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Calendar For information on the events or to make reservations, please call one of the DRI Foundation offices listed below. Real Women - Shaping Style Florida April 30, 2006 Fashion Show Innovations will present an upbeat, choreographed runway fashion show, featuring beauty and style for all sizes, designer showcase participants, guest appearances, a celebrity host and dinner, to be held at the Sheraton Bal Harbour. Long Island Children’s Best Hope For A Cure May 4, 2006 The fifth annual event will be held at Jericho Terrace and includes dinner, dancing, plus a live and silent auction. Long Island Cycle for Lanie Bike-A-Thon May 7, 2006 Held in memory of Helaine White, this 15-mile bike-a-thon will be held in five boroughs of New York City and includes a group picnic. Don Strock Diabetes Golf Classic Florida May 17, 2006 Former Miami Dolphin and Head Coach of the FIU Golden Panthers, Don Strock hosts this 18-hole golf classic, followed by a cocktail reception, dinner, and auction at the Miccosukee Golf and Country Club. New York D.R.E.a.M.S. in the city May 18, 2006 To be held at The West Side Loft, the inaugural event will feature fabulous food, cocktails, funky music and a silent auction. This year's theme celebrates the international spirit of cuisine and collaboration at the DRI. Feast Among the Grapes Florida June 3, 2006 South Florida's premier food and wine tasting event to be held at the Radisson Hotel Miami will also feature specialty drinks, an extensive silent auction, live music, dancing and more. South Shore Sweethearts Long Island Tennis Tournament July 8-16, 2006 Celebrating 30 years of success, this tennis tournament will be held at Sportime at Atlantic DRIfocus Diabetes Research Institute National Foundation Office 3440 Hollywood Blvd. Suite 100 Hollywood, FL 33021 www.diabetesresearch.org DRIfocus Beach Tennis Club and will feature 16 divisions, including men's pro/am, women's round robin, and mixed doubles. is a publication of the Diabetes Research Institute Foundation. Spring 2006/Volume 34, Issue 2 Glen Cove Police Benevolent Long Island Association Golf Outing June 26, 2006 The third annual event will feature an afternoon of golf at the City of Glen Cove Golf Course. Editor Lori Weintraub, APR Rod Gilbert Golf Tournament Long Island August 2006 To be held simultaneously at two locations, Pine Hollow Country Club and Mutton House Country Club, this event includes an afternoon of golf followed by an awards dinner and a silent auction. Key West Poker Run Florida September 15-17, 2006 Phil Peterson will once again host his annual motorcycle run that starts in Miami and finishes in Key West for South Florida's biggest biker party weekend of the year. Kids Party for a Cure Long Island September 30, 2006 To be held at the New York Hall of Science, the event will feature magicians, clowns, dancers, thousands of interactive exhibits, and the world's largest playground. Kids Party for a Cure Florida October 14, 2006 Based on the success of its sister event in Long Island, the inaugural Florida event will be held at the BankUnited Center in Coral Gables. Open to kids of all ages and adults, the event will feature circus entertainment, tunes by DJ Irie – the Miami Heat's official deejay, fun foods, an auction, raffle prizes and more. New York Research Update New York October 21, 2006 This day-long conference at the Grand Hyatt Hotel will feature presentations by the world's leading scientists. Contributors Laurie Cummings Natasha Norris Barbara Olack Lauren Schreier Mitra Zehtab, M.D. DRIfocus Diabetes Research Institute Foundation Spring 2006 / Volume 34, Issue 2 www.diabetesresearch.org Miami • New York • Long Island • California • Washington, D.C. Design Franz Franc Design Group Inc. Photography Jenny Abreu Patty Daniels Claude Zick Foundation Staff & Volunteers The Diabetes Research Institute Foundation supports the Diabetes Research Institute at the University of Miami Leonard M. Miller School of Medicine, whose mission is to develop and rapidly apply the most promising research to treat and cure those now living with diabetes. To obtain additional information or request copies of DRIfocus, please call (800) 321-3437 or e-mail [email protected]. Diabetes Research Institute Foundation National Office 3440 Hollywood Boulevard, Suite 100 Hollywood, FL 33021 Phone: (954) 964-4040 Fax: (954) 964-7036 Northeast Regional Office 150 East 58th Street, 16th Floor New York, NY 10155 Phone: (212) 888-2217 Fax: (212) 888-2219 Long Island Regional Office 45 Glen Cove Road Greenvale, NY 11548 Phone: (516) 621-8804 Fax: (516) 621-8501 California Regional Office 6624 Melrose Avenue Los Angeles, CA 90038 Phone: (323) 857-0080 Non-Profit US Postage PAID Diabetes Research Institute Foundation Global Research Alliance Created to Cure Diabetes Diabetes Research Institute Federation is the most aggressive effort ever assembled to conquer the disease The Diabetes Research Institute at the University of Miami has brought together the world's premier diabetes research centers to launch an unprecedented assault on type 1 diabetes. The new Diabetes Research Institute Federation (DRI Federation), comprised of eight research facilities spanning seven countries, is the only global collaboration of its kind that unites the efforts of leading researchers to concentrate solely on curing diabetes through islet transplantation and other insulin replacement therapies. The centers that encompass the DRI Federation thus far are: the Diabetes Research Institute at the University of Miami in Miami, Florida; University of Robin and Barry Gibb Reunite for the DRI (Article on page 10) address service requested An unforgettable performance at the 32nd annual Love and Hope Ball. Kyoto in Kyoto, Japan; University of Alberta in Edmonton, Canada; Hospital San Raffaele in Milan, Italy; Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT) in Palermo, Italy; The Hospital Universitari Bellvitge-Islet Transplantation Unit (UTIP-HUB) in Barcelona, Spain; Karolinska Institutet in Stockholm, Sweden; and D-Cure in Israel. While scientific collaboration is not new, the size and scope of this formal alliance combined with its prioritization of cure-focused research differs dramatically from anything ever assembled in the global research community. The participating centers will work with DRI's many research teams to accelerate diabetes research using an integrated, translational approach that's designed to bring promising findings to patients more quickly than ever before. The DRI Federation extends the research philosophy that drives all of the DRI's activities: to bring together the finest minds to find a cure for those now living with diabetes. The establishment of the DRI Federation expands the DRI's many research initiatives by joining together centers that have been selected for their research excellence. (continued on page 6) Foundation Receives Multiple Million-Dollar Gifts Sterns Contribute Additional $2.5 Million for Fast Track Center When Tom and Denise Stern first learned about the Diabetes Research Institute six years ago, they were initially struck by the outpouring of support and compassion from everyone they met. Their daughter Samantha, now 8 years old, had just been diagnosed with type 1 diabetes at the young age of 22 months, and the professionals at the DRI provided them with the much-needed guidance and information for her day-to-day care and management. Dealing with the disease was certainly a necessity, but the Sterns' ultimate priority was to find a cure, and they quickly sought out the most promising research. Their search eventually brought them full circle to Miami, to a research center at the forefront of diabetes. As they became more familiar with the DRI, they were even more impressed by its longstanding philosophy. Not only did the scientists have an unparalleled urgency to cure the disease, but also an allegiance to worldwide collaboration to foster accelerated research progress. After becoming increasingly involved in the organization and chairing several events, such as the New York Research Update, the (continued on page 4) A Message from the Chairman Dear Friends, In this issue of DRIFocus we report on some extraordinary news - the formation of an unprecedented global research partnership, the receipt