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STEPHANIE D. DAVIS, M.D. Curriculum Vitae Present Positions: Section Director, Pediatric Pulmonology, Allergy and Sleep Medicine James Whitcomb Riley Hospital for Children Indiana University Medical Center Professor of Cellular and Integrative Physiology James Whitcomb Riley Hospital for Children Indiana University Medical Center Present Address: Personal Data: Name: Home Address: Phone Number: Date of Birth: Marital Status: Education: 07/96-06/99 07/94-06/96 07/93-06/94 08/89-05/93 Indiana University School of Medicine James Whitcomb Riley Hospital for Children 705 Riley Hospital Dr. ROC 4270 Indianapolis, IN 46202-5225 (317) 948-7769 Admin. Asst. (317) 944-5791 Fax [email protected] Stephanie Duggins Davis, M.D. 7333 Fox Hollow Ridge Zionsville, IN 46077 317-344-2873 May 10, 1967 Married – Samuel P. Davis, III Profession – Otolaryngology Children – Harrison, Jackson, Parker James Whitcomb Riley Hospital for Children Indiana University Medical Center Director: Howard Eigen, M.D. Fellowship: Pediatric Pulmonary James Whitcomb Riley Hospital for Children Indiana University Medical Center Chairman: Richard Schreiner, M.D. Residency: Pediatrics James Whitcomb Riley Hospital for Children Indiana University Medical Center Chairman: Richard Schreiner, M.D. Internship: Pediatrics Bowman Gray Medical School Wake Forest University 1 08/85-05/89 Winston-Salem, North Carolina Degree: Doctor of Medicine May 17, 1993 University of North Carolina Chapel Hill, North Carolina Degree: Bachelor of Science in Biology May 14, 1989 Professional Experience: 08/2013-present 11/28/11-present Associate Editor, Pediatric Pulmonology Journal Section Director, Pediatric Pulmonology, Allergy and Sleep Medicine James Whitcomb Riley Hospital for Children Indiana University Medical Center Date of Appointment: November 28, 2011 11/28/11-present Professor of Cellular and Integrative Physiology James Whitcomb Riley Hospital for Children Indiana University School of Medicine Date of Appointment: November 28, 2011 2011-present Adjunct Professor of Pediatrics University of North Carolina at Chapel Hill 07/01/09-08/01/11 Division Chief of Pediatric Pulmonology University of North Carolina at Chapel Hill Date of appointment: July 1, 2009 07/01/07-6/30/11 Fellowship Program Director University of North Carolina at Chapel Hill Date of appointment: July 1, 2007 08/15/06-11/23/11 Associate Professor of Pediatrics University of North Carolina at Chapel Hill Date of appointment: August 15, 2006 08/16/99 – 08/14/06 Assistant Professor of Pediatrics University of North Carolina at Chapel Hill Date of appointment: August 16, 1999 Certification and Licensure: A. Certification: Pediatric Pulmonology American Board of Pediatrics National Board of Medical Examiners 2000, recertified in 2007 1996, recertified in 2002 1994 #00610 #058486 #437274 B. Licensure: North Carolina 1999-2012 #9900470 Indiana 1997-1999, 2011-present #01044048 Honors and Awards: 2014-17 Council member for Pulmonology, Society for Pediatric Research 2012 Midwest Society for Pediatric Research 2 2009-2013 2008 2009 2006 1998 1997 Best Doctors Mid-Career Leadership Initiative University of North Carolina at Chapel Hill Academic Leadership Program University of North Carolina at Chapel Hill Society of Pediatric Research University of North Carolina at Chapel Hill Alpha Omega Alpha Indiana University School of Medicine Distinguished Residents and Fellows Asthma Education Scholarship Program; London, England Bibliography: Book Editor: Davis SD, Davis, SD, Koumbourlis A, Eber E, eds. Diagnostic Tests in Pediatric Pulmonology, Springer 2015 Book Chapters: 1. Shapiro AJ, Chilvers MA, Davis SD, Leigh MW. Nasal Nitric Oxide and Ciliary Videomicroscopy: Tests Used for Diagnosing Primary Ciliary Dyskinesia. In: Davis, SD, Koumbourlis A, Eber E, eds. Diagnostic Tests in Pediatric Pulmonology, Springer 2015 2. Kim YJ, Kercsmar C, Davis SD. Fractional Exhaled Nitric Oxide: Indication and Interpretation. In: Davis, SD, Koumbourlis A, Eber E, eds. Diagnostic Tests in Pediatric Pulmonology, Springer 2015 3. Castile RG, Davis, SD. Pulmonary Function Testing in Children. In: Wilmott RW, Bush A, Ratjen F, Deterding R, Boat T, Chernick V, eds. Kendig & Chernick’s Disorders of the Respiratory Tract in Children, 8th edition. 4. Davis SD, Pittman J. Lung Function Testing in Infants. In: Allen JA, Panitch HB, Rubenstein RC, eds. Cystic Fibrosis. New York: Informa Healthcare, 2010; 242: 123147. 5. Davis, SD, Gappa, M, Rosenfeld, M. Respiratory Mechanics. Paediatric Pulmonary Function Testing. In: Hammer J, Eber E, eds. Prog. Respir Res, Basel, Karger, 2005; 33: 20-33. Refereed Articles: 1. Cristea IA, Ackerman V, Swigonski N, Yu Z, Slaven J, Davis SD. “Physiologic Findings in Children Previously Ventilator Dependent at Home due to Bronchopulmonary Dysplasia.” Pediatr Pulmonol ; 2014; in press. 2. Pittman JE, Cutting G, Davis SD, Ferkol T, Boucher R.” Cystic Fibrosis: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.” Annals of the American Thoracic Society, April 2014; 11 (Suppl 3), S161-8 3. Hong Y, Davis B, Marron JS, Kwitt R, Singh N, Kimbell JS, Pitkin E, Superfine R, Davis SD, Zdanski CJ, Niethammer M. “Statistical Atlas Construction via Weighted Functional Boxplots.” Med Image Anal. 2014 March. 4. Brumback LC, Baines A, Ratjen F, Davis SD, Daniel SL, Quittner A, Rosenfeld M. “Pulmonary exacerbations and parent-reported outcomes in children < 6 years with cystic fibrosis.” Pediatr Pulmonol. 2014 March. 3 5. Shapiro AJ, Davis SD, Ferkol T, Dell SD, Rosenfeld M, Olivier KN, Sagel SD, Milla C, Zariwala MA, Wolf W, Carson JL, Hazucha MJ, Burns K, Robinson B, Knowles MR and Leigh MW. “Laterality Defects other than Situs Inversus Totalis in Primary Ciliary Dyskinesia: Insights into Situs Ambiguus and Heterotaxy.” CHEST. 2014 Feb 27. doi: 10.1378/chest.13-1704. [Epub ahead of print] 6. Knowles MR, Ostrowski LE, Leigh MW, Sears PR, Davis SD, Wolf WE, Hazucha MJ, Carson JL, Olivier KN, Sagel SD, Rosenfeld M, Ferkol TW, Dell SD, Milla CE, Randell SH, Yin W, Sannuti A, Metjian HM, Noone PG, Noone PJ, Olson CA, Patrone MV, Dang H, Lee HS, Hurd TW, Gee HY, Otto EA, Halbritter J, Kohl S, Kircher M, Krischer J, Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Zariwala MA. “Mutations in RSPH1 Cause Primary Ciliary Dyskinesia with a Unique Clinical and Ciliary Phenotype.” Am J Respir Crit Care Med. 2014 Feb 25. [Epub ahead of print] 7. Goralski JL, Davis SD. “Challenges and Limitations of Testing Efficacy of Aerosol Device Delivery in Young Children.” J Aerosol Med Pulm Drug Deliv. 2014 Jan 29. [Epub ahead of print] 8. Carpenter DM, Stover A, Slota C, Ayala GX, Yeatts K, Tudor G, Davis S, Williams D, Sleath B. “An evaluation of physicians’ engagement of children with asthma in treatment-related discussions.” J Child Health Care, 2014 18: 216. 9. Leigh MW, Hazucha MJ, Chawla KK, Baker BR, Shapiro AJ, Brown DE, LaVange LM, Horton BJ, Qaqish B, Carson JL, Davis SD, Dell SD, Ferkol TW, Atkinson JJ, Olivier KN, Sagel SD, Rosenfeld M, Milla C, Lee HS, Krischer J, Zariwala MA, Knowles MR; “Standardizing Nasal Nitric Oxide Measurement as a Test for Primary Ciliary Dyskinesia.” Ann Am Thorac Soc 2013; 2013 Dec; 10 (6):574-81. 10. Rosenfeld M, Farrell PM, Kloster M, Swanson JO, Vu T, Brumback L, Acton JD, Castile RG, Colin AA, Conrad CK, Hart MA, Kerby GS, Hiatt PW, Mogayzel PJ, Johnson RC, Davis SD. “Association of Lung Function, Chest Radiographs and Clinical Features in Infants with Cystic Fibrosis.” ERJ; 2013 Dec; 42(6):1545-52. doi:10.1183/ 09031936.00138412. Epub 2013. 11. Davies J, Sheridan H, Bell N, Cunningham S, Davis SD, Elborn JS, Milla CE, Starner TD, Weiner DJ, Lee PS, Ratjen F. “Assessment of clinical response to Ivacaftor with lung clearance index in cystic fibrosis patients with a G551D-CFTR mutation and preserved spirometry: a randomized controlled trial.” Lancet Respir Med. 2013 Oct; 1(8):630-8. doi: 10.1016/S2213-2600(13)70182-6. Epub 2013 Sep 10 12. Knowles MR, Daniels LA, Davis SD, Zariwala MA, Leigh MW; “Primary ciliary dyskinesia. Recent advances in diagnostics, genetics, and characterization of clinical disease.” Am J Resp Crit Care Med; 2013; Oct 15; 188(8):913-22. 