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HMF Probiotics
PROFESSIONAL PRODUCT GUIDE
NEW
New products inside
Clinically proven, proprietary,
human-sourced strains
Visit www.seroyal.com/genestrabrands to view the entire GENESTRA BRANDS line
Dedicated to making a difference in peoples’ lives
Genestra Brands is a leading-edge line of professional-grade nutraceuticals,
helping North American healthcare practitioners restore, rebuild and maintain patient health for over 30 years.
A trusted Seroyal brand.
490 Elgin Mills Road East, Richmond Hill, ON L4C 0L8
TEL: 1-800-263-5861 | FAX: 1-800-722-9953 | EMAIL: [email protected] | WEBSITE: www.seroyal.com
The aim of this comprehensive product guide is to assist in building more effective and successful patient treatment strategies. The product guide is to be used as an adjunct to Seroyal Continuing Medical Education and is not intended to be utilized as a diagnostic tool
nor replace any other required education. The remedies indicated in this product guide are potent medicines that can have profound therapeutic effects on patients. As with any intervention, the dosage may need to be adjusted for those with chronic conditions, very sensitive
individuals and those taking multiple medications. Practitioners are solely responsible for the care and treatment provided to their own patients. The information provided by the speaker or speakers in the Seroyal Continuing Medical Education program together
with any written material provided do not necessarily represent the views of Seroyal and are not intended as medical advice or an endorsement of any products. This information is for practitioner use only.
Copyright © 2015 Seroyal. All rights reserved. No part of this information may be used or reproduced in any form or by any means, or stored in a database or retrieval system, or be distributed or replicated without express permission of Seroyal. Making copies of any part of this information for any
purposes other than your own personal use is a violation of copyright law.
2190. Version 45.
ii
TABLE OF CONTENTS
Probiotics 101 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Market leader:
Driving probiotic science and innovation
for over 30 years. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
HMF Product Overview
MAINTENANCE
HMF Pre + Probiotic. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
HMF Capsules. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
HMF Forte. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
HMF Super Powder. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
HMF Powder. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
HMF Multi Strain. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
HMF Intensive. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
HMF Intensive Powder. . . . . . . . . . . . . . . . . . . . . . . . . . . 6
HMF Replenish Capsules. . . . . . . . . . . . . . . . . . . . . . . . . 6
HMF Replete. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
IBS SYMPTOMS
HMF IBS Relief. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
POST ANTIBIOTIC CARE
HMF Antibiotic Care. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
HMF Probiotic Product Comparison Chart. . . 8-9
Probiotics 101
What are probiotics?
There are billions of bacteria living in the intestinal
tract often referred to as ‘microflora’. Probiotics are live
“friendly” bacteria found in the microflora working to
keep a healthy intestinal balance, reducing the amount
of harmful bacteria while replenishing and maintaining
beneficial strains. Maintaining this balance is critical for
overall good health.
Why supplement
with probiotics?
Beneficial bacteria may be reduced due to a variety
of factors:
• Dietary changes or
•Age
poor diet
• Antibiotic or
other medication use •Stress
• Digestive disorders
• Infection or illness
• Traveling
•Lifestyle
Who should take
probiotics?
Daily probiotic supplementation is considered a
necessary component of any healthy diet. It supports
health in:
• Pre- and post-pregnancy
• Infants (1 year+), children and adolescents
•Adults
•Seniors
While probiotics may be added in foods such as yogurt
and smoothies, direct probiotic supplementation
provides the highest amount of beneficial live and active
cultures. Probiotics should be a routine part of a daily
lifestyle to help maintain optimal health conditions.
An unhealthy balance between the beneficial and
harmful bacteria may affect gastrointestinal function.
EXPORPHIN DEGRADING (in vitro)
HMF Neuro Capsules. . . . . . . . . . . . . . . . . . . . . . . . . . . 10
HMF Neuro Powder. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
URINARY SUPPORT
HMF Cystgen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
YEAST INFECTION SUPPORT
HMF Candigen Cream . . . . . . . . . . . . . . . . . . . . . . . . . . 11
HMF Candigen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
PREGNANCY AND CHILD SUPPORT
NEW
NEW
HMF Maternity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
HMF Maternity + Pro. . . . . . . . . . . . . . . . . . . . . . . . . . . 12
HMF Child. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
HMF Baby B . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
HMF Baby F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
HMF Natogen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
HMF Toddler + Pro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
Clinical Trials
The Swansea Baby Trial. . . . . . . . . . . . . . . . . . . . . . . 15-16
The ProChild Study. . . . . . . . . . . . . . . . . . . . . . . . . . . 17-18
The Sheffield IBS Trial . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
The Cambridge Probiotic / Antibiotic Trial. . . . . . . . . 20
The Swansea ‘Safety in Newborns’ Study. . . . . . . . . . 20
All ages can benefit from probiotic supplementation.
1
Market leader
Driving probiotic science and innovation for over 30 years
GENESTRA BRANDS Human MicroFlora (HMF) probiotics incorporate safe and effective strains reflecting the latest
evidence-based research from human trials, and provide physicians and healthcare professionals a comprehensive range
for individualized or condition-specific treatment.
Human-sourced strains
Natural pH and bile acid resistance: No enteric coatings required
Human-sourced microflora bacterial strains have high survival rates through various stomach pH (1.8- 4.2) thus maximizing
intestinal tract exposure and eliminating the need for enteric coatings (capsule/tablet barriers that control digestive absorption).
Naturally strong adherence: High ratio of intestinal tract carriage
CFU (Colony Forming Unit) levels are important but effectiveness is best determined through intestinal tract carriage. Human-sourced
microflora bacterial strains have a naturally strong adherence to epithelial cells thus ensuring high ratios of intestinal tract carriage.
Clinically proven:
Human trials demonstrate safety and efficacy
Clinically proven in randomized, double-blind, placebo-controlled human trials
25 billion CFU/day of:
• Lactobacillus acidophilus (CUL-60)
• Lactobacillus acidophilus (CUL-21)
• Bifidobacterium bifidum (CUL-20)
• Bifidobacterium animalis subsp. lactis (CUL-34)
Clinically proven to:
• Improve symptoms of irritable bowel syndrome (IBS) within 6 weeks
•Reduce bloating, increase satisfaction with bowel habits,
and decrease days with pain
• Restore normal micro flora composition following antibiotic therapy
Probiotic expertise: Global research and development drive category innovation
A collaborative think-tank lead by Dr. Plummer produced over 70 peer reviewed and PubMed listed publications.