of several million-dollars gifts, a reunion of two legendary musicians for one of our events, and so much more. It is a very exciting time for all of us at the Diabetes Research Institute and Foundation, and we are grateful for the opportunities that have come our way. As many of you know, the DRI was built with one singular mission - to find a cure for those living with diabetes. We have been diligently working toward this goal by creating a cure-focused research program and assembling a multidisciplinary team of scientists. Now, the creation of the worldwide DRI Federation ushers in a significant phase, where investigators can pool their respective expertise and focus on key research areas. Foundation Appoints New Staff to Continue Momentum For every family affected by diabetes, this represents a huge leap toward our ultimate goal. The bringing together of some of the most brilliant scientists working in this field is truly an historic feat, and we have great expectations for what will be accomplished. performed a private concert at our Love and Hope Ball in February. The evening's guests were treated to an unforgettable performance that could not be experienced elsewhere. We extend special thanks to the Love and Hope committee, who spent endless time and energy to make the event such a success. The DRI's sense of urgency is clearly apparent, as evidenced by this latest initiative. Consequently, the Foundation continues to attract contributors who are serious, passionate, and committed to finding a cure, like the Sterns, who have given generously of their time and resources, and Rick Puente, who can sense the DRI's dedication and is compelled to support this unique program. Each of the Foundation's events would not be possible without the dedicated group of volunteers who make them happen. We thank each and every one of you for your tireless efforts. Your results speak volumes about what can be achieved by those who are committed to a mission. These recent gifts are a testament to the direction we are taking to change the futures of those who live with this disease. We are extremely grateful for these contributions and for the support of all of our donors. We are also deeply appreciative for the friendship of Barry and Robin Gibb of the Bee Gees, who By working together, we are accomplishing great things for those we love. Thank you again for all that you do to support this organization. Sincerely, Marc S. Goodman Foundation Donors Recognized Awards from the DRI Foundation’s Cycle of Discovery series were recently presented to donors who made major gifts during 2005-2006. The award program corresponds with the Foundation’s cumulative giving designations. 1. 3. 2. DONOR LEVEL 5. Benefactors Founders Grand Founders Distinguished Humanitarians Governors’ Society Leadership Council Chairman’s Council Visionaries 6. 4. AWARD $25,000+ $50,000+ $100,000+ $250,000+ $500,000+ $1,000,000+ $5,000,000+ $10,000,000+ Query Hypothesis Exploration Realization Translation Perpetuation Validation Innovation 1) The DRI's Luigi Meneghini, M.D. (right) presents Exploration to Walter Lieber and Sherrie Garfield of the Joseph and Sherrie Garfield Foundation, Grand Founder. 2) Jill and Allen Greenwald, Grand Founders, receive Exploration. 3) Grand Founders Abel, Fana, Javier and Andria Holtz accept Exploration. 4) Robert A. Pearlman, DRIF president and CEO, presents Vicki and Fred Modell with Exploration on behalf of the Jeffrey Modell Foundation, Grand Founder. 5) Frank Sciame, Jr. of F.J. Sciame Construction Co., Inc., Grand Founder, accepts Exploration from Pearlman. 6) Natalie and Harry Olstein accept Query on behalf of the Olstein Family Foundation for Brooke Goldfarb, Benefactor. 2 Deborah L. Chodrow Steven J. Fishman The Diabetes Research Institute Foundation is pleased to announce the appointment of Deborah L. Chodrow as senior vice president, and to welcome several new staff members to the organization. Deborah most recently served as vice president of major gifts since joining the Foundation in January of 2003. She has been responsible for spearheading the organization’s efforts to identify, inform and involve those individuals who can participate in the Foundation's mission through major contributions. Over the last three years, the DRI Foundation has increased revenue more than 50 percent. In addition to her current responsibilities, she will also oversee its regional offices in Florida, New York City, Long Island and California. Deborah has more than 20 years of high-level fundraising experience. Prior to joining the DRI Foundation, she spent 17 years in senior management positions at the American Friends of the Hebrew University, supervising major gifts programs and regional operations from the national office in New York, as well as directing fundraising and leadership development activities in the Southeast. During her tenure, she was professionally responsible for the American Friends’ major gift portion of The Hebrew University's International Capital Campaign, which raised over $600 million two years ahead of plan. Prior to that, she served in various positions with the National United Jewish Appeal (now United Jewish Communities). “I continue to be inspired by the extraordinary commitment of the Foundation’s leadership combined with the intense determination of the DRI’s faculty to find the cure for diabetes. The DRI Foundation is uniquely positioned to provide the critical funding the DRI needs to develop new research ideas that will ultimately benefit people living with diabetes. I look forward to working closely with our dedicated regional leadership and professional team to advance the DRI’s progress by increasing the Foundation’s fundraising success to new levels,” said Deborah. Shari F. Albert Steven J. Fishman has also joined the organization as senior vice president. Steve had been a member of the Foundation's national board since 1995, most recently serving as treasurer, and has made a tremendous contribution to the organization as a volunteer. He has now joined the Foundation in a professional capacity and will be responsible for developing new fundraising sources, such as corporate and Internet giving, as well as overseeing financial areas and working closely with the organization's chief financial officer. A successful business entrepreneur, Steve has developed several lucrative companies in diversified areas. He is a 35-year veteran of the food industry and most recently owned a food brokerage company, representing seafood companies in the US, Chile and China. He was also actively involved in the sales and marketing of a gourmet appetizer company in Chicago. In 2002, Steve saw a need for senior citizens to have better access to lower price prescription drugs and started up multiple mail order companies. DiscountGenerics.com continues to be one of the lowest price mail order pharmacies, offering more than 1,000 different generic-only medications all from the US. “I’m motivated by all the young heroes that have lived with diabetes for most of their lives. It is my hope that I can be a part of finding the cure and become their hero,” Steve stated. “With continued funding from the DRI Foundation, I know the Diabetes Research Institute will be successful in its mission and ultimately benefit all people living with diabetes,” he said. Appointed director of the Long Island region, Shari Fleschner-Albert will be responsible for spearheading the region's fundraising activities, developing targeted programs for donor cultivation, and aligning the area's strategies with the Foundation’s national development objectives. Shari brings to the Foundation almost two decades of professional fundraising and communi- 3 Cristina Spathis cations experience, having held high-level positions at several national not-for-profit organizations. Throughout her career, she has successfully implemented targeted fundraising strategies to cultivate major prospects, create special events, develop key marketing and advertising programs, and organize lay leadership groups. She most recently served as executive director of American Friends of Herzog Hospital, the U.S. fundraising arm for the third largest hospital in Jerusalem, Israel, and the country's foremost center for geriatric and mental health care. Prior to that position, she was vice president for marketing