13. Austin-Tse C, Halbritter J, Zariwala MA, Gilberti RM, Gee HY, Hellman N, Pathak N, Liu Y, Panizzi JR, Patel-King RS, Tritschler D, Bower R, O'Toole E, Porath JD, Hurd TW, Chaki M, Diaz KA, Kohl S, Lovric S, Hwang DY, Braun DA, Schueler M, Airik R, Otto EA, Leigh MW, Noone PG, Carson JL, Davis SD, Pittman JE, Ferkol TW, Atkinson JJ, Olivier KN, Sagel SD, Dell SD, Rosenfeld M, Milla CE, Loges NT, Omran H, Porter ME, King SM, Knowles MR, Drummond IA, Hildebrandt F. “Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCSC65 Defects as Causing Primary Ciliary Dyskensia.” Am J Hum Genet. 2013 Oct 3; 93(4):672-86. doi: 10.1016/j.ajhg.2013.08.015 4 14. Knowles MR, Ostrowski LE, Loges NT, Hurd T, Leigh MW, Huang L, Wolf WE, Carson JL, Hazucha MJ, Yin W, Davis SD, Dell SD, Ferkol TW, Sagel SD, Olivier KN, Jahnke C, Olbrich H, Werner C, Raidt J, Wallmeier J, Pennekamp P, Dougherty GW, Hjeij R, Gee HY, Otto EA, Halbritter J, Chaki M, Diaz KA, Braun DA, Porath JD, Schueler M, Baktai G, Griese M, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Omran H, Zariwala MA. “Mutations in SPAG1 cause primary ciliary dyskinesia associated with defective outer and inner dynein arms.” Am J Hum Genet. 2013 Oct 3; 93(4):711-20. doi: 10.1016/j.ajhg.2013.07.025. Epub 2013 Sep 19. 15. Calloway HE, Kimbell JS, Davis SD, Retsch-Bogart GZ, Pitkin EA, Abode K, Superfine R, Zdanski CJ; “Comparison of endoscopic versus 3D CT derived airway measurements.” The Laryngoscope; 2013 Sep; 123 (9): 2136-2141. 16. Subbarao P, Stanojevic S, Brown M, Jensen R, Rosenfeld M, Davis S, Brumback L, Gustafsson P, Ratjen F; “Lung Clearance Index as an Outcome Measure for Clinical Trials in Young Children with Cystic Fibrosis: A Pilot Study using Inhaled Hypertonic Saline.” Am J Resp Crit Care Med; 2013; Aug 15; 188(4):456-60. 17. Daniels ML, Leigh MW, Davis SD, Armstrong MC, Carson JL, Hazucha M, Dell SD, Eriksson M, Collins FS, Knowles MR, Zariwala MA; “Founder Mutation in RSPH4A Identified in Patients of Hispanic Descent with Primary Ciliary Dyskinesia.” Hum Mutat. 2013 Jun 24. doi: 10.1002/humu.22371. Epub 2013 Aug 6. 18. Cristea AI, Carroll A, Davis SD, Swigonski N, Ackerman V; “Outcomes of Children with Severe Bronchopulmonary Dysplasia Who Were Ventilator Dependent at Home.” Pediatrics; 2013 Sep; 132(3):e727-34. doi: 10.1542/peds.2012-2990. Epub 2013 Aug 5. 19. Sobush KT, Thornburg CD, Voynow JA, Davis SD, Peterson-Carmichael SL. “A 2-yearold girl with co-inherited cystic fibrosis and sickle cell-β+ thalassemia presenting with recurrent vaso-occlusive events during cystic fibrosis pulmonary exacerbations: a case report.” J Med Case Rep. 2013 Jul 26; 7(1):203. doi: 10.1186/1752-1947-7-203. 20. Sheehan D, Davis SD, Borowitz D. “From Triple Threat to Octopus: Reflections on the Roles of Pediatric Division Chiefs in the Current Era.” Journal of Pediatrics; 2013; Jul; 163(1):4-5. doi: 10.1016/j.jpeds.2013.04.009. 21. Peterson-Carmichael S, Rosenfeld M, Ascher SB, Hornik CP, Arets HGM, Davis SD, Hall G. “Survey of Clinical Infant Lung Function Testing Practices.” Pediatr Pulmonol; 2013 Jun 13. doi: 10.1002/ppul.22807. [Epub ahead of print]. 22. Carpenter DM, Ayala GX, Williams DM, Yeatts KB, Davis SD, Sleath B. “The relationship between patient-provider communication and quality of life for children with asthma and their caregivers.” J Asthma; 2013 Jun 3 Epub 2013 Jul 4. 23. Davis SD, Ferkol T. “Identifying the Origins of Cystic Fibrosis Lung Disease.” N Engl J Med; 2013 May 23;368(21):2026-8 24. Rosenfeld M, Allen J, Arets B, Aurora P, Beydon N, Calogero C, Castile R, Davis SD, Fuchs S, Gappa M, Gustaffson PM, Hall GL, Jones M, Kirkby J, Kraemer R, Lombardi E, Lum S, Mayer H, Merkus P, Nielsen KG, Oliver C, Oostveen E, Ranganathan S, Ren C, Robinson P, Seddon P, Sly P, Sockrider M, Sonnappa S, Stocks J, Subbarao P, Tepper RS, Vilozni D; On Behalf of the American Thoracic Society Ad Hoc Committee; “An Official American Thoracic Society Workshop Report: Optimal Lung Function Tests for Monitoring Cystic Fibrosis, Bronchopulmonary Dysplasia, and Recurrent Wheezing in Children Less than 6 Years of Age.” Ann Am Thoracic Soc; 2013; Apr; 10 (2):S1-S11. doi: 10.1513/ AnnalsATS.201301-017ST. 5 25. Patel K, Davis SD, Johnson R, Esther CR; “Exhaled breath condensate purines correlate with lung function in infants and preschoolers.” Pediatri Pulmonol; 2013 Feb; 48 (2): 182-7. 26. Knowles MR, Leigh MW, Ostrowski LE, Huang L, Carson JL, Hazucha MJ, Yin W, Berg JS, Davis SD, Dell SD, Ferkol TW, Rosenfeld M, Sagel SD, Milla CE, Olivier KN, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Shendure J, Zariwala MA; “Genetic Disorders of Mucociliary Clearance Consortium. Exome sequencing Identifies Mutation in CCDC114 as a Cause of Primary Ciliary Dyskinesia.” Am J Hum Genet. 2013 Jan 10: 92 (1): 99-106. 27. Goralski JL, Lercher D, Davis SD, Dellon E; “Eosinophilic Esophagitis in Cystic Fibrosis: a Case Series and Review of the Literature.” Journal of Cystic Fibrosis; 2013 Jan; 12 (1): 9-14. 28. Brumback LC, Davis SD, Kerby, GS, Kloster MS, Johnson, R, Castile R, Hiatt PW, Hart M, Rosenfeld M; “Lung Function From Infancy to Preschool in a Cohort of Children with Cystic Fibrosis.” European Respiratory Journal; 2013 Jan; 41 1): 60-6. 29. Montgomery G, Davis SD; “Drug therapies to improve mucus clearance in patients with cystic fibrosis.” Current Medical Literature-Cystic Fibrosis; 2012; 2 (4): 85-90. 30. Pittman, JE, Johnson RC, Jones PW, Davis SD; “Variability of a Closed, Rebreathing Setup for Multiple Breath Wash-Out Testing in Children.” Pediatri Pulmonol; 2012 Dec; 47 (12): 1242-50. 31. Sleath B, Carpenter DM, Slota C, Williams D, Tudor G, Yeatts K, Davis S, Ayala GX. “Communication during pediatric asthma visits and self-reported asthma medication adherence.” Pediatrics. 2012 Oct; 130 (4): 627-33. 32. Sleath BL, Carpenter DM, Ayala GX, Williams D, Davis SD, Tudor G, Yeatts K, Gillette C; “Communication during pediatric asthma visit and child asthma medication device technique one month later.” Journal of Asthma; 2012 Nov; 49 (9): 918-25. 33. Kerby GS, Rosenfeld M, Ren CL, Mayer OH, Brumback L, Castile R, Hart MA, Hiatt P, Kloster M, Johnson R, Jones P, Davis SD; “Lung Function Distinguishes Preschool Children with CF from Healthy Controls in a Multi-Center Setting.” Pediatr Pulmonol; 2012 Jun; 47 (6): 597-605. 34. Ren CL, Rosenfeld M, Mayer OH, Davis SD, Kloster M, Castile RG, Hiatt PW, Hart M, Johnson R, Jones P, Brumback LC, Kerby GS; “Lung Function and Clinical Features in Preschool Children with Cystic Fibrosis.” Pediatr Pulmonol; 2012 Jun; 47 (6): 574-81. 35. Rosenfeld M, Ratjen F, Brumback LC, Daniel S, Rowbotham R, McNamara S, Johson R, Kronmal R, Davis SD for the ISIS Study Group; “Inhaled Hypertonic Saline In Infants And Children Less Than Six Year of Age With Cystic Fibrosis: The ISIS Randomized Trial.” JAMA; 2012; May 20:1-9. 36. Knowles M, Leigh M, Carson JL, Davis SD, Dell SD, Ferkol TW, Olivier KN, Sagel SD, Rosenfeld M, Burns KA, Minnix SL, Armstrong MC, Lori A, Hazucha MJ, Loges NT, Olbrich H, Becker-Heck A, Schmidts M, Werner C, Orman H, Zariwala MA; “Genetic Disorders of Mucociliary Clearance Consortium. Mutations of DNAH11 in patients with primary ciliary dyskinesia with normal ciliary ultrastructure.” Thorax; 2012 May; 67 (5): 433-41. 37. Pittman JE, Johnson RC, Davis SD. “Improvement in pulmonary function following antibiotics in infants with cystic fibrosis.” Pediatr Pulmonol. 2012 May; 47 (5): 441-6. 6 38. Washington D, Yeatts K, Sleath B, Ayala GX, Gillette C, Williams D, Davis S, Tudor G. “Communication and education about triggers and environmental control strategies during pediatric asthma visits.” Patient Educ Couns. 2012 Jan; 86 (1): 63-9. 39. Sleath B, Carpenter DM, Sayner R, Ayala GX, Williams D, Davis SD, Tudor G, Yeatts K. “Child and caregiver involvement and shared decision making during asthma pediatric visits.” Journal of Asthma; 2011 Dec; 48 (10): 1022-31. 40. Sleath B, Ayala GX, Washington D, Davis SD, Williams D, Tudor G, Yeatts K, Gillette C. “Caregiver rating of provider participatory decision-making style and caregiver and child satisfaction with pediatric asthma visits.” Patient Educ Couns. 2011 Nov; 85(2): 286-9. 41. Davis SD, Knowles M, Leigh M. “Introduction: primary ciliary dyskinesia and overlapping syndromes.” Proc Am Thorac Soc 2011 Sep; 8(5): 421-2. 