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Omega-3 Fatty Acids Created by: Sarah London, Nutritionist OmegaPure, a division of Omega Protein, Inc Types of Dietary Fat At least one double bond 1 double bond Dietary Fats Unsaturated Fat Fully saturated with hydrogen bonds Saturated Fat More than 2 double bonds Monounsaturated Polyunsaturated Oleic (Olive Oil) Omega-6 Omega-3 • Linoleic • Alpha-Linoleic • Arachiodonic • EPA • GLA • DPA • CLA • DHA Saturated Monounsaturated Peanut oil, coconut Nuts, avocados, tea oil, animal fat, and sea oil, and olive oil butterfat Polyunsaturated Fish, grains such as flaxseed and cereal Trans Partially hydrogenised fats like margarine and baking shortening Imbalance of Omega-6 to Omega-3 in the Western Diet • Current Western Diet 25:1, but could reach 50:1 in individuals consuming mostly processed foods. • Omega-6 promotes inflammation and heart conditions. Paleolithic Diet (1:2) Omega-6 Omega-3 Current Western Diet (25:1) Omega-6 Omega-3 Recommended Diet (4:1) Omega-6 Omega-3 Bourre JM, Dumont O, Piciotti M, Clement M, et al. “Essentiality of n-3 fatty acids for brain structure and function”. World Rev Nutr Diet 66(1991) 103-17; Holub BJ. “Omega-3 fatty acids in cardiovascular care”. CMAJ 166(2002) 608-15 Omega-3 Fatty Acids Contain EPA and DHA that are essential for: • • • • Proper growth and development Metabolic processes Inhibit free forming fatty acids from destroying healthy cells. Allows for better communication between cells. vs. Omega-6 Fatty Acids Omega-6 are involved in: • Production of inflammation • Regulation of cholesterol metabolism • Creates structure in cell membranes Sources: Sources: Fish oil (EPA and DHA), green leafy vegetables and algae (DHA only) Safflower oil, Sunflower oil, Corn oil, Sesame oil, Soybean oil, Wheatgerm oil, Evening Primrose oil, Walnuts Allport, Susan. The Queen of Fats. London: University of California, 2006. Omega-3 Fatty Acids and Cardiovascular Disease USDA “…evidence suggests an association between consumption of fatty acids in fish and reduced risk of mortality from cardiovascular disease for the general population.” 2005 Dietary Guidelines for Americans American Heart Association “Omega-3 fatty acids have been shown in epidemiological and clinical trials to reduce the incidence of cardiovascular disease.” Kris Etherton, P • • Number 1 killer of Americans today 2 out of 5 American deaths caused by cardiovascular disease Kris Etherton, P. et al. Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease. Circulation, 2002; 106:2747. EPA and DHA Recommendations • The US National Institute of Health – 650 mg/day of EPA and DHA and 2 grams/day of omega-3 fatty acids – Limit omega-6 fatty acid to 4 gm/day. Omega-3 fatty acids are long chain polyunsaturated fatty acids and contain the essential nutrients EPA (Eicosapentaenoic Acid) and DHA (Docosahexaenoic Acid). EPA and DHA are essential for: • • • Proper growth and development Metabolic processes Inhibit free forming fatty acids from destroying healthy cells. Types of omega-3 fatty acids: – Alpha linolenic acid (ALA) – Eicosapentaenoic Acid (EPA) – Docosahexaenoic Acid (DHA) – Docosapentaenoic (DPA) The Importance of EPA and DHA DHA EPA Improves blood platelet functionality Reduces inflammation Reduces occurrence of heart attacks Necessary for transport of nutrients through cell membranes Improves blood flow Promotes proper cell turnover Supports healthy development of blood cells Assists in the creation of blood vessels Inhibits free forming fatty acids from destroying healthy cells Fish Oil is the Best Source for Omega- 3 EPA and DHA ALA source (Alpha-Linoleic Acid): • Have to be converted by the body into EPA and DHA • Less than 1% of DHA and EPA from ALA is absorbed due to loss during conversion Algae source: • Algae only contains DHA • Does not contain the essential nutrient EPA Fish oil source: • Contains EPA and DHA • 100% bioavailable- effective immediately for 100% absorption Pawlosky, Robert J. “Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans”. Journal of Lipid Research. 