and communications for the Israel Humanitarian Foundation from 1998 to 2003. She began her career in the development field with American Technion Society, where she worked for seven years as coordinator, and subsequently as associate director of the National Programs Department. Cristina Spathis joins the Long Island office as director of special events. Cristina will be responsible for developing and managing the Foundation's fundraising events, working with volunteer leadership on event logistics and donor cultivation, and spearheading other activities to support the organization's fundraising objectives. Cristina has significant experience in all aspects of event planning, marketing and communications, sales, and client services. She most recently served for over five years as manager of membership and communications for BritishAmerican Business, Inc., New York's premier British business organization, where she managed and worked on the development of numerous events ranging from seminars to black tie gala events. Prior to this position, she was U.S. marketing/events coordinator for Lloyd's of London in New York. She also spent several years in investor and media relations, working for Edelman Worldwide and Dewe Rogerson, Inc., respectively. Sterns Contribute Additional $2.5 Million for Fast Track Center A Holistic Approach, Planning Time and Careful Consideration: The Essential Elements of Estate Planning (continued from page 1) Sterns made their first gift of $1 million to support the cutting-edge projects tackled in the DRI's Fast Track Center. In recognition of their generosity, the Dr. Denise R. and Thomas D. Stern Fast Track Center for Testing was named in their honor. “Our goal is to find a cure for Samantha and the millions of other children and adults living with this terrible disease,” explained Tom, managing director and a principal of Chieftain Capital Management in New York City. “Denise and I have put our trust in Dr. Ricordi and his amazing team of scientists. We are impressed not only by the caliber of scientists at the DRI, but also by the scope and the depth of cure-based research projects underway.” Over the years, the Sterns have kept abreast of new research advances and their confidence in the DRI has grown. They have recently committed an additional $2.5 million to help to further the testing of promising new ideas. “We decided to support the Fast Track Center in a more meaningful way to provide the resources needed for those projects that have the greatest promise and for which there is no grant money currently The words “estate planning” evoke a variety of emotions - from concerns for the well being of loved ones, and fears of facing one's own mortality, to desires to leave a mark or legacy, and the need to maintain a standard of living throughout one's life. In dealing with these important issues, professionals in the various fields associated with estate planning play a critical role. Below, three professionals share their insights and ideas on the topic. Tom and Denise Stern David Berg has been practicing law for 43 years. Working side by side with his two sons and three daughters, his Miami, Florida, firm is truly a family affair. Their practice specializes in estate planning, elder law, wills probate, and trusts, etc. Berg's daughter, Erin, developed diabetes as a teen, creating the impetus for his family to become involved with the Diabetes Research Institute and Foundation. When Berg meets with clients, he always discusses the incorporation of charitable gifts into their plans. available. We are confident that Dr. Ricordi is channeling these funds and the Institute’s scientific abilities into what will one day be a cure.” For the Stern family, support of the DRI means more than just contributing money. Tom serves as vice chairman of the Foundation's national board of directors and chairman of its northeast board. “This is really important to me. Not only giving dollars, but also devoting considerable time and energy,” says Tom. “I am optimistic that a cure will come early in Samantha's lifetime and that the Diabetes Research Institute will have played a meaningful role in turning hope into reality.” “It is a legitimate avenue to reduce inheritance taxes which can deplete the estate of 30 - 50 percent of its assets,” explained Berg. “Besides, most of my clients have experienced something in their lives that has led to an affinity for some charitable cause. For those who are looking for a worthy organization to support, I am not shy about suggesting the DRI Foundation.” 1. With a smile, Berg added, “People often put off confronting estate planning issues, so I keep jars of chocolate kisses in my office to sweeten up meetings with clients.” Longtime Family Ties Lead to Million-Dollar Gift Master Degree in Accounting and Finance from the University of Miami in 1976, he joined the former accounting giant Touche Ross. In 1979, he went to Burger King Corporation, and served in various financial capacities in Miami and in Denver, CO. His tenure there included a stint as chief financial officer with its subsidiary Godfather's Pizza in Omaha, NE. Almost 10 years later, in 1988, he headed to San Diego to work for TransWestern Publishing's U.S. West division, a telephone directory publishing company serving Southern California. Shortly thereafter, the company put the division up for sale. Spotting a tremendous opportunity in the growing market, Rick and several other investors purchased the business through a leveraged buyout. After serving as CEO for more than a decade, he sold the company to Yellow Book USA in July of 2005. The CPA-turned-entrepreneur soon found himself in a position to fulfill the philanthropic dream that he held for so many years, and to help the organization that has been such an important part of his mother's life. After recently returning to Miami to retire near his family, Rick took a tour of the DRI for the very first time. “It was the most educational experience for me. In my business, you rarely get to go into a research facility to see what people are doing. It was so interesting, but at that point, I had already decided to make a donation,” he said. Longing to make his mother happy and to help further research progress, Rick announced his most generous gift of $1 million to the DRI. “My mom was so excited. She didn't even know until after the plaque was on the wall,” he said. “I never thought I'd be in a position to make a gift of this size. But I owe it all to my parents. They made sure all of the children got a good education and a good start in life. I'm happy to be able to give back.” Rick Puente cannot recall a time when his mother worked anywhere but at the Diabetes Research Institute. That's because Martha Puente first accepted a position as a pharmaceutical studies coordinator back in 1972, and today, at 76 years old, still reports to work each day as a senior accountant and is as committed as ever to the place she calls home. “My whole life has been here,” said Martha. “The people, the patients. I love the DRI and everybody I have been working with.” Her continued loyalty, coupled with more than three decades of stories about the Institute, left a lasting impression on Rick, 52, who was just a teenager when Martha started working there. “I remember listening to my mom talk about Dr. Skyler, about the work that he does, and how she saw little kids giving themselves insulin shots,” said Rick. “It really got my interest, and I felt that if I ever could give money, I would really love to do so.” The desire to support the DRI remained with Rick throughout his entire career, which took him from Miami to San Diego, with several stops in between. After earning a Attorney Peter Bort became acquainted with the DRI and Foundation while collecting research for one of his clients who was passionate about becoming part of the cure. Since many members of her family have been afflicted by the disease, this client was seeking a place that is at the forefront of diabetes research. After considering a number of options, she decided to name the Diabetes Research Institute Foundation as the beneficiary of her trust. Bort practices law in Norristown, Pennsylvania. For the past 20 years, his firm has devoted a large part of its efforts to the area of estate planning and administration. He recommends that his