42. Ranganathan S, Davis SD, Rosenfeld M. “Clinical Applications of Pediatric Pulmonary Function Testing.” Pediatric Allergy, Immunology, and Pulmonology 2011; September, 24 (3): 133-137. 43. Sagel SD, Davis SD, Campisi P, Dell SD. “Update of Respiratory Tract Disease in Children with Primary Ciliary Dyskinesia.” Proc Am Thorac Soc; 2011 sep; 85): 438-43. 44. Sleath BL, Carpenter DM, Ayala GS, Williams DM, Davis S, Tudor G, Yeatts K, Gillette C. “Provider discussion, education, and question-asking about control medications during pediatric asthma visits.” International Journal of Pediatrics; 2011; 2011: 212160. 45. Rosenfeld M, Davis SD, Brumback L, Daniel S, Rowbotham R, Johnson R, McNamara S, Jensen R, Ratjen F. “Inhaled Hypertonic Saline in Infants and Toddlers with Cystic Fibrosis: Short-Term Tolerability, Adherence and Safety.” Pediatric Pulmonology; 2011, Jul;46(7):666-71 46. Pittman JE, Van Rie A, Davis SD. “Spirometry in Biracial Children: How adequate are race-based reference equations?” Archives of Pediatric Adolescent Medicine; 2011; Jun;165(6):573-4 47. Lesnick BL, Davis SD. “Infant pulmonary function testing: overview of technology and practical considerations--new current procedural terminology codes effective 2010.” Chest; 2011 May; 139(5):1197-202. 48. Gillette CM, Loughlin CE, Sleath BL, Williams DM, Davis SD. “Quality of Pulmonary Function Testing in Three Large Primary Care Pediatric Clinics in Rural North Carolina.” North Carolina Medical Journal; 2011 Mar-Apr; 72(2):105-10. 49. Sleath B, Ayala G, Gillette, C, Williams D, Davis SD, Tudor G, Yeatts K, Washington D. “Provider demonstration and assessment of child asthma device technique during pediatric asthma visits.” Pediatrics; 2011; Apr;127(4):642-8. 50. Olin JT, Burns K, Carson JL, Metjian H, Atkinson JJ, Davis SD, Dell, SD, Ferkol TW, Milla CE, Olivier KN, Rosenfeld M, Baker B, Leigh MW, Knowles MR, Sagel SD for the Genetic Disorders of Mucociliary Clearance Consortium. “Diagnostic Yield of Nasal Scrape Biopsies in Primary Ciliary Dyskinesia: A Multicenter Experience.” Pediatric Pulmonology; 2011 Jan 31; in press. [Epub ahead of print] 51. Pittman J, Calloway E, Kiser M, Yeatts J, Davis SD, Drumm ML, Schechter M, Leigh M, Edmond M, Van Rie A, Knowles M. “Age of Psuedomonas aeruginosa Acquisition and Subsequent Severity of Cystic Fibrosis Lung Disease.” Pediatric Pulmonology; 2010; Dec 30. [Epub ahead of print] 7 52. Davis, SD, Ferkol T. “Hitting the target: new treatments for cystic fibrosis.” Am J Respir Crit Care Med 2010 Dec; in press. 53. Davis SD, Rosenfeld M, Kerby GS, Brumback L, Kloster MH, Acton JD, Colin AA, Conrad CK, Hart MA, Hiatt PW, Mogayzel PJ, Johnson RC, Wilcox SL, Castile RG. “Multicenter Evaluation of Infant Lung Function Tests as Cystic Fibrosis Clinical Trial Endpoints.” Am J Respir Crit Care Med 2010 Dec; in press. 54. Sleath B, Ayala G, Davis S, Williams D, Tudor G, Yeatts K, Washington D, Gillette C. “Child and caregiver reported problems and concerns in using asthma medications.” Journal of Asthma; 2010 Aug; 47 (6): 633-8. 55. Borowitz D, Parad RB, Sharp JK, Sabadosa KA, Robinson KA, Rock MJ, Farrell PM, Sontag MK, Rosenfeld M, Davis SD, Marshall BC, Accurso FJ. “Cystic Fibrosis Foundation Practice Guidelines for the Management of Infants with Cystic Fibrosis Transmembrane Conductance Regulator-Related Metabolic Syndrome During the First Two Years of Life and Beyond.” J Pediatr 2009 Dec;155:S106-16. 56. Borowitz D, Robinson KA, Rosenfeld M, Davis SD, Sabadosa KA, Spear SL, Michel SH, Parad RB, White TB, Farrell PM, Marshall BC, Accurso FJ. “Cystic Fibrosis Foundation Evidence-Based Guidelines for Management of Infants with Cystic Fibrosis.” J Pediatr 2009 Dec;155:S73-93. 57. Stanojevic S, Wade A, Cole TJ, Lum S, Custovic A, Silverman M, Hall GL, Welsh L, Kirkby J, Nystad W, Badier M, Davis SD, Turner S, Piccioni P, Vilozni D, Eigen H, Vlachos-Mayer H, Zheng J, Tomalak W, Jones M, Hankinson JL, Stocks J. “Spirometry Centile Charts for Young Caucasian Children: The Asthma UK Collaborative Initiative.” Am J Respir Crit Care Med 2009; Sep 15;180(6):547-52 58. Leigh MW, Pittman JE, Carson JL, Ferkol TW, Dell SD, Davis SD, Knowles MR, Zariwala MA. “Clinical and Genetic Aspects of Primary Ciliary Dyskinesia/Kartagener Syndrome.” Genetics in Medicine 2009, Jul 11 (7): 473-87. 59. Peterson-Carmichael S, Harris WT, Goel R, Noah TL, Johnson R, Leigh M, Davis SD. “The Association of Lower Airway Inflammation with Physiologic Findings in Young Children with Cystic Fibrosis.” Pediatric Pulmonology 2009 May; 44(5):503-11. 60. Dellon EP, Donaldson SH, Johnson R, Davis SD; “Safety and Tolerability of Inhaled Hypertonic Saline in Young Children with Cystic Fibrosis.” Pediatr Pulmonol. 2008; Nov; 43(11):1100-6. 61. Davis SD, Aurora P, Eigen H, Beydon N, Lombardi E on behalf of the ATS/ERS Working Group on Infant and Young Children Pulmonary Function Testing. “Quality Control for Spirometry in Preschool Children (author correspondence).” Am. J. Respir. Crit. Care Med., Jul 2008; 178: 107 - 108 62. Davis SD, Johnson RC, Flucke RL, Kisling JA, Myers TR. “AARC Clinical Practice Guideline: Infant/Toddler Pulmonary Function Tests.” Respiratory Care. 2008 Jul; 53 (7): 929-945. 63. Davis SD, Ratjen F. “Reduced Lung Function in Cystic Fibrosis: A primary or secondary phenotype?” (editorial); Am J Respir Crit Care Med 2008 Jul 1; 178 (1): 2-3 64. Brown DE, Pittman JE, Leigh MW, Fordham L, Davis SD. “Early Lung Disease in Young Children with Primary Ciliary Dyskinesia.” Pediatr Pulmonol. 2008 May; 43(5):514-6. 8 65. Esther CR, Alexis NE, Clas ML, Lazarowski ER, Donaldson SH, Pedrosa Ribeiro CM, Moore CG, Davis SD, Boucher RC. “Extracellular Purines are Biomarkers of Neutrophilic Airway Inflammation.” Eur Respir J. 2008 May;31(5):949-56. 66. Davis SD, Brody AS, Emond MJ, Brumback LC, Rosenfeld M. “Endpoints for Clinical Trials in Young Children with Cystic Fibrosis.” Proceedings of the American Thoracic Society 2007; Aug 1;4(4):418-30. 67. Beydon N; Davis SD; Lombardi E; Allen JL, Arets HGM, Aurora P, Bisgaard H, Davis GM, Ducharme F, Eigen H, Gappa M, Gaultier C, Gustafsson PM, Hall GL, Hantos Z, Healy MJR, Jones MH, Klug B, Lodrup Carsen KC, McKenzie SA, Marchal F, Mayer OH, Merkus PJFM, Morris MG, Oostveen E, Pillow JJ, Seddon PC, Silverman M, Sly PD, Stocks J, Tepper RS, Vilozni D, Wilson NM, on behalf of the ATS/ERS Working Group on Infant and Young Children Pulmonary Function Testing. “An Official American Thoracic Society/European Respiratory Society Statement: Pulmonary Function Testing in Preschool Children.” Am J Respir Crit Care Med 2007 Jun 15; 175: 1305-1345. 68. Davis, SD, Fordham, LA, Noah, TL, Retsch-Bogart, GZ, Qaqish, B, Yankaskas, BC, Johnson, RC, Leigh, MW. “HRCT abnormalities reflect BALF inflammation and track changes in early CF.” Am J. Respir Crit. Care Med 2007; 175(9):943-50. 69. Saito J, Harris T, Gelfond J, Noah T, Leigh M, Johnson R, Davis SD. “Physiologic, Bronchoscopic and Bronchoalveolar Lavage Fluid Findings in Young Children with Recurrent Wheeze and Cough.” Pediatr Pulmonol. 2006 Aug; 41: 709-719. 70. The ATS/ERS Working Group on Infant and Young Children Pulmonary Function Testing Consensus Statement. (Member). “Raised volume forced expirations in infants: guidelines for current practice.” Am J Respir Crit Care Med. 2005 Dec; 172: 1463-1471. 71. Jones M, Howard J, Davis SD, Kisling J, Tepper R. “Sensitivity of Spirometric Measurements to Detect Airway Obstruction in Infants.” Am. J. Respir. Crit. Care Med. 2003 May; 167: 1283-1286. 72. Goldstein A, Castile R, Davis SD, Filbrun D, Flucke R, McCoy K, Tepper R. “Bronchodilator Responsiveness in Normal Infants and Young Children.” Am J Respir Crit Care Med. 2001 Aug; 164: 447-454. 73. Davis S, Jones M, Kisling J, Howard J, Tepper R. “Comparison of normal infants and infants with cystic fibrosis using forced expiratory flows breathing air and heliox.” Pediatr Pulmonol. 2001 Jan; 31(1): 17-23. 74. Jones M, Davis SD, Kisling J, Howard J, Castile R, Tepper R. “Flow Limitation in Infants Assessed by Negative Expiratory Pressure.” Am J Respir Crit Care Med. 2000 Mar; 161: 713-717. 75. Jones M, Castile R, Davis SD, Kisling J, Filbrun D, Flucke R, Goldstein A, Emsley C, Ambrosius W, Tepper R. “Forced Expiratory Flows and Volumes in Infants: Normative Data and Lung Growth.” Am J Respir Crit Care Med. 2000 Feb; 161: 353-359. 