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Digestion, Absorption
and Transport
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestion
• Basic anatomy of the GI tract
–mouth  esophagus  stomach
 small intestine  large
intestine  rectum  anus
–lumen
Copyright 2005 Wadsworth Group, a division of Thomson Learning
GI Tract
Anatomy
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestion
• Mouth
–Tongue
–Teeth
•Mastication
Copyright 2005 Wadsworth Group, a division of Thomson Learning
The Teeth
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestion
• Pharynx
• Epiglottis
• Esophagus
–Esophageal sphincters
–Bolus
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestion
• Stomach
–Chyme
–Pyloric sphincter
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Stomach
Muscles
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestion
• Small intestine
–Duodenum
–Jejunum
–Ileum
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestion
• Gallbladder
• Pancreas
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestion
• Large intestine = colon
–Ileocecal valve
–Appendix
• Rectum
–Anus
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Muscular Action
of Digestion
• Peristalsis
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Peristalsis & Segmentation
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Muscular Action
of Digestion
• Stomach action
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Muscular Action
of Digestion
• Segmentation
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Muscular Action
of Digestion
• Sphincter contractions
–Reflux
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Secretions
of Digestion
• Catalysts
–Hydrolysis
–Digestive enzymes
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Secretions
of Digestion
• Saliva
–Salivary glands
•Water, salts,
mucus,
enzymes
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Secretions
of Digestion
• Stomach
–Gastric juice
–Gastric glands
•Water, enzymes,
hydrochloric acid
(HCl)
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Secretions
of Digestion
• Stomach
–Goblet cells
•Mucus
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Secretions
of Digestion
• Pancreas
–Pancreatic juice
•Enzymes, bicarbonate
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Secretions
of Digestion
• Liver
–Bile
•Emulsifier
• Gallbladder
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Secretions
of Digestion
• Protective factors
Copyright 2005 Wadsworth Group, a division of Thomson Learning
The Final Stage
• Stools
• Colon
–Fermentation of undigested
residues
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestion of
a Sandwich
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestion of
a Sandwich
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Absorption
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Absorption in the
Small Intestine
• Villi
–Microvilli
–Capillaries and lacteals
–Chylomicrons
• Crypts
Copyright 2005 Wadsworth Group, a division of Thomson Learning
The Small Intestinal Villi
Copyright 2005 Wadsworth Group, a division of Thomson Learning
The Small Intestinal Villi, cont’d
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Circulatory Systems
• Vascular system
–Heart
–Arteries
–Capillaries
–Veins
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Circulatory Systems
• Vascular system
–Portal vein
–Hepatic vein
Copyright 2005 Wadsworth Group, a division of Thomson Learning
The
Liver
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Circulatory Systems
• Lymphatic system
–Lymph
–Thoracic duct
• Subclavian vein
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Regulation
• Homeostasis
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Regulation
• Hormones
–Gastrin
–Secretin
–Cholecystokinin = CCK
–Gastric-inhibitory peptide = GIP
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestive Problems
• Choking
–Trachea
–Larynx
–Heimlich maneuver
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Heimlich
Maneuver
Digestive Problems
• Vomiting
• Diarrhea
–Irritable bowel syndrome
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestive Problems
• Constipation
• Hemorrhoids
• Diverticula
–Diverticulosis
–Diverticulitis
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Diverticula in
the Colon
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestive Problems
• Belching
• Gas
• Hiccups
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestive Problems
• Heartburn = gastroesophageal
reflux
–Antacids and acid controllers
–Indigestion
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Gastroesophageal
Reflux
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Digestive Problems
• Ulcers
–Peptic ulcer
–Helicobactor pylorii infection
–Use of certain anti-inflammatory
drugs
–Disorders that cause excessive
acid secretion
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Strategies
for GI
Problems
Copyright 2005 Wadsworth Group, a division of Thomson Learning
Copyright 2005 Wadsworth Group, a division of Thomson Learning
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