clients involve all of their financial advisors in the development of their plan and likes to communicate with the other professionals, including financial planners and accountants. He takes a holistic approach to planning, taking into consideration the client's asset picture, income requirements, and stage of life, as well as people and causes that are important to them. 2. Lawrence Bass is both an attorney and CPA practicing as an accountant for more than 30 years in Manhattan. He focuses his efforts on providing clients with estate, financial and elder care planning services. While serving on the board of a private foundation that has supported the DRIF, Bass learned about the life-saving research being funded. It is his strong belief that every individual can do something to make an impact on a charitable organization during or after his or her lifetime. “Planning is a process that doesn't happen overnight. It takes time to develop a philosophy of giving,” he said. In developing plans, Bass creates projections for his clients on the various scenarios from a tax point of view. However, that is only part of the equation, and then the philosophical point of view comes into play. “By examining your circumstances and interests, you will be guided as to what you want to do,” he continued, and advised that the whole family should become involved in the planning process on some level. 3. 1) David T. Berg, JD of Berg, Ettelman & Berg, P.A., Miami, FL 2) Peter Bort, JD of Law Offices of Peter E. Bort, Norristown, PA 3) Lawrence Bass, JD, CPA of Konigsberg Wolf & Co., P.C., New York, NY Rick Puente, with his mother, Martha Puente, in front of the donor recognition wall at the DRI. 4 “If one wants to be deliberate and purposeful in their manner of transferring assets from one generation to another, an estate plan is a necessity,” said Bort. “For someone who is just getting started on making their estate plans, the AARP and the Internet can serve as a tremendous resource.” He also explained that more companies are providing their employees with an Employee Assistance Program (EAP) as part of their benefits package. Legal services are often included among the benefits of many EAP's. Bort suggests that those who have these benefits take advantage of them and meet with an attorney to develop a plan. All of these professionals agree that the time and careful consideration that go into developing an estate plan is well worth the effort. A comprehensive plan enables individuals to care for themselves, their loved ones and the causes that are meaningful to them - now and in the future. 5 DRI Under the Microscope Around the DRI with Jay Skyler, M.D. Global Research Alliance Created to Cure Diabetes (continued from page 1) “We cannot work efficiently if we do not break the barriers of traditional academic research. The DRI Federation will be a 'Manhattan Project'-type effort, bringing together the top researchers in key scientific disciplines who can apply their respective expertise to curing this disease” said Camillo Ricordi, M.D., scientific director of the Diabetes Research Institute. “By expanding our collaborative interactions, we will achieve our goal in less time and make the best use of collective resources by supporting the institute or investigator that is most effective in one or more of the areas of research we've all agreed is required for islet transplantation to be truly successful and more widely available to patients.” Today, islet transplantation is considered the most promising method for treating diabetes. Clinical studies have shown that infusions of insulin producing islet cells can eliminate the need for insulin injections in patients with type 1 diabetes. However, long-term results indicate that after three years of receiving an islet transplant, less than half of the patients remain insulin independent. Additional challenges posed by anti-rejection medications and their associated side effects, for one, continue to hamper the therapy's widespread application as a standard treatment. “Further improvements are necessary to make islet transplantation a routine clinical procedure for those with diabetes. We must overcome the limitations, which include an inadequate supply of donor pancreata, varying experience of islet isolation teams at centers performing the procedure, adverse side effects of immunosuppressants, and inconsistent long term results,” said Dr. Shinichi Matsumoto of Kyoto University Hospital in Kyoto, Japan, a member of the DRI Federation. These improvements can only result from an integrated research effort. Dr. Camillo Ricordi and his team first published the strategic model for this integrated research approach, or “roadmap to the cure,” in the journal Transplantation in 2004. Comprised of 11 key areas of research, the strategic model forms the basis for the DRI Federation's collaborative partnership (see diagram). Working in the areas of “Donor Strategies” and “Pancreas Procurement,” for example, Dr. Matsumoto and his team have been working at optimizing procedures for isolating islet cells from marginal donor pancreases to help alleviate the shortage of insulin-producing cells. The “Kyoto Islet Isolation Method” utilizes the organs from non-heart-beating donors that were previously rejected for transplant use due to their poor quality. The Kyoto researchers are also exploring other techniques to increase islet supply and obtain high islet yields. On the other end of the spectrum, Federation partners are investigating ways to eliminate the problem of scarce donor availability altogether. Together with Israel's D-Cure, DRI scientists are attempting to convert a portion of the patient's own liver cells into insulin producing tissue. Like these investigators, the other Federation teams are tackling many research areas that 6 are critical for stem cell research, regeneration of islets, and approaches to achieve donor specific tolerance, among other emerging technologies. “We are enormously optimistic that the pan-global efforts of the DRI Federation will pay off with the ultimate cure, and we are enormously proud to be a small part of that effort,” said James Shapiro, M.D., Ph.D., director of the Clinical Islet Transplant Program at the University of Alberta in Edmonton, a longtime collaborator of the DRI whose team is working in a number of the research strategy areas. “We must transfer any new pertinent finding toward new treatments for patients in the fastest, most efficient and safest way possible," said Dr. Ricordi. “We invite more research centers to join our efforts and add their respective expertise to the cause.” To learn more about the DRI Federation, visit www.diabetesresearch.org. In addition to major advancements in cure-focused research, monumental changes have been made in diabetes management over the past three decades. In the 1970s, there were no tools for accurately self-monitoring blood glucose levels, or any way for patients to safely and scientifically calculate changes in insulin dosages to compensate for their varied lifestyles. Patients were seen by their doctor on an average of only three times per year, and they received no supplemental care from any other healthcare provider, like a diabetes educator or dietician. What they soon did have, however, was a new patient care champion, Dr. Jay Skyler, who was committed to furthering new clinical research breakthroughs and providing patients with the most cuttingedge techniques to better control their disease. His development of the “Skyler Algorithms” quickly became the accepted guide for self-dosing of insulin. With his continued encouragement, patients closely monitored their blood sugar levels and took charge of their own health, which ultimately led to better glycemic control. In addition to pioneering new management practices, Dr. Skyler also helped create the journal Diabetes Care, and was its first editor-in-chief, promoting the need for patients to be served by an entire diabetes healthcare team. Throughout his 35-year career, Dr. Skyler has continued to make significant contributions to clinical diabetes research and patient care, and is highly regarded as one of the most distinguished investigators in the field. He currently serves as professor of medicine, pediatrics, & psychology in the Division of Endocrinology, Diabetes & Metabolism at the