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Lecture 2 Lab
Histology of Gastrointestinal Tract
Quiz Presentation
AKT
Slide courtesy of Dr. Bruce Babiarz, Rutgers University
Esophagus
(Masson's trichrome)
8
7
2
6
5
1
4
3
CM = inner circular layer of
muscularis propria
E = epithelium
G = seromucous gland
LM = outer longitudinal
layer of muscularis propria
LP = lamina propria
Ly = lymphoid aggregates
MM = muscularis mucosae
MP = muscularis propria
SM = submucosa
Non-keratinized stratified
squamous mucosa
Extension of the
lamina propria
Submucosa
Muscularis
(splayed apart)
Identify the various
layers and the
esophageal glands.
Slide courtesy of Dr. Lutz Slomianka, Western Australia University
Identify the various layers and
the esophageal glands.
?
Slide courtesy of the University of Southern California, College of Dentistry
1 = non-keratinized
stratified squamous
epithelium
2 = lamina propria
3 = muscularis
mucosa
* = brunner gland
Circle – meissner’s
plexus
4 = submucosa
? = connective
tissue
5 = inner circular
layer of muscularis
6 = outer longitudinal
layer of the
muscularis
Components of Wall of GI Tract
1
CM = circular
layer of
smooth
muscle
3
2
Auerbach’s
myenteric
plexus
LM =
longitudinal
layer of
smooth
What is this?
Slide courtesy of Virtual Hospital
Type of epithelium?
Squamous
Type of epithelium?
Columnar
pylorus
Normal GE
junctions
Rugae
Stomach
Histology Lab
Tubular GI
Stomach
Name the types of
cells produced in each
area of the stomach
Stomach
Esophagus
- Have squamous
epithelium
Cardia of stomach
- Have glandular
material
Identify the
two organs
seen in the
slide.
Slide courtesy of Dr. Roger Wagner, University of Delaware
Semi-aligned drawing & micrograph of gastric glands
What is this?
Body of the stomach
C = circular layer of
muscularis externa
GP = gastric pits
L = longitudinal
layer of muscularis
externa
M = mucosa
MM = muscularis
mucosa
O = oblique layer of
muscularis externa
Stomach: Pyloric area Immunostain for Gastrin
MM =
muscularis
mucosa
G = gastrin
secreting
enteroendocrin
e cells
P = gastric pits
Slide courtesy of Dr. Bruce Babiarz, Rutgers University
Slide courtesy of Dr. Bruce Babiarz, Rutgers University
Medium power
view of the cardiac
stomach. Identify
the mucosa
(surface mucous
cells, lamina
propria and
muscularis mucosa.
Also identify the
submucosa.
Slide courtesy of Dr. Roger Wagner, University of Delaware
Low power view of
gastric glands.
Identify the
mucosa (epithelia,
lamina propria
and muscularis
mucosa),
submucosa,
muscularis
externa and
serosa.
Slide courtesy of Dr. Roger Wagner, University of Delaware
Low power view of gastric
glands. Identify the pit,
neck and glandular
portions of the glands.
Also identify parietal and
chief cells.
Slide courtesy of Dr. Roger Wagner, University of Delaware
Slide courtesy of Dr. Bruce Babiarz, Rutgers University
Small Intestine
Histology Lab
Tubular GI
Where are these pics from?
Slide courtesy of Virtual Hospital
What is this?
Slide courtesy of Virtual Hospital
What is this?
Slide courtesy of Virtual Hospital
What is this?
Slide courtesy of Virtual Hospital
Slide courtesy of Dr. Bruce Babiarz, Rutgers University
What is this?
Slide courtesy of Dr. Bruce Babiarz, Rutgers University
What area
of the small
intestine?
Duodenum
Identify the region
of the small
intestine. Also
identify the
mucosa
(epithelium,
lamina propria,
muscularis
mucosa)
submucosa,
Brunner’s glands,
muscularis externa
and serosa.
Slide courtesy of Dr. Roger Wagner, University of Delaware
Panoramic view of the
small intestine.
Identify the mucosa
(epithelium, lamina
propria and
muscularis mucosa),
submucosa,
muscularis externa
and serosa.
Distinguish between
the villi and plica
circulares.
Slide courtesy of Dr. Roger Wagner, University of Delaware
What area of the
GI tract is this?
Ileum with Peyer’s patches
Low power view of the small
intestine. Identify the mucosa
(epithelium, lamina propria
and muscularis mucosa) and
submucosa, muscularis
externa and serosa.
Distinguish between the villi
and plica circulares.
Slide courtesy of Dr. Roger Wagner, University of Delaware
Medium power view of
intestinal villi. Distinguish
between absorptive and
goblet cells. Identify the
lamina propria and the
lacteal.
Slide courtesy of Dr. Lutz Slomianka, Western Australia University
Slide courtesy of Dr. Bruce Babiarz, Rutgers University
Large Intestine
Histology Lab
Tubular GI
Where is this?
Slide courtesy of Virtual Hospital
Identify the
intestinal crypts,
absorptive cells,
goblet cells,
lamina propria
and muscularis
mucosa.
Slide courtesy of Dr. Roger Wagner, University of Delaware
Anus
Squamous
epithelium
What is
this?
Low power view of
the rectoanal
junction.
Black line = line of
hilton
Slide courtesy of Dr. Roger Wagner, University of Delaware
Low power view
of the rectoanal
junction. Identify
the line of Hilton.
Slide courtesy of Dr. Lutz Slomianka, Western Australia University
Identify the
mucosa
(epithelium, lamina
propria and
muscularis mucosa)
and submucosa.
Slide courtesy of Dr. Lutz Slomianka, Western Australia University
Identify the
mucosa
(epithelium,
lamina propria
and muscularis
mucosa) and
submucosa. Also
identify the
intestinal crypts.
Slide courtesy of the University of Southern California, College of Dentistry
Slide courtesy of Dr. Lutz Slomianka, Western Australia University
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