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Ch 7-1 Cellular Reproduction •Interphase & Mitosis make up Cell Cycle (pg 174) •The mitotic (M) phase of the cell cycle alternates with the much longer interphase. •The M phase includes mitosis and cytokinesis. •Interphase accounts for 90% of the cell cycle. Terms for the hereditary material (DNA) found in the nucleus. Chromatin—dense mass of material within the nucleus; composed of individual chromosomes Chromosomes—structure that carries the genes; composed of protein & DNA Chromatid—each individual strand of the double stranded chromosome resulting from replication in Prophase. Centromere—point at which sister chromatids are attached *DNA, Protein spool, Chromatin, & Chromosomes (Illustrations on pg 173) The Cell Cycle Interphase—(resting stage) • Not a part of mitosis • Cell grows & carries on all life activities • DNA & Chromosomes replicate; producing a 2nd set of chromosomes. • Interphase has three subphases: – the G1 phase (“first gap”) centered on growth, – the S phase (“synthesis”) when the chromosomes are copied, – the G2 phase (“second gap”) where the cell completes preparations for cell division, • Mitosis (M)—the cell divides thru the process by which chromosomes are duplicated & distributed to daughter nuclei; each daughter nucleus carries the same set of genetic information as the parent nucleus. • There are four stages of Mitosis! – Prophase – Metaphase – Anaphase – Telophase Prophase • Chromosomes shorten & thicken becoming visible • Spindle fibers & asters form • Centrioles move towards opposite poles • By the end, the nucleus & nucleolus have completely disappeared Metaphase • Paired chromatids (chromosomes) are lined up at the equator. • Microtubules are attached at the centromere. Anaphase • Centromere splits & the two sister chromatids separate from one another & start moving towards opposite poles…or sides of the cell. Telophase • Cytoplasm begins pinching in towards the center of the cell…(cytokinesis) • Spindle fibers & asters disappear • Two new nuclei are formed • Chromosomes become a mass of chromatin again • The two daughter cells separate into two individual cells • Animal Cell—pinching in a cell membrane to separate the two cells • Plant Cell—a cell plate forms which will eventually become the cell wall…also they go thru mitosis without the centrioles.