University of Miami, and as associate director for academic programs at the Diabetes Research Institute. He is also program director of the University of Miami General Clinical Research Center (GCRC). Among his many noteworthy roles, Dr. Skyler is study chairman for the National Institutes of Health (NIH)-sponsored TrialNet, in addition to holding other positions within numerous lay and medical organizations. Q. What new management options are available for patients that will help improve their quality of life? A. We are on the threshold of having continuous glucose monitoring (CGM) systems reach the clinical arena. These will allow people to have a better handle on their blood sugars and should help people achieve better control. Q. What current research studies will have the greatest impact on people with diabetes? A. TrialNet, which is a large consortium of clinical centers and physicians that are dedicated to the prevention and intervention of type 1 diabetes. TrialNet conducts studies to identify people at risk for developing diabetes, to find ways to circumvent the development of the disease, and to slow disease progression in newly-diagnosed people. It is comprised of 13 US centers, and international partners in Canada, Italy, Germany, Finland and Australia. The approved studies are based on sound, scientific rationale and are conducted in accordance with strict trial guidelines to prevent bias. Current studies focus on the immune and metabolic profiles of people at risk for developing type 1 diabetes. 7 Also underway is a prevention trial to test two immunosuppressive drugs that may preserve beta cell function in people with new-onset diabetes. Three additional studies are scheduled to begin in early 2006: • A continuing investigation of the oral insulin examined in the DPT-l national trial. • The testing of an immunosuppressive drug for its ability to stop the autoimmune attack on the beta cells. • A nutritional intervention protocol that will examine the effects of omega-3 fatty acids on preventing the autoimmune attack before it starts. The results of these large-scale trials will offer unprecedented information and improve our knowledge of this disease. Q. While these studies are encouraging for the intervention and prevention of diabetes, what hope can be offered to those currently living with diabetes? A. For people with type 1 diabetes who are not achieving adequate control, it's now possible to use pramlintide (Symlin), an analog of the hormone amylin that is produced in the same cells as insulin and is also deficient whenever insulin is. Pramlintide facilitates getting better control of blood glucose without weight gain - in fact often there is weight loss. Q. What aspect of your work gives you the greatest satisfaction? A. What I enjoy the most is trying to help people answer the questions that affect their lives. There is a challenge in conducting scientific studies and then analyzing the results to try to determine which are truly beneficial and which might be scientifically flawed. Just because a study was done, it doesn't mean that it was done correctly, with the right controls, and with the right group of participants. It is important to help my patients put to rest certain myths that seem to circulate throughout the community, but to still give them hope by reinforcing methods that are proven and correct. Researchers Find Striking Differences Between Human and Animal Insulin-Producing Islet Cells Sweet Rewards and a Birthday Benefit Kids Lend Their Support Discovery Alters 30 Years of Islet Cell Research, Changes Model Going Forward Diabetes Research Institute scientists have discovered that the internal structure of human insulin-producing islet cells is dramatically different than the well studied islets in rodents - a striking finding that will impact the way research is conducted if it is to benefit people living with diabetes. For more than three decades, scientists have based their knowledge of the cytoarchitecture, or cell structure, of islets on the rodent model. The structure of human islets has been poorly understood, but researchers assumed the cells had a similar make up. Now, Drs. Per-Olof Berggren and Alejandro Caicedo and their team have shown that the composition of a human islet is so different than that of the rodent model, it is no longer relevant for human studies. Their results were recently published in the Proceedings of the National Academy of Science. "Our major finding is that human pancreatic islets have a unique architecture, and work differently than rodent islets," said Dr. Berggren, adjunct professor at the DRI and professor at the Rolf Luft Center for Diabetes Research at Karolinska Institutet in Stockholm, Sweden. "We can no longer rely on studies in mice and rats. It is now imperative that we focus on human islets. At the end of the day, it is the only way to understand how they function." The islets of Langerhans, located in the pan- creas, regulate blood glucose levels. Islets consist of four types of secretory cells: insulin containing beta cells, glucagon containing alpha cells, somatostatin containing delta cells, and PP cells, which contain pancreatic polypeptide. The investigators compared the cellular composition of human islets to those of other mammalian species. In rodents, a layer of alpha, delta and PP cells cluster around a core of beta cells to form the islet structure. In humans however, all four cell types within the islet are mixed together, resulting in the beta cells having direct contact with the other cells. The research team also discovered that the beta cells were the most abundant cell type in the islets of all species. However, the proportion of beta cells was higher in the mouse islets than in the human cells, 77 percent vs. 55 percent. Additionally, 71 percent of mouse beta cells "associated" with their neighboring beta cells, while only 29 percent of human beta cells did so. Scientists think this construct affects the way all of the cells "talk" to each other, which could have a major impact on how islets respond to glucose and their ability to survive. The cells' survival is a key factor for successful islet transplantation, considered the most promising method for curing diabetes. During the procedure, the islets are first separated from a donor pancreas and then infused into the patient, where they begin to produce insulin. Researchers have shown that only the healthiest islets will be able to produce enough insulin to regulate blood sugars, as well as survive long term. For this reason, they have focused on developing tests that can predict the health and viability of an islet before it is transplanted into a patient. "This study was the first step in understanding the structure of the human islet. Now we need to better understand how human islets respond to glucose and how they secrete insulin," said Dr. Caicedo, research assistant professor at the DRI. "As we further our knowledge of human islet biology, we will be able to improve our methods to assess islet quality to determine whether to transplant them or not. This will be very important if we are going to establish islet transplantation as a standard therapy for patients with type 1 diabetes." While the study shows that the next step in the research process must be focused on human cells, scientists maintain that the use of rodent models continue to be relevant in “bench to bedside” or translational research. "The results of this study do not decrease the value of basic science and small animal based research," explained Dr. Camillo Ricordi, DRI scientific director. “However, it does underscore the critical importance of translational research, that is, to determine if observations obtained in rodent studies are relevant to patients. Using human tissues and pre-clinical model systems, we can transfer any new pertinent finding toward new treatments for patients in the fastest, most efficient and safest way possible." Ricordi Recognized for Outstanding Achievements Dr. Camillo Ricordi, the 2006 Lois Pope LIFE International Award recipient, with John G. Clarkson, M.D., departing dean of the University of Miami Miller School of Medicine, and benefactor Lois Pope. DRI Scientific Director Dr. Camillo Ricordi is regarded as one of the most accomplished scientists in the field of diabetes research, having been