Download OI Jeopardy - UCLA Health

Ois general
PCP
Cryptococcus-
Toxoplasma-
10
10
10
10
20
20
20
20
30
30
30
30
40
40
40
40
50
50
50
50
OIs- 10
• OIs are the most common presentation of
chronic treated HIV infection
OIs– 10
• No
OIs - 20
• OIs usually present when CD4< 300
OIs – 20
• No usually when CD4 < 200
OIs - 30
• The most common OI in HIV infection
OI – 30
• Oral candidiasis
OI - 40
• Name 2 of the most life threatening OIs
OI– 40
• PCP
• Cryptococcosis
OI- 50
• CMV presents when CD4 < 50 and prophylaxis
with antivirals should be started
OI– 50
• Antivirals are not part of prophylaxis for HIV
related OIs
PCP - 10
• One of the most common causes of death
from AIDS in 80s
PCP – 10
• Yes
PCP- 20
• PJP is a common environmental parasite
MHC – 20
• IT is a fungus not a parasite
PCP- 30
• Drug of choice for PCP prophylaxis and
alternative if patient has allergy
PCP– 40
• Diagnostic test of choice for PCP
PCP- 40
• Diagnostic test of choice for PCP
PCP– 40
• Sputum DFA for PCP
PCP- 50
• One scenario that patient should stay on
prophylaxis for PCP for life
PCP– 50
• If patient had episode of PCP with CD4 > 200
Cryptococcus- 10
• The most common manifestation of
cryptococcus infection
Cryptococcus– 10
• CNS infection
Cryptococcus- 20
• Why frequent LPs are needed with crypto
meningitis?
Cryptococcus– 20
• Increased ICP
Cryptococcus - 30
• Name two diagnostic tests for Cryptococcus
infection
Cryptococcus– 30
• Cryptococcus antigen
• Fungal culture
Cryptococcus - 40
• Name the induction therapy for Cryptococcus
Cryptococcus– 40
• Amphotericin + 5FC
Cryptococcus - 50
• This regimen has been used in resource poor
countries for treatment of Cryptococcus
infection
Cryptococcus– 50
• High doses fluconazole (>800 mg) plus 5FC
Toxoplasma- 10
• Name 2 presentation of toxoplasmosis
Toxoplasma- – 10
• Fever, headaches, seizures, no clinical
manifestations
Toxoplasma - 20
• A common carrier of toxoplasma (animal)
Toxoplasma– 20
• Cat
Toxoplasma - 30
• The antibiotic that is used for prophylaxis for
Toxoplasma is also effective for other OIs
Toxoplasma– 30
• Bactrim is also effective against PCP
Toxoplasma- 40
• Name alternative antibiotics for Toxoplasma (if
there is allergy to the drug of choice)
Toxoplasma– 40
• Clindamycin, pyrimethamine
Toxoplasma- 50
• Duration of prophylaxis for toxoplasma
Toxoplasma- 50
• Discontinue ppx when CD4>200 > 3 months