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5.2 Mitosis and Cytokinesis KEY CONCEPT Cells divide during mitosis and cytokinesis. 5.2 Mitosis and Cytokinesis • One long continuous thread chromatid of DNA coiled around histones (proteins) is called chromatin. • One half of a duplicated chromosome is a chromatid. • Sister chromatids are held together at the centromere. • Telomeres protect DNA and do not include genes. centromere telomere Condensed, duplicated chromosome 5.2 Mitosis and Cytokinesis Chromosomes condense at the start of mitosis. • DNA wraps around proteins (histones) that condense it. DNA double helix DNA and histones Chromatin Supercoiled DNA 5.2 Mitosis and Cytokinesis B. Mitotic Phase- Mitosis and cytokinesis produce two genetically identical daughter cells. Parent cell • 1.Interphase prepares the cell to divide. • DNA is duplicated. centrioles spindle fibers centrosome nucleus with DNA 5.2 Mitosis and Cytokinesis Cell structures and mitosis • Centrosomes-organelle that is the main microtubule organizing center. • Aster-cellular star shaped structure that forms around the centrosome-made of microtubules • Equator-mid section of the dividing cell • Cleavage furrow - indentation that begins the formation of the new cell membrane • Cell plate- the new cell wall • Kinetorchore fibers- attachment points on the centromere where the chromosomes are held together to make an X • Spindle- fibers that separate the chromosomes • Microtubules-hollow, protein fibers and rods. • Cytokinesis-division of the cytoplasm results two daughter cells. 5.2 Mitosis and Cytokinesis 2.During prophase, chromosomes condense, nuclear membrane, nucleus, and nucleolus disappear, spindle fibers form, centrioles make spindle fibers 5.2 Mitosis and Cytokinesis – 3.During metaphase- spindle fibers randomly align sister chromatids in the middle of the cell (equator) 5.2 Mitosis and Cytokinesis – 4.During anaphase- spindle fibers retract and pull the sister chromatids opposite sides of the cell (poles) 5.2 Mitosis and Cytokinesis – 5.During telophase- chromosomes uncoil, nuclear membrane reforms, nucleolus reforms. 5.2 Mitosis and Cytokinesis • 6.Cytokinesis-division of the cytoplasm – In animal cells, the membrane pinches closed at a point called cleavage furrow. – In plant cellsvacuoles join together and form a cell plate. Result-2 identical daughter cells with identical copies of genetic materialDNA 5.2 Mitosis and Cytokinesis 5.2 Mitosis and Cytokinesis 5.2 Mitosis and Cytokinesis 5.2 Mitosis and Cytokinesis 5.2 Mitosis and Cytokinesis