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STEPHANIE D. DAVIS, M.D.
Curriculum Vitae
Present Positions:
Section Director, Pediatric Pulmonology, Allergy and Sleep Medicine
James Whitcomb Riley Hospital for Children
Indiana University Medical Center
Professor of Cellular and Integrative Physiology
James Whitcomb Riley Hospital for Children
Indiana University Medical Center
Present Address:
Personal Data:
Name:
Home Address:
Phone Number:
Date of Birth:
Marital Status:
Education:
07/96-06/99
07/94-06/96
07/93-06/94
08/89-05/93
Indiana University School of Medicine
James Whitcomb Riley Hospital for Children
705 Riley Hospital Dr. ROC 4270
Indianapolis, IN 46202-5225
(317) 948-7769 Admin. Asst.
(317) 944-5791 Fax
[email protected]
Stephanie Duggins Davis, M.D.
7333 Fox Hollow Ridge
Zionsville, IN 46077
317-344-2873
May 10, 1967
Married – Samuel P. Davis, III
Profession – Otolaryngology
Children – Harrison, Jackson, Parker
James Whitcomb Riley Hospital for Children
Indiana University Medical Center
Director: Howard Eigen, M.D.
Fellowship: Pediatric Pulmonary
James Whitcomb Riley Hospital for Children
Indiana University Medical Center
Chairman: Richard Schreiner, M.D.
Residency: Pediatrics
James Whitcomb Riley Hospital for Children
Indiana University Medical Center
Chairman: Richard Schreiner, M.D.
Internship: Pediatrics
Bowman Gray Medical School
Wake Forest University
1
08/85-05/89
Winston-Salem, North Carolina
Degree: Doctor of Medicine
May 17, 1993
University of North Carolina
Chapel Hill, North Carolina
Degree: Bachelor of Science in Biology
May 14, 1989
Professional Experience:
08/2013-present
11/28/11-present
Associate Editor, Pediatric Pulmonology Journal
Section Director, Pediatric Pulmonology, Allergy and Sleep Medicine
James Whitcomb Riley Hospital for Children
Indiana University Medical Center
Date of Appointment: November 28, 2011
11/28/11-present
Professor of Cellular and Integrative Physiology
James Whitcomb Riley Hospital for Children
Indiana University School of Medicine
Date of Appointment: November 28, 2011
2011-present
Adjunct Professor of Pediatrics
University of North Carolina at Chapel Hill
07/01/09-08/01/11
Division Chief of Pediatric Pulmonology
University of North Carolina at Chapel Hill
Date of appointment: July 1, 2009
07/01/07-6/30/11
Fellowship Program Director
University of North Carolina at Chapel Hill
Date of appointment: July 1, 2007
08/15/06-11/23/11
Associate Professor of Pediatrics
University of North Carolina at Chapel Hill
Date of appointment: August 15, 2006
08/16/99 – 08/14/06 Assistant Professor of Pediatrics
University of North Carolina at Chapel Hill
Date of appointment: August 16, 1999
Certification and Licensure:
A. Certification:
Pediatric Pulmonology
American Board of Pediatrics
National Board of Medical Examiners
2000, recertified in 2007
1996, recertified in 2002
1994
#00610
#058486
#437274
B. Licensure:
North Carolina
1999-2012
#9900470
Indiana
1997-1999, 2011-present
#01044048
Honors and Awards:
2014-17
Council member for Pulmonology, Society for Pediatric Research
2012
Midwest Society for Pediatric Research
2
2009-2013
2008
2009
2006
1998
1997
Best Doctors
Mid-Career Leadership Initiative
University of North Carolina at Chapel Hill
Academic Leadership Program
University of North Carolina at Chapel Hill
Society of Pediatric Research
University of North Carolina at Chapel Hill
Alpha Omega Alpha
Indiana University School of Medicine
Distinguished Residents and Fellows Asthma
Education Scholarship Program; London, England
Bibliography:
Book Editor:
Davis SD, Davis, SD, Koumbourlis A, Eber E, eds. Diagnostic Tests in Pediatric
Pulmonology, Springer 2015
Book Chapters:
1. Shapiro AJ, Chilvers MA, Davis SD, Leigh MW. Nasal Nitric Oxide and Ciliary
Videomicroscopy: Tests Used for Diagnosing Primary Ciliary Dyskinesia. In: Davis, SD,
Koumbourlis A, Eber E, eds. Diagnostic Tests in Pediatric Pulmonology, Springer 2015
2. Kim YJ, Kercsmar C, Davis SD. Fractional Exhaled Nitric Oxide: Indication and
Interpretation. In: Davis, SD, Koumbourlis A, Eber E, eds. Diagnostic Tests in Pediatric
Pulmonology, Springer 2015
3. Castile RG, Davis, SD. Pulmonary Function Testing in Children. In: Wilmott RW, Bush
A, Ratjen F, Deterding R, Boat T, Chernick V, eds. Kendig & Chernick’s Disorders of
the Respiratory Tract in Children, 8th edition.
4. Davis SD, Pittman J. Lung Function Testing in Infants. In: Allen JA, Panitch HB,
Rubenstein RC, eds. Cystic Fibrosis. New York: Informa Healthcare, 2010; 242: 123147.
5. Davis, SD, Gappa, M, Rosenfeld, M. Respiratory Mechanics. Paediatric Pulmonary
Function Testing. In: Hammer J, Eber E, eds. Prog. Respir Res, Basel, Karger, 2005; 33:
20-33.
Refereed Articles:
1. Cristea IA, Ackerman V, Swigonski N, Yu Z, Slaven J, Davis SD. “Physiologic Findings
in Children Previously Ventilator Dependent at Home due to Bronchopulmonary
Dysplasia.” Pediatr Pulmonol ; 2014; in press.
2. Pittman JE, Cutting G, Davis SD, Ferkol T, Boucher R.” Cystic Fibrosis: NHLBI
Workshop on the Primary Prevention of Chronic Lung Diseases.” Annals of the American
Thoracic Society, April 2014; 11 (Suppl 3), S161-8
3. Hong Y, Davis B, Marron JS, Kwitt R, Singh N, Kimbell JS, Pitkin E, Superfine R, Davis
SD, Zdanski CJ, Niethammer M. “Statistical Atlas Construction via Weighted Functional
Boxplots.” Med Image Anal. 2014 March.
4. Brumback LC, Baines A, Ratjen F, Davis SD, Daniel SL, Quittner A, Rosenfeld M.
“Pulmonary exacerbations and parent-reported outcomes in children < 6 years with cystic
fibrosis.” Pediatr Pulmonol. 2014 March.
3
5. Shapiro AJ, Davis SD, Ferkol T, Dell SD, Rosenfeld M, Olivier KN, Sagel SD, Milla C,
Zariwala MA, Wolf W, Carson JL, Hazucha MJ, Burns K, Robinson B, Knowles MR and
Leigh MW. “Laterality Defects other than Situs Inversus Totalis in Primary Ciliary
Dyskinesia: Insights into Situs Ambiguus and Heterotaxy.” CHEST. 2014 Feb 27. doi:
10.1378/chest.13-1704. [Epub ahead of print]
6. Knowles MR, Ostrowski LE, Leigh MW, Sears PR, Davis SD, Wolf WE, Hazucha MJ,
Carson JL, Olivier KN, Sagel SD, Rosenfeld M, Ferkol TW, Dell SD, Milla CE, Randell
SH, Yin W, Sannuti A, Metjian HM, Noone PG, Noone PJ, Olson CA, Patrone MV,
Dang H, Lee HS, Hurd TW, Gee HY, Otto EA, Halbritter J, Kohl S, Kircher M, Krischer
J, Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Zariwala MA. “Mutations in
RSPH1 Cause Primary Ciliary Dyskinesia with a Unique Clinical and Ciliary
Phenotype.” Am J Respir Crit Care Med. 2014 Feb 25. [Epub ahead of print]
7. Goralski JL, Davis SD. “Challenges and Limitations of Testing Efficacy of Aerosol
Device Delivery in Young Children.” J Aerosol Med Pulm Drug Deliv. 2014 Jan 29.
[Epub ahead of print]
8. Carpenter DM, Stover A, Slota C, Ayala GX, Yeatts K, Tudor G, Davis S, Williams D,
Sleath B. “An evaluation of physicians’ engagement of children with asthma in
treatment-related discussions.” J Child Health Care, 2014 18: 216.
9. Leigh MW, Hazucha MJ, Chawla KK, Baker BR, Shapiro AJ, Brown DE, LaVange LM,
Horton BJ, Qaqish B, Carson JL, Davis SD, Dell SD, Ferkol TW, Atkinson JJ, Olivier
KN, Sagel SD, Rosenfeld M, Milla C, Lee HS, Krischer J, Zariwala MA, Knowles MR;
“Standardizing Nasal Nitric Oxide Measurement as a Test for Primary Ciliary
Dyskinesia.” Ann Am Thorac Soc 2013; 2013 Dec; 10 (6):574-81.
10. Rosenfeld M, Farrell PM, Kloster M, Swanson JO, Vu T, Brumback L, Acton JD, Castile
RG, Colin AA, Conrad CK, Hart MA, Kerby GS, Hiatt PW, Mogayzel PJ, Johnson RC,
Davis SD. “Association of Lung Function, Chest Radiographs and Clinical Features in
Infants with Cystic Fibrosis.” ERJ; 2013 Dec; 42(6):1545-52. doi:10.1183/
09031936.00138412. Epub 2013.
11. Davies J, Sheridan H, Bell N, Cunningham S, Davis SD, Elborn JS, Milla CE, Starner
TD, Weiner DJ, Lee PS, Ratjen F. “Assessment of clinical response to Ivacaftor with
lung clearance index in cystic fibrosis patients with a G551D-CFTR mutation and
preserved spirometry: a randomized controlled trial.” Lancet Respir Med. 2013 Oct;
1(8):630-8. doi: 10.1016/S2213-2600(13)70182-6. Epub 2013 Sep 10
12. Knowles MR, Daniels LA, Davis SD, Zariwala MA, Leigh MW; “Primary ciliary
dyskinesia. Recent advances in diagnostics, genetics, and characterization of clinical
disease.” Am J Resp Crit Care Med; 2013; Oct 15; 188(8):913-22.