10 billion CFU/day of:
• Bifidobacterium bifidum (CUL-20)
• Bifidobacterium animalis subsp. lactis (CUL-34)
• Lactobacillus silvarius (CUL-61)
• Lactobacillus paracasei (CUL-08)
Clinically proven:
• Safe for use during infancy
Nigel Plummer PhD: Global authority on probiotics
This key probiotic contributor has worked at Pfizer in antibiotic R&D. A continued commitment to research has resulted in
collaborations with research institutes and universities within the UK and Europe, developing an extensive knowledge specializing in
probiotics, natural antimicrobials and fish oils.
Comprehensive range: Convenient formats,
age-specific and condition-specific formulas
Available in an array of potencies (up to 150 billion CFU), formats
(capsules, tablets, powders) and flavours toallow for flexibility in
dosing and improved patient compliance. Therapies can be tailored for
specific individualized treatments by age (pregnancy support, infants,
and children to seniors) or condition-specific probiotics (exorphin
degrading, IBS, antibiotic, urinary and yeast infection support).
2
Get an Early Start
on Immune and
Digestive Health
NEW
GENESTRA BRANDS HMF Baby B (for breast fed
babies) and HMF Baby F (for formula fed babies)
each provide 10 billion CFU of clinically-proven
human-sourced strains, to promote an optimal
gut flora and support digestive health. Infant
microflora composition is an important factor in early
immune development, and sub-optimal microflora
composition may impact risk of developing atopic
disease. In a recent clinical trial, supplementation with
the probiotic formula used in HMF Baby B and
HMF Baby F reduced atopic eczema incidence by 57%
and decreased skin prick reaction to cow’s milk and
egg allergens by 44%.
HMF Baby B includes additional microflora support
from added galactooligosaccharides (GOS), a prebiotic
fibre similar to oligosaccharides naturally within
breast milk. HMF Baby F contains both GOS and
fructooligosaccharides (FOS).
3
MAINTENANCE
HMF Pre + Probiotic
HMF Capsules
HMF Forte
PROBIOTIC FORMULA
PROBIOTIC FORMULA
PROBIOTIC FORMULA
Low level maintenance probiotic + prebiotic fibre
• 1.25 billion CFU per dose
•Includes prebiotic fibre from fructooligosaccharides (FOS)
and soluble fibre from psyllium husk
•Helps stimulate the growth of intestinal Bifidobacteria
•Provides gentle relief of occasional constipation
HMF Pre + Probiotic is a low level, long-term maintenance
synbiotic formula which provides two strains of proprietary
human-sourced Lactobacillus acidophilus, Bifidobacterium
bifidum and Bifidobacterium animalis subsp. lactis, along with
fructooligosaccharides to specifically assist in maintaining a
normal intestinal microflora.
EACH SCOOP (5 g) CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 1.25 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Fructooligosaccharides (FOS) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.5g
Psyllium (Plantago ovata) Husk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.19 g
Recommended Dose: Adults and Adolescents (12 years and
older): In a glass, add eight ounces (250 ml) of water or juice to
two scoops of HMF Pre + Probiotic and mix. Take two times daily,
at least two to three hours before or after taking antibiotics or other
medications, or as recommended by your healthcare practitioner.
Drink a full glass of liquid with each serving. When used as a gentle
laxative, effects are observed twelve to twenty-four hours after first
dose, and may take two to three days.
250 g Powder
NPN 80041616
4
Product Code: 10423
Low level maintenance probiotic
•2.5 billion CFU per capsule
•Contributes to a natural healthy gut flora
HMF Capsules are a low level, long-term maintenance
probiotic formula which provides two strains of proprietary
human-sourced Lactobacillus acidophilus, Bifidobacterium
bifidum and Bifidobacterium animalis subsp. lactis, to
specifically assist in re-establishing and maintaining a normal
intestinal microflora.
EACH CAPSULE CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . 2.5 billionCFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Non-Medicinal Ingredients: Cellulose, hypromellose, silica,
magnesium stearate
Recommended Dose: Adults and Children (6 years and
older): Take two capsules two times daily with meals, at least
two to three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
60 Vegetable Capsules
NPN 80020672
Product Code: 10409
Moderate level maintenance probiotic
•10 billion CFU per dose
•Includes fructooligosaccharides (FOS)
Long-term maintenance
•Supporting a healthy normal digestive flora
Ideal for vegans
• Convenient vegetable capsule format
HMF Forte is a moderate level, long-term maintenance
probiotic formula which provides two strains of proprietary
human-sourced Lactobacillus acidophilus, Bifidobacterium
bifidum and Bifidobacterium animalis subsp. lactis, along with
fructooligosaccharides (FOS).
EACH CAPSULE CONTAINS: Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 10 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Non-Medicinal Ingredients: Cellulose, fructooligosaccharides
(FOS), hypromellose, silica, magnesium stearate
Recommended Dose: Adults and Children (6 years and
older): Take one capsule two times daily with meals, at least
two to three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
60 Vegetable Capsules
120 Vegetable Capsules
NPN 80020755
Product Code: 10418
Product Code: 10418120
MAINTENANCE
HMF Super Powder
HMF Powder
HMF Multi Strain
PROBIOTIC FORMULA
PROBIOTIC FORMULA
PROBIOTIC FORMULA
Moderate level probiotic
•10 billion CFU per dose
Ideal for vegans
•Convenient powder format
Moderate level maintenance probiotic
•11 billion CFU per dose
•Includes fructooligosaccharides
Ideal for vegans
• Convenient powder format
HMF Super Powder is a moderate level maintenance probiotic
formula which provides two strains of proprietary humansourced Lactobacillus acidophilus, Bifidobacterium bifidum and
Bifidobacterium animalis subsp. lactis, along with
fructooligosaccharides, formulated to assist in re-establishing
and maintaining normal intestinal microflora. HMF Super
Powder is indicated for the promotion and maintenance of
intestinal health in adults and children who dislike or have
difficulty swallowing capsules.
EACH SCOOP (1 g) CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . . 10 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Non-Medicinal Ingredient: Fructooligosaccharides (FOS),
fructose
Recommended Dose: Adults and Children (1 year and
older): In a glass, add water or milk to one scoop
(¼ teaspoon) of HMF Super Powder and mix. Take two times
daily with meals, at least two to three hours before or after
taking antibiotics, or as recommended by your healthcare
practitioner.
120 g Powder
NPN 80020678
Product Code: 10427
HMF Powder is a moderate level maintenance probiotic formula
which provides two strains of proprietary human-sourced
Lactobacillus acidophilus, Bifidobacterium bifidum and
Bifidobacterium animalis subsp. lactis, along with
fructooligosaccharides. HMF Powder is indicated for the
promotion and maintenance of intestinal health in adults and
children alike.