76. Davis SD, Jones M, Kisling J, Castile R, Tepper R. “Density Dependence of Forced Expiratory Flows in Healthy Infants and Toddlers.” J Appl. Physiol. 1999 Nov; 87(5): 1796 - 1801. 77. Tepper RS, Jones M, Davis SD, Kisling J, and Castile R. “Rate Constant for Forced Expiration Decreases with Lung Growth during Infancy.” Am J Respir Crit Care Med. 1999 Sep; 160: 835-838. 9 78. Jones MH, Davis SD, Grant D, Christoph K, Kisling J, Tepper RS. “Forced Expiratory Maneuvers in Very Young Children Assessment of Flow Limitation.” Am J Respir Crit Care Med. 1999 Mar;159:791-795. 79. Davis SD, Jones M, Kisling J, Angelicchio C, Tepper RS. “Effect of Continuous Positive Airway Pressure on Forced Expiratory Flows in Infants with Tracheomalacia.” Am J Respir Crit Care Med. 1998; 158:148-152. Review Articles: 1. Goralski J, Davis SD. “Breathing Easier: Addressing the Challenges of Aerosolizing Medications to Infants and Preschoolers” Respiratory Medicine. 2014 2. Davis, SD. “CON: HRCT should be a routine part of CF lung disease assessment.” Pediatr Pulmonol. 2010. 3. Davis SD, Pittman J. “Measurement of Early Lung Disease in Children with Cystic Fibrosis.” eCysticFibrosis Review January 2009 Volume 1, Issue 5. 4. Davis SD, Rosenfeld M. “Using Diagnostic Tools in the Young Child: X-rays and Pulmonary Function.” Pediatr Pulmonol. 2007, Suppl 30. 5. Dellon E, Davis SD. “Catch Me If You Can.” ADVANCE for Managers of Respiratory Care. 2007; 16 (6): 34. 6. Peterson-Carmichael, S, Davis S. “Debunking the Myth.” ADVANCE for Managers of Respiratory Care. 2007; 16(1): 63. 7. Rosenfeld M, Davis SD. “Infant Pulmonary Function Tests as Outcome Measures for Clinical Trials.” Pediatr Pulmonol. 2006; Suppl 29: S18.2. 8. Davis, S. “Preschool Spirometry.” Pediatric Respiratory Review, 2006, 7S, S11-S13. 9. Davis, S. “Neonatal and Pediatric Respiratory Diagnostics.” Respiratory Care, 2003; 48(4): 367-385. 10. Davis S. “Clinical Utility of Heliox.” ADVANCE for Managers of Respiratory Care. 2000; 9(5): 52-56. Editor of Series of Articles in Journal: 1. Primary Ciliary Dyskinesia and Overlapping Syndromes: series of 5 manuscripts submitted to Proceedings of the American Thoracic Society; served as 1 of the 3 editors 2. Guidelines for Preschool Lung Function Testing: Series of 8 papers submitted as one large manuscript to Am J Respir Crit Care Med (Refereed article 4): Lung Function Testing in Preschool Children: The Next Frontier Clinical Implications of Pulmonary Function Testing in Preschool Children The Interrupter Technique in Preschool Children The Forced Oscillation Technique in Preschool Children Assessment of Tidal Breathing Parameters in Preschool Children Preschool Spirometry Guidelines The Multiple Breath Inert Gas Washout (MBW) Technique in Preschool Children Bronchial Responsiveness Tests in Preschool Children 10 Refereed Abstracts: 1. Herrera-Camino A, Stevens J, Bendy LL, Yu Z, Slaven J, Tepper RS, Davis SD; “Association Between Sugar Cane Burning and the Prevalence of Asthma, Atopy, and Pulmonary Function Changes in Rural Honduran Children” Annals of ATS; 2014, abstracts issue. 2. Assaf S, Clem C, Westerhold JR, Tepper RS, Davis SD, “Ventilation Inhomogeneity in Children with Asthma.” Annals of ATS; 2014, abstracts issue. 3. Krupp NL, Fiscus C, Krespach M, Davis SD, “Improvement of 30 Day Asthma Readmission Rate Through Comprehensive Coordinated Quality Improvement.” Annals of ATS; 2014, abstracts issue 4. Cristea IC, Jalou H, Ackerman V, Davis SD, Givan DC, “Use of Polysomonography to Assess Safe Decannulation in Children.” Annals of ATS; 2014, abstracts issue 5. Deschamp A, Pettit R, Howenstine M, Slaven J, Donaldson J, Yu Z, Davis SD, “Efficacy and Safety of Intravenous (IV) Aminoglycoside Dosing Intervals in the Pediatric Cystic Fibrosis Population.” Pediatr Pulmonol; 2013; Volume 48, Issue S36. 6. Donaldson SD, Samulski D, LaFave C, Wu J, Zeman K, Salazar C, Bennett WD, Davis SD. “Sustained Effect of Hypertonic Saline on Mucociliary Clearance in CF Children with Mild Lung Disease.”Pediatr Pulmonol; 2013; Volume 48, Issue S36. 7. Kimbell JS, Fleischman GM, Pitkin E, Davis SD, Zdanski C. “Wall Shear Stresses and Airflow Patterns in the Upper Airway of a Child with Subglottic Stenosis: Comparisons Before and After Airway Reconstruction with Normal Children.” Annals of ATS; 2014 8. Zariwala MA, Ostrowski LE, Loges NT, Hurd T, Leigh MW, Huang L, Wolf WE, Carson JL, Hazucha MJ, Yin W, Davis SD, Dell SD, Ferkol TW, Sagel SD, Olivier KN, Jahnke C, Olbrich H, Werner C, Gee HY, Otto EA, Halbritter J, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Omran H, Knowles MR. “Exome Sequencing Identifies Germline Mutations in SPAG1 as a Cause of Primary Ciliary Dyskinesia Associated with Defective Outer and Inner Dynein Arms.” Ann Am Thoracic Soc; 2013; in press 9. Hong Y, Neithammer M, Andruejol J, Kimbell JS Pitkin E, Superfine R, Davis SD, Zdanski C, Davis BC. “A Pediatric Airway Atlas and Its Application in Upper Airway Obstruction.” Ann Am Thoracic Soc; 2013; A3684. 10. Zariwala MA, Daniels ML, Leigh MW, Davis SD, Armstrong MC, Carson JL, Hazucha M, Dell SS, Eriksson M, Collins FS, and Knowles MR. “Founder Mutation in RSPH4A Gene Identified in Patients of Hispanic Descent with Primary Ciliary Dyskinesia.” Gordon Research Conference: Cilia, Mucus & Mucociliary Interactions, April 7-12, 2013; Lucca (Barga) Italy. 11. Leigh MW, Chawla KK, Baker BR, Hazucha MJ, Brown DE, LaVAnge LM, Horton BJ, Qaqish BF, Caron JL, Davis SD, Dell SD, Ferkol TW, Atkinson JJ, Olivier KN, Sagel SD, Rosenfeld M, Milla C, Zariwala MA, Knowles MR and Genetic Disease of Mucociliary Clearance Consortium (GDMCC). “Standardization of Nasal Nitric Oxide as Screening Test for Primary Ciliary Dyskinesia.” Am J Respir Crit Care Med; 2012 185: A3898 12. Leigh MW, Shapiro AJ, Pittman JE, Davis SD, Lee H, Krischer J, Ferkol TW, Atkinson JJ, Sagel SD, Rosenfeld M, Dell SD, Milla C, Olivier KN, Knowles MR and Genetic Disease of Mucociliary Clearance Consortium (GDMCC). “Definition of Clinical Criteria 11 for Diagnosis of Primary Ciliary Dyskinesia.” Am J Respir Crit Care Med; 2012 185: A2483 13. Pittman JE, Lin F, Johnson R, Jones P, Davis SD. “Patterns of Infant Lung Function in Infants with Cystic Fibrosis vs. Wheezy Infants.” Am J Respir Crit Care Med; 2012 185: A5262. 14. Stanojevic S, Gappa M, Davis SD, Kirky J, Stocks J, Hall G. “Re-Defining Quality Control Criteria for Spirometry in Young Children.” Am J Respir Crit Care Med; 2012 185: A2352. 15. Pittman JE, Lin F, Davis S. “Population Characteristics of Young School-Age Children with CF.” Pediatric Pulmonology 46; Issue S34 (abstracts issue) September 2011. 16. Pittman JE, Noah HH, Calloway EH, Davis SD, Sagel SD, Accurso FJ, Knowles MR, Sontag MK. “Early Infection with Pseudomonas aeruginosa Does Not Explain Differences in Lung Function in Early Childhood That Persist into Adolescence in Subjects with Cystic Fibrosis: A Replication Study.” Am J Respir Crit Care Med. 2011 (abstracts issue); in press 17. Pittman JE, LaFave CO, Coverstone A, Johnson RC, Jones P, Davis SD. “Lung Function in Children of All Races Correlates Well with Surrogate Measures of Thorax Length.” Am J Respir Crit Care Med. 2011 (abstracts issue); in press 18. Pittman JE, Rosenfeld M, LaFave C, Ferkol T, Sagel S, Dell S, Milla CE, Jones P, Johnson RC, Leigh MW, Knowles MR, Davis SD, on behalf of the Genetic Diseases of Mucociliary Clearance Consortium. “Characteristics of Primary Ciliary Dyskinesia in Children Under 5 Years of Age.” Am J Respir Crit Care Med. 2011 (abstracts issue); in press 19. Pittman JE, Johnson RC, Jones P, Davis SD. “Multiple Breath Washout using a Closed (Rebreathing) System in Children with Cystic Fibrosis vs. Healthy Controls – Initial Results.” Am J Respir Crit Care Med. 2011 (abstracts issue); in press 20. Pittman JE, Zariwala M, Weck K, Leigh MW, Davis SD. “Respiratory Failure as Cause of Death in an Infant with Primary Ciliary Dyskinesia.” Am J Respir Crit Care Med. 2011 (abstracts issue); in press. 21. Rosenfeld M, Davis S, Ice C, Johnson C, Oermann C, Prestridge A, Sawicki G, VirellaLowell I, Wilmott R. “Tolerability Of Denufosol For Inhalation In 2 to 4 Year Old Children with Cystic Fibrosis.” Pediatric Pulmonology 46; Issue S34 (abstracts issue) September 2011 22. Rosenfeld M, Farrell PM, Kloster M, Brumback L, Acton J, Colin A, Conrad C, Hart M, Kerby G, Hiatt P, Mogayzel P, Johnson R, Castile R, Davis SD. “Association of Physiologic Measures and Clinical Characteristics in a Multicenter Cohort of Infants with CF.” Pediatric Pulmonology 46; Issue S34 (abstracts issue) September 2011. 