13. Austin-Tse C, Halbritter J, Zariwala MA, Gilberti RM, Gee HY, Hellman N, Pathak N,
Liu Y, Panizzi JR, Patel-King RS, Tritschler D, Bower R, O'Toole E, Porath JD, Hurd
TW, Chaki M, Diaz KA, Kohl S, Lovric S, Hwang DY, Braun DA, Schueler M, Airik R,
Otto EA, Leigh MW, Noone PG, Carson JL, Davis SD, Pittman JE, Ferkol TW, Atkinson
JJ, Olivier KN, Sagel SD, Dell SD, Rosenfeld M, Milla CE, Loges NT, Omran H, Porter
ME, King SM, Knowles MR, Drummond IA, Hildebrandt F. “Zebrafish Ciliopathy
Screen Plus Human Mutational Analysis Identifies C21orf59 and CCSC65 Defects as
Causing Primary Ciliary Dyskensia.” Am J Hum Genet. 2013 Oct 3; 93(4):672-86. doi:
10.1016/j.ajhg.2013.08.015
4
14. Knowles MR, Ostrowski LE, Loges NT, Hurd T, Leigh MW, Huang L, Wolf WE,
Carson JL, Hazucha MJ, Yin W, Davis SD, Dell SD, Ferkol TW, Sagel SD, Olivier KN,
Jahnke C, Olbrich H, Werner C, Raidt J, Wallmeier J, Pennekamp P, Dougherty GW,
Hjeij R, Gee HY, Otto EA, Halbritter J, Chaki M, Diaz KA, Braun DA, Porath JD,
Schueler M, Baktai G, Griese M, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA,
Hildebrandt F, Shendure J, Omran H, Zariwala MA. “Mutations in SPAG1 cause primary
ciliary dyskinesia associated with defective outer and inner dynein arms.” Am J Hum
Genet. 2013 Oct 3; 93(4):711-20. doi: 10.1016/j.ajhg.2013.07.025. Epub 2013 Sep 19.
15. Calloway HE, Kimbell JS, Davis SD, Retsch-Bogart GZ, Pitkin EA, Abode K, Superfine
R, Zdanski CJ; “Comparison of endoscopic versus 3D CT derived airway
measurements.” The Laryngoscope; 2013 Sep; 123 (9): 2136-2141.
16. Subbarao P, Stanojevic S, Brown M, Jensen R, Rosenfeld M, Davis S, Brumback L,
Gustafsson P, Ratjen F; “Lung Clearance Index as an Outcome Measure for Clinical
Trials in Young Children with Cystic Fibrosis: A Pilot Study using Inhaled Hypertonic
Saline.” Am J Resp Crit Care Med; 2013; Aug 15; 188(4):456-60.
17. Daniels ML, Leigh MW, Davis SD, Armstrong MC, Carson JL, Hazucha M, Dell SD,
Eriksson M, Collins FS, Knowles MR, Zariwala MA; “Founder Mutation in RSPH4A
Identified in Patients of Hispanic Descent with Primary Ciliary Dyskinesia.” Hum Mutat.
2013 Jun 24. doi: 10.1002/humu.22371. Epub 2013 Aug 6.
18. Cristea AI, Carroll A, Davis SD, Swigonski N, Ackerman V; “Outcomes of Children
with Severe Bronchopulmonary Dysplasia Who Were Ventilator Dependent at Home.”
Pediatrics; 2013 Sep; 132(3):e727-34. doi: 10.1542/peds.2012-2990. Epub 2013 Aug 5.
19. Sobush KT, Thornburg CD, Voynow JA, Davis SD, Peterson-Carmichael SL. “A 2-yearold girl with co-inherited cystic fibrosis and sickle cell-β+ thalassemia presenting with
recurrent vaso-occlusive events during cystic fibrosis pulmonary exacerbations: a case
report.” J Med Case Rep. 2013 Jul 26; 7(1):203. doi: 10.1186/1752-1947-7-203.
20. Sheehan D, Davis SD, Borowitz D. “From Triple Threat to Octopus: Reflections on the
Roles of Pediatric Division Chiefs in the Current Era.” Journal of Pediatrics; 2013; Jul;
163(1):4-5. doi: 10.1016/j.jpeds.2013.04.009.
21. Peterson-Carmichael S, Rosenfeld M, Ascher SB, Hornik CP, Arets HGM, Davis SD,
Hall G. “Survey of Clinical Infant Lung Function Testing Practices.” Pediatr Pulmonol;
2013 Jun 13. doi: 10.1002/ppul.22807. [Epub ahead of print].
22. Carpenter DM, Ayala GX, Williams DM, Yeatts KB, Davis SD, Sleath B. “The
relationship between patient-provider communication and quality of life for children with
asthma and their caregivers.” J Asthma; 2013 Jun 3 Epub 2013 Jul 4.
23. Davis SD, Ferkol T. “Identifying the Origins of Cystic Fibrosis Lung Disease.” N Engl J
Med; 2013 May 23;368(21):2026-8
24. Rosenfeld M, Allen J, Arets B, Aurora P, Beydon N, Calogero C, Castile R, Davis SD,
Fuchs S, Gappa M, Gustaffson PM, Hall GL, Jones M, Kirkby J, Kraemer R, Lombardi
E, Lum S, Mayer H, Merkus P, Nielsen KG, Oliver C, Oostveen E, Ranganathan S, Ren
C, Robinson P, Seddon P, Sly P, Sockrider M, Sonnappa S, Stocks J, Subbarao P, Tepper
RS, Vilozni D; On Behalf of the American Thoracic Society Ad Hoc Committee; “An
Official American Thoracic Society Workshop Report: Optimal Lung Function Tests for
Monitoring Cystic Fibrosis, Bronchopulmonary Dysplasia, and Recurrent Wheezing in
Children Less than 6 Years of Age.” Ann Am Thoracic Soc; 2013; Apr; 10 (2):S1-S11.
doi: 10.1513/ AnnalsATS.201301-017ST.
5
25. Patel K, Davis SD, Johnson R, Esther CR; “Exhaled breath condensate purines correlate
with lung function in infants and preschoolers.” Pediatri Pulmonol; 2013 Feb; 48 (2):
182-7.
26. Knowles MR, Leigh MW, Ostrowski LE, Huang L, Carson JL, Hazucha MJ, Yin W,
Berg JS, Davis SD, Dell SD, Ferkol TW, Rosenfeld M, Sagel SD, Milla CE, Olivier KN,
Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Shendure J, Zariwala MA; “Genetic
Disorders of Mucociliary Clearance Consortium. Exome sequencing Identifies Mutation
in CCDC114 as a Cause of Primary Ciliary Dyskinesia.” Am J Hum Genet. 2013 Jan 10:
92 (1): 99-106.
27. Goralski JL, Lercher D, Davis SD, Dellon E; “Eosinophilic Esophagitis in Cystic
Fibrosis: a Case Series and Review of the Literature.” Journal of Cystic Fibrosis; 2013
Jan; 12 (1): 9-14.
28. Brumback LC, Davis SD, Kerby, GS, Kloster MS, Johnson, R, Castile R, Hiatt PW, Hart
M, Rosenfeld M; “Lung Function From Infancy to Preschool in a Cohort of Children
with Cystic Fibrosis.” European Respiratory Journal; 2013 Jan; 41 1): 60-6.
29. Montgomery G, Davis SD; “Drug therapies to improve mucus clearance in patients with
cystic fibrosis.” Current Medical Literature-Cystic Fibrosis; 2012; 2 (4): 85-90.
30. Pittman, JE, Johnson RC, Jones PW, Davis SD; “Variability of a Closed, Rebreathing
Setup for Multiple Breath Wash-Out Testing in Children.” Pediatri Pulmonol; 2012 Dec;
47 (12): 1242-50.
31. Sleath B, Carpenter DM, Slota C, Williams D, Tudor G, Yeatts K, Davis S, Ayala GX.
“Communication during pediatric asthma visits and self-reported asthma medication
adherence.” Pediatrics. 2012 Oct; 130 (4): 627-33.
32. Sleath BL, Carpenter DM, Ayala GX, Williams D, Davis SD, Tudor G, Yeatts K, Gillette
C; “Communication during pediatric asthma visit and child asthma medication device
technique one month later.” Journal of Asthma; 2012 Nov; 49 (9): 918-25.
33. Kerby GS, Rosenfeld M, Ren CL, Mayer OH, Brumback L, Castile R, Hart MA, Hiatt P,
Kloster M, Johnson R, Jones P, Davis SD; “Lung Function Distinguishes Preschool
Children with CF from Healthy Controls in a Multi-Center Setting.” Pediatr Pulmonol;
2012 Jun; 47 (6): 597-605.
34. Ren CL, Rosenfeld M, Mayer OH, Davis SD, Kloster M, Castile RG, Hiatt PW, Hart M,
Johnson R, Jones P, Brumback LC, Kerby GS; “Lung Function and Clinical Features in
Preschool Children with Cystic Fibrosis.” Pediatr Pulmonol; 2012 Jun; 47 (6): 574-81.
35. Rosenfeld M, Ratjen F, Brumback LC, Daniel S, Rowbotham R, McNamara S, Johson R,
Kronmal R, Davis SD for the ISIS Study Group; “Inhaled Hypertonic Saline In Infants
And Children Less Than Six Year of Age With Cystic Fibrosis: The ISIS Randomized
Trial.” JAMA; 2012; May 20:1-9.
36. Knowles M, Leigh M, Carson JL, Davis SD, Dell SD, Ferkol TW, Olivier KN, Sagel SD,
Rosenfeld M, Burns KA, Minnix SL, Armstrong MC, Lori A, Hazucha MJ, Loges NT,
Olbrich H, Becker-Heck A, Schmidts M, Werner C, Orman H, Zariwala MA; “Genetic
Disorders of Mucociliary Clearance Consortium. Mutations of DNAH11 in patients with
primary ciliary dyskinesia with normal ciliary ultrastructure.” Thorax; 2012 May; 67 (5):
433-41.
37. Pittman JE, Johnson RC, Davis SD. “Improvement in pulmonary function following
antibiotics in infants with cystic fibrosis.” Pediatr Pulmonol. 2012 May; 47 (5): 441-6.