EACH SCOOP (1 g) CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 11 billion.CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Fructooligosaccharides (FOS) . . . . . . . . . . . . . . . . . . . . . . . . 880.mg
Recommended Dose: Adults and Children (1 year and
older): In a glass, add water or milk to one scoop
(¼ teaspoon) of HMF Powder and mix. Take two times
daily with meals, at least two to three hours before or after
taking antibiotics, or as recommended by your healthcare
practitioner.
60 g Powder
NPN 80041897
Product Code: 10408
Moderate-level maintenance probiotic
• 15 billion CFU per dose
• No FOS
16 probiotic strains
• Includes proprietary human-sourced strains
Supports a healthy normal digestive flora
•Provides live microorganisms that temporarily
modify gut flora
HMF Multi Strain is a moderate-level, long-term maintenance
probiotic formula which provides sixteen strains including
proprietary human-sourced Lactobacillus acidophilus,
Bifidobacterium bifidum and Bifidobacterium animalis subsp.
lactis. The capsules are 100% pure vegetable-sourced which
makes the product ideal for vegans.
EACH
CAPSULE CONTAINS: Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 15 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus salivarius (CUL-61)
Lactobacillus paracasei (CUL-08)
Lactobacillus plantarum (CUL-66)
Lactobacillus casei (CUL-06)
Lactobacillus fermentum (CUL-67)
Lactobacillus gasseri (CUL-09)
Bifidobacterium animalis subsp. lactis (CUL-62)
Bifidobacterium breve (CUL-74)
Streptococcus salivarius subsp. thermophilus (CUL-68)
Lactobacillus acidophilus (NCFM™)
Bifidobacterium animalis subsp. lactis (HN019)
Lactobacillus rhamnosus (HN001)
Non-Medicinal Ingredients: Hypromellose, cellulose, silica
Recommended Dose: Adults, Adolescents and Children
(6 years and older): Take one capsule daily, at least two
to three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
60 Vegetable Capsules
Product Code: 10487
NPN 80045939
5
MAINTENANCE
HMF Intensive
HMF Intensive Powder
HMF Replenish Capsules
PROBIOTIC FORMULA
PROBIOTIC FORMULA
PROBIOTIC FORMULA
High level probiotic
•25 billion CFU per dose
Ideal for vegans
•Convenient vegetable capsule format
HMF Intensive is a highly concentrated probiotic formula which
provides two strains of proprietary human-sourced Lactobacillus
acidophilus, Bifidobacterium bifidum and Bifidobacterium
animalis subsp. lactis in a single daily dose capsule to support
the restoration of friendly intestinal flora. HMF Intensive is highly
recommended after completion of the HMF Replete program.
EACH CAPSULE CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 25 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Non-Medicinal Ingredients: Cellulose, hypromellose
Recommended Dose: Adults and Children (6 years
and older): Take one capsule daily with a meal, at least
two to three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
30 Vegetable Capsules
NPN 80020663
Product Code: 10431
Highly concentrated probiotic formula
• 25 billion CFU per dose
•Provides live organisms that temporarily
modify gut flora
Easy-to-use powder formula for
long-term maintenance
• Includes proprietary human-sourced strains
HMF Intensive Powder is a highly concentrated probiotic
formula, which provides two strains of proprietary
human-sourced Lactobacillus acidophilus, Bifidobacterium
bifidum and Bifidobacterium animalis subsp. lactis in a
single daily-dose powder to support the restoration of
friendly intestinal flora. It is fructooligosaccharide-free and
HMF Intensive Powder is highly recommended after
completion of the HMF Replete program.
HMF Replenish Capsules is a highly concentrated probiotic
formula in capsules which provides two strains of proprietary
human-sourced Lactobacillus acidophilus, Lactobacillus
salivarius, Bifidobacterium bifidum and Bifidobacterium animalis
subsp. lactis along with low concentrations of
fructooligosaccharides.
EACH CAPSULE CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . 100 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus salivarius (CUL-61)
SCOOP (1 g) CONTAINS:
EACH
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 25 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Non-Medicinal Ingredients: Fructooligosaccharides (FOS),
hypromellose, silica, magnesium stearate
Non-Medicinal Ingredients: Maltodextrin
14 Vegetable Capsules
Recommended Dose: Adults, Adolescents and Children
(3 years and older): In a glass, add water or milk to one
scoop of HMF Intensive Powder and mix. Take once daily
with a meal, at least two to three hours before or after
taking antibiotics, or as recommended by your healthcare
practitioner.
NPN 80023493
30 g Powder
6
High level probiotic
• 100 billion CFU per dose
• Includes fructooligosaccharides
Ideal for vegans
• Convenient vegetable capsule format
Product Code: 10486
Recommended Dose: Adults and Children (6 years
and older): Take one capsule daily with a meal, at least
two to three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
Product Code: 10457
MAINTENANCE
IBS SYMPTOMS
POST ANTIBIOTIC CARE
HMF Replete
HMF IBS Relief
HMF Antibiotic Care
PROBIOTIC FORMULA
PROBIOTIC FORMULA
PROBIOTIC FORMULA
High level probiotic
•150 billion CFU per sachet
Ideal for vegans
•Convenient powder sachet format
HMF Replete is a highly concentrated probiotic formula in
sachets which provides two strains of proprietary humansourced Lactobacillus acidophilus, Lactobacillus salivarius,
Bifidobacterium bifidum and Bifidobacterium animalis subsp.
lactis along with fructooligosaccharides in high concentrations
to ensure rapid establishment and dominance of probiotic
cultures in the gastrointestinal tract.
EACH SACHET (20 g) CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . . 150 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus salivarius (CUL-61)
Non-Medicinal Ingredient: Fructooligosaccharides (FOS),
apricot powder
Recommended Adult Dose: In a glass, add water to
½ sachet of HMF Replete and mix. Take once daily with
a meal, at least two to three hours before or after taking
antibiotics, or as recommended by your healthcare
practitioner.
7 x 20 g Sachets of Powder (140 g) Product Code: 10419
NPN 80020781
Probiotic for IBS support
•Clinically proven to improve symptoms of irritable bowel
syndrome (IBS) within 6 weeks1
•Reduces bloating, increases satisfaction with
bowel habits, and decreases days with pain
• 25 billion CFU per dose
HMF IBS Relief is clinically proven to significantly reduce the
severity of symptoms of intestinal discomfort and days with
pain, while improving satisfaction with bowel habits and overall
quality of life.1 Human MicroFlora (HMF) probiotic strains are
proprietary human-sourced microflora bacterial strains that
have strong epithelial adherence and a naturally high tolerance
to stomach acid.