recognized for his significant contributions over the years by many national and international organizations. Recently, Dr. Ricordi received two more distinctions, again honoring his numerous research achievements. On March 7, during a special ceremony at the University of Miami Leonard M. Miller School of Medicine, he received the 2006 Lois Pope LIFE International Research Award. Dr. Ricordi is renowned for developing the method to separate and isolate insulin-producing islet cells from a donor pancreas. Started in 1999, the Lois Pope LIFE International Research Award honors outstanding scientists whose work has resulted in significant breakthroughs. The $100,000 award will go to the Miller School of Medicine to support the continued research efforts of Dr. Ricordi. He was also named a 2006 Health Care Hero® by the Healthcare and Bioscience Committee of the Greater Miami Chamber of Commerce. Dr. Ricordi, the winner of the Biomedical category, together with the winners of the other six award categories, was recognized during a ceremony at the Radisson Hotel Miami on March 9, 2006. The Health Care Heroes Awards honors the individuals, institutions and programs whose actions have made an extraordinary impact in the South Florida health care community. 8 Jordan, Emilio and Andrew asked for donations instead of birthday presents. A noticeable trend in gift activity has developed at the Diabetes Research Institute Foundation. A growing number of charitable donations are coming from the younger set - a much younger set! From grade school to high school, students are taking the search for a cure for diabetes into their own hands. Below, the DRIF would like to recognize some of our most recent youthful supporters and thank all of the kids who work hard to support our mission. Best friends bake for the cure, lend advice to others… During one of their regularly scheduled play dates last December, 8-year-olds Sam (Samantha) and Caroline were wondering how in the world they should spend their afternoon. With a nearly limitless list of options, the girls could have chosen a number of fun things to pass the time and stimulate their energetic bodies and minds. However, on this particular afternoon, they decided upon something a bit more enterprising and much more meaningful, resulting in a generous donation to the DRI. “We didn't know what else to do so Caroline suggested a bake sale, and we decided to make it for diabetes,” said Sam. “We chose the DRI so that they can find a cure for people.” Included in that group of people is Sam herself. Diagnosed with type 1 when she was just 22 months old, Sam cannot recall a time when she didn't have the disease, but is hopeful that the future will be different. Her parents, Tom and Denise Stern, are passionate supporters of the DRI, and Tom serves as vice chairman of the Foundation's national board and chairman of the northeast regional board. The penchant for philanthropy runs deep in the Stern household. Sam is already off to a great start, and little brother Tyler is certain to follow her example. On that day, the girls baked the cookies themselves, with a little help from an adult, and decided upon star-shaped sugar cookies Sam and Caroline made signs to help promote their cookie sale. and chocolate fudge cookies, which Sam pointed out was the hot seller. Then, they set up for the sale on a bench in the lobby of Sam's apartment building. Finally, they strategically planned the time of the sale in the late afternoon when most residents were coming home from work. These adept third graders knew that resisting a cookie would be nearly impossible after a long day at the office. “We made signs and started going up to people asking them to buy cookies for the DRI,” explained Caroline, who played the salesperson, even stopping people who were obviously in a hurry. “People were very happy to support such a worthy cause!” “We will definitely do it again, but something a little bigger next time. We started with cookies, but now we're really going to bring it out,” declared Caroline, who also has a strong interest in helping to find a cure for her cousin and grandpa. After their first foray into fundraising, the girls wanted to pass along some helpful advice for other kids who might want to hold a bake sale for the DRI. “Make sure your set-up area has a lot of people. Don't forget to make signs and make sure you have enough time. You'll need adult supervision for the baking and just run up to all the people who pass by,” they alternated, finishing each other’s sentences as best friends do. Friends give up birthday gifts for DRI donations… In January, good friends Emilio, Andrew and Jordan did something that most kids would never dream of doing. They gave up their birthday presents! Since they were all turning 11 around the 9 same time, they decided to hold a joint birthday party and invited more than 50 friends. With each invitational phone call, the boys asked for a contribution to one of two charities in lieu of gifts. Guests asked incredulously why these kids would elect not to receive any presents, but Emilio replied, “We just had Hanukah and Christmas. We don't need anything, and I feel like I am doing something really good.” Emilio selected the DRI as one of the beneficiaries for their event. He was well aware of the organization since his parents, Cathleen and Emilio Lamar, have served as committee members for several fundraising events. An immediate cure for diabetes has been a priority for him ever since his younger brother, Felipe, was diagnosed with type 1. “If I can help find a cure for Felipe so he doesn't have to take four shots a day anymore, it's better than any birthday present.” Andrew hosted the soiree at his house. At the entrance, the boys placed a simple box with the words, “Thank you for your donation,” printed on top. A 12-year-old deejay had the place rocking. The boys played basketball while the girls practiced their dance moves. Then, they all joined together for line dancing and games. After gobbling down pizza and ice cream cake, they called it a night. Once it was over, the boys were as eager to count the donations as they would have been to open their own gifts. After multiple recounts, they announced to their families that they had collected upwards of $2,000, which was split between the two charities. “When God blesses you with a wonderful family and everything you could ask for, the least I can do is give up my birthday gifts,” Jordan said poignantly. Andrew added, “I know what hard lives so many people have, and I realize how fortunate I am.” That night, the three friends went to bed with an enormous sense of pride and a maturity well beyond their 11 years. Thanks to the support of these charitable children, and so many others, the DRI is one step closer to finding a cure. If you are a student or if you have a child who would like to get involved, please call 1-800-3213437 and ask about the Diabetes Diplomats program, or visit www.diabetesresearch.org. Celebrating 32 Years of Love and Hope 1. 2. 3. 4. 5. An Unforgettable Performance The mood was electric; the dance floor was alive; and the guests were rapt with anticipation of the 32nd annual Love and Hope Ball's featured entertainment - a private concert by Barry Gibb. As the lights dimmed and the band struck that first chord of the classic Bee Gees hit, Jive Talking, approximately 800 people simultaneously sprung to their feet with an explosion of applause as Barry and Robin Gibb - reunited on stage for the first time in more than three years. Every single body in the room was in motion as the brothers performed Bee Gees hits spanning the last 35 years, including crowd favorites like Staying Alive, Lonely Days Lonely Nights, and 6. Massachusetts. The exhilarating momentum continued to build, culminating with a heart-pounding encore, You Should be Dancing. The set also included a poignant tribute to Maurice with the song, 1) Executive Chairman Sandra Levy, Humanitarian Don't Forget to Remember. It was the first time the two brothers had performed together since he Honoree Eleanor Lowe, Life Chairman Sonja passed away. Their last performance as a threesome was at the Love and Hope Ball in 2002. Zuckerman, and International Chairman Linda Gibb 2) Honorary Chairmen David Nepo and Jamie Jo Just before the concert, local meteorologist Bob Soper