6
38. Washington D, Yeatts K, Sleath B, Ayala GX, Gillette C, Williams D, Davis S, Tudor G.
“Communication and education about triggers and environmental control strategies
during pediatric asthma visits.” Patient Educ Couns. 2012 Jan; 86 (1): 63-9.
39. Sleath B, Carpenter DM, Sayner R, Ayala GX, Williams D, Davis SD, Tudor G, Yeatts
K. “Child and caregiver involvement and shared decision making during asthma pediatric
visits.” Journal of Asthma; 2011 Dec; 48 (10): 1022-31.
40. Sleath B, Ayala GX, Washington D, Davis SD, Williams D, Tudor G, Yeatts K, Gillette
C. “Caregiver rating of provider participatory decision-making style and caregiver and
child satisfaction with pediatric asthma visits.” Patient Educ Couns. 2011 Nov; 85(2):
286-9.
41. Davis SD, Knowles M, Leigh M. “Introduction: primary ciliary dyskinesia and
overlapping syndromes.” Proc Am Thorac Soc 2011 Sep; 8(5): 421-2.
42. Ranganathan S, Davis SD, Rosenfeld M. “Clinical Applications of Pediatric Pulmonary
Function Testing.” Pediatric Allergy, Immunology, and Pulmonology 2011; September,
24 (3): 133-137.
43. Sagel SD, Davis SD, Campisi P, Dell SD. “Update of Respiratory Tract Disease in
Children with Primary Ciliary Dyskinesia.” Proc Am Thorac Soc; 2011 sep; 85): 438-43.
44. Sleath BL, Carpenter DM, Ayala GS, Williams DM, Davis S, Tudor G, Yeatts K, Gillette
C. “Provider discussion, education, and question-asking about control medications during
pediatric asthma visits.” International Journal of Pediatrics; 2011; 2011: 212160.
45. Rosenfeld M, Davis SD, Brumback L, Daniel S, Rowbotham R, Johnson R, McNamara
S, Jensen R, Ratjen F. “Inhaled Hypertonic Saline in Infants and Toddlers with Cystic
Fibrosis: Short-Term Tolerability, Adherence and Safety.” Pediatric Pulmonology; 2011,
Jul;46(7):666-71
46. Pittman JE, Van Rie A, Davis SD. “Spirometry in Biracial Children: How adequate are
race-based reference equations?” Archives of Pediatric Adolescent Medicine; 2011;
Jun;165(6):573-4
47. Lesnick BL, Davis SD. “Infant pulmonary function testing: overview of technology and
practical considerations--new current procedural terminology codes effective 2010.”
Chest; 2011 May; 139(5):1197-202.
48. Gillette CM, Loughlin CE, Sleath BL, Williams DM, Davis SD. “Quality of Pulmonary
Function Testing in Three Large Primary Care Pediatric Clinics in Rural North Carolina.”
North Carolina Medical Journal; 2011 Mar-Apr; 72(2):105-10.
49. Sleath B, Ayala G, Gillette, C, Williams D, Davis SD, Tudor G, Yeatts K, Washington D.
“Provider demonstration and assessment of child asthma device technique during
pediatric asthma visits.” Pediatrics; 2011; Apr;127(4):642-8.
50. Olin JT, Burns K, Carson JL, Metjian H, Atkinson JJ, Davis SD, Dell, SD, Ferkol TW,
Milla CE, Olivier KN, Rosenfeld M, Baker B, Leigh MW, Knowles MR, Sagel SD for
the Genetic Disorders of Mucociliary Clearance Consortium. “Diagnostic Yield of Nasal
Scrape Biopsies in Primary Ciliary Dyskinesia: A Multicenter Experience.” Pediatric
Pulmonology; 2011 Jan 31; in press. [Epub ahead of print]
51. Pittman J, Calloway E, Kiser M, Yeatts J, Davis SD, Drumm ML, Schechter M, Leigh
M, Edmond M, Van Rie A, Knowles M. “Age of Psuedomonas aeruginosa Acquisition
and Subsequent Severity of Cystic Fibrosis Lung Disease.” Pediatric Pulmonology;
2010; Dec 30. [Epub ahead of print]
7
52. Davis, SD, Ferkol T. “Hitting the target: new treatments for cystic fibrosis.” Am J Respir
Crit Care Med 2010 Dec; in press.
53. Davis SD, Rosenfeld M, Kerby GS, Brumback L, Kloster MH, Acton JD, Colin AA,
Conrad CK, Hart MA, Hiatt PW, Mogayzel PJ, Johnson RC, Wilcox SL, Castile RG.
“Multicenter Evaluation of Infant Lung Function Tests as Cystic Fibrosis Clinical Trial
Endpoints.” Am J Respir Crit Care Med 2010 Dec; in press.
54. Sleath B, Ayala G, Davis S, Williams D, Tudor G, Yeatts K, Washington D, Gillette C.
“Child and caregiver reported problems and concerns in using asthma medications.”
Journal of Asthma; 2010 Aug; 47 (6): 633-8.
55. Borowitz D, Parad RB, Sharp JK, Sabadosa KA, Robinson KA, Rock MJ, Farrell PM,
Sontag MK, Rosenfeld M, Davis SD, Marshall BC, Accurso FJ. “Cystic Fibrosis
Foundation Practice Guidelines for the Management of Infants with Cystic Fibrosis
Transmembrane Conductance Regulator-Related Metabolic Syndrome During the First
Two Years of Life and Beyond.” J Pediatr 2009 Dec;155:S106-16.
56. Borowitz D, Robinson KA, Rosenfeld M, Davis SD, Sabadosa KA, Spear SL, Michel
SH, Parad RB, White TB, Farrell PM, Marshall BC, Accurso FJ. “Cystic Fibrosis
Foundation Evidence-Based Guidelines for Management of Infants with Cystic Fibrosis.”
J Pediatr 2009 Dec;155:S73-93.
57. Stanojevic S, Wade A, Cole TJ, Lum S, Custovic A, Silverman M, Hall GL, Welsh L,
Kirkby J, Nystad W, Badier M, Davis SD, Turner S, Piccioni P, Vilozni D, Eigen H,
Vlachos-Mayer H, Zheng J, Tomalak W, Jones M, Hankinson JL, Stocks J. “Spirometry
Centile Charts for Young Caucasian Children: The Asthma UK Collaborative Initiative.”
Am J Respir Crit Care Med 2009; Sep 15;180(6):547-52
58. Leigh MW, Pittman JE, Carson JL, Ferkol TW, Dell SD, Davis SD, Knowles MR,
Zariwala MA. “Clinical and Genetic Aspects of Primary Ciliary Dyskinesia/Kartagener
Syndrome.” Genetics in Medicine 2009, Jul 11 (7): 473-87.
59. Peterson-Carmichael S, Harris WT, Goel R, Noah TL, Johnson R, Leigh M, Davis SD.
“The Association of Lower Airway Inflammation with Physiologic Findings in Young
Children with Cystic Fibrosis.” Pediatric Pulmonology 2009 May; 44(5):503-11.
60. Dellon EP, Donaldson SH, Johnson R, Davis SD; “Safety and Tolerability of Inhaled
Hypertonic Saline in Young Children with Cystic Fibrosis.” Pediatr Pulmonol. 2008;
Nov; 43(11):1100-6.
61. Davis SD, Aurora P, Eigen H, Beydon N, Lombardi E on behalf of the ATS/ERS
Working Group on Infant and Young Children Pulmonary Function Testing. “Quality
Control for Spirometry in Preschool Children (author correspondence).” Am. J. Respir.
Crit. Care Med., Jul 2008; 178: 107 - 108
62. Davis SD, Johnson RC, Flucke RL, Kisling JA, Myers TR. “AARC Clinical Practice
Guideline: Infant/Toddler Pulmonary Function Tests.” Respiratory Care. 2008 Jul; 53
(7): 929-945.
63. Davis SD, Ratjen F. “Reduced Lung Function in Cystic Fibrosis: A primary or secondary
phenotype?” (editorial); Am J Respir Crit Care Med 2008 Jul 1; 178 (1): 2-3
64. Brown DE, Pittman JE, Leigh MW, Fordham L, Davis SD. “Early Lung Disease in
Young Children with Primary Ciliary Dyskinesia.” Pediatr Pulmonol. 2008 May;
43(5):514-6.
8
65. Esther CR, Alexis NE, Clas ML, Lazarowski ER, Donaldson SH, Pedrosa Ribeiro CM,
Moore CG, Davis SD, Boucher RC. “Extracellular Purines are Biomarkers of
Neutrophilic Airway Inflammation.” Eur Respir J. 2008 May;31(5):949-56.
66. Davis SD, Brody AS, Emond MJ, Brumback LC, Rosenfeld M. “Endpoints for Clinical
Trials in Young Children with Cystic Fibrosis.” Proceedings of the American Thoracic
Society 2007; Aug 1;4(4):418-30.
67. Beydon N; Davis SD; Lombardi E; Allen JL, Arets HGM, Aurora P, Bisgaard H, Davis
GM, Ducharme F, Eigen H, Gappa M, Gaultier C, Gustafsson PM, Hall GL, Hantos Z,
Healy MJR, Jones MH, Klug B, Lodrup Carsen KC, McKenzie SA, Marchal F, Mayer
OH, Merkus PJFM, Morris MG, Oostveen E, Pillow JJ, Seddon PC, Silverman M, Sly
PD, Stocks J, Tepper RS, Vilozni D, Wilson NM, on behalf of the ATS/ERS Working
Group on Infant and Young Children Pulmonary Function Testing. “An Official
American Thoracic Society/European Respiratory Society Statement: Pulmonary
Function Testing in Preschool Children.” Am J Respir Crit Care Med 2007 Jun 15; 175:
1305-1345.
68. Davis, SD, Fordham, LA, Noah, TL, Retsch-Bogart, GZ, Qaqish, B, Yankaskas, BC,
Johnson, RC, Leigh, MW. “HRCT abnormalities reflect BALF inflammation and track
changes in early CF.” Am J. Respir Crit. Care Med 2007; 175(9):943-50.