23. Brumback LC, Davis SD, Kerby GS, Kloster M, Johnson R, Castile R, Hiatt PW, Rosenfeld M. “Lung Function from Infancy through Preschool in a Cohort of Children with CF.” Pediatric Pulmonology; Supp 33 (abstract issues), October 2010. 24. Ren CL, Kerby GS, Rosenfeld M, Mayer OH, Castile R, Hart M, Hiatt PW, Kloster M, Brumback LC, Johnson R, Davis SD. “Analysis of the Association between Clinical Features and Lung Function in Preschool Children with CF.” Pediatric Pulmonology; Supp 33 (abstract issues), October 2010. 12 25. Chawla K, Hazucha MJ, Dell SD, Ferkol TW, Sagel SD, Rosenfeld M, Baker B, Davis SD, Knowles MR, Leigh MW. Genetic Diseases of Mucociliary Clearance Consortium. Am J Respir Crit Care Med., 2010; 181:A6726. 26. Pittman JE, Johnson RC, Davis SD. Bronchodilator Responsiveness by Infant Pulmonary Function Testing. Am J Respir Crit Care Med., 2010; 181:A3916 27. Shapiro AJ, Davis SD, Olivier KN, Ferkol TW, Dell SD, Sagel SD, Rosenfeld M, Milla CE, Atkinson JJ, Knowles MR, Leigh MW. Clinical Symptoms Associated with Primary Ciliary Dyskinesia – Results of a Multi-Centered Study. Am J Respir Crit Care Med., 2010; 181:A6728. 28. Patel KA, Davis SD, Johnson R, Esther CR. Disease Markers in the Exhaled Breath Condensate of Infants and Preschoolers. Am J Respir Crit Care Med., 2010; 181:A3288. 29. Peterson-Carmichael SL, Johnson R, Noah TL, Davis SD. Physiologic and Inflammatory Findings in Young Children After Respiratory Syncytial Virus (RSV) Bronchiolitis. Am J Respir Crit Care Med., 2010; 181:A3293. 30. Ramanathan C, Davis S, Alexis N, Leigh M, Boucher R, Donaldson S. Evaluation of Percent Solids of Lower Airway Secretions of Infants and Children with Cystic Fibrosis. Ped Pulm Supp. 32 (abstracts issue) October 2009. 31. Pittman J, Johnson R, Davis S. Change in Pulmonary Function Following IV Antibiotics in Infants with CF. Ped Pulm Supp. 32 (abstracts issue) October 2009. 32. Pittman J, Johnson R, Davis S. Bronchodilator Responsiveness in Infants with CF. Ped Pulm Supp. 32 (abstracts issue) October 2009. 33. Kerby GS, Rosenfeld M, Ren CL, Mayer OH, Castile R, Hart M, Hiatt PW, Kloster M, Brumback L, Johnson R, Davis SD. Spirometry Distinguishes Preschool Children with CF From Healthy Controls in a Multicenter Setting. Ped Pulm Supp. 32 (abstracts issue) October 2009. 34. Leigh MW, Ferkol TW, Dell SD, Davis SD, Knowles MR. Primary Ciliary Dyskinesia in Children: Dichotomy in Structural Versus Functional Changes in Airways. Am. J. Respir. Crit. Care Med., Apr 2009; 179: A3674. 35. Pittman JE, Davis SD. Spirometry in Biracial Children: Assessing Adequacy of Current Race-Based Reference Equations. Am. J. Respir. Crit. Care Med., Apr 2009; 179: A4850. 36. Kerby GS, Rosenfeld M, Ren C, Mayer O, Castile R, Hart M, Hiatt P, Kloster M, Brumback L, Johnson R, Davis SD. Multi-center lung function testing in preschool subjects; Ped Pulm Supp. 31 (abstracts issue) October 2008 37. Rosenfeld M, Davis SD, Brumback L, Daniel S, Johnson R, Rowbotham R, McNamara S, Martin S, Barlow C, Ratjen F. Inhaled 7% Hypertonic Saline is Well Tolerated in Infants and Toddlers with CF. Ped Pulm Supp. 31 (abstracts issue) October 2008. 38. Pittman J, Calloway E, Yeatts J, Drumm M, Leigh M, Davis S, Van Rie A, Emond M, Knowles M. Age of Pseudomonas aeruginosa Infection and Severity of Lung Disease in Cystic Fibrosis Adolescents and Adults. Ped Pulm Supp. 31 (abstracts issue) October 2008: A332, p. 319. 39. Ayala GX, Sleath B, Davis S, Williams D, Yeatts K, Washington D; Child and caregiver question-asking and input into asthma management regimens during pediatric visits; International Conference on Communication in Healthcare; Oslo, Norway 40. Sleath B, Ayala GX, Williams D, Davis S, Yeatts K, Washington D; Provider question asking about asthma controller medications during pediatric asthma visits; International Conference on Communication in Healthcare; Oslo, Norway 13 41. Huda W, Fordham LA, Frey GD, Davis S; Effective Doses to Pediatric Cystic Fibrosis Patients Undergoing Chest CT Examinations. American Association of Physicists in Medicine, July 27-31, 2008 42. Pittman JE, Davis SD, Chawla KK, Brown DE, Knowles MR, Leigh MW. Primary Ciliary Dyskinesia: Characteristics of Children under Six. Proceedings of the American Thoracic Society; 2008, A798. 43. Dellon E, Donalson S, Johnson R, Davis S; Safety and Tolerability of Hypertonic Saline in Infants and Young Children with Cystic Fibrosis; Pediatric Pulmonology, 2007, Suppl 30; 298. 44. Davis, S, Kerby, G, Acton, J, Castile, R, Colin, A, Conrad, C, Hart, M, Hiatt, P, Mogayzel, P, Johnson, R, Wilcox, S, Knutzen, S, Brumback, L, Rosenfeld, M. Feasibility, Sensitivity and Variability of Adult-Type Pulmonary Function Tests in Infants with CF in a Multicenter, Longitudinal Trial; Pediatric Pulmonology, 2006, Suppl 29; 360. 45. Dellon E, Donalson S, Johnson R, Davis S; Safety and Tolerability of Hypertonic Saline in Young Children with Cystic Fibrosis; Pediatric Pulmonology, 2006, Suppl 29; 283. 46. Rosenfeld M, Brumback L, Knutzen S, Acton J, Castile R, Colin A, Conrad C, Hart M, Hiatt P, Kerby G, Mogayzel P, Johnson R, Wilcox S, Davis SD. Multicenter Longitudinal Evaluation of Raised Volume Forced Expiratory Flows in Infants with CF is Feasible; PediatricPulmonology, 2005, Suppl 28; 354. 47. Davis SD, Peterson-Carmichael S, Noah T, Johnson R, Abode K, Leigh M. Correlation of Infant Lung Function and Bronchoalveolar Lavage Fluid (BALF) Data in CF Infants; Pediatric Pulmonology, 2005, Suppl 28; 336. 48. Davis SD, Kerby G, Acton J, Castile R, Colin A, Conrad C, Hart M, Hiatt P, Mogayzel P, Brumback L, Johnson R, Wilcox S, Wohl ME, Rosenfeld M. Creating an Infant Lung Function Testing Network. Pediatric Pulmonology, 2004, Suppl 27; 329. 49. Davis SD, Fordham LA, Noah TL, Retsch-Bogart GZ, Qaqish B, Yankaskas BC, Johnson RC, Leigh MW. HRCT abnormalities reflect BALF inflammation and track changes in early CF. Pediatric Pulmonology, 2004, Suppl 27; 328. 50. Saito J, Johnson R, Noah T, Leigh M, Davis S. Correlation of Physiologic Markers versus Flexible bronchoscopy Findings in Infants with Recurrent Wheeze and Cough. Am J Respir Crit Care Med. 2004; 164 (7): A489 51. Davis SD, Fordham LA, Retsch-Bogart G, Noah T, Johnson R, Abode K, Leigh M. Detecting and Tracking CF Lung Disease using HRCT and BAL in Infants. Pediatric Pulmonology, 2002; Suppl 24: A 374. 52. Harris W, Wood R, Davis S, Retsch-Bogart G, Leigh M. Chronic/Recurrent Wheezing In Infants And Young Children: A Bronchoscopic Study. Pediatric Research, 2000. 47: 477A 53. Tepper RS, Davis S, Jones M, Kisling J, Payne N. Changes In Full Forced Expiratory Flow Volume Maneuvers During Bronchial Challenge Testing In Infants. Eur Respir J 1999. 54. Goldstein A, Castile R, Davis S, Filbrun D, Flucke R, Tepper R, McCoy K. Bronchodilator Responsiveness in Infants with Cystic Fibrosis. Peds Pulmon Suppl 19: 279, 1999. 14 55. Goldstein A, Castile R, Davis S, Filbrun D, Flucke R, McCoy K, Tepper R. Bronchodilator Responsiveness in Normal Infants. Am J Respir Crit Care Med. 1999;195(3)pt2: A674. 56. Davis S, Jones M, Kisling J, Howard J, Tepper RS. Comparison of normal and cystic fibrosis (CF) infants using forced expiratory flows breathing heliox. Am J Respir Crit Care Med. 1999;159(3)pt2:A504. 57. Jones M, Castile R, Davis S, Goldstein A, Filbrun D, Kisling J, Fluck R, Tepper R. Forced expiratory maneuvers in normal infants: normative values. Am J Respir Crit Care Med. 1999;159(3)pt2:A504. 58. Tepper RS, Jones M, Davis S, Kisling J, Howard J, Castile R. The Time Constant from Forced Expiratory Flow Volume Curves Increases with Lung Growth During Infancy. EurRespir J. 1998;12(28):155(#0204). 59. Davis S, Jones M, Kisling J, Castile R, Tepper RS. Density Dependence of Forced Expiratory Flows in Healthy Infants. Am J Respir Crit Care Med. 1998;157(3):A470. 60. Jones M, Davis S, Kisling J, Castile R, Tepper RS. Negative Expiratory Pressure to Assess Flow Limitation in Infants. Am J Respir Crit Care Med. 1998;157(3):A471. 61. Tepper RS, Davis S, Jones M, Kisling J. The Effect of CPAP on Forced Expiratory Flows in Healthy Infants. Eur Respir J. 1997; 10(25):167s(#1148). 