42,(2001): 1257-65 ALA Conversion Process Chloroplast in dark green vegetables, walnuts, and flaxseeds Short chain Supplies ALA Converts to Converts back and forth DHA Converts to EPA Cold water fish, fish oil, free range chicken and eggs, grass fed beef and wild game; fresh seaweed (DHA only) Bioavailable Intermediate Molecules Daily Recommendations for Long Chain Omega-3 Organization Suggested Adult Recommendations (mg) Australia and New Zealand Health Authorities 430mg-610mg/day World Health Organization 1000mg-2000mg/day British Nutrition Foundation 1000mg-2000mg/day American Heart Association 1000mg-4000mg/day Organization Suggested Child Recommendations (mg) Australia and New Zealand Health Authorities 400mg/day World Health Organization Undetermined British Nutrition Foundation Undetermined American Heart Association Undetermined Minimum Recommended: ~500mg/day Typical Omega-3 fatty acid intake in the U.S: 100mg Health Studies Brain Development: IQ, Dyslexia, Dementia, Alzheimer’s, ADD/ADHD, Depression and Suicide, Aggression, Anxiety Neurological: Bi-Polar Disorder, Schizophrenia, Autism, Multiple Sclerosis, Lou Gehrig’s Disease, Parkinson’s Disease Cardiovascular and Circulatory Systems: Atherosclerosis, Triglycerides, Cholesterol, Angina, Heart Attack, Arrhythmias, Stroke, Hypertension, Cardiovascular & Coronary Heart Disease Respiratory System: Asthma, Emphysema, Cystic Fibrosis, ARDS, Chronic Lung Disease, Skeletal and Muscular System: Tooth Loss, Rheumatoid Arthritis, Bone Density, Joint Health, Fibromyalgia Dermatological System: Acne, Eczema, Psoriasis Digestive System: Ulcers, Inflammatory Bowel Disease, Chron’s Disease, Intestinal Disorders Immune System: AIDS, Lupus, Autoimmune Diseases Reproductive System: Prostate Health, Breastfeeding, Pregnancy, Menopause, HPV, PMS Endocrine System: Diabetes Urinary System: Kidney’s, Hemodialysis Cancer: Breast, Prostate, Colorectal, Kidney, Liver, Lymph, Colon, Lung Weight Control Vision: Cataracts, Dry Eye, Macular Degeneration, Retinopathy Scientific Research- Omega-3 and Health This is simply a list of the health benefits associated with EPA and DHA found in fish oil. To learn more about each health concern and the benefits of omega-3, please visit our online library of information of health concerns and discover how omega-3 can create a lifetime of health. www.omegapure.com The excessive consumption of omega-6 fatty acids: • Promote the excessive production of eicosanoids (inflammation) • Increased production of free radicals • Compete with enzymes of metabolic pathways creating a host of medical problems. • Increased susceptibility to lipid oxidation • Stimulates neoplastic cell growth in culture • Impairs insulin activity Why the excess consumption? Food Industry’s Contribution: Consumer barriers to healthy living: • • • • Lack of time Love to eat their favorite foods The expense Confusion with health claims • Not interested in exercise • • • • • Cost Efficient Easier production Shelf stability Longer shelf life Ability to market lowsaturated fat Functional Food Solution • Multiple small changes contribute to significant health rewards • Simple substitutions are key to nutrient dense foods leading to better overall health • Replace your typical product with one enriched with omega-3 Euromonitor International 2007 Maximize Your Health Take an omega-3 supplement Eat more oily fish Reduce omega-6 consumption Restoring Balance • • • • • • • Eat a variety of fruits and vegetables Consume oils with a healthy balance of omega-3 to omega-6 Eat a variety of fatty fish: tuna, salmon, mackerel Eat omega-3 fortified foods Avoid hydrogenated and partially hydrogenated oils- trans fat Choose free range chicken, beef, bison, pork and other wild game Use fish oil supplements rich in EPA and DHA Allport, Susan. The Queen of Fats. London: University of California, 2006. Omega-3 Market Market Evolution Past and Projected Retail Sales of Omega-3 Enhanced Products 2002-2011 7,001.7 $8,000 6,104.4 In Millions 5,499.5 $6,000 4,798.9 3,500.3 $4,000 2,000.2 1,399.7 $2,000 100.0 400.0 820.0 $0 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 Percent increase: 75% * These numbers include flax 37% 15% 11% 15% Source: Packaged Facts: Omega-3 Foods and the U.S. Food and Beverage Market, March 2007 Market Knowledge Types of omega-3 Source Know ledge of Om ega-3 by Consum er Ag e 67% 65% 61% Fish Oil 23% 24% 29% Plant Oil 36-55 years 18-35 years 7% 6% 5% Algae Oil 0% 56 and older 20% 40% 60% 80% Omega Protein, Inc • Omega Protein is the world’s largest processor of fish oil - OmegaPure. • Vertically integrated from catch through production. • Omega Protein owns 40 fishing vessels and 38 spotter planes. • State-of-the-art fish oil refinery produces OmegaPure from herring (menhaden) caught in U.S. waters. • OmegaPure Technology and Innovation Center (OPTIC) established for product development. • Publicly traded on the New York Stock Exchange (OME). For more information on omega-3 fatty acids, EPA/DHA, the industry, or OmegaProtein, please contact me at: 2105 City West Blvd., Suite 500 Houston, Texas 77042-2838 [email protected] Direct Line:713-940-6108