69. Saito J, Harris T, Gelfond J, Noah T, Leigh M, Johnson R, Davis SD. “Physiologic,
Bronchoscopic and Bronchoalveolar Lavage Fluid Findings in Young Children with
Recurrent Wheeze and Cough.” Pediatr Pulmonol. 2006 Aug; 41: 709-719.
70. The ATS/ERS Working Group on Infant and Young Children Pulmonary Function
Testing Consensus Statement. (Member). “Raised volume forced expirations in infants:
guidelines for current practice.” Am J Respir Crit Care Med. 2005 Dec; 172: 1463-1471.
71. Jones M, Howard J, Davis SD, Kisling J, Tepper R. “Sensitivity of Spirometric
Measurements to Detect Airway Obstruction in Infants.” Am. J. Respir. Crit. Care Med.
2003 May; 167: 1283-1286.
72. Goldstein A, Castile R, Davis SD, Filbrun D, Flucke R, McCoy K, Tepper R.
“Bronchodilator Responsiveness in Normal Infants and Young Children.” Am J Respir Crit
Care Med. 2001 Aug; 164: 447-454.
73. Davis S, Jones M, Kisling J, Howard J, Tepper R. “Comparison of normal infants and
infants with cystic fibrosis using forced expiratory flows breathing air and heliox.” Pediatr
Pulmonol. 2001 Jan; 31(1): 17-23.
74. Jones M, Davis SD, Kisling J, Howard J, Castile R, Tepper R. “Flow Limitation in Infants
Assessed by Negative Expiratory Pressure.” Am J Respir Crit Care Med. 2000 Mar; 161:
713-717.
75. Jones M, Castile R, Davis SD, Kisling J, Filbrun D, Flucke R, Goldstein A, Emsley C,
Ambrosius W, Tepper R. “Forced Expiratory Flows and Volumes in Infants: Normative
Data and Lung Growth.” Am J Respir Crit Care Med. 2000 Feb; 161: 353-359.
76. Davis SD, Jones M, Kisling J, Castile R, Tepper R. “Density Dependence of Forced
Expiratory Flows in Healthy Infants and Toddlers.” J Appl. Physiol. 1999 Nov; 87(5):
1796 - 1801.
77. Tepper RS, Jones M, Davis SD, Kisling J, and Castile R. “Rate Constant for Forced
Expiration Decreases with Lung Growth during Infancy.” Am J Respir Crit Care Med. 1999
Sep; 160: 835-838.
9
78. Jones MH, Davis SD, Grant D, Christoph K, Kisling J, Tepper RS. “Forced Expiratory
Maneuvers in Very Young Children Assessment of Flow Limitation.” Am J Respir Crit
Care Med. 1999 Mar;159:791-795.
79. Davis SD, Jones M, Kisling J, Angelicchio C, Tepper RS. “Effect of Continuous Positive
Airway Pressure on Forced Expiratory Flows in Infants with Tracheomalacia.” Am J
Respir Crit Care Med. 1998; 158:148-152.
Review Articles:
1. Goralski J, Davis SD. “Breathing Easier: Addressing the Challenges of Aerosolizing
Medications to Infants and Preschoolers” Respiratory Medicine. 2014
2. Davis, SD. “CON: HRCT should be a routine part of CF lung disease assessment.”
Pediatr Pulmonol. 2010.
3. Davis SD, Pittman J. “Measurement of Early Lung Disease in Children with Cystic
Fibrosis.” eCysticFibrosis Review January 2009 Volume 1, Issue 5.
4. Davis SD, Rosenfeld M. “Using Diagnostic Tools in the Young Child: X-rays and
Pulmonary Function.” Pediatr Pulmonol. 2007, Suppl 30.
5. Dellon E, Davis SD. “Catch Me If You Can.” ADVANCE for Managers of Respiratory
Care. 2007; 16 (6): 34.
6. Peterson-Carmichael, S, Davis S. “Debunking the Myth.” ADVANCE for Managers of
Respiratory Care. 2007; 16(1): 63.
7. Rosenfeld M, Davis SD. “Infant Pulmonary Function Tests as Outcome Measures for
Clinical Trials.” Pediatr Pulmonol. 2006; Suppl 29: S18.2.
8. Davis, S. “Preschool Spirometry.” Pediatric Respiratory Review, 2006, 7S, S11-S13.
9. Davis, S. “Neonatal and Pediatric Respiratory Diagnostics.” Respiratory Care, 2003;
48(4): 367-385.
10. Davis S. “Clinical Utility of Heliox.” ADVANCE for Managers of Respiratory Care.
2000; 9(5): 52-56.
Editor of Series of Articles in Journal:
1. Primary Ciliary Dyskinesia and Overlapping Syndromes: series of 5 manuscripts
submitted to Proceedings of the American Thoracic Society; served as 1 of the 3 editors
2. Guidelines for Preschool Lung Function Testing: Series of 8 papers submitted as one
large manuscript to Am J Respir Crit Care Med (Refereed article 4):
Lung Function Testing in Preschool Children: The Next Frontier
Clinical Implications of Pulmonary Function Testing in Preschool Children
The Interrupter Technique in Preschool Children
The Forced Oscillation Technique in Preschool Children
Assessment of Tidal Breathing Parameters in Preschool Children
Preschool Spirometry Guidelines
The Multiple Breath Inert Gas Washout (MBW) Technique in Preschool Children
Bronchial Responsiveness Tests in Preschool Children
10
Refereed Abstracts:
1. Herrera-Camino A, Stevens J, Bendy LL, Yu Z, Slaven J, Tepper RS, Davis SD;
“Association Between Sugar Cane Burning and the Prevalence of Asthma, Atopy, and
Pulmonary Function Changes in Rural Honduran Children” Annals of ATS; 2014,
abstracts issue.
2. Assaf S, Clem C, Westerhold JR, Tepper RS, Davis SD, “Ventilation Inhomogeneity in
Children with Asthma.” Annals of ATS; 2014, abstracts issue.
3. Krupp NL, Fiscus C, Krespach M, Davis SD, “Improvement of 30 Day Asthma
Readmission Rate Through Comprehensive Coordinated Quality Improvement.” Annals
of ATS; 2014, abstracts issue
4. Cristea IC, Jalou H, Ackerman V, Davis SD, Givan DC, “Use of Polysomonography to
Assess Safe Decannulation in Children.” Annals of ATS; 2014, abstracts issue
5. Deschamp A, Pettit R, Howenstine M, Slaven J, Donaldson J, Yu Z, Davis SD, “Efficacy
and Safety of Intravenous (IV) Aminoglycoside Dosing Intervals in the Pediatric Cystic
Fibrosis Population.” Pediatr Pulmonol; 2013; Volume 48, Issue S36.
6. Donaldson SD, Samulski D, LaFave C, Wu J, Zeman K, Salazar C, Bennett WD, Davis
SD. “Sustained Effect of Hypertonic Saline on Mucociliary Clearance in CF Children
with Mild Lung Disease.”Pediatr Pulmonol; 2013; Volume 48, Issue S36.
7. Kimbell JS, Fleischman GM, Pitkin E, Davis SD, Zdanski C. “Wall Shear Stresses and
Airflow Patterns in the Upper Airway of a Child with Subglottic Stenosis: Comparisons
Before and After Airway Reconstruction with Normal Children.” Annals of ATS; 2014
8. Zariwala MA, Ostrowski LE, Loges NT, Hurd T, Leigh MW, Huang L, Wolf WE,
Carson JL, Hazucha MJ, Yin W, Davis SD, Dell SD, Ferkol TW, Sagel SD, Olivier KN,
Jahnke C, Olbrich H, Werner C, Gee HY, Otto EA, Halbritter J, Turner EH, Lewis AP,
Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Omran H, Knowles MR.
“Exome Sequencing Identifies Germline Mutations in SPAG1 as a Cause of Primary
Ciliary Dyskinesia Associated with Defective Outer and Inner Dynein Arms.” Ann Am
Thoracic Soc; 2013; in press
9. Hong Y, Neithammer M, Andruejol J, Kimbell JS Pitkin E, Superfine R, Davis SD,
Zdanski C, Davis BC. “A Pediatric Airway Atlas and Its Application in Upper Airway
Obstruction.” Ann Am Thoracic Soc; 2013; A3684.
10. Zariwala MA, Daniels ML, Leigh MW, Davis SD, Armstrong MC, Carson JL, Hazucha
M, Dell SS, Eriksson M, Collins FS, and Knowles MR. “Founder Mutation in RSPH4A
Gene Identified in Patients of Hispanic Descent with Primary Ciliary Dyskinesia.”
Gordon Research Conference: Cilia, Mucus & Mucociliary Interactions, April 7-12,
2013; Lucca (Barga) Italy.
11. Leigh MW, Chawla KK, Baker BR, Hazucha MJ, Brown DE, LaVAnge LM, Horton BJ,
Qaqish BF, Caron JL, Davis SD, Dell SD, Ferkol TW, Atkinson JJ, Olivier KN, Sagel
SD, Rosenfeld M, Milla C, Zariwala MA, Knowles MR and Genetic Disease of
Mucociliary Clearance Consortium (GDMCC). “Standardization of Nasal Nitric Oxide as
Screening Test for Primary Ciliary Dyskinesia.” Am J Respir Crit Care Med; 2012 185:
A3898
12. Leigh MW, Shapiro AJ, Pittman JE, Davis SD, Lee H, Krischer J, Ferkol TW, Atkinson
JJ, Sagel SD, Rosenfeld M, Dell SD, Milla C, Olivier KN, Knowles MR and Genetic
Disease of Mucociliary Clearance Consortium (GDMCC). “Definition of Clinical Criteria
11
for Diagnosis of Primary Ciliary Dyskinesia.” Am J Respir Crit Care Med; 2012 185:
A2483
13. Pittman JE, Lin F, Johnson R, Jones P, Davis SD. “Patterns of Infant Lung Function in
Infants with Cystic Fibrosis vs. Wheezy Infants.” Am J Respir Crit Care Med; 2012 185:
A5262.
14. Stanojevic S, Gappa M, Davis SD, Kirky J, Stocks J, Hall G. “Re-Defining Quality
Control Criteria for Spirometry in Young Children.” Am J Respir Crit Care Med; 2012
185: A2352.
