandl, RN BSN, MSN-Cand Nursing Instructor MSTC - Pediatrics 1 Objectives • The student will describe how chemotherapy works on cells normal and cancerous cells • The student will describe the common side effects of chemotherapy • The student will assist in developing a nursing care plan appropriate for the pediatric patient receiving chemotherapy 2 Chemotherapy • Chemotherapy – Specific drugs • Kill normal and cancerous cells • Given simultaneously – Achieves greatest cellular destruction • Alters DNA – Administration • Intrathecal (into spinal canal), oral or intravenous 3 Protocols • Type of cancer • Cell type • Location and spread • Drug • Dose • Interval of treatment Treatment for side effects Necessary laboratory studies (London et al., 2007) 4 Other Drugs Used • Other drugs used in cancer treatment – Colony-stimulating factor • Erythropoietin (Epoetin) • Filgrastim (Neupogen) – Antimetics • Ondansetron (Zofran) – Nutritional supports • Help to maintain nutritional support – TPN & Lipids 5 Side Effects of Chemotherapy • Occur when healthy cells are damaged – Occurrence • Immediately • Week to ten days • Months to years – Permanent or temporary – Includes: hair loss, mouth sores, constipation, bone marrow suppression, nausea and emesis, anorexia and weight loss 6 Side Effects of Chemotherapy • Hair loss • Mouth sores • Pain • Constipation • Bone marrow suppression • Nausea and vomiting • Anorexia and weight loss 7 Nursing Care Plan • Nursing diagnosis – Risk for infection r/t immunosupression, invasive procedures, malnutrition, or pharmaceutical agents • Goals, interventions with rationale and expected outcomes – Ineffective individual coping r/t situational crisis • Goals, interventions with rationale and expected outcomes 8 References London, M. L., Ladewig, P. W., Ball, J. W., & Bindler, R. C. (2007). Maternal & child nursing care (2nd ed.). Upper Saddle River, NJ: Prentice Hall. Saint Joseph’s Hospital. (2006). Pediatric oncology – Education & resource guide. Marshfield, WI; Ministry Health Care Steinbrook, R. (2007). Erthropoietin, the FDA, and oncology. The New England Journal of Medicine. 356(24), p. 248. Retrieved December 16, 2007, from the website http:proquest.umi.com.ezproxy.apollolibrary.com/pqdweb?did= 128822401901&sid=6&Fmt=3&clientid=13118&RQT=309&VNa me=PQD 9