EACH CAPSULE CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 25 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Non-Medicinal Ingredients: Cellulose, hypromellose
Recommended Dose: Adults and Children (11 years
and older): Take one capsule daily with a meal, at least
two to three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
30 Vegetable Capsules
Product Code: 10437
NPN 80020663
Probiotic for post antibiotic care
• Clinically proven to help restore normal micro flora
composition following antibiotic therapy1
• 100 billion CFU per dose
• Includes fructooligosaccharides
HMF Antibiotic Care is clinically proven to supplement the
normal intestinal microbiota following antibiotic therapy.
The Cambridge Probiotic/Antibiotic Trial concluded that this
proprietary blend of Human MicroFlora (HMF) strains was
effective in modulating intestinal microflora response to the
effects of antibiotic therapy.1 HMF probiotic strains are
human-sourced microflora bacterial strains that have strong
epithelial adherence and a naturally high tolerance to
stomach acid.
EACH CAPSULE CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . 100 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus salivarius (CUL-61)
Non-Medicinal Ingredients: Fructooligosaccharides (FOS),
hypromellose, silica, magnesium stearate
Recommended Dose: Adults and Children (6 years
and older): Take one capsule daily with a meal, at least
two to three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
14 Vegetable Capsules
Product Code: 10471
NPN 80023493
1.Plummer et. al. (2008) Clinical trial: a multistrain probiotic preparation significantly reduces
symptoms of irritable bowel syndrome in a double-blind placebo-controlled study. Aliment
Pharmacol Ther. 29:97-103.
1.Madden JAJ et al. Effect of probiotics on preventing disruption of the intestinal microflora following
antibiotic therapy: A double-blind, placebo-controlled pilot study. Int Immunophar 2005: 5:
1091-1097.
7
Condition-specific support
Comprehensive range in convenient formats
For individualized treatment, HMF probiotics are available in an array of potencies and formulas to allow for flexibility and efficacy.
Human MicroFlora (HMF) Probiotics Comparison Chart
8
CFU PER
DOSAGE UNIT STRAINS
OTHER ACTIVE
INGREDIENTS
FOS RECOMMENDED DOSE
Probiotic and prebiotic to
promote a natural healthy
gut flora
1.25 billion
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
Psyllium husk
Yes
HMF Capsules
Low level maintenance
2.5 billion
No
HMF Forte
(capsules)
Moderate level
maintenance
10 billion
HMF
Super Powder
Moderate level
maintenance
10 billion
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. acidophilus (CUL-60)
L. acidophilus (CUL- 21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
HMF Powder
Moderate level
maintenance
11 billion
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
Yes
HMF Multi Strain
(capsules)
Moderate level
maintenance
15 billion
No
HMF Intensive
(capsules)
Intensive use
25 billion
HMF Intensive Powder Intensive use
25 billion
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. salivarius (CUL-61)
L. paracasei (CUL-08)
L. plantarum (CUL-66)
L. casei (CUL-06)
L. fermentum (CUL-67)
L. gasseri (CUL-09)
B. animalis subsp. lactis(CUL-62)
B. breve (CUL-74)
S. salivarius subsp. thermophilus
(CUL-68)
L. acidophilus (NCFM™)
B. animalis subsp. lactis (HN019)
L. rhamnosus (HN001)
L. acidophilus (CUL-60)
L. acidophilus (CUL- 21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. acidophilus (CUL-60)
L. acidophilus (CUL- 21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
HMF Replenish
Capsules
Highest potency probiotic
capsule for intensive use
100 billion
Yes
HMF Replete
(powder)
Highest potency probiotic
powder for intensive use
150 billion per
sachet
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. salivarius (CUL-61)
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. salivarius (CUL-61)
PRODUCT
PRIMARY INDICATIONS
MAINTENANCE
HMF
Pre + Probiotic
(powder)
Yes
Yes
No
No
Yes
Adults and Adolescents (12 years and older): In a glass,
add eight ounces (250 ml) of water or juice to two scoops
of HMF Pre + Probiotic and mix. Take two times daily, at
least two to three hours before or after taking antibiotics or
other medications, or as recommended by your healthcare
practitioner. Drink a full glass of liquid with each serving.
When used as a gentle laxative, effects are observed twelve
to twenty-four hours after first dose, and may take two to
three days.
Adults and Children (6 years and older): Take two
capsules two times daily with meals, at least two to
three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
Adults and Children (6 years and older): Take one
capsule two times daily with meals, at least two to
three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
Adults and Children (1 year and older):
In a glass, add water or milk to one scoop
(¼ teaspoon) of HMF Super Powder and mix. Take two
times daily with meals, at least two to three hours before
or after taking antibiotics, or as recommended by your
healthcare practitioner.
Adults and Children (1 year and older):
In a glass, add water or milk to one scoop
(¼ teaspoon) of HMF Powder and mix. Take two times
daily with meals, at least two to three hours before or after
taking antibiotics, or as recommended by your healthcare
practitioner.
Adults, Adolescents and Children (6 years and
older): Take one capsule daily, at least two to
three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
Adults and Children (6 years and older): Take one
capsule daily with a meal, at least two to three hours
before or after taking antibiotics, or as recommended
by your healthcare practitioner.
Adults, Adolescents and Children (3 years and
older): In a glass, add water or milk to one scoop of
HMF Intensive Powder and mix. Take once daily with a
meal, at least two to three hours before or after taking
antibiotics, or as recommended by your healthcare
practitioner.
Adults and Children (6 years and older): Take one
capsule daily with a meal, at least two to three hours
before or after taking antibiotics, or as recommended
by your healthcare practitioner.
Adults: In a glass, add water to ½ sachet of
HMF Replete and mix. Take once daily with a
meal, at least two to three hours before or after taking
antibiotics, or as recommended by your healthcare
practitioner.
PRODUCT
PRIMARY INDICATIONS
CFU PER
DOSAGE UNIT STRAINS
IBS SYMPTOMS
HMF IBS Relief
(capsules)
25 billion
Clinically proven to
significantly reduce
symptoms of Irritable Bowel
Syndrome (IBS)
POST ANTIBIOTIC CARE
100 billion
HMF Antibiotic Care
Clinically proven to
(capsules)
supplement the normal
intestinal microbiota
following antibiotic therapy
EXORPHIN DEGRADING (in vitro)
HMF
Exorphin degrading capacity 12 billion
Neuro Capsules
in intestinally-simulated
conditions
HMF
Neuro Powder
Exorphin degrading capacity 12 billion
in intestinally-simulated
conditions
OTHER ACTIVE
INGREDIENTS
FOS RECOMMENDED DOSE
L. acidophilus (CUL-60)
L. acidophilus (CUL- 21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
No
Adults and Children (11 years and older): Take one
capsule daily with a meal, at least two to three hours
before or after taking antibiotics, or as recommended
by your healthcare practitioner.
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. salivarius (CUL-61)
Yes
Adults and Children (6 years and older): Take one
capsule daily with a meal, at least two to three hours
before or after taking antibiotics, or as recommended
by your healthcare practitioner.