15. Pittman JE, Lin F, Davis S. “Population Characteristics of Young School-Age Children
with CF.” Pediatric Pulmonology 46; Issue S34 (abstracts issue) September 2011.
16. Pittman JE, Noah HH, Calloway EH, Davis SD, Sagel SD, Accurso FJ, Knowles MR,
Sontag MK. “Early Infection with Pseudomonas aeruginosa Does Not Explain
Differences in Lung Function in Early Childhood That Persist into Adolescence in
Subjects with Cystic Fibrosis: A Replication Study.” Am J Respir Crit Care Med. 2011
(abstracts issue); in press
17. Pittman JE, LaFave CO, Coverstone A, Johnson RC, Jones P, Davis SD. “Lung Function
in Children of All Races Correlates Well with Surrogate Measures of Thorax Length.”
Am J Respir Crit Care Med. 2011 (abstracts issue); in press
18. Pittman JE, Rosenfeld M, LaFave C, Ferkol T, Sagel S, Dell S, Milla CE, Jones P,
Johnson RC, Leigh MW, Knowles MR, Davis SD, on behalf of the Genetic Diseases of
Mucociliary Clearance Consortium. “Characteristics of Primary Ciliary Dyskinesia in
Children Under 5 Years of Age.” Am J Respir Crit Care Med. 2011 (abstracts issue); in
press
19. Pittman JE, Johnson RC, Jones P, Davis SD. “Multiple Breath Washout using a Closed
(Rebreathing) System in Children with Cystic Fibrosis vs. Healthy Controls – Initial
Results.”
Am J Respir Crit Care Med. 2011 (abstracts issue); in press
20. Pittman JE, Zariwala M, Weck K, Leigh MW, Davis SD. “Respiratory Failure as Cause
of Death in an Infant with Primary Ciliary Dyskinesia.” Am J Respir Crit Care Med.
2011 (abstracts issue); in press.
21. Rosenfeld M, Davis S, Ice C, Johnson C, Oermann C, Prestridge A, Sawicki G, VirellaLowell I, Wilmott R. “Tolerability Of Denufosol For Inhalation In 2 to 4 Year Old
Children with Cystic Fibrosis.” Pediatric Pulmonology 46; Issue S34 (abstracts issue)
September 2011
22. Rosenfeld M, Farrell PM, Kloster M, Brumback L, Acton J, Colin A, Conrad C, Hart M,
Kerby G, Hiatt P, Mogayzel P, Johnson R, Castile R, Davis SD. “Association of
Physiologic Measures and Clinical Characteristics in a Multicenter Cohort of Infants with
CF.” Pediatric Pulmonology 46; Issue S34 (abstracts issue) September 2011.
23. Brumback LC, Davis SD, Kerby GS, Kloster M, Johnson R, Castile R, Hiatt PW,
Rosenfeld M. “Lung Function from Infancy through Preschool in a Cohort of Children
with CF.” Pediatric Pulmonology; Supp 33 (abstract issues), October 2010.
24. Ren CL, Kerby GS, Rosenfeld M, Mayer OH, Castile R, Hart M, Hiatt PW, Kloster M,
Brumback LC, Johnson R, Davis SD. “Analysis of the Association between Clinical
Features and Lung Function in Preschool Children with CF.” Pediatric Pulmonology;
Supp 33 (abstract issues), October 2010.
12
25. Chawla K, Hazucha MJ, Dell SD, Ferkol TW, Sagel SD, Rosenfeld M, Baker B, Davis
SD, Knowles MR, Leigh MW. Genetic Diseases of Mucociliary Clearance Consortium.
Am J Respir Crit Care Med., 2010; 181:A6726.
26. Pittman JE, Johnson RC, Davis SD. Bronchodilator Responsiveness by Infant Pulmonary
Function Testing. Am J Respir Crit Care Med., 2010; 181:A3916
27. Shapiro AJ, Davis SD, Olivier KN, Ferkol TW, Dell SD, Sagel SD, Rosenfeld M, Milla
CE, Atkinson JJ, Knowles MR, Leigh MW. Clinical Symptoms Associated with Primary
Ciliary Dyskinesia – Results of a Multi-Centered Study. Am J Respir Crit Care Med.,
2010; 181:A6728.
28. Patel KA, Davis SD, Johnson R, Esther CR. Disease Markers in the Exhaled Breath
Condensate of Infants and Preschoolers. Am J Respir Crit Care Med., 2010; 181:A3288.
29. Peterson-Carmichael SL, Johnson R, Noah TL, Davis SD. Physiologic and Inflammatory
Findings in Young Children After Respiratory Syncytial Virus (RSV) Bronchiolitis. Am J
Respir Crit Care Med., 2010; 181:A3293.
30. Ramanathan C, Davis S, Alexis N, Leigh M, Boucher R, Donaldson S. Evaluation of
Percent Solids of Lower Airway Secretions of Infants and Children with Cystic Fibrosis.
Ped Pulm Supp. 32 (abstracts issue) October 2009.
31. Pittman J, Johnson R, Davis S. Change in Pulmonary Function Following IV Antibiotics
in Infants with CF. Ped Pulm Supp. 32 (abstracts issue) October 2009.
32. Pittman J, Johnson R, Davis S. Bronchodilator Responsiveness in Infants with CF. Ped
Pulm Supp. 32 (abstracts issue) October 2009.
33. Kerby GS, Rosenfeld M, Ren CL, Mayer OH, Castile R, Hart M, Hiatt PW, Kloster M,
Brumback L, Johnson R, Davis SD. Spirometry Distinguishes Preschool Children with
CF From Healthy Controls in a Multicenter Setting. Ped Pulm Supp. 32 (abstracts issue)
October 2009.
34. Leigh MW, Ferkol TW, Dell SD, Davis SD, Knowles MR. Primary Ciliary Dyskinesia in
Children: Dichotomy in Structural Versus Functional Changes in Airways.
Am. J. Respir. Crit. Care Med., Apr 2009; 179: A3674.
35. Pittman JE, Davis SD. Spirometry in Biracial Children: Assessing Adequacy of Current
Race-Based Reference Equations. Am. J. Respir. Crit. Care Med., Apr 2009; 179: A4850.
36. Kerby GS, Rosenfeld M, Ren C, Mayer O, Castile R, Hart M, Hiatt P, Kloster M,
Brumback L, Johnson R, Davis SD. Multi-center lung function testing in preschool
subjects; Ped Pulm Supp. 31 (abstracts issue) October 2008
37. Rosenfeld M, Davis SD, Brumback L, Daniel S, Johnson R, Rowbotham R, McNamara
S, Martin S, Barlow C, Ratjen F. Inhaled 7% Hypertonic Saline is Well Tolerated in
Infants and Toddlers with CF. Ped Pulm Supp. 31 (abstracts issue) October 2008.
38. Pittman J, Calloway E, Yeatts J, Drumm M, Leigh M, Davis S, Van Rie A, Emond M,
Knowles M. Age of Pseudomonas aeruginosa Infection and Severity of Lung Disease in
Cystic Fibrosis Adolescents and Adults. Ped Pulm Supp. 31 (abstracts issue) October
2008: A332, p. 319.
39. Ayala GX, Sleath B, Davis S, Williams D, Yeatts K, Washington D; Child and caregiver
question-asking and input into asthma management regimens during pediatric visits;
International Conference on Communication in Healthcare; Oslo, Norway
40. Sleath B, Ayala GX, Williams D, Davis S, Yeatts K, Washington D; Provider question
asking about asthma controller medications during pediatric asthma visits; International
Conference on Communication in Healthcare; Oslo, Norway
13
41. Huda W, Fordham LA, Frey GD, Davis S; Effective Doses to Pediatric Cystic Fibrosis
Patients Undergoing Chest CT Examinations. American Association of Physicists in
Medicine, July 27-31, 2008
42. Pittman JE, Davis SD, Chawla KK, Brown DE, Knowles MR, Leigh MW. Primary
Ciliary Dyskinesia: Characteristics of Children under Six. Proceedings of the American
Thoracic Society; 2008, A798.
43. Dellon E, Donalson S, Johnson R, Davis S; Safety and Tolerability of Hypertonic Saline
in Infants and Young Children with Cystic Fibrosis; Pediatric Pulmonology, 2007, Suppl
30; 298.
44. Davis, S, Kerby, G, Acton, J, Castile, R, Colin, A, Conrad, C, Hart, M, Hiatt, P,
Mogayzel, P, Johnson, R, Wilcox, S, Knutzen, S, Brumback, L, Rosenfeld, M.
Feasibility, Sensitivity and Variability of Adult-Type Pulmonary Function Tests in
Infants with CF in a Multicenter, Longitudinal Trial; Pediatric Pulmonology, 2006, Suppl
29; 360.
45. Dellon E, Donalson S, Johnson R, Davis S; Safety and Tolerability of Hypertonic Saline
in Young Children with Cystic Fibrosis; Pediatric Pulmonology, 2006, Suppl 29; 283.
46. Rosenfeld M, Brumback L, Knutzen S, Acton J, Castile R, Colin A, Conrad C, Hart M,
Hiatt P, Kerby G, Mogayzel P, Johnson R, Wilcox S, Davis SD. Multicenter
Longitudinal Evaluation of Raised Volume Forced Expiratory Flows in Infants with CF is
Feasible; PediatricPulmonology, 2005, Suppl 28; 354.
47. Davis SD, Peterson-Carmichael S, Noah T, Johnson R, Abode K, Leigh M. Correlation
of Infant Lung Function and Bronchoalveolar Lavage Fluid (BALF) Data in CF Infants;
Pediatric Pulmonology, 2005, Suppl 28; 336.
48. Davis SD, Kerby G, Acton J, Castile R, Colin A, Conrad C, Hart M, Hiatt P, Mogayzel P,
Brumback L, Johnson R, Wilcox S, Wohl ME, Rosenfeld M. Creating an Infant Lung
Function Testing Network. Pediatric Pulmonology, 2004, Suppl 27; 329.
49. Davis SD, Fordham LA, Noah TL, Retsch-Bogart GZ, Qaqish B, Yankaskas BC,
Johnson RC, Leigh MW. HRCT abnormalities reflect BALF inflammation and track
changes in early CF. Pediatric Pulmonology, 2004, Suppl 27; 328.
