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Histology: The Digestive System By Andrew W. Parsons Copyright 2000, All Rights Reserved. Material is in logical order: see texts, lab. outline for characteristics To advance to next slide: -click mouse or “page down” To return to the previous slide: - press “page up” Histology: four layers: -Mucosa -epithelium: stratified squamous or simple columnar -lamina propria: areolar c.t. -muscularis mucosa: smooth muscle -Submucosa: dense irregular c.t. -Muscularis externa: skeletal muscle (upper esophagus), smooth muscle elsewhere (-oblique layer: stomach only) -circular layer -longitudinal layer -Serosa or adventitia: simple squamous epith., areolar c.t. The Esophagus -Stratified squamous epithelium -Skeletal muscle in m. externa -Adventitia The esophagus: 100X Mucosa Submucosa Muscularis externa Adventitia The esophagus: 450X Mucosa Epithelium Lamina propria Muscularis mucosa Submucosa The esophagus: 100X Adventitia Muscularis externa Submucosa Mucosa The esophagus: 450X Muscularis externa Submucosa Muscularis mucosa Lamina propria Epithelium The Stomach -Simple columnar epithelium -No villi -Epithelium all goblet cells -Glands are not obvious -Smooth muscle in m. externa The stomach: 40X Muscularis externa: THREE layers inner oblique, middle circular, outer longitudinal Submucosa Mucosa Mucosa of the stomach: 450X Lamina propria: areolar c.t. Epithelium: all goblet cells Glands are NOT obvious Mucosa & submucosa of the stomach: 450X Mucosa Muscularis mucosa Gastric glands are NOT obvious Submucosa Submucosa & muscularis externa of the stomach: 450X Muscularis mucosa Submucosa Muscularis externa The Small Intestine -Villi -Simple tubular glands The small intestine: 40X Villus Muscularis externa: -circular -longitudinal Submucosa Intestinal glands Mucosa Villus of small intestine: 450X Lamina propria Epithelium Mucosa & submucosa of the small intestine: 450X Intestinal gland Lamina propria Submucosa Mucosa Muscularis mucosa Submucosa & muscularis externa of the small intestine: 450X Submucosa Muscularis externa: inner circular layer Muscularis externa of the small intestine: 450X Muscularis externa: inner circular layer Muscularis externa: outer longitudinal layer Submucosal or Brunner’s glands of the duodenum: 100X Mucosa Submucosa with submucosal glands Muscularis externa: inner circular layer The Colon -No villi -Simple tubular glands -M. externa has “folds” The colon: 40X Submucosa Muscularis externa: Mucosa Mucosa of the colon: 450X Intestinal gland Epithelium Lamina propria Mucosa & submucosa of the colon: 450X Intestinal gland Submucosa Mucosa Muscularis mucosa Lamina propria The colon: 450X Muscularis externa -Inner circular layer: has these “funny” folds Submucosa Mucosa Muscularis mucosa Muscularis externa of the colon: 450X Muscularis externa -Inner circular layer: has these “funny” folds Serosa & muscularis externa of the colon: 450X Outer longitudinal layer Serosa Inner circular layer The Liver -Hepatic lobules -Central vein & sinusoids -Triads: -Bile ducts -Hepatic artery -Hepatic portal vein The Liver: 40X Hepatic lobule The Liver: 450X Central vein Hepatocytes Sinusoids Triad of the Liver: 450X Hepatic portal vein Hepatic artery Bile duct Triad of the Liver: 450X Hepatic artery Hepatic portal vein Bile duct The Pancreas -Pancreatic acini -Pancreatic islets The Pancreas: 40X Islet Acinous glands The Pancreas: 450X Islet Acinous glands The End Presentation & Photographs by Andrew W. Parsons Copyright 2000, All Rights Reserved.