62. Jones M, Davis S, Grant D, Christoph K, Tepper RS. Negative Pressure to Assess Flow Limitation in Very Young Children. Am J Respir Crit Care Med. 1997;155(4)pt2:A376. 63. Davis S, Jones M, Kisling J, Angelicchio C, Tepper RS. “Effect of Continuous Positive Airway Pressure (CPAP) on Forced Expiratory Flows of Infants with Tracheomalacia. Am J Respir Crit Care Med. 1997;155(4)pt2:A376. Invited Workshops: 1. NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases; September 2013 2. NHLBI Workshop: Developmental Pathways in Lung Disease; June 28-29 2012European Respiratory Society: Preparing for the first early pulmonary intervention studies in infants and preschool children with Cystic Fibrosis; March 2012 3. NHLBI Working Group on Data Coordinating Centers’ Best Practices; May 2011; http://www.nhlbi.nih.gov/meetings/workshops/dcc.htm 4. European Cystic Fibrosis Society – Clinical Trials Network Consensus Conference on Outcome Parameters in Cystic Fibrosis; March 2010; Venice, Italy. 5. Advancing Rare Diseases Research though Networks and Collaboration; July 2009; National Institute of Health 6. Care of Patients with CF Diagnosed by Newborn Screening; July 2007; Cystic Fibrosis Foundation 7. Preventing Respiratory Sequelae in Children Diagnosed with Cystic Fibrosis by Newborn Screening; February 2007; European Respiratory Society; Belgium 8. Imaging Endpoints for Cystic Fibrosis Clinical Trials; September 2005. 9. HRCT Special Interest Group Conference; October 2003; North American Cystic Fibrosis Conference 15 Teaching Record: National/International: 2014 2014 2013 2013 2013 2013 2012 2012 2012 2012 2012 2012 2012 2012 2012 2012 2012 Speaker, Year in Review, American Thoracic Society Conference Cystic Fibrosis Speaker, American Thoracic Society Faculty Development Series Panel Discussion Chair, Poster Discussion Session, American Thoracic Society Conference Tools of the Trade: Modalities for Evaluating Pediatric Lung Disease Session Chair, Scientific Symposium, American Thoracic Society Conference Applying Novel Models and Mechanistic Approaches to Pediatric Respiratory Disease Speaker and Moderator, American Thoracic Society Annual Conference Lecture: Detecting Early Lung Disease in Cystic Fibrosis: What Works? Speaker, International Society for Aerosols in Medicine Lecture: Challenges and Limitations for Testing Efficacy of New Aerosol Therapies in Young Children Schwartz Lecturer, University of Rochester, Lecture: Using Physiologic and Structural Endpoints to Assess Respiratory Disease in Young Children Invited Speaker, CHEST Lecture: Cystic Fibrosis: The Year in Review Speaker, U.S. Congressional Briefing Presentation Briefing: Advances & Opportunities in Child Lung Health 26th Annual North American Cystic Fibrosis Conference Evening Symposium Lecture: Ahead of the Curve Early Intervention in CF-Assessment of Early Lung Disease Speaker and Moderator, 26th Annual North American Cystic Fibrosis Conference Lecture: Lung Function Testing in the Youngest Population Visiting SMURRF Professor, Cincinnati Children’s Hospital Medical Center Lecture: Choosing the Road Less Traveled: Pursuing a Career as a Pediatric Physician-Scientist Facilitator, American Thoracic Society Annual Conference Poster Discussion: Pediatric Cystic Fibrosis and Primary Ciliary Dyskinesia Speaker, American Thoracic Society Annual Conference NIH Noon Workshop, Infant PFTs as an Endpoint in the Infant Study of Inhaled Saline Trial Speaker and Moderator, American Thoracic Society Annual Conference Postgraduate course, Complications of Cystic Fibrosis Chair, Pediatric Academic Society Original Science Abstracts Platform Session: Asthma Invited Speaker, Vanderbilt University Pediatric Grand Rounds Lecture: The Changing Face of Cystic Fibrosis 16 2011 2011 2011 2011 2011 2011 2011 2011 2011 2010 2010 2010 2010 2010 Invited Speaker, CHEST Lecture: Determining the Etiology of Non-CF Bronchiectasis Invited Speaker, CHEST Lecture: New Diagnostics Tools in PCD: Nasal NO, Infant PFTs, Genetic Analysis, and High Speed Video Light Microscopy Invited Speaker, CHEST Pediatric Fellows Conference Lecture: Infant PFTS Panel Member and Speaker, The Multidisciplinary Airway Team Approach to Challenging Pediatric Patients NC/SC Otolaryngology & Head & Neck Surgery Annual Meeting Invited Speaker, PCD Complications in Newborns and Very Young Children 9th Annual PCD Family day Symposium, American Thoracic Society Annual Conference Moderator, Pediatric Year in Review Symposium, American Thoracic Society Annual Conference Moderator and Speaker, Functional Modeling of the Pediatric Upper Airway Speaker, American Thoracic Society Annual Conference Postgraduate course, Applied Pulmonary Physiology in the Infant PFT Lab Moderator, American Thoracic Society Annual Conference Postgraduate course: Diagnostic Tests for the Pediatric Pulmonologist Invited Speaker, Pro-Con Debates in CF Lung Disease: MRSA, Chest CT & Pulmonary Maintenance Therapies (Symposium) High Resolution CT Scans of the Chest Should be a Routine Part of CF Lung Disease Assessment: Con Speaker, Primary Ciliary Dyskinesia and Overlapping Syndromes Early lung disease in young children with PCD Chairman/Speaker, American Thoracic Society Annual Conference Mini-Symposium: Inspiring the Next Generation of Pediatric Pulmonary Researchers Chairman/Speaker, American Thoracic Society Annual Conference Postgraduate Course: Airway Resistance: Theory and Practice Speaker, American Thoracic Society Annual Conference Postgraduate Course: How Should We Assess Outcomes in CF? 17 2009 2009 2009 2008 2008 2008 2008 2008 2007 2007 2007 2007 2007 2007 2006 2006 2006 2006 2006 2006 2006 2005 2005 Featured Speaker, American Thoracic Society Annual Conference Lecture: The Value of Monitoring Lung Function throughout the Pediatric Age Moderator, American Thoracic Society Annual Conference Mini-Symposium: Best of Pediatrics Invited Speaker, Cystic Fibrosis Therapeutic Development Network Lecture: Review of Current Status of Studies Restoring Airway Surface Liquid Invited Speaker, CHEST 9th Pediatric Fellows Conference Lecture: Pulmonary Function Testing as Applied to the Wheezing Infant Invited Speaker, Duke Airway Biology Forum Lecture: Infant Pulmonary Function Testing State of Art Invited Speaker, American Thoracic Society Annual Conference, Clinical Workshop Lecture: Implementing Infant Pulmonary Function Testing into Clinical Practice Moderator and featured speaker, American Thoracic Society Annual Conference Lecture: Clinical and Research Outcome Measures of CF Lung Disease Invited Speaker, Cincinnati Children's Hospital Lecture: Infant PFTs as a Clinical Outcome Measures: Are we there yet? Invited Speaker, CHEST 9th Pediatric Fellows Conference Lecture: Pulmonary Function Testing as Applied to the Wheezing Infant Invited Speaker, North American Cystic Fibrosis Conference Symposium Lecture: Using Diagnostic Tools in the Young Child: X-rays and Pulmonary Function Facilitator, American Thoracic Society Annual Conference Thematic Poster Session: Cystic Fibrosis: Translational and Clinical Science Invited Speaker, American Thoracic Society Annual Conference Lecture: Infant Pulmonary Function Testing: Is There a Role in Early Wheezing? Session Chair, American Thoracic Society Annual Conference Postgraduate Course, Lung Function Testing in Young Children: Clinical and Research Applications Invited Speaker, Indiana University School of Medicine Lecture: Detecting Early Cystic Fibrosis Lung Disease Co-Chair and Speaker, North American Cystic Fibrosis Conference Symposium: Measuring Early CF Lung Disease Invited Speaker, North American Cystic Fibrosis Conference Course: Introduction to CF Clinical Research Lecture: Data and Specimen Banking Invited Speaker, CHEST Lecture: Advances in Infant Pulmonary Function Testing Invited Speaker, CIPP (Congress of International Pediatric Pulmonology) Postgraduate Course, Assessment of Lung Function in Preschool Children Lecture: Preschool Spirometry Moderator and Featured Speaker, American Thoracic Society Annual Conference Lecture: Recent progress and clinical applicability of infant lung function testing Sunrise Seminar, American Thoracic Society Annual Conference Lecture: Incorporating Infant PFTs into Clinical Practice