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GGR / RCM database 2007 CBIP BCFI Ap Dr I. Latour, Dr L. Proost, Dr R. Vander Stichele, Dr J. Van Campen BCFI CBIP Belgisch Centrum voor Centre Belge Farmacotherapeutische Informatie d’Information Pharmacothérapeutique www.bcfi.be www.cbip.be 2 Book contains BCFI Belgisch Centrum voor 14 Chapters 1400 Hierarchical nodes, max 7 levels 3000 VOS/ DCI clusters 2500 Medicinal Products = Brandnames <6000 Medicinal Product Packages <1500 Ingredient names 500 Galenic terms >150 Firms Farmacotherapeutische Informatie www.bcfi.be 3 Site Book 440 pages Yearly updated – – – – – – General Practitionars Pharmacists Students … 8000 files / 93 Mb 2-weekly updated – Structure Content For – Free for – – – – – Health workers Students Every one .. 7 tables + ATC DPP history + link table => site 4-weekly updated For – – And .. – 100 000 users Structure MP Database NL = FR Off-line version (plain-html) PDA (plain –html) – General Practitionars Study projects Medical software Only Repertory >300 distribitions 3 milj hits/mnth (Nl) 2 milj hits/mnth (Fr) 4 5 6 7 SGML Book Database Site creations SGML check Distribution 8 www.BCFI.be www.CBIP.be 9 Info about database on site 10 Info about database on site 11 Database-tables Database tables Hyr (Hierarchy) MP (Brandname) MPP (Package) SAM (Composition) IR (Firm) / MpEq GAL (Galenic form) INNM (Ingredient) GGR_LINK (Patient Record => site) ATCDPP 13 Database tables Hyr (1400, 7 levels) – – Hierarchy Introduction & group-posology 14 Database tables: Hyr.dbf / dbt => Hierarchy , Introduction texts , Posology 15 Database tables: Hyr.dbf/dbt => Hierarchy , Introduction texts , Posology HYR CV MPGRP TITLE HYR • Dynamic 16 • can change trough deletion or insertion of new branches HYRCV •Persistent •same HYRCV = same meaning 16 Database tables: Hyr.dbf/dbt => Hierarchy , Introduction texts , Posology HYR CV MPGRP TITLE • Chapter • THGRP • THGRP • … (max 6 levels) • MPGRP ( = lowest level) 17 Database tables: Hyr.dbf/dbt HYR CV MPGRP TITLE 18 Database tables Hyr (1400, 7 levels) MP (2500) IR (160) MPEQ •Medicinal product •Brandname •Firm •WADA / Doping •Equivalents 19 Database tables: MP.dbf / dbt MP: Brandname + Firm + Doping 20 Database relations: HYR - MP MP: Brandname + Firm + Doping 21 Database relations: HYR – MP - IR MP: Brandname + Firm + Doping 22 Database relations: HYR - MP- IR - MPEQ MP: Brandname + Firm + Doping 23 Database tables Hyr (1400, 7 levels) MP (2500) MPP ( 5830) IR (160) / MPEQ GAL (500) Administratif information on Medicinal Product Packages • MPPCV (CNK) • Prescription label • Galenics • Content • Price • Reimbursement, On Prescription, Hospital use, “Cheap”-status 24 Database tables: MPP.dbf Administratif information on Medicinal Product Packages •Galenics compr. (séc.) •Content 30 x •On prescription status R/ •Soc Sec Reimburseement b •Reference Status •Public Price 7,43 25 Database tables: MPP.dbf Administratif information on Medicinal Product Packages •Galenics amp. i.v. – perf. •Content 10 x 20 ml •On prescription status / •Soc Sec Reimburseement / •Reference Status / •Public Price U.H. 26 Database tables: MPP.dbf Administratif information on Medicinal Product Packages •Galenics flacon perf. •Content 1x •On prescription status Rx •Soc Sec Reimburseement / •Reference Status / •Public Price 333.14 + 2 x 50 ml solv. 27 Database tables: MPP.dbf Content object of MPP •Content Quantity (CQ) 30 •Content Units (CU) x •Content Fluid Quantity (CFQ) •Content Fluid Units (CFU) •Add Quantity (AQ) •Add Units (AU) •Add Fluid Quantity (AFQ) •Add Fluid Units (AFU) •Add type (AType) 28 Database tables: MPP.dbf Content object of MPP •Content Quantity (CQ) 10 •Content Units (CU) x •Content Fluid Quantity (CFQ) 20 •Content Fluid Units (CFU) ml •Add Quantity (AQ) •Add Units (AU) •Add Fluid Quantity (AFQ) •Add Fluid Units (AFU) •Add type (AType) 29 Database tables: MPP.dbf Content object of MPP •Content Quantity (CQ) 1 •Content Units (CU) x •Content Fluid Quantity (CFQ) •Content Fluid Units (CFU) •Add Quantity (AQ) 2 •Add Units (AU) x •Add Fluid Quantity (AFQ) 50 •Add Fluid Units (AFU) ml •Add type (AType) solv. 30 Database relations: MP - MPP 31 Database relations: MP – MPP - GAL 32 Database relations: MP – MPP - GAL 33 Database fields: MPP Reference class = CNK mOno, mUlti, Combi Prescription label Ranking inside MP Name specifier: “TTS: 10” Combi preparations: “6 + 5 + 11” 34 Database tables Hyr (1400, 7 levels) MP (2500) MPP ( 5830) SAM (>7000) IR (160) / MPEQ GAL (500) INNM (1400) Composition of Medicinal Product Packages •Pharmaceutical Product (PP) info •Ingredient •Strength 35 Database tables: SAM.dbf Composition of Medicinal Product Packages Ingredient (InCv) “0483” Quantity (InQ) 2 Units(InU) mg To Add (+) or Solved (/) (Add) - Quantity of Solvent base (InBasQ) - Units of Solvent base (InBasU) - InQ2 - InU2 - Dim - 36 Database tables: SAM.dbf Composition off Medicinal Product Packages Ingredient (InCv) “0123” Quantity (InQ) 5 Units(InU) mg To Add (+) or Solved (/) (Add) / Quantity of Solvent base (InBasQ) 1 Units of Solvent base (InBasU) ml InQ2 - InU2 - Dim - 37 Database tables: SAM.dbf Composition off Medicinal Product Packages Ingredient (InCv) “1234” Quantity (InQ) 250 Units(InU) - To Add (+) or Solved (/) (Add) à Quantity of Solvent base (InBasQ) - Units of Solvent base (InBasU) - InQ2 1000 InU2 UI poudre Dim - 38 Database tables: SAM.dbf Composition off Medicinal Product Packages InRank 1 2 Ingredient (InCv) “0115” “0862” Quantity (InQ) 250 125 Units(InU) mg mg - - Quantity of Solvent Base (InBasQ) - - Units of Solvent Base (InBasU) - - Max Ingredient Quantity (InQ2) - - Max Ingredient Units (InU2) - - Dim - - Add (+) or Solved (/) or “à” (Add) 39 Database relations: MPP - SAM 40 Database relations: MPP - SAM 41 Database fields: SAM 42 Database tables Hyr (1400, 7 levels) MP (2500) MPP ( 5830) SAM (>7000) GGR_LINK (5830) IR (160) / MPEQ GAL (500) INNM (1400) 43 Database tables: GGR_Link.dbf 44 Database tables: GGR_Link.dbf 45 Database tables: GGR_Link.dbf 46 Database tables: GGR_Link.dbf 47 Database tables: GGR_Link.dbf 48 Database tables Hyr (1400, 7 levels) MP (2500) MPP ( 5830) SAM (>7000) IR (160) / MPEQ GAL (500) INNM (1400) GGR_LINK (5830) ATCDPP (>12000) 49 Database tables: AtcDpp.dbf Atc & Dpp history DDD Quantity In Present GGRCM ? MppCv = CNK MppNm Nl (c,50) Mppnm Fr(c,50) Off Market Date ATC code Doses Pro Package DDD Units ATC title (English) 50 ATC = A natomical T herapeutical C hemical Classification 51 ATC : PERDOLAN 500MG COMP EFF 20X500MG ATC code : N02BE01 N NERVOUS SYSTEM 02 ANALGESICS B PYRAZOLONES E ANILIDES 01 paracetamol 52 ATC : USE ? Group medication with the same qualitatif content independent of packsize, manufacturer, label or country 53 ATC : USE ? Group medication with the same qualitatif content independent of packsize, manufacturer, label or country Compare drug utilisation 54 ATC : drug utilisation comparison DDD : Defined daily dose = is the assumed average maintenance dose per day for a drug used for its main indication in adults. DDU : Daily dose unit DPP : Ddds per package 55 ATC : drug utilisation comparison ATC : MISUSE ? DDDs do not necessarily reflect therapeutically equivalent doses of different drugs Price comparisons on inclusion of drugs in ATC groups 57 This presentation is found at www.BCFI.be/ www.CBIP.be => download/ télécharger databank versie / banque de données uitlegnota / note explicative powerpoint presentation 58 58 BCFI / CBIP relational database: 59 how it works Questions? 60 60