Adults, Adolescents and Children (6 years and
older): Take one capsule two times daily with meals,
at least two to three hours before or after taking
antibiotics, or as recommended by your healthcare
practitioner.
Adults: In a glass, add water to one scoop
(¼ teaspoon) of HMF Neuro Powder and mix. Take two
times daily with meals, at least two to three hours
before or after taking antibiotics, or as recommended by
your healthcare practitioner.
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. rhamnosus (CUL-63)
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. rhamnosus (CUL-63)
L-Glutamine
No
L-Glutamine
Yes
URINARY SUPPORT
HMF Cystgen
Helps to prevent recurrent
(powder)
urinary tract infections
(UTIs)
10 billion
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
Vitamin C, potassium,
cranberry fruit juice
concentrate
No
Adults: Take ¼ sachet four times daily or as recommended
by your healthcare practitioner. Take with food or
immediately after meals. Completely dissolve powderin
¼ glass of cold water or juice. Allow fizzing to stop before
drinking. Take at least two to three hours before or after
taking antibiotics. For optimal effect, use for a minimum
of four weeks.
YEAST INFECTION SUPPORT
HMF
Supports healthy microflora
Candigen Cream
100 million
L. acidophilus (CUL-60)
L. gasseri (CUL-09)
Garlic powder
No
HMF Candigen
Supports healthy microflora 200 million
(ovules)
PREGNANC Y AND CHILD SUPPORT
HMF
Supports children
2.5 billion
Toddler + Pro
(powder)
L. acidophilus (CUL-60)
L. gasseri (CUL-09)
Garlic powder
No
Application: Apply a thin layer of cream to the external
vaginal area two to three times daily, or as recommended
by your healthcare practitioner. For external use only.
Adults: Use one ovule per day at bedtime or as
recommended by your healthcare practitioner.
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. salivarius (CUL-61)
L. paracasei (CUL-08)
Transgalactooligosaccharides,
multivitamin blend
Yes
HMF Natogen
(powder)
Probiotic specifically
formulated for breast-fed
children
3 billion
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
L. paracasei (CUL-08)
B. animalis subsp. lactis (CUL-62)
NEW
HMF Baby B
Probiotic supplement for
breast fed babies
10 billion
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. salivarius (CUL-61)
L. paracasei (CUL-08)
Galacto-oligosaccharides
(GOS)
Yes
NEW
HMF Baby F
Probiotic supplement for
formula fed babies
10 billion
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. salivarius (CUL-61)
L. paracasei (CUL-08)
Transgalacto
oligosaccharides (GOS)
(from milk)
Yes
HMF Maternity
(capsules)
Supports pregnant women
10 billion
HMF
Maternity + Pro
(capsules + softgels)
Supports pregnant women
10 billion
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. salivarius (CUL-61)
L. paracasei (CUL-08)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. salivarius (CUL-61)
L. paracasei (CUL-08)
HMF Child
(chewable tablets)
Child-specific high potency
chewable probiotic
12.5 billion
L. acidophilus (CUL-60)
L. acidophilus (CUL-21)
B. bifidum (CUL-20)
B. animalis subsp. lactis (CUL-34)
L. salivarius (CUL-61)
L. paracasei (CUL-08)
No
No
Multivitamin and mineral
blend, fish oil with
beta carotene and vitamin E
No
No
Children (1-5 years): In a glass, add water or milk to
one scoop of HMF Toddler + Pro and mix. Take once
daily with a meal, at least two to three hours before
or after taking antibiotics, or as recommended by your
healthcare practitioner.
Children (1-4 years): In a glass, add water or milk to
one scoop of powder and mix. Take once daily with a
meal, at least two to three hours before or after taking
antibiotics, or as recommended by your healthcare
practitioner.
Children (1-4 years): In a glass, add water or milk to
one scoop of HMF Baby B and mix. Take once daily
with a meal, at least two to three hours before or
after taking antibiotics, or as recommended by your
healthcare practitioner.
Children (1-4 years): In a glass, add water or milk to
one scoop of HMF Baby F and mix. Take once daily with
a meal, at least two to three hours before or after taking
antibiotics, or as recommended by your healthcare
practitioner.
Women: Take one capsule daily with
a meal, at least two to three hours before or after
taking antibiotics, or as recommended by your
healthcare practitioner.
Women (19 years and older): Take one serrated strip,
containing one capsule and one softgel, once daily with a
meal or as recommended by your healthcare practitioner.
Take a few hours before or after taking other medications,
and at least two to three hours before or after taking
antibiotics.
Children (4 years and older): Chew one tablet two
times daily with meals, or as recommended by your
healthcare practitioner.
9
EXORPHIN-DEGRADING (in vitro)
URINARY SUPPORT
HMF Neuro Capsules
HMF Neuro Powder
HMF Cystgen
PROBIOTIC FORMULA
PROBIOTIC FORMULA
PROBIOTIC FORMULA
Moderate level probiotic
• 12 billion CFU per dose
• Includes L-glutamine
Ideal for vegans
•Convenient vegetable capsule format
Moderate level probiotic
• 12 billion CFU per dose
• Includes L-glutamine and fructooligosaccharides
Ideal for vegans
•Convenient powder format
HMF Neuro Capsules is a unique preparation containing various
strains and species of proprietary human-sourced Lactobacillus
and Bifidobacteria to help maintain the integrity and health of
the intestinal tract.
HMF Neuro Powder is a unique preparation containing various
strains and species of proprietary human-sourced Lactobacillus
and Bifidobacteria to help maintain the integrity and health of
the intestinal tract.
EACH CAPSULE CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 12 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus rhamnosus (CUL-63)
L-Glutamine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 mg
EACH SCOOP (1 g) CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 12 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus rhamnosus (CUL-63)
L-Glutamine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 500 mg
Fructooligosaccharides (FOS) . . . . . . . . . . . . . . . . . . . . . . . 250 mg
Non-Medicinal Ingredients: Hypromellose, silica, magnesium
stearate
Non-Medicinal Ingredient: Apricot powder
Recommended Dose: Adults, Adolescents and Children
(6 years and older): Take one capsule two times daily
with meals, at least two to three hours before or after
taking antibiotics, or as recommended by your healthcare
practitioner.
Recommended Adult Dose: In a glass, add water to one
scoop (¼ teaspoon) of HMF Neuro Powder and mix. Take
two times daily with meals, at least two to three hours before
or after taking antibiotics, or as recommended by your
healthcare practitioner.