50. Saito J, Johnson R, Noah T, Leigh M, Davis S. Correlation of Physiologic Markers
versus Flexible bronchoscopy Findings in Infants with Recurrent Wheeze and Cough.
Am J Respir Crit Care Med. 2004; 164 (7): A489
51. Davis SD, Fordham LA, Retsch-Bogart G, Noah T, Johnson R, Abode K, Leigh M.
Detecting and Tracking CF Lung Disease using HRCT and BAL in Infants. Pediatric
Pulmonology, 2002; Suppl 24: A 374.
52. Harris W, Wood R, Davis S, Retsch-Bogart G, Leigh M. Chronic/Recurrent Wheezing In
Infants And Young Children: A Bronchoscopic Study. Pediatric Research, 2000. 47:
477A
53. Tepper RS, Davis S, Jones M, Kisling J, Payne N. Changes In Full Forced Expiratory
Flow Volume Maneuvers During Bronchial Challenge Testing In Infants. Eur Respir J
1999.
54. Goldstein A, Castile R, Davis S, Filbrun D, Flucke R, Tepper R, McCoy K.
Bronchodilator Responsiveness in Infants with Cystic Fibrosis. Peds Pulmon Suppl 19:
279, 1999.
14
55. Goldstein A, Castile R, Davis S, Filbrun D, Flucke R, McCoy K, Tepper R.
Bronchodilator
Responsiveness in Normal Infants. Am J Respir Crit Care Med.
1999;195(3)pt2: A674.
56. Davis S, Jones M, Kisling J, Howard J, Tepper RS. Comparison of normal and cystic
fibrosis (CF) infants using forced expiratory flows breathing heliox. Am J Respir Crit
Care Med. 1999;159(3)pt2:A504.
57. Jones M, Castile R, Davis S, Goldstein A, Filbrun D, Kisling J, Fluck R, Tepper R.
Forced
expiratory maneuvers in normal infants: normative values. Am J Respir Crit
Care Med.
1999;159(3)pt2:A504.
58. Tepper RS, Jones M, Davis S, Kisling J, Howard J, Castile R. The Time Constant from
Forced Expiratory Flow Volume Curves Increases with Lung Growth During Infancy.
EurRespir J. 1998;12(28):155(#0204).
59. Davis S, Jones M, Kisling J, Castile R, Tepper RS. Density Dependence of Forced
Expiratory Flows in Healthy Infants. Am J Respir Crit Care Med. 1998;157(3):A470.
60. Jones M, Davis S, Kisling J, Castile R, Tepper RS. Negative Expiratory Pressure to
Assess
Flow Limitation in Infants. Am J Respir Crit Care Med. 1998;157(3):A471.
61. Tepper RS, Davis S, Jones M, Kisling J. The Effect of CPAP on Forced Expiratory
Flows in Healthy Infants. Eur Respir J. 1997; 10(25):167s(#1148).
62. Jones M, Davis S, Grant D, Christoph K, Tepper RS. Negative Pressure to Assess Flow
Limitation in Very Young Children. Am J Respir Crit Care Med. 1997;155(4)pt2:A376.
63. Davis S, Jones M, Kisling J, Angelicchio C, Tepper RS. “Effect of Continuous Positive
Airway Pressure (CPAP) on Forced Expiratory Flows of Infants with Tracheomalacia.
Am J Respir Crit Care Med. 1997;155(4)pt2:A376.
Invited Workshops:
1. NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases; September 2013
2. NHLBI Workshop: Developmental Pathways in Lung Disease; June 28-29 2012European
Respiratory Society: Preparing for the first early pulmonary intervention studies in infants
and preschool children with Cystic Fibrosis; March 2012
3. NHLBI Working Group on Data Coordinating Centers’ Best Practices; May 2011;
http://www.nhlbi.nih.gov/meetings/workshops/dcc.htm
4. European Cystic Fibrosis Society – Clinical Trials Network Consensus Conference on
Outcome Parameters in Cystic Fibrosis; March 2010; Venice, Italy.
5. Advancing Rare Diseases Research though Networks and Collaboration; July 2009;
National Institute of Health
6. Care of Patients with CF Diagnosed by Newborn Screening; July 2007; Cystic Fibrosis
Foundation
7. Preventing Respiratory Sequelae in Children Diagnosed with Cystic Fibrosis by
Newborn Screening; February 2007; European Respiratory Society; Belgium
8. Imaging Endpoints for Cystic Fibrosis Clinical Trials; September 2005.
9. HRCT Special Interest Group Conference; October 2003; North American Cystic
Fibrosis Conference
15
Teaching Record:
National/International:
2014
2014
2013
2013
2013
2013
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
Speaker, Year in Review, American Thoracic Society Conference
Cystic Fibrosis
Speaker, American Thoracic Society
Faculty Development Series Panel Discussion
Chair, Poster Discussion Session, American Thoracic Society Conference
Tools of the Trade: Modalities for Evaluating Pediatric Lung Disease
Session Chair, Scientific Symposium, American Thoracic Society Conference
Applying Novel Models and Mechanistic Approaches to Pediatric Respiratory
Disease
Speaker and Moderator, American Thoracic Society Annual Conference
Lecture: Detecting Early Lung Disease in Cystic Fibrosis: What Works?
Speaker, International Society for Aerosols in Medicine
Lecture: Challenges and Limitations for Testing Efficacy of New Aerosol
Therapies
in Young Children
Schwartz Lecturer, University of Rochester,
Lecture: Using Physiologic and Structural Endpoints to Assess Respiratory
Disease in Young Children
Invited Speaker, CHEST
Lecture: Cystic Fibrosis: The Year in Review
Speaker, U.S. Congressional Briefing
Presentation Briefing: Advances & Opportunities in Child Lung Health
26th Annual North American Cystic Fibrosis Conference Evening Symposium
Lecture: Ahead of the Curve Early Intervention in CF-Assessment of Early Lung
Disease
Speaker and Moderator, 26th Annual North American Cystic Fibrosis Conference
Lecture: Lung Function Testing in the Youngest Population
Visiting SMURRF Professor, Cincinnati Children’s Hospital Medical Center
Lecture: Choosing the Road Less Traveled: Pursuing a Career as a Pediatric
Physician-Scientist
Facilitator, American Thoracic Society Annual Conference
Poster Discussion: Pediatric Cystic Fibrosis and Primary Ciliary Dyskinesia
Speaker, American Thoracic Society Annual Conference
NIH Noon Workshop, Infant PFTs as an Endpoint in the Infant Study of Inhaled
Saline Trial
Speaker and Moderator, American Thoracic Society Annual Conference
Postgraduate course, Complications of Cystic Fibrosis
Chair, Pediatric Academic Society
Original Science Abstracts Platform Session: Asthma
Invited Speaker, Vanderbilt University Pediatric Grand Rounds
Lecture: The Changing Face of Cystic Fibrosis
16
2011
2011
2011
2011
2011
2011
2011
2011
2011
2010
2010
2010
2010
2010
Invited Speaker, CHEST
Lecture: Determining the Etiology of Non-CF Bronchiectasis
Invited Speaker, CHEST
Lecture: New Diagnostics Tools in PCD: Nasal NO, Infant PFTs, Genetic
Analysis, and High Speed Video Light Microscopy
Invited Speaker, CHEST
Pediatric Fellows Conference
Lecture: Infant PFTS
Panel Member and Speaker, The Multidisciplinary Airway Team Approach to
Challenging Pediatric Patients
NC/SC Otolaryngology & Head & Neck Surgery Annual Meeting
Invited Speaker, PCD Complications in Newborns and Very Young Children
9th Annual PCD Family day
Symposium, American Thoracic Society Annual Conference
Moderator, Pediatric Year in Review
Symposium, American Thoracic Society Annual Conference
Moderator and Speaker, Functional Modeling of the Pediatric Upper Airway
Speaker, American Thoracic Society Annual Conference Postgraduate course,
Applied Pulmonary Physiology in the Infant PFT Lab
Moderator, American Thoracic Society Annual Conference
Postgraduate course: Diagnostic Tests for the Pediatric Pulmonologist
Invited Speaker, Pro-Con Debates in CF Lung Disease: MRSA, Chest CT &
Pulmonary Maintenance Therapies (Symposium)
High Resolution CT Scans of the Chest Should be a Routine Part of CF Lung
Disease Assessment: Con
Speaker, Primary Ciliary Dyskinesia and Overlapping Syndromes
Early lung disease in young children with PCD
Chairman/Speaker, American Thoracic Society Annual Conference
Mini-Symposium: Inspiring the Next Generation of Pediatric Pulmonary
Researchers
Chairman/Speaker, American Thoracic Society Annual Conference
Postgraduate Course: Airway Resistance: Theory and Practice
Speaker, American Thoracic Society Annual Conference
Postgraduate Course: How Should We Assess Outcomes in CF?
17
2009
2009
2009
2008
2008
2008
2008
2008
2007
2007
2007
2007
2007
2007
2006
2006
2006
2006
2006
2006
2006
2005
2005
Featured Speaker, American Thoracic Society Annual Conference
Lecture: The Value of Monitoring Lung Function throughout the Pediatric Age
Moderator, American Thoracic Society Annual Conference
Mini-Symposium: Best of Pediatrics
Invited Speaker, Cystic Fibrosis Therapeutic Development Network
Lecture: Review of Current Status of Studies Restoring Airway Surface Liquid
Invited Speaker, CHEST
9th Pediatric Fellows Conference
Lecture: Pulmonary Function Testing as Applied to the Wheezing Infant
Invited Speaker, Duke Airway Biology Forum
Lecture: Infant Pulmonary Function Testing State of Art
Invited Speaker, American Thoracic Society Annual Conference, Clinical Workshop
Lecture: Implementing Infant Pulmonary Function Testing into Clinical Practice
Moderator and featured speaker, American Thoracic Society Annual Conference
Lecture: Clinical and Research Outcome Measures of CF Lung Disease
Invited Speaker, Cincinnati Children's Hospital
Lecture: Infant PFTs as a Clinical Outcome Measures: Are we there yet?