led the dinner program and recognized the Harris Nepo 3) Love Honorees Steven Posner and evening's VIPs: Honorary Chairmen Jamie Jo Harris Nepo and David Nepo, Humanitarian Honoree Kathryn Chesler 4) Silver Star Florence Frank and Eleanor Lowe, Love Honorees Steven Posner and Kathryn Chesler, Hope Honoree Shirley Harris, Cocktail Hope Honoree Shirley Harris 5) Cocktail Reception Reception Hosts Sandy and Senator Paul Steinberg, Silver Star Florence Frank, and Preview Party Hosts Senator Paul and Sandy Steinberg 6) Barry Gibb, Underwriter Isabel May. Life Chairman Sonja Zuckerman also took the stage and thanked International joined on stage by his brother, Robin, performed Bee Chairmen Linda and Barry Gibb, Executive Chairman Sandra Levy, National Chairman Kathy Simkins, Gees hits spanning the last 35 years and the entire Love and Hope committee for their hard work and dedication. Held at the Westin Diplomat Resort & Spa on February 18, this spectacular affair also featured a silent auction of exclusive items, including Lady Samba, a brilliant sapphire and diamond watch, courtesy of Meyers USA and Saks Fifth Avenue, Bal Harbour, and a fabulous diamond and pearl necklace, valued at $12,500, courtesy of Buchwald Jewelers. Guests had the chance to speak with jewelry craftsman, Alexandros, who displayed his elegant and timeless collection and also donated an extraordinary handcrafted necklace for the auction. Special thanks were offered to Saks Fifth Avenue, Bal Harbour for once again providing the favors, National Distributing Company, which donated the dinner wines and champagne, and sponsor Mellon Bank. The Heart of Love and Hope Behind the grandeur of the Ball is what is always referred to as the “heart of Love and Hope” - the elegant Preview Party, which was held on December 8 at the Diplomat Country Club in Hallandale. It is at this event that the commitment of the Love and Hope committee and all of its supporters truly shines. For the fourth consecutive year, the very generous Isabel May underwrote the evening, which began with a cocktail reception that featured a dazzling display of jewelry, courtesy of Neiman Marcus. Life Chairman Sonja Zuckerman and Executive Chairman Sandra Levy led the dinner program, which included a presentation by the DRI's Dr. Norma S. Kenyon. Not only is Dr. Kenyon a renowned scientist, but she's also a mother of a child with diabetes. Her 13-year-old daughter, Laura, who was diagnosed as a baby, also took the stage to thank everyone in attendance. Many guests responded with significant contributions, and the evening concluded with a few fabulous numbers by the La Mystique dance troupe and hip-swinging music by the Sol Varon Orchestra. Combined proceeds from the Love and Hope Ball and the Preview Party totaled more than $1 million. On the heels of another successful season, the Love and Hope committee has already set the date for the 33rd annual Love and Hope Ball - February 17, 2007, at the Westin Diplomat Resort & Spa. For more information, call the Diabetes Research Institute Foundation at 1-800-321-3437 or visit www.diabetesresearch.org. Sonja Zuckerman with Preview Party Underwriter Isabel May, and Lisa Perri-Molina of Neiman Marcus, sponsor 10 Putting the Fun in Fundraising Customarily, fundraisers cater to adults with elegant dinners, informative speakers, formal galas and golf tournaments. Looking beyond tradition, three friends and mothers recently organized an event that appealed to the whole family. Empowered with their combined hope of a cure for their kids, Event Chairpersons Amy Weissman Katz, Carolyn Goldfarb and Vanessa Brous appropriately dubbed their event "Carnival for a Cure." A glance inside New York City's Puck Building on the afternoon of March 5 would explain why. More than 800 guests of all ages frolicked among clowns, balloon sculptors, tattoo artists, face painters, a storyteller, and a deejay. Snacking on hotdogs, popcorn, pretzels and snow cones and toting treasured prizes, they raced between an inflatable bounce house, a gladiator jousting station, a remote-control racetrack and an endless variety of other food and game booths. “Everyone was having a good time,” said Carolyn. She and her husband, Marc, attended the event with their twin 4-year-old daughters, Brooke and Isabelle. Brooke was diagnosed with type 1 diabetes shortly after her first birthday. “Because diabetes is a disease that affects the whole family, this event was an ideal way for us to help the DRI find a cure.” It was a family affair for Amy, as well, whose 7-year-old daughter, Remi, was diagnosed with type 1 diabetes at 21 months. Big sister Lindsay, 13, pitched in by inviting friends and classmates to the event, organizing 25 student volunteers, stuffing envelopes and goody bags, selling raffle tickets at the event, and writing thank you notes afterward. To top it off, she even donated $1,000 of her own money. “We put so much time and effort into this event because we truly believe in the DRI,” said Amy. “I have met with the scientists and I believe that one day the DRI will be the one that will find the cure for my daughter and for all the children living with diabetes.” Vanessa agrees that the DRI is the best hope for the cure. When her son, Jack, was diagnosed with type 1 diabetes two and a half years ago at age 4, she received a phone call from someone at the Diabetes Research Institute Foundation that transformed her into a lifelong advocate of the DRI. “I was so scared and overwhelmed, but after that conversation everything seemed okay,” Vanessa said. Filled with gratitude and hope from the DRI, the co-chairs “lived and breathed” Carnival for a Cure for more than a year. With proceeds exceeding $400,000, they are proud of their accomplishment, but this modest team attributes much of their success to the support and contributions of family, friends, committee members and sponsors. Abbott Diabetes Care generously underwrote the event debut while Russ Berrie & Company, Inc. donated more than 800 items for the prize booth. Raffle winners took home NBA memorabilia, memberships to NY Sports Club and Equinox, passes to Regal/UA Theaters and Great Adventure, golf foursomes, handbags, clothing and stays at Trump Grande and Ritz-Carlton San Juan hotels. Additional food was donated by Dean & Deluca, Blockheads & Benny's Burritos, Samian Sales, Fresh Direct, Coca-Cola Company, Atlantic Supermarket, CHEEZWHSE, Bear Naked All-Natural Breakfast Foods, Slim Slammers, and many others. 2. 3. 1. 1) Northeast board member Ricardo Salmon and his wife, Leslie, who are also co-chairing the upcoming New York Research Update, enjoyed the event with their son, Mathias, and daughter, Eliana. 2) Event Chairpersons Amy Weissman Katz, Vanessa Brous, and Carolyn Goldfarb (far right) enjoy the festivities with Tom Stern, Northeast regional board chairman. 3) Face painting was a big hit, especially for these two wild men. D.R.E.a.M.S. Come True Certain to attract New York's trendiest professionals, the inaugural D.R.E.a.M.S. in the city promises to be the most talked about social event this season. Combining Diabetes Research, Elegance and Modern Sophistication (D.R.E.a.M.S.), the event will capture the true essence of hip New York culture and lifestyle in a chic setting, amongst like-minded individuals who support the DRI. Presented by Wine Spectator and pulver.com, this elegant cocktail party will premier at the stylish Westside Loft from 6:30 to 9:30 p.m. on Thursday, May 18 and feature the culinary creations of one of New York's top caterers, plus cool cocktails, music and a silent auction of exclusive items, including diamonds, jewelry, and luxurious vacation getaways. According to Event Chairpersons Samantha Shanken Baker and Risa Pulver, the event's theme will commemorate the international spirit of collaboration at the DRI. Don't miss the celebration! For ticket or sponsorship information, contact the Foundation's northeast regional office, 212.888.2217 or [email protected]. 