60 Vegetable Capsules
60 g Powder
NPN 80039135
Product Code: 10442
NPN 80038853
Product Code: 10443
Moderate level probiotic
•10 billion CFU per sachet
Concentrated cranberry juice extract
•Prevents urinary tract infections (UTIs)
•Each sachet provides the quivalent
to 30 g of fresh cranberry juice
HMF Cystgen provides two strains of Lactobacillus formulated
for the support and maintenance of a healthy gut microflora.
Cranberry juice extracts prevent urinary tract iInfections (UTIs)
and are a source of antioxidants.
EACH SACHET (7.5 g) CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 10 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Vitamin C (ascorbic acid) . . . . . . . . . . . . . . . . . . . . . . . . . . . 600 mg
Potassium (potassium citrate/ bicarbonate) . . . . . . . . 1515 mg
Cranberry (Vaccinium macrocarpon)
Fruit Juice Concentrate (36:1). . . . . . . . . . . . . . . . . . . . . . 833 mg
30 g Fresh Equivalent
Non-Medicinal Ingredients: Cellulose, citric acid
Recommended Adult Dose: Take ¼ sachet four times daily
or as recommended by your healthcare practitioner. Take
with food or immediately after meals. Completely dissolve
powder in ¼ glass of cold water or juice. Allow fizzing to stop
before drinking. Take at least two to three hours before or
after taking antibiotics. For optimal effect, use for a minimum
of four weeks.
6 x 7.5 g Sachets of Powder (45 g) Product Code: 10413
NPN 80037490
10
YEAST INFECTION SUPPORT
PREGNANCY & CHILD SUPPORT
HMF Candigen Cream
HMF Candigen
HMF Maternity
PROBIOTIC CREAM
PROBIOTIC SUPPOSITORIES
PROBIOTIC FORMULA
Female probiotic cream
•100 milllion CFU per gram
•Includes garlic powder and Rosa damascena flower oil
HMF Candigen Cream provides two strains of Lactobacillus. One
gram (1 g) of cream contains 80 million CFU of Lactobacillus
acidophilus and 20 million CFU of Lactobacillus gasseri, in
combination with 2.47 mg of garlic (Allium sativum) clove
powder. For maximum benefit, HMF Candigen Cream should
be used along with HMF Candigen probiotic suppositories.
Ingredients: PEG-8, PEG-32, Lactobacillus Ferments
[Lactobacillus acidophilus (CUL-60); Lactobacillus gasseri
(CUL-09)], Allium Sativum (Garlic) Bulb Powder, Rosa
Damascena Flower Oil
Recommended Application: Apply a thin layer of cream
to the external vaginal area two to three times daily, or as
recommended by your healthcare practitioner. For external
use only.
50 g
NPN 80037490
Product Code: 10566
Female probiotic suppositories
• 200 million CFU per dose
• Includes garlic bulb extract and Rosa damascena flower oil
Ideal for vegans
• Convenient ovule format
HMF Candigen is presented as vaginal ovules which provide two
strains of Lactobacillus. For maximum benefits, HMF Candigen
should be used along with HMF Candigen Cream.
Ingredients: PEG-12, PEG-150, Lactobacillus Ferments
[Lactobacillus acidophilus (CUL-60)], Lactobacillus gasseri
(CUL-09), Allium Sativum (Garlic) Bulb Extract, Rosa Damascena
Flower Oil
Recommended Adult Use: Use one ovule per day at
bedtime or as recommended by your healthcare practitioner.
Remove ovule from blister pack and place into top of
applicator. Stand, squat or lie on your back with knees bent.
Holding the loaded applicator, gently insert into the vagina
as far as it will comfortably go. Holding the barrel of the
applicator steady, gently depress the plunger until it stops to
release the ovule in the vagina. Remove the applicator. Clean
the applicator after each use with soap and warm water and
rinse thoroughly.
6 Vaginal Ovules
Product Code: 10568
Probiotic support for pregnant women
•Clinically proven to be safe during pregnancy 1
• Source of probiotics that temporarily modify gut flora
• 10 billion CFU per dose
Expectant mothers may have safety concerns about using
probiotics during pregnancy. HMF Maternity’s probiotic
formulation is based on recent clinical safety evidence: in a
double-blind, placebo-controlled clinical trial conducted on
454 pregnant women, supplementation with HMF Maternity’s
probiotic combination did not increase adverse event risk,
when compared to placebo treatment.1
EACH CAPSULE CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . 10 billion CFU
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus salivarius (CUL-61)
Lactobacillus paracasei (CUL-08)
Non-Medicinal Ingredients: Maltodextrin, hypromellose
Recommended Dose: Women: Take one capsule daily
with a meal, at least two to three hours before or after
taking antibiotics, or as recommended by your healthcare
practitioner.
30 Vegetable Capsules
Product Code: 10492
NPN 80039564
1. Allen SJ et al. Dietary Supplementation with Lactobacilli and Bifidobacteria Is Well Tolerated and Not
Associated with Adverse Events during Late Pregnancy and Early Infancy. The Journal of Nutrition. 2010;
140: 483–488
11
PREGNANCY & CHILD SUPPORT
HMF Maternity + Pro
HMF Child
VITAMIN SUPPLEMENT WITH HMF
(HUMAN MICROFLORA) PROBIOTICS
Nutritional and probiotic supplement
for pregnant women
•Includes the 4 major foundations of nutrition; vitamins and
minerals, antioxidants, clinically proven human-sourced
probiotics and omega-3 essential fatty acids
• Uses probiotic strains that are clinically proven to be
safe during pregnancy1
• 10 billion CFU per dose
• Provides folate, to reduce the risk of neural tube
defects when taken during early pregnancy
Includes high DHA fish oil
•Each softgel provides 200 mg of DHA (docosahexaenoic acid)
to help support cognitive health and brain function
Convenient & cost-effective combination
•Each package provides 28 easy-to-use portable strips
(containing 1 vegetable capsule and 1 softgel per strip)
HMF Maternity + Pro is a nutritional and probiotic supplement
for pregnant women. Each dose of HMF Maternity + Pro
provides 10 billion CFU of probiotic strains that are clinically
proven to be safe during pregnancy,1 plus 20 vitamins and
minerals, antioxidants, and 200 mg of DHA. HMF Maternity +
Pro supports the development of brain, eyes, and nerves, and
helps to the risk of neural tube defects when taken during
early pregnancy.