Invited Speaker, CHEST
9th Pediatric Fellows Conference
Lecture: Pulmonary Function Testing as Applied to the Wheezing Infant
Invited Speaker, North American Cystic Fibrosis Conference Symposium
Lecture: Using Diagnostic Tools in the Young Child: X-rays and Pulmonary Function
Facilitator, American Thoracic Society Annual Conference
Thematic Poster Session: Cystic Fibrosis: Translational and Clinical Science
Invited Speaker, American Thoracic Society Annual Conference
Lecture: Infant Pulmonary Function Testing: Is There a Role in Early Wheezing?
Session Chair, American Thoracic Society Annual Conference
Postgraduate Course, Lung Function Testing in Young Children: Clinical and
Research Applications
Invited Speaker, Indiana University School of Medicine
Lecture: Detecting Early Cystic Fibrosis Lung Disease
Co-Chair and Speaker, North American Cystic Fibrosis Conference
Symposium: Measuring Early CF Lung Disease
Invited Speaker, North American Cystic Fibrosis Conference
Course: Introduction to CF Clinical Research
Lecture: Data and Specimen Banking
Invited Speaker, CHEST
Lecture: Advances in Infant Pulmonary Function Testing
Invited Speaker, CIPP (Congress of International Pediatric Pulmonology)
Postgraduate Course, Assessment of Lung Function in Preschool Children
Lecture: Preschool Spirometry
Moderator and Featured Speaker, American Thoracic Society Annual Conference
Lecture: Recent progress and clinical applicability of infant lung function testing
Sunrise Seminar, American Thoracic Society Annual Conference
Lecture: Incorporating Infant PFTs into Clinical Practice
Invited Speaker, FOCUS on Respiratory Care & Sleep Medicine Conference
Lecture: Evaluating Respiratory Function in Children
Moderator and Featured Speaker, American Thoracic Society Annual Conference
Lecture: Advances in Assessment and Treatment of CF Lung Disease
Facilitator, American Thoracic Society Annual Conference
Thematic Poster Session: Measurement Techniques for Pediatric Lung Disease
18
2004
2003
2002
2000-02
1998
1996
European Respiratory Society School Course on Assessment and Interpretation of
Infant Lung Function
Nice, France
Lectures: The Infant Pulmonary Lab, Collins Medical
Clinical Usefulness in Individual Infants?
Full Forced Expiratory Maneuvers
Sunrise Seminar, American Thoracic Society Annual Conference
Lecture: Implementation of Infant Pulmonary Function Testing As An Integral Part of
the Pediatric Pulmonary Practice
Respiratory Care Journal Conference
Keystone, Colorado
Lecture: Diagnostics
Infant PFT Round table at the NACF Conference
Moderator
Pediatric Clinical Fellows Session at the CF Conference:
Moderator.
Pediatric Clinical Fellows Session at the Cystic Fibrosis Conference
Lecture: Follow-up of a Patient with Cystic Fibrosis who required Mechanical
Ventilation as an Infant
Grand Rounds:
2014
Grand Rounds, Children’s Hospital at Montefiore
The Changing Face of Cystic Fibrosis
2013
Grand Rounds, East Tennessee State University
The Changing Face of Cystic Fibrosis
2012
Grand Rounds, Riley Hospital for Children
The Changing Face of Cystic Fibrosis
2007
Grand Rounds, Wilmington AHEC
Obstructive Sleep Apnea
2005
Grand Rounds, UNC
Morbidity and Mortality; Enteropatheca Dermatitis and Cystic Fibrosis
2004
Grand Rounds, Moses Cone Hospital
Pulmonary Function Testing in Infants and Young Children
2004
Grand Rounds, UNC
Infant Pulmonary Function Testing
2002
Grand Rounds, Wake Medical Center
Obstructive Sleep Apnea
2002
Grand Rounds, Moses Cone Hospital
Obstructive Sleep Apnea
2001
Grand Rounds, Rex Hospital
Infant Pulmonary Function Tests as a Clinical Research Tool
Regional/University:
2013
Section of Adult Pulmonology
19
2012
2012
2012
2012
2011
2010
2007-11
2007
2005
2004
2003-11
2001
2001-04
2001
2000
2000
1997
Identifying, Validating and Using Structural and Physiologic Endpoints to
Assess Respiratory Disease in Young Children
Department of Cellular and Integrative Physiology
Research Seminar: Using Physiologic and Structural Endpoint to Assess
Respiratory Disease in Young Children
Riley Hospital for Children Pediatric Conference
Lung Function Testing in Children
Morris Green Scholars Noon Lecture
Successful Manuscript Preparation
Indiana ALA Board Meeting
Evaluating Early Lung Disease in Young Children with Cystic Fibrosis
UNC Annual Fellows Symposium
Successful Manuscript Preparation
UNC Cystic Fibrosis Research Seminar
Developing Outcomes in Young Children with Lung Disease
UNC Pediatric Pulmonology Physiology Series
Infant Lung Function Testing
UNC Faculty Workshop
Faculty Development and Mentoring
UNC Pediatric Noon Conference
Pediatric Lung Function Testing
UNC Cystic Fibrosis Clinical Research Seminar
Detecting Early CF Lung Disease: HRCT of the Chest Multiple Breath
Washout
UNC Pediatric Pulmonary Fellows’ Conference
Pediatric Spirometry
UNC Cystic Fibrosis Clinical Research Seminar
High Resolution Computed Tomography with Controlled Ventilation
UNC Pediatric Noon Conference
Obstructive Sleep Apnea
UNC Pediatric Pulmonary Fellows’ Conference
Infant Lung Function Testing
UNC Neonatology Fellows’ Conference
Infant Pulmonary Function Tests
UNC Cystic Fibrosis Clinical Research Seminar
Infant Pulmonary Function Tests
Respiratory Care Department’s Continuing Education for the Healthcare
Provider
Mechanical Ventilation and the Asthmatic Patient
Course Director:
2004-08
Pediatric Pulmonology Rotation
Director of the Residents, Medical Students
Research Mentor:
2014- present Shawn Ahlfeld, Assistant Professor, Neonatology
Project: Long term follow-up of children with chronic lung disease of prematuriy
20
2013-present
Ashley Deschamp, Pediatric Pulmonary Fellow
Project: Assessing Stool Microbiome in the Young Infant with CF
2013-present Kirsten Kloepfer, Assistant Professor, Pediatric Pulmonology, Allergy, Sleep
Project: Viral Microbiome in Infants of Mothers with Asthma
2012-present Tonia Gardner, Pediatric Pulmonary Fellow
Project: Aminoglycoside Nephrotoxicity in Pediatric Cystic Fibrosis Patients
2011-present Ioana Cristea, Pediatric Pulmonary Fellow/Faculty
Projects: 1. Long Term Outcome of Children with BPD Who Were Discharged
on Home Positive Pressure Ventilation
2. Improving Communication with PCPs caring for CF patients
2010-2014
Jennifer Goralski, Pulmonary fellow/Faculty
Projects: Eosinophilic Esophagitis in CF; Aerosol Treatment in Children
2008-11
Kavita Patel, Pediatric Pulmonology Fellow
Project: Disease Markers in Exhaled Breath Condensate (EBC) of Infants
2008-present Adam Shapiro, Pediatric Pulmonology Fellow, Assistant Professor (Montreal)
Project: Primary Ciliary Dyskinesia
2007-10
Chandar Ramanathan; Pediatric Pulmonology Fellow
Project: Evaluating Regulators of Mucus Clearance in Childhood Lung
Disease
Grant Support: Cystic Fibrosis Foundation Fellowship Grant (1st2nd 3rd year)
2007-present Jessica Pittman; Pediatric Pulmonology Fellow
Projects: 1. Spirometry in Biracial Children – Assessing the Adequacy of
Current NHANES Race-Based Reference Equations
2. Early Onset and Progression of Primary Ciliary Dyskinesia Lung Disease
Prior to 10 Years of Age
2007-present Ruchika Goel; Masters of Public Health Student (Practicum)
Project: Physiologic, Inflammatory and Airway Remodeling Findings in Infants
with Cystic Fibrosis
2005-07
Elisabeth Dellon; Pediatric Pulmonology Fellow
Project: Hypertonic Saline in Infants and Young Children with Cystic Fibrosis
2004-present Stacey Peterson-Carmichael; Pediatric Pulmonology/ICU Fellow
Projects: 1. Effect of Inhaled Corticosteroids on Infant Pulmonary Function
after RSV Bronchiolitis
2. Physiologic, Inflammatory and Airway Remodeling Findings in Infants with
Cystic Fibrosis
Grant Support: Medimmune Pediatric Fellowship Grant
2002-05
John Saito; Pediatric Pulmonology Fellow
Project: Physiologic, Bronchoscopic and Bronchoalveolar Lavage Fluid
Findings In Young Children with Recurrent Wheeze and Cough
Residency Class Advisor
2004-07
Pediatric Resident Class
2001-04
Pediatric Resident Class
Scholarly Oversight Committee; PhD Thesis Reviews:
2012
Fiona Healy, MB, BCh, ZBAO (Hons), MRCPI; University College Dublin
Lung Structure and Function in Infants with Congenital Diaphragmatic Hernia
21
2009
2008
2004-07
Deidre Washington, PhD; University of North Carolina at Chapel Hill
Thesis: The Effect of Patient Race on Patient-Provider Communication with
Pediatric Asthma Patients
Catherine Gangell, BsC; University of Western Australia
Thesis: Evaluation of the Forced Oscillation Technique for Clinical
Assessment of Young Children with Cystic Fibrosis
Kristy Herman; Neonatology Fellow
Attending on Clinical Service
I attend the clinical service 4 weeks annually. During these weeks, I give lectures to the
residents and medical students. Lists of these lectures are below:
 Lung function Testing
 Cystic Fibrosis: Pathophysiology and Management
 Evaluation of the Noisy Breathing Infant
 Evaluation of the Infant with Recurrent Wheeze and Cough
 Chronic Cough
Grants:
Ongoing Research Support:
SHIP14K0 (Rosenfeld, Ratjen, Davis, PI)
11/28/2011CFF
$141,547
Multicenter study evaluating efficacy of hypertonic saline in preschoolers
1R01HL116211-01 (Davis/Ferkol/Ranganathan)
9/26/2012-06/30/2016
NIH
$1,995,535
Viral Pathogenesis of Early Cystic Fibrosis Lung Disease
The goal is to determine the frequency of respiratory virus infections and their impact on the
evolution of endobronchial bacterial infection and inflammation in CF infants.
