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T-cell B-cell, plasma cell Growth inhibition Epithelium Low: Upregulation of ICAM1 Low: Upregation of IGF-1 receptor High: Exfoliation Inhibition of Ig production Histamine release PGD2 synthesis Mast cell ECP TGF b release proteoglycan accumulation migration Growth inhibition Decreased viability Fibroblast Cancer cells Decreased cfu Growth inhibition Death, paralysis ECP E.coli S.aureus Helminths Parasites Decreased infectivity Respiratory syncytial virus