PROBIOTIC FORMULA
EACH VEGETABLE CAPSULE CONTAINS:
Vitamin C (ascorbic acid) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150 mg
Vitamin D (cholecalciferol). . . . . . . . . . . . . . . . . . . . . . . . . 25 mcg / 1000 IU
Vitamin K1 (phylloquinone). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 mcg
Thiamine (thiamine mononitrate). . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.2 mg
Riboflavin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.8 mg
Niacinamide. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 mg
Vitamin B6 (pyridoxine hydrochloride). . . . . . . . . . . . . . . . . . . . . . . . . 2.8 mg
Folate (folic acid). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 800 mcg
Vitamin B12 (cyanocobalamin). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 mcg
Biotin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 mcg
Pantothenic Acid (calcium d-pantothenate). . . . . . . . . . . . . . . . . . . . 12 mg
Calcium (calcium carbonate). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120 mg
Iron (ferrous fumarate). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 mg
Iodine (potassium iodide). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150mcg
Magnesium (magnesium oxide) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56.25 mg
Zinc (zinc citrate). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 mg
Selenium (selenomethionine). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 mcg
Copper [copper (II) citrate]. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1000 mcg
Manganese (manganese gluconate) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 mg
Chromium [chromium (III) polynicotinate]. . . . . . . . . . . . . . . . . . . . . . 40 mcg
Molybdenum [sodium molybdate (VI)]. . . . . . . . . . . . . . . . . . . . . . . . . 50 mcg
N-Acetyl-L-Cysteine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 mg
Probiotic Consortium. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 billion CFU
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus salivarius (CUL-61)
Lactobacillus paracasei (CUL-08)
Non-Medicinal Ingredients: Hypromellose, silica, magnesium stearate
EACH SOFTGEL CAPSULE CONTAINS:
Fish Oil (Tuna). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625 mg
Yielding
DHA (Docosahexaenoic Acid). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200 mg
EPA (Eicosapentaenoic Acid). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 mg
Beta-carotene. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2400 mcg
Vitamin E (d-alpha tocopheryl acetate). . . . . . . . . . . . . 10 mg AT / 15 IU
Non-Medicinal Ingredients: Fish gelatin, glycerin
Recommended Dose: Women (19 years and older):
Take one serrated strip, containing one capsule and one
softgel, once daily with a meal or as recommended by your
healthcare practitioner. Take a few hours before or after taking
other medications, and at least two to three hours before or
after taking antibiotics.
28 Vegetable Capsules + 28 Softgel Capsules
Product Code: 03168
NPN 80043419
1.Allen SJ et al. Dietary Supplementation with Lactobacilli and Bifidobacteria Is Well Tolerated and
Not Associated with Adverse Events during Late Pregnancy and Early Infancy. The Journal of
Nutrition. 2010; 140: 483–488
12
Moderate level probiotic ideal for children
• Contributes to a natural healthy gut flora
• 12.5 billion CFU per dose
• Natural blackcurrant-flavoured chewable tablet
HMF Child probiotic formula is a moderate level probiotic
combination providing Lactobacillus acidophilus,
Bifidobacterium bifidum, Lactobacillus paracasei, Lactobacillus
salivarius and Bifidobacterium animalis subsp. lactis, which help
support a healthy gut flora in children.
EACH TABLET CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . 12.5 billionCFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus salivarius (CUL-61)
Lactobacillus paracasei (CUL-08)
Non-Medicinal Ingredients: Sorbitol, xylitol, natural
blackcurrant flavour, silica, magnesium stearate
Recommended Dose: Children (4 years and older):
Chew one tablet two times daily with meals, at least two
to three hours before or after taking antibiotics, or as
recommended by your healthcare practitioner.
30 Chewable Tablets
NPN 80020665
Product Code: 10451
PREGNANCY & CHILD SUPPORT
HMF Baby B
PROBIOTIC FORMULA
HMF Baby F
PROBIOTIC FORMULA
PROBIOTIC FORMULA
Probiotic supplement for breast fed babies
•Safe for use during infancy
•A recent clinical trial found that this probiotic formula safely
and effectively reduced atopic eczema incidence and skin
prick reaction to common allergens in infants1
•10 billion CFU per dose
•Helps support gastrointestinal health
•Promotes a favourable gut flora
Probiotic supplement for formula fed babies
•Safe for use during infancy
•A recent clinical trial found that this probiotic formula safely
and effectively reduced atopic eczema incidence and skin
prick reaction to common allergens in infants1
•10 billion CFU per dose
•Helps support gastrointestinal health
•Promotes a favourable gut flora
HMF Baby B probiotic supplement for breast fed babies provides
Lactobacillus salivarius, Lactobacillus paracasei, Bifidobacterium
bifidum and Bifidobacterium animalis subsp. lactis, which help
to support intestinal/gastrointestinal health. Infant microflora
composition also influences early immune development, and
may impact risk of developing atopic disease.
HMF Baby F probiotic supplement for formula fed babies
provides Lactobacillus salivarius, Lactobacillus paracasei,
Bifidobacterium bifidum and Bifidobacterium animalis subsp.
lactis, which help to support gastrointestinal health. Infant
microflora composition also influences early immune
development, and may impact risk of developing atopic disease.
HMF Baby B powder dissolves easily into milk, breast milk,
or water.
HMF Baby F contains galactooligosaccharides (GOS), a type of
prebiotic fiber found naturally within breast milk that may help
to support a healthy gastrointestinal microflora.2
Fructooligosaccharides (FOS) are also included for additional
prebiotic fiber content.2 HMF Baby F powder dissolves easily
into milk or water.
EACH SCOOP (200 mg) CONTAINS:
Probiotic Consortium. . . . . . . . . . . . . . . . . . . . . . . 10 billion CFU
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus salivarius (CUL-61)
Lactobacillus paracasei (CUL-08)
Non-Medicinal Ingredients: Transgalactooligosaccharides
(GOS) (from milk)
Contains: Milk
Recommended Dose: Children (1-4 years): In a glass,
add water or milk to one scoop of HMF Baby B and mix.
Take once daily with a meal, at least two to three hours
before or after taking antibiotics, or as recommended by
your healthcare practitioner.
Product Size: 6g Powder
Product Code: 10491
NPN 80048579
EGETARIAN
1. Allen SJ et al. Probiotics in the prevention of eczema: a randomized controlled trial. Arch. Dis. Child. 2014;
99(11): 1014-1019
HMF Natogen
EACH SCOOP (1.1 g) CONTAINS:
Probiotic Consortium. . . . . . . . . . . . . . . . . . . . . . . . 10 billion CFU
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus salivarius (CUL-61)
Lactobacillus paracasei (CUL-08)
Low level probiotic
•3 billion CFU per dose
Easy-to-use
•Add 1 scoop (100 mg) to milk or water
HMF Natogen child probiotic formula provides Lactobacillus
acidophilus, Lactobacillus paracasei and Bifidobacterium animalis
subsp. lactis, which contribute to a healthy intestinal microflora
in children (1-4 years).