5 R01 HL105702-02 (Davis/Voynow/Cotton/Poindexter (PI))
9/1/2011-8/31/2015
NIH/NHLBI
Gastrin-Releasing Peptide and Bronchopulmonary Dysplasia
Two center study evaluating gastrin-releasing peptide as a predictor of pulmonary morbidity
in bronchopulmonary dysplasia
Role: PI
RFA HL 10-017 (R01) (PIs: Davis, Zdanksi, Superfine)
10/1/2010 -9/30/2014
NIH/NHLBI
$2,600,000 Direct
Predictive Modeling for Treatment of Upper Airway Obstruction
We hypothesize that a functional computational model that simulates the mechanical and
aerodynamic behavior of the upper airway in infants with Pierre Robin sequence and
laryngeal lesion (e.g. subglottic stenosis) can be used as an effective diagnostic and treatment
planning tool, reducing failures of initial treatment and avoiding potentially unnecessary
future complications and interventions
22
5 U54 RR019480-02 (Knowles-PI)
8/6/2004 – 7/31/2014
NIH (National Center for Research Resources)
$6,225,000 (Direct and Indirect)
Genetic Disorders of Mucociliary Clearance
A five center consortium evaluating rare diseases of the airways, which involve defects in
mucociliary clearance.
1U01HL092931-01 (Rosenfeld-PI; Davis-PI)
10/1/08-7/31/14
NIH/NHLBI
$83,692
Subcontract with Childrens Hospital Regional Medical Center (Davis – PI)
Infant Study of Inhaled Saline in Cystic Fibrosis (ISIS)
This multiple center study evaluates 7% HS inhaled twice daily for 48 weeks versus twice
daily inhalation of normal saline (placebo) in CF infants (4 to 15 months at enrollment).
ISIS07KO (Davis-PI; Rosenfeld-PI)
10/01/2007 – 9/30/14
Cystic Fibrosis Foundation
$836,587
Infant Study of Inhaled Saline in Cystic Fibrosis (ISIS)
This multiple center study evaluates 7% HS inhaled twice daily for 48 weeks versus twice
daily inhalation of normal saline (placebo) in 150 CF infants (4 to 15 months at enrollment).
DAVIS08Y2 (Davis-PI)
1/1/14-12/31/14
Cystic Fibrosis Foundation Therapeutics, Inc
$39,122
Infant and Preschool Pulmonary Function Testing Core
The goal of this project is to ensure that TDN sites are performing infant and preschool lung
function testing as outlined in the protocols and Standard Operating Procedures and that the
data collected is of research quality.
Completed Research Support:
RETSCH09Y0 (Retsch-Bogart – PI) 1/1/11-12/31/11
Cystic Fibrosis Foundation Therapeutics, Inc.
Therapeutic Development Center
Role: Co-PI
$160,000
1 P50 HL 084934-01 (Boucher-PI)
9/15/12006– 7/31/2011
1.61 calendar
NIH/NHLBI
$2,174,432
SCCOR in Host Factors in Chronic Lung Disease
The purpose of this study is to assess host defense factors contributing to exacerbations of
disease in COPD and CF.
NC TraCS Institute
5/1/09-7/31/10
Role: PI
Validation of the Mulitple Breath Washout Device for Asssessment of Pediatric Lung Diseases
1R13HL105073-01 (Davis-PI)
9/30/2010-10/1/2010 Role: PI
NHLBI
$15,000
Primary Ciliary Dyskinesia and Overlapping Syndromes Conference
23
Genentech, Inc. (Davis-PI)
1/1/08-12/31/09
.24 Calendar
Consulting Agreement for Protocol Z4240g
$11,000
Dr. Davis acted as consultant for oscillometry and spirometry testing in preschool children.
Genentech, Inc. (Davis-Site PI)
6/24/08-6/23/11
.84 Calendar
Z4240g A Phase IV, Multicenter, Randomized, Double Blind, Placebo Controlled Trial of
Pulmozyme in 3- TO 5-Year-Old Patients with CF
$43,283
This was a Phase IV, multicenter, randomized, double-blind, placebo-controlled trail
designed to evaluate the effect of study drug on pulmonary function, health related quality of
life (HRQOL), and respiratory symptoms in 3 to 5 year old children with Cystic Fibrosis.
R01 HL069837 (Sleath -PI)
8/1/2005 – 7/31/2009
1.04 calendar
NIH
$280,477
Children and Asthma: Communication and Outcomes
The project is focused on a neglected area within children's health services research, the
relationship between provider-child-caregiver communication during pediatric asthma visits
and treatment adherence.
Cystic Fibrosis Clinical Research Grant
7/1/05-6/31/08
9.3%
Cystic Fibrosis Foundation
$18,597 (1st year); $92,077 (3 years)
Spirometry as an Outcome Measure in Preschool Children with CF
Kerby04A0
An 8 center study evaluating lung function measurements longitudinally in preschoolers with
cystic fibrosis and age-matched controls
Role Co-PI
Cystic Fibrosis Foundation
A Pilot Study to Evaluate the Tolerability of Inhaled
Hypertonic Saline in Infants with Cystic Fibrosis
Role: Co-PI
7/07-6/08
$20,000
7%
Cystic Fibrosis Foundation
2/1/05-1/31/07
15%
Cystic Fibrosis Clinical Research Grant
$47,365 (1st year); $69,234 (2
years)
Hypertonic Saline in Infant and Young Children with CF
A single center study assessing the safety of hypertonic saline in infants and young children
with cystic fibrosis
Role PI
DAVIS08Y2
2/1/03-1/31/07
30%
Cystic Fibrosis Foundation
$75,190 (last year) $1,000,000 (over 3 years)
Evaluation of Pulmonary Function Tests from Raised Lung Volumes as Outcome Measures
for Clinical Trials in Infants with Cystic Fibrosis
A 10 center study evaluating longitudinal changes of infant lung function testing over 1 year
in infants with cystic fibrosis
Role PI
24
Cystic Fibrosis Clinical Research Grant
7/1/02-6/30/05
Cystic Fibrosis Foundation
$80,000
Detecting Early, Reversible CF Lung Disease on HRCT
This study is correlating changes on HRCT of the chest to bronchoscopy findings.
Role PI
Harry Shwachman Clinical Investigator Award
7/1/00-6/30/03
Cystic Fibrosis Foundation
$225,000
Physiologic and BALF Markers of Early CF Lung Disease
This study is investigated early markers of cystic fibrosis lung disease noted on infant lung
function testing and bronchoscopy.
Role: PI
Thomas H. Davis Fellowship Award
7/1/00-6/30/02
American Lung Association
$60,000
Physiologic Versus Bronchoscopic Markers in Wheezy Infants
This study correlated physiologic markers on infant lung function testing to bronchoscopy
findings.
Role: PI
Cystic Fibrosis Foundation Clinical Fellowship Grant
7/1998-6/1999
Density Dependence of Maximal Flows in CF Infants
$55,000
Principal Investigator: Davis
Sponsor: Robert S. Tepper, MD, PhD
Cystic Fibrosis Foundation Clinical Fellowship Grant
7/1997-6/1998
Principal Investigator: Davis
Sponsor: Howard Eigen, MD $31,400
Cystic Fibrosis Foundation Clinical Fellowship Grant
7/1996-6/1997
Principal Investigator: Davis
Sponsor: Howard Eigen, MD
Professional Service:
Committees:
International/National:
2014-present Board of Directors
American Thoracic Society
2014-present Council, Member for Pulmonology
Society of Pediatric Research
2014-present Committee member, NIH sponsored AsthmaNet DSMB
2013
NHLBI Ad Hoc Reviewer; Special Emphasis Review Panel
2013-present Research Advocacy Committee
American Thoracic Society
2012-present Midwest Society for Pediatric Research
Member
2010
Faculty Member
Seventh Annual Respiratory Disease Young Investigators' Forum
25
2009-11
2007-present
2005- 11
2003-05
2005-08
2003-04
2000-present
Pediatric Program Committee
American Thoracic Society
Pediatric Chair and Chair Elect
Pediatric Planning Committee
American Thoracic Society
Member
Pediatric Program Committee
American Thoracic Society
Member
Infant/ Preschool PFT Standardization Taskforce
American Thoracic Society
USA Co-Chair
National Resource Center Committee
Therapeutic Development Network, Cystic Fibrosis Foundation
Chair
Pediatric Assembly Nominating Committee
American Thoracic Society
Member
Outcomes for Young Children with CF Working Committee
Therapeutic Development Network, Cystic Fibrosis Foundation
Co-Director
Indiana:
2012-present Department of Pediatrics Promotion Committee for Tenure
2011-present Morris Green Scholar Executive Committee
UNC:
2007-11
Faculty Development Committee, Department of Pediatrics
Chair
2007-11
Promotions Committee
Department of Pediatrics
Member
2005 & 2007 Department of Pediatrics Evening of Scholarship
Judge of Clinical Abstracts
2003-05
Pediatric Clerkship Advisory Committee
Department of Pediatrics
Member
2002-08
Pediatric Intern Selection Committee
Department of Pediatrics
Member
2001-02
Promotions Committee
Department of Pediatrics
Member
26
Professional Membership:
American Academy of Pediatrics
American Thoracic Society
North Carolina Medical Society
Society of Pediatric Research
Other UNC Administrative Activities:
2001-07
2001-11
2001-11
Resident Advisor
Department of Pediatrics
Associate Director of PFT Laboratory
Medical Director of Infant PFT Laboratory
Reviewer:
American Journal of Respiratory and Critical Care Medicine
Archives of Pediatric Adolescent Medicine
Austrian Science Fund
Chest
European Journal of Applied Physiology
European Respiratory Journal
Health Research Board of Ireland
Health Services, Public Health Research Board Medical Research
Council(England)
Journal of Applied Physiology
Journal of Cystic Fibrosis
Lancet
New England Journal of Medicine
The Journal of Pediatrics
Pediatric Pulmonology
Pediatric Research
Respiratory Physiology and Neurobiology
Thorax
27
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