11 EVENTS California Long Island LAUGHTER IS THE BEST MEDICINE HAVING A BALL With an attendance of more than 1,200 guests and profits surpassing $1 million, it was another record-breaking year for the Empire Ball. Sponsored by the New York Real Estate Division of the DRIF, the soiree was held at the Grand Hyatt Hotel in New York City. Guests, including former football great Boomer Esiason (pictured left with his wife, Cheryl) and DRIF national board Vice Chairman Charles Rizzo (right) enjoyed a fabulous cocktail reception and dinner, and then danced to the rocking sounds of the New York Real Estate All-Star Band. TV personality Father Tom Hartman, Ball Chairman Peter L. DiCapua, and Robert A. Pearlman addressed the crowd, and once again, actor and comedian Ray Romano appeared in the vide portion of the program. Robert Selsam, regional manager of Boston Properties, was recognized as the 2005 Empire Ball Honoree. And Joseph "Dee" Dussich, president and CEO of JAD Corporation of America, received the Camillo Ricordi Humanitarian Award. Performing before a sold-out, standing-room-only audience at The Improv in LA, primetime star Ray Romano (center) and fellow comedians Jon Manfrellotti and Jimmy Pardo brought the house down at Laugh for the Cure. (Pictured l-r) DRIF President Robert A. Pearlman, Event Co-chairs Paula Wilson and Hope Bolois, and DRIF National Board Chairman Marc S. Goodman enjoyed dinner, a live auction and a prize drawing along with the excited crowd before indulging in side-splitting laughter. The entertaining event raised more than $100,000. AN ENJOYABLE LABOR OF LOVE Sponsored by the Building and Construction Trades Department (BCTD) of the AFL-CIO, this year's Labor of Love golf tournament gave 125 of some of the most active supporters of diabetes research - including labor, business and government leaders - an opportunity to enjoy a friendly competition and maintain their commitment to the DRI. The event, held on February 25 at the Riverwalk Golf Club in San Diego, CA, raised $225,000. Pictured are DRIF President Robert A. Pearlman (far left) and BCTD President Ed Sullivan (center), accepting a check from Drew Varga of Harrah's Entertainment, Inc./Las Vegas Nevada representing Ballys, Paris, The Rio, Flamingo Las Vegas, Harrah's Las Vegas and Ceasar's Palace. Repeatedly the largest sponsor of Labor of Love, the hotel/casino conglomerate donates $1 per room per night occupied by BCTD members throughout the year. Northeast MEET US IN MANHATTAN DRIF national board member Lawrence Howard, M.D., and his wife, Judy (pictured), hosted the third Northeast Outreach Cocktail reception in their Manhattan apartment. Invited guests were treated to an informative presentation by the DRI's Dr. Juan DominguezBendala on the latest progress toward a cure. The series of receptions is meant to introduce new friends to the DRI. 12 WHERE FOOTBALL MEETS FASHION Jets' Chad Pennington, Jonathan Vilma and others modeling Brooks Brothers' finest clothing; members of the Jets Women's Organization decked out in Escada Couture; and a proverbial “Who's Who of Long Island” roaming the expanse of the Cradle of Aviation Museum for a good cause. It all happened at the eighth annual Fall Into Fashion, which raised more than $350,000. Chaired by Miriam Shiff and Addy Fritzhand the Fall Into Fashion event honored Jill and Brian Landow (pictured) for their work to raise awareness and funds in the search for a cure. The Landows also served as Runway Sponsors for the event. The highlight of the evening featured the latest styles from Escada and Brooks Brothers of the Americana Manhasset, modeled by the Jets players and members of the Jets Women's Organization. More than 500 guests enjoyed a strolling dinner, and silent and Chinese auctions. 13 EVENTS Florida A PASSIONATE FAMILY, A COMMITTEE OF SUPPORT On a mission to find a cure for their youngest son, Andrew, Andria and Javier Holtz (pictured with Robert A. Pearlman) once again chaired the DRI Golf and Tennis Classic, which was held at the La Gorce Country Club on January 30. Their dedication was matched by an incredible committee and a showering of support from local sponsors, elevating proceeds to more than $400,000. Following a day of sports, the evening featured an extensive silent auction, a cocktail reception and an awards dinner. During the program, Andria took the stage and with her heart on her sleeve stated, "Thank you, my friends, for making my passion your passion." PALM BEACH COUNTY AUXILIARY CONTINUES SUPPORT GENEROSITY PREVAILS AT DRI HAROLD KART GOLF CLASSIC Led by Event Chairpersons Renee Aronin (left) and Mariana Sherman (right,) nearly 200 women of the Palm Beach County Auxiliary gathered to support the DRI at Boca Greens Country Club on Monday, February 27, for the seventh annual A Gift of Love…A Gift of Hope Luncheon. Guests enjoyed a wonderful lunch followed by an afternoon of card games, such as canasta, Mahjong, pan and bridge. The women also delighted in another favorite pastime - shopping. Unique boutiques offered up fabulous items, including jewelry, clothing, handbags, and more. This year’s proceeds surpassed $21,000. If you live in Palm Beach County and are interested in joining this social group, please contact Mariana Sherman at (561) 883-0495. TAKING STRIDES TOWARD THE CURE A little rain wasn't enough to dampen the spirits of the 240 golfers at the DRI Harold Kart Golf Classic, which was held at the prestigious Boca West Country Club. According to Tournament Chairman Gary Studley, proceeds totaled more than $235,000. Following the tournament, guests enjoyed an extended cocktail reception and awards banquet, during which the grandchildren of event committee member Sandy Bodner gave heartwarming speeches. The youngest of three, Michael was diagnosed with type 1 diabetes seven years ago at age 5. According to the eldest sibling, Kati-Anne, just two years his senior, Michael's diabetes management has always been a family effort. Sixteen-year-old Lauren added that the family shares a strong, loving bond and hope for a cure. Bodner and his grandkids pictured with their parents Howard and Christina Bodner (right) and committee member Phyllis Tarlow (left). MILLION DOLLAR PLEASURES Dr. Camillo Ricordi, his wife, Valerie, and Chairpersons Sue and Doug Gallagher (Pictured l-r) welcomed more than 100 guests to Chef Norman Van Aken's Coral Gables restaurant, NORMAN'S, on October 17 for the eighth annual Pleasures of the Palate. Before the evening was through, guests contributed more than $140,000 to the cause, bringing the event's combined total to $1 million since inception. Latin Grammy nominee Roberto Perera provided musical entertainment as attendees sipped champagne, delved into delicious passed hors d'oeuvres and perused an extensive silent auction, featuring rare vintages of wine. They were then treated to a fabulous four-course dinner paired with the perfect complimentary wines, courtesy of National Distributing Company. 14 Five hundred members of Broward's National Honor Society (NHS) and Junior NHS, joined by teachers, friends, and relatives, walked, biked and skated through local parks Saturday, February 25, at the Seven-Mile Walk/Bike-A-Thon. Retired Cooper City High School teacher and NHS sponsor Audrey Dunn started the event more than 20 years ago, and Charles W. Flanigan High School senior Ashley Ehlinger (below, left) continues to organize it today. The event, which includes participants from more than 30 schools, marked the end of DRI Week, a unique campaign that allows participants to organize projects of their choice to create awareness and raise funds for the DRI. This year the Seven Mile Walk/Bike-A-Thon raised $12,000, and the top fundraiser, Jake Blumstein of Weston, brought in an astounding $3,000. Additional DRI Week projects continuing throughout the year will include a fashion show, a basketball tournament, dress-down days at school and work, street corner and storefront collections, a seafood festival and more. THE CIRCLE OF CHAMPIONS EXPANDS DRIF Florida board member and Olympic medalist Gary Hall, Jr. and his wife Elizabeth hosted a fun, casual brunch at South Beach's world famous Joe's Stone Crab restaurant. During the cocktail reception, 250 attendees sipped mimosas and perused the silent auction while The Jean Caze Trio played elegant music, and beautiful models, courtesy of modeling agent Michele Pommier, strutted through the crowd donning fashions by Emilio Pucci. Hall inducted eleven-year-old honoree Andrew Holtz into the Circle of Champions for excelling as an athlete with diabetes. The Olympus Award was then presented to Michele Pommier (pictured above with Hall) for going the extra mile to contribute to the community. 15