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Electrical Geodesics Inc & Neuroinformatics Center, UO, 15 Nov. 2013
Ensemble Synchronization in
Schizophrenia
Kaushik Majumdar, ISI Bangalore
Joint work with Pradeep D. Prasad
(ISI), John P John (NIMHANS), H. N.
Harsha (Nitte University)
https://sites.google.com/site/isicng/
(Computational Neuroscience Group)
Video Synchronization:
Snapshot
Prasad et al. Clin. EEG Neurosci. 44(1): 16 – 24, 2013
Pairwise Hilbert Phase
Synchronization
Hilbert Transformation and
Instantaneous Phase

s( )
H ( s(t ))  
d
  t  
1
 H ( s)) 

 (t )  arctan 
 s(t ) 
Phase Synchronization
Prasad et al. 2012
Cross Modal Task
Videos
 Healthy control subject
http://youtu.be/4aFMQFhiRHw
 Patient with schizophrenia
http://youtu.be/-TECG5XQhB4
Multi-channel synchronization
Single Trial Ensemble
Synchronization
Trial Averaged Ensemble
Synchronization
ERSP & ITC
Trial Selection
Classification by Logistic
Regression
 3 dimensional feature space:
1. Ensemble right hemispheric
synchronization.
2. Ensemble left hemispheric
synchronization.
3. Response latency.
2 Dimensional Projection of 3
Dimensional Feature Space
Incongruent
stimulus
Cross is
patient with
schizophrenia
square is
healthy
control
subject
2 Dimensional Projection of 3
Dimensional Feature Space
Congruent
stimulus
Plus is patient
with
schizophrenia
circle is
healthy control
subject
2 Dimensional Projection of 3
Dimensional Feature Space
Neutral stimulus
Star is patient
with
schizophrenia
diamond is
healthy control
subject
Average Accuracy
Probabilistic Score
Reference
 P. D. Prasad, H. N. Halahalli, J. P.
John and K. Majumdar, “Single-trial
EEG classification using logistic
regression based on ensemble
synchronization,” accepted in IEEE
Journal on Biomedical and Health
Informatics.
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