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Cell Structure & Function Cell Organelles (part a) Foothill High School Science Department Cytoskeleton Key Concept: The Cytoskeleton is a network of protein filaments that helps the cell to maintain its shape, The Cytoskeleton is also involved in many forms of cell movements Contains: Microtubules & Microfilaments Foothill High School Science Department Microtubules • Hollow tubes of protein about 25 nanometers in diameter • Maintain cell shape • Provide “Tracks” along which cell organelles move • Especially important during cell division Foothill High School Science Department Microtubules-Green Nucleus Foothill High School Science Department Microtubules - TEM Foothill High School Science Department Microtubules & Cell Division • Separates Chromosomes Animal Plant Foothill High School Science Department Centriole? Yes No Microtubules & Locomotion Photomicrograph TEM Cilia Foothill High School Science Department Microtubules & Locomotion Photomicrograph Flagella Foothill High School Science Department Microtubules & Locomotion Photomicrograph Flagella Pili Flagella E. coli www.siue.edu/~cbwilso/ Ecoli_flagella.jpg Foothill High School Science Department Microfilaments • 7 Nanometers in diameter • Form Extensive Networks To Support Cells • Also used as “Tracks” for organelles being moved by motor proteins Foothill High School Science Department Microfilaments - Green Microtubules Microfilaments Foothill High School Science Department Nucleus First Identified By Robert Brown in 1831 Key Concept: The nucleus controls most cell processes and contains the hereditary information of DNA (deoxyribonucleic acid) Foothill High School Science Department Nucleus Frog Blood Nucleated RBC’s (normal) Neutrophile (White Blood Cell) Foothill High School Science Department Nucleus Human Cheek Cells Nucleus Foothill High School Science Department Nucleus Red Blood Cell Segmented Neutrophile Band Cell Human Blood Smear Eosinophile Lymphocyte Basophile Foothill High School Science Department Chromatin & Chromosomes Chromatin – Granular material within the nucleus which is a combination of DNA bound to protein Chromosome – Condensed Chromatin that forms during cell division Foothill High School Science Department Nucleolus Dense area within the nucleus which is where ribosome formation begins Nucleolus Chromatin Foothill High School Science Department Nuclear Envelope • Double Membrane • Surrounds Chromatin • Contains thousands of Nuclear Pores which allow the transfer of material in and out of the Nucleus Foothill High School Science Department Nuclear Pores Foothill High School Science Department Nuclear Pore – TEM Foothill High School Science Department Ribosomes • Make Proteins • Made From r-RNA (ribosomal RNA) + Protein Subunits (from Nucleolus) • 0.025 micrometers in diameter • Translate m-RNA (messenger RNA) into protein Foothill High School Science Department Ribosomes Foothill High School Science Department Ribosome Amino Acid Being Added To The Protein Chain transfer RNA tRNA (We will learn about later) messenger RNA mRNA (We will learn about later) Foothill High School Science Department Endoplasmic Reticulum Key Concept: The endoplasmic reticulum is the organelle in which components of the cell membrane are assembled and some proteins are modified. Foothill High School Science Department Rough Endoplasmic Reticulum • Synthesizes Proteins • Looks rough because of ribosomes that stud the surface. – Proteins move from the ribosomes, directly into the Endoplasmic Reticulum where the proteins may be further modified. Foothill High School Science Department Rough Endoplasmic Reticulum Nucleus Rough ER Smooth ER Foothill High School Science Department Free Standing Ribosomes • Manufacture Proteins For Use In The Cell Foothill High School Science Department Smooth Endoplasmic Reticulum • This Section Of The ER does not have any Ribosomes attached. • Smooth ER typically manufactures lipids to make membranes Foothill High School Science Department Golgi Apparatus • Proteins produced by the Rough ER move into the Golgi Apparatus. • Consists of a stack of membranes like stacks of pita bread Foothill High School Science Department Golgi Apparatus Key Concept: Enzymes in the Golgi apparatus attach carbohydrates & lipids to proteins. Products are then sent to their final destination. Foothill High School Science Department Foothill High School Science Department Vesicles Small vacuoles involved in the transport of substances within the cell Foothill High School Science Department