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This information is general and no substitute for the individualised injection-training each patient will receive at MFS. It is important to take notes at this appointment as some treatment plans may vary depending on clinical need. Injections training appointment Following the treatment planning appointment, patients receive training to self-inject the fertility drugs required for the next stage of treatment. As each patient’s treatment is tailormade to their individual requirements, the drug types and protocols will vary. Patients are reminded not to compare their prescriptions with those of other patients. It is strongly recommended that: the female partner who will be having the injections is accompanied to the injection-training appointment by her husband, partner or a friend who can drive that someone should remain with the patient for at least one hour after administering any self-injected medication for the first time The following are the injectable medications most commonly prescribed at MFS: *Key: SC: sub-cutaneous - injected into the thigh, buttock, or tummy IM: intra-muscular - injected into the buttock or upper thigh *SC/IM Syringe and needle information ‘Down-Regulation’ Drugs Suppress the hormones LH and FSH before the ovarian stimulation phase of treatment buserelin (video available, see over) SC 1ml syringe, brown needle to inject decapeptyl 3mg (single dose) IM usually given by a clinician Ovarian Stimulation Drugs Stimulate the ovaries to produce more egg-containing follicles than the one or two usually produced in a natural cycle Merional (video available, see over) SC Fostimon (video available, see over) SC Menopur SC Gonal-f SC Anti-Ovulation Drugs 2.5ml syringe, green needle for mixing and brown needle to inject pre-filled syringe ready for injection Controlled prevention of premature ovulation Cetrotide SC pre-filled water in syringe, ready to add powder. Needle included in pack Orgalutran SC pre-filled syringe ready for injection ‘Trigger’ Shot / hCG buserelin (video available for SC, see over) hCG Luteal Phase Support progesterone Controls the exact time of ovulation. Gonasi, Choragon and Pregnyl Examples include: SC/IM SC=1ml syringe, brown needle to inject IM=2.5ml syringe, blue needle to inject SC/IM SC=1ml syringe, brown needle to inject IM=2.5ml syringe, blue needle to inject Maintains the lining of the uterus to aid embryo implantation IM 2.5ml syringe, green needle for mixing and blue needle to inject © (2013) Midland Fertility Services / 3,1 self-injecting v01-06/2013 Guide to Self-Injecting Drug name page 1 of 2 Video guides to self-injecting Patients who are prescribed: buserelin Fostimon® (Urofollitropin) Merional® (Menotrophin BP) can access on-line, video guides to self-injecting via the website of Pharmasure, the key supplier of patients’ drugs to MFS, as follows: open one of the following internet browsers: o Internet Explorer o Google Chrome o Firefox o Safari the guides are viewed best on a tablet or PC ensure the latest version of Flash Player is installed. To install or update Flash Player, visit: http://get.adobe.com/flashplayer/?no_ab=1 visit: www.pharmasure.co.uk click on ‘Video Guides’ A patient may choose to source her own medications – an additional fee is levied for private prescriptions. Equipment syringes mixing needles and injecting needles sharps’ bin (for safe disposal of needles, syringes, vials and/or ampoules). Do not overfill the sharps’ bin so that the lid does not shut. It must be returned to MFS or to a GP surgery for safe disposal and MUST NOT be included in household waste ampoule breakers are supplied to patients only for MFS-supplied Fostimon and Merional How to store fertility drugs Drugs must be stored between 4-18°C. Refrigeration is not required. Refer to the leaflet supplied with the medication. Tips select the relevant self-injecting guide from the drop down menu patients should refer to the ‘Treatment Schedule’ in the MFS blue patient’s folder detailing the types, dates and quantities of the drugs they have been prescribed if preferred, the patient’s partner can do the injections (but only if they’ve received the training) expensive numbing creams aren’t necessary, but some patients find it easier to numb the spot with an ice-cube before the hCG injection do the injections at the same time every day, unless instructed otherwise Side-effects of self-injecting medication Fertility medications may cause some ‘normal’ side effects, including local irritation or redness. If any other side-effects are noticed the patient should contact MFS (see below). ensure the sound is turned on watch the whole video before preparing to selfinject and until the procedure is familiar Are medications included in the treatment cost? How fertility drugs are obtained and supplied Injectable fertility drugs are supplied as either: vials: have a rubber stopper ampoules: have a glass ‘nipple’ that needs to be broken off. Please take care when opening They are received with all the necessary equipment for safe self-injecting: private patients: all drugs – and some equipment for Fostimon and Merional – are delivered directly to the patients’ homes. Other equipment will collected by the patient at MFS NHS patients: collect their drugs and equipment from MFS at the injection training appointment for private patients, the cost of drugs is calculated on individual patient need. Patients will be advised of the cost at the appointment following treatment assessment. The cost for any required ‘top-up’ drugs will be discussed with the patient as required and must be paidfor before receipt drugs for NHS patients will be supplied as part of their treatment package Further information If in any doubt about injecting medications, patients should email [email protected] or contact the clinical team during usual clinic hours on 01922 455911. Out of hours, a voice mail message will state the mobile number of the senior on-call member of staff to contact. If in any doubt, ASK! © (2013) Midland Fertility Services / 3,1 self-injecting v01-06/2013 page 2 of 2