Invited Speaker, FOCUS on Respiratory Care & Sleep Medicine Conference Lecture: Evaluating Respiratory Function in Children Moderator and Featured Speaker, American Thoracic Society Annual Conference Lecture: Advances in Assessment and Treatment of CF Lung Disease Facilitator, American Thoracic Society Annual Conference Thematic Poster Session: Measurement Techniques for Pediatric Lung Disease 18 2004 2003 2002 2000-02 1998 1996 European Respiratory Society School Course on Assessment and Interpretation of Infant Lung Function Nice, France Lectures: The Infant Pulmonary Lab, Collins Medical Clinical Usefulness in Individual Infants? Full Forced Expiratory Maneuvers Sunrise Seminar, American Thoracic Society Annual Conference Lecture: Implementation of Infant Pulmonary Function Testing As An Integral Part of the Pediatric Pulmonary Practice Respiratory Care Journal Conference Keystone, Colorado Lecture: Diagnostics Infant PFT Round table at the NACF Conference Moderator Pediatric Clinical Fellows Session at the CF Conference: Moderator. Pediatric Clinical Fellows Session at the Cystic Fibrosis Conference Lecture: Follow-up of a Patient with Cystic Fibrosis who required Mechanical Ventilation as an Infant Grand Rounds: 2014 Grand Rounds, Children’s Hospital at Montefiore The Changing Face of Cystic Fibrosis 2013 Grand Rounds, East Tennessee State University The Changing Face of Cystic Fibrosis 2012 Grand Rounds, Riley Hospital for Children The Changing Face of Cystic Fibrosis 2007 Grand Rounds, Wilmington AHEC Obstructive Sleep Apnea 2005 Grand Rounds, UNC Morbidity and Mortality; Enteropatheca Dermatitis and Cystic Fibrosis 2004 Grand Rounds, Moses Cone Hospital Pulmonary Function Testing in Infants and Young Children 2004 Grand Rounds, UNC Infant Pulmonary Function Testing 2002 Grand Rounds, Wake Medical Center Obstructive Sleep Apnea 2002 Grand Rounds, Moses Cone Hospital Obstructive Sleep Apnea 2001 Grand Rounds, Rex Hospital Infant Pulmonary Function Tests as a Clinical Research Tool Regional/University: 2013 Section of Adult Pulmonology 19 2012 2012 2012 2012 2011 2010 2007-11 2007 2005 2004 2003-11 2001 2001-04 2001 2000 2000 1997 Identifying, Validating and Using Structural and Physiologic Endpoints to Assess Respiratory Disease in Young Children Department of Cellular and Integrative Physiology Research Seminar: Using Physiologic and Structural Endpoint to Assess Respiratory Disease in Young Children Riley Hospital for Children Pediatric Conference Lung Function Testing in Children Morris Green Scholars Noon Lecture Successful Manuscript Preparation Indiana ALA Board Meeting Evaluating Early Lung Disease in Young Children with Cystic Fibrosis UNC Annual Fellows Symposium Successful Manuscript Preparation UNC Cystic Fibrosis Research Seminar Developing Outcomes in Young Children with Lung Disease UNC Pediatric Pulmonology Physiology Series Infant Lung Function Testing UNC Faculty Workshop Faculty Development and Mentoring UNC Pediatric Noon Conference Pediatric Lung Function Testing UNC Cystic Fibrosis Clinical Research Seminar Detecting Early CF Lung Disease: HRCT of the Chest Multiple Breath Washout UNC Pediatric Pulmonary Fellows’ Conference Pediatric Spirometry UNC Cystic Fibrosis Clinical Research Seminar High Resolution Computed Tomography with Controlled Ventilation UNC Pediatric Noon Conference Obstructive Sleep Apnea UNC Pediatric Pulmonary Fellows’ Conference Infant Lung Function Testing UNC Neonatology Fellows’ Conference Infant Pulmonary Function Tests UNC Cystic Fibrosis Clinical Research Seminar Infant Pulmonary Function Tests Respiratory Care Department’s Continuing Education for the Healthcare Provider Mechanical Ventilation and the Asthmatic Patient Course Director: 2004-08 Pediatric Pulmonology Rotation Director of the Residents, Medical Students Research Mentor: 2014- present Shawn Ahlfeld, Assistant Professor, Neonatology Project: Long term follow-up of children with chronic lung disease of prematuriy 20 2013-present Ashley Deschamp, Pediatric Pulmonary Fellow Project: Assessing Stool Microbiome in the Young Infant with CF 2013-present Kirsten Kloepfer, Assistant Professor, Pediatric Pulmonology, Allergy, Sleep Project: Viral Microbiome in Infants of Mothers with Asthma 2012-present Tonia Gardner, Pediatric Pulmonary Fellow Project: Aminoglycoside Nephrotoxicity in Pediatric Cystic Fibrosis Patients 2011-present Ioana Cristea, Pediatric Pulmonary Fellow/Faculty Projects: 1. Long Term Outcome of Children with BPD Who Were Discharged on Home Positive Pressure Ventilation 2. Improving Communication with PCPs caring for CF patients 2010-2014 Jennifer Goralski, Pulmonary fellow/Faculty Projects: Eosinophilic Esophagitis in CF; Aerosol Treatment in Children 2008-11 Kavita Patel, Pediatric Pulmonology Fellow Project: Disease Markers in Exhaled Breath Condensate (EBC) of Infants 2008-present Adam Shapiro, Pediatric Pulmonology Fellow, Assistant Professor (Montreal) Project: Primary Ciliary Dyskinesia 2007-10 Chandar Ramanathan; Pediatric Pulmonology Fellow Project: Evaluating Regulators of Mucus Clearance in Childhood Lung Disease Grant Support: Cystic Fibrosis Foundation Fellowship Grant (1st2nd 3rd year) 2007-present Jessica Pittman; Pediatric Pulmonology Fellow Projects: 1. Spirometry in Biracial Children – Assessing the Adequacy of Current NHANES Race-Based Reference Equations 2. Early Onset and Progression of Primary Ciliary Dyskinesia Lung Disease Prior to 10 Years of Age 2007-present Ruchika Goel; Masters of Public Health Student (Practicum) Project: Physiologic, Inflammatory and Airway Remodeling Findings in Infants with Cystic Fibrosis 2005-07 Elisabeth Dellon; Pediatric Pulmonology Fellow Project: Hypertonic Saline in Infants and Young Children with Cystic Fibrosis 2004-present Stacey Peterson-Carmichael; Pediatric Pulmonology/ICU Fellow Projects: 1. Effect of Inhaled Corticosteroids on Infant Pulmonary Function after RSV Bronchiolitis 2. Physiologic, Inflammatory and Airway Remodeling Findings in Infants with Cystic Fibrosis Grant Support: Medimmune Pediatric Fellowship Grant 2002-05 John Saito; Pediatric Pulmonology Fellow Project: Physiologic, Bronchoscopic and Bronchoalveolar Lavage Fluid Findings In Young Children with Recurrent Wheeze and Cough Residency Class Advisor 2004-07 Pediatric Resident Class 2001-04 Pediatric Resident Class Scholarly Oversight Committee; PhD Thesis Reviews: 2012 Fiona Healy, MB, BCh, ZBAO (Hons), MRCPI; University College Dublin Lung Structure and Function in Infants with Congenital Diaphragmatic Hernia 21 2009 2008 2004-07 Deidre Washington, PhD; University of North Carolina at Chapel Hill Thesis: The Effect of Patient Race on Patient-Provider Communication with Pediatric Asthma Patients Catherine Gangell, BsC; University of Western Australia Thesis: Evaluation of the Forced Oscillation Technique for Clinical Assessment of Young Children with Cystic Fibrosis Kristy Herman; Neonatology Fellow Attending on Clinical Service I attend the clinical service 4 weeks annually. During these weeks, I give lectures to the residents and medical students. Lists of these lectures are below: Lung function Testing Cystic Fibrosis: Pathophysiology and Management Evaluation of the Noisy Breathing Infant Evaluation of the Infant with Recurrent Wheeze and Cough Chronic Cough Grants: Ongoing Research Support: SHIP14K0 (Rosenfeld, Ratjen, Davis, PI) 11/28/2011CFF $141,547 Multicenter study evaluating efficacy of hypertonic saline in preschoolers 1R01HL116211-01 (Davis/Ferkol/Ranganathan) 9/26/2012-06/30/2016 NIH $1,995,535 Viral Pathogenesis of Early Cystic Fibrosis Lung Disease The goal is to determine the frequency of respiratory virus infections and their impact on the evolution of endobronchial bacterial infection and inflammation in CF infants. 5 R01 HL105702-02 (Davis/Voynow/Cotton/Poindexter (PI)) 9/1/2011-8/31/2015 NIH/NHLBI Gastrin-Releasing Peptide and Bronchopulmonary Dysplasia Two center study evaluating gastrin-releasing peptide as a predictor of pulmonary morbidity in bronchopulmonary dysplasia Role: PI RFA HL 10-017 (R01) (PIs: Davis, Zdanksi, Superfine) 10/1/2010 -9/30/2014 NIH/NHLBI $2,600,000 Direct Predictive Modeling for Treatment of Upper Airway Obstruction We hypothesize that a functional computational model that simulates the mechanical and aerodynamic behavior of the upper airway in infants with Pierre Robin sequence and laryngeal lesion (e.g. subglottic stenosis) can be used as an effective diagnostic and treatment planning tool, reducing failures of initial treatment and avoiding potentially unnecessary future complications and interventions 22 5 U54 RR019480-02 (Knowles-PI) 8/6/2004 – 7/31/2014 NIH (National Center for Research Resources) $6,225,000 (Direct and Indirect) Genetic Disorders of Mucociliary Clearance A five center consortium evaluating rare diseases of the airways, which involve defects in mucociliary clearance. 1U01HL092931-01 (Rosenfeld-PI; Davis-PI) 10/1/08-7/31/14 NIH/NHLBI $83,692 Subcontract with Childrens Hospital Regional Medical Center (Davis – PI) Infant Study of Inhaled Saline in Cystic Fibrosis (ISIS) This multiple center study evaluates 7% HS inhaled twice daily for 48 weeks versus twice daily inhalation of normal saline (placebo) in CF infants (4 to 15 months at enrollment). ISIS07KO (Davis-PI; Rosenfeld-PI) 10/01/2007 – 9/30/14 Cystic Fibrosis Foundation $836,587 Infant Study of Inhaled Saline in Cystic Fibrosis (ISIS) This multiple center study evaluates 7% HS inhaled twice daily for 48 weeks versus twice daily inhalation of normal saline (placebo) in 150 CF infants (4 to 15 months at enrollment). DAVIS08Y2 (Davis-PI) 1/1/14-12/31/14 Cystic Fibrosis Foundation Therapeutics, Inc $39,122 Infant and Preschool Pulmonary Function Testing Core The goal of this project is to ensure that TDN sites are performing infant and preschool lung function testing as outlined in the protocols and Standard Operating Procedures and that the data collected is of research quality. Completed Research Support: RETSCH09Y0 (Retsch-Bogart – PI) 1/1/11-12/31/11 Cystic Fibrosis Foundation Therapeutics, Inc. Therapeutic Development Center Role: Co-PI $160,000 1 P50 HL 084934-01 (Boucher-PI) 9/15/12006– 7/31/2011 1.61 calendar NIH/NHLBI $2,174,432 SCCOR in Host Factors in Chronic Lung Disease The purpose of this study is to assess host defense factors contributing to exacerbations of disease in COPD and CF. NC TraCS Institute 5/1/09-7/31/10 Role: PI Validation of the Mulitple Breath Washout Device for Asssessment of Pediatric Lung Diseases 1R13HL105073-01 (Davis-PI) 9/30/2010-10/1/2010 Role: PI NHLBI $15,000 Primary Ciliary Dyskinesia and Overlapping Syndromes Conference 23 Genentech, Inc. (Davis-PI) 1/1/08-12/31/09 .24 Calendar Consulting Agreement for Protocol Z4240g $11,000 Dr. Davis acted as consultant for oscillometry and spirometry testing in preschool children. Genentech, Inc. (Davis-Site PI) 6/24/08-6/23/11 .84 Calendar Z4240g A Phase IV, Multicenter, Randomized, Double Blind, Placebo Controlled Trial of Pulmozyme in 3- TO 5-Year-Old Patients with CF $43,283 This was a Phase IV, multicenter, randomized, double-blind, placebo-controlled trail designed to evaluate the effect of study drug on pulmonary function, health related quality of life (HRQOL), and respiratory symptoms in 3 to 5 year old children with Cystic Fibrosis. R01 HL069837 (Sleath -PI) 8/1/2005 – 7/31/2009 1.04 calendar NIH $280,477 Children and Asthma: Communication and Outcomes The project is focused on a neglected area within children's health services research, the relationship between provider-child-caregiver communication during pediatric asthma visits and treatment adherence. Cystic Fibrosis Clinical Research Grant 7/1/05-6/31/08 9.3% Cystic Fibrosis Foundation $18,597 (1st year); $92,077 (3 years) Spirometry as an Outcome Measure in Preschool Children with CF Kerby04A0 An 8 center study evaluating lung function measurements longitudinally in preschoolers with cystic fibrosis and age-matched controls Role Co-PI Cystic Fibrosis Foundation A Pilot Study to Evaluate the Tolerability of Inhaled Hypertonic Saline in Infants with Cystic Fibrosis Role: Co-PI 7/07-6/08 $20,000 7% Cystic Fibrosis Foundation 2/1/05-1/31/07 15% Cystic Fibrosis Clinical Research Grant $47,365 (1st year); $69,234 (2 years) Hypertonic Saline in Infant and Young Children with CF A single center study assessing the safety of hypertonic saline in infants and young children with cystic fibrosis Role PI DAVIS08Y2 2/1/03-1/31/07 30% Cystic Fibrosis Foundation $75,190 (last year) $1,000,000 (over 3 years) Evaluation of Pulmonary Function Tests from Raised Lung Volumes as Outcome Measures for Clinical Trials in Infants with Cystic Fibrosis A 10 center study evaluating longitudinal changes of infant lung function testing over 1 year in infants with cystic fibrosis Role PI 24 Cystic Fibrosis Clinical Research Grant 7/1/02-6/30/05 Cystic Fibrosis Foundation $80,000 Detecting Early, Reversible CF Lung Disease on HRCT This study is correlating changes on HRCT of the chest to bronchoscopy findings. Role PI Harry Shwachman Clinical Investigator Award 7/1/00-6/30/03 Cystic Fibrosis Foundation $225,000 Physiologic and BALF Markers of Early CF Lung Disease This study is investigated early markers of cystic fibrosis lung disease noted on infant lung function testing and bronchoscopy. Role: PI Thomas H. Davis Fellowship Award 7/1/00-6/30/02 American Lung Association $60,000 Physiologic Versus Bronchoscopic Markers in Wheezy Infants This study correlated physiologic markers on infant lung function testing to bronchoscopy findings. Role: PI Cystic Fibrosis Foundation Clinical Fellowship Grant 7/1998-6/1999 Density Dependence of Maximal Flows in CF Infants $55,000 Principal Investigator: Davis Sponsor: Robert S. Tepper, MD, PhD Cystic Fibrosis Foundation Clinical Fellowship Grant 7/1997-6/1998 Principal Investigator: Davis Sponsor: Howard Eigen, MD $31,400 Cystic Fibrosis Foundation Clinical Fellowship Grant 7/1996-6/1997 Principal Investigator: Davis Sponsor: Howard Eigen, MD Professional Service: Committees: International/National: 2014-present Board of Directors American Thoracic Society 2014-present Council, Member for Pulmonology Society of Pediatric Research 2014-present Committee member, NIH sponsored AsthmaNet DSMB 2013 NHLBI Ad Hoc Reviewer; Special Emphasis Review Panel 2013-present Research Advocacy Committee American Thoracic Society 2012-present Midwest Society for Pediatric Research Member 2010 Faculty Member Seventh Annual Respiratory Disease Young Investigators' Forum 25 2009-11 2007-present 2005- 11 2003-05 2005-08 2003-04 2000-present Pediatric Program Committee American Thoracic Society Pediatric Chair and Chair Elect Pediatric Planning Committee American Thoracic Society Member Pediatric Program Committee American Thoracic Society Member Infant/ Preschool PFT Standardization Taskforce American Thoracic Society USA Co-Chair National Resource Center Committee Therapeutic Development Network, Cystic Fibrosis Foundation Chair Pediatric Assembly Nominating Committee American Thoracic Society Member Outcomes for Young Children with CF Working Committee Therapeutic Development Network, Cystic Fibrosis Foundation Co-Director Indiana: 2012-present Department of Pediatrics Promotion Committee for Tenure 2011-present Morris Green Scholar Executive Committee UNC: 2007-11 Faculty Development Committee, Department of Pediatrics Chair 2007-11 Promotions Committee Department of Pediatrics Member 2005 & 2007 Department of Pediatrics Evening of Scholarship Judge of Clinical Abstracts 2003-05 Pediatric Clerkship Advisory Committee Department of Pediatrics Member 2002-08 Pediatric Intern Selection Committee Department of Pediatrics Member 2001-02 Promotions Committee Department of Pediatrics Member 26 Professional Membership: American Academy of Pediatrics American Thoracic Society North Carolina Medical Society Society of Pediatric Research Other UNC Administrative Activities: 2001-07 2001-11 2001-11 Resident Advisor Department of Pediatrics Associate Director of PFT Laboratory Medical Director of Infant PFT Laboratory Reviewer: American Journal of Respiratory and Critical Care Medicine Archives of Pediatric Adolescent Medicine Austrian Science Fund Chest European Journal of Applied Physiology European Respiratory Journal Health Research Board of Ireland Health Services, Public Health Research Board Medical Research Council(England) Journal of Applied Physiology Journal of Cystic Fibrosis Lancet New England Journal of Medicine The Journal of Pediatrics Pediatric Pulmonology Pediatric Research Respiratory Physiology and Neurobiology Thorax 27