EACH SCOOP (100 mg) CONTAINS:
Probiotic Consortium . . . . . . . . . . . . . . . . . . . . . . . . 3 billion CFU
Lactobacillus acidophilus (CUL-60)
Lactobacillus acidophilus (CUL-21)
Lactobacillus paracasei (CUL-08)
Bifidobacterium animalis subsp. lactis (CUL-62)
Non-Medicinal Ingredient: Lactose monohydrate (milk)
Recommended Dose: Children (1-4 years):
In a glass, add water or milk to one scoop of HMF Natogen
and mix. Take once daily with a meal, at least two to three
hours before or after taking antibiotics, or as recommended by
your healthcare practitioner.
6 g Powder
Product Code: 10424
NPN 80014287
EGETARIAN
Non-Medicinal Ingredients: Transgalactooligosaccharides
(GOS) (from milk), fructooligosaccharides (FOS)
Contains: Milk
30 Vegetable Capsules
Product Code: 10493
Recommended Dose: Children (1-4 years): In a glass,
add water or milk to one scoop of HMF Baby F and mix.
Take once daily with a meal, at least two to three hours
before or after taking antibiotics, or as recommended by
your healthcare practitioner.
NPN 80048547
EGETARIAN
1. Allen SJ et al. Probiotics in the prevention of eczema: a randomized controlled trial. Arch. Dis. Child. 2014;
99: 11 1014-1019
2. Jeurink P, van Esch B, Rijnierse A, Garssen J, and Knippels L. Mechanisms underlying immune effects of
dietary oligosaccharides. American Journal of Clinical Nutrition. 2013; 98(suppl.): 572S–577S
13
PREGNANCY & CHILD SUPPORT
HMF Toddler + Pro
VITAMIN SUPPLEMENT WITH HMF
(HUMAN MICROFLORA) PROBIOTICS
Vitamin and probiotic combination for toddlers
• Includes vitamins, minerals, antioxidants and clinically
proven human-sourced probiotics
• Supports normal growth and development
• Helps to maintain eyesight, skin, membranes
and immune function
• Provides 2.5 billion CFU of probiotics that promote
a favourable microflora composition
• Added GOS and FOS prebiotic fibres support
gastrointestinal microflora
• Great-tasting berry flavour
HMF Toddler + Pro supports pediatric nutrition and intestinal
health with a unique consortium of human-sourced probiotic
strains, plus over 10 vitamins. Vitamins A, C, D, and K support
the development and maintenance of bones, cartilage, teeth
and gums. Red blood cell formation and macronutrient
metabolism are supported with vitamins B1, B2, B3, B5, B6, biotin,
folate and B12.
EACH SCOOP (1 g) CONTAINS:
Vitamin A (vitamin A acetate). . . . . . . 400 mcg RAE / 1333 IU
Vitamin C (ascorbic acid) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 mg
Vitamin D (cholecalciferol). . . . . . . . . . . . . . . . . . 5 mcg / 200 IU
Vitamin E (d-alpha tocopheryl acetate). . . . . . . 6 mg AT / 9 IU
Vitamin K1 (phylloquinone) . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 mcg
Thiamine (thiamine mononitrate). . . . . . . . . . . . . . . . . . . 0.55 mg
Riboflavin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 0.7 mg
Niacinamide. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 mg
Vitamin B6 (pyridoxine hydrochloride). . . . . . . . . . . . . . . . 0.7 mg
Folate (folic acid). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 mcg
Vitamin B12 (methylcobalamin). . . . . . . . . . . . . . . . . . . . . . 1.25 mcg
Biotin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 mcg
Pantothenic Acid (calcium d-pantothenate). . . . . . . . . . . . 3 mg
Probiotic Consortium. . . . . . . . . . . . . . . . . . . . . . . 2.5 billion CFU
Bifidobacterium bifidum (CUL-20)
Bifidobacterium animalis subsp. lactis (CUL-34)
Lactobacillus salivarius (CUL-61)
Lactobacillus paracasei (CUL-08)
Non-Medicinal Ingredients: Fructooligosaccharides
(FOS), transgalactooligosaccharides, fruit blend (strawberry,
blackberry, blackcurrant, bilberry, elderberry), xylitol, natural
strawberry flavour
Contains: Milk
Recommended Dose: Children (1-5 years):
In a glass, add water or milk to one scoop of HMF Toddler +
Pro and mix. Take once daily with a meal, at least two to three
hours before or after taking antibiotics, or as recommended by
your healthcare practitioner.
60 g Powder
NPN 80039780
EGETARIAN
14
Product Code: 03169
HMF Probiotic Clinical Trials
The Swansea Baby Trial
Probiotics in the Prevention of Eczema: A Randomised Controlled Trial
(Allen at al. 2014)
The probiotic formula that is used in GENESTRA BRANDS HMF
Baby B and HMF Baby F was found to safely and effectively
reduce atopic eczema incidence and skin prick sensitivity to
common allergens in infants. In a randomized, double-blind,
placebo-controlled, parallel group trial, 454 pregnant women at 36
weeks of gestation were assigned to either the probiotic capsule
treatment group (Lactobacillus salivarius CUL61 6.25×109 colony
forming units (CFUs), Lactobacillus paracasei CUL08 1.25×109 CFU,
Bifidobacterium animalis subsp. lactis CUL34 1.25×109 CFU and
Bifidobacterium bifidum CUL20 1.25×109 CFU) or the placebo capsule
treatment group. Participants began daily supplementation with
either treatment until giving birth; participants’ infants then began
daily supplementation until 6 months of age. At 6 months and 2
Atopic Eczema at 2 Years
Percent
Placebo Group
12.10%
HMF Probiotic Group
5.30%
years of age, skin prick testing (SPT) was performed using common
food allergens (cow’s milk, hen’s egg). The presence of atopic eczema
was determined based upon the presence of one or more positive
SPTs. In comparison with the infant participants in the placebo
group, participants in the probiotic group experienced a statistically
significant 57% decrease in atopic eczema. Participants in the
probiotic group also experienced a significant 44% decrease in skin
prick sensitivity to common food allergens.
•57% decrease in atopic eczema
•
44% decrease in skin prick sensitivity
to food allergens
ReducedAAtopic
22
Years
in Probiotic
Group
Reduced topic EEczema
czema atat Years in Probio7c Group 14.00% 12.00% 10.00% *
8.00% 6.00% 4.00% 2.00% 0.00% Placebo
Group
Placebo Group ProbioticGGroup
Probio6c roup * p < 0.05
15
SPT positive at 6 m
Total
Cow's Milk Protein
Egg Protein
Placebo Group
10.88%
3.40%
9.50%
Probiotic Group
3.97%
0%
3.40%
Fewer
Prick Text
TestScores
Scoresatat66Months
MonthsininProbiotic
Priobiotic
Group
FewerPositive
Positive Skin
Skin Prick
Group
12.00% 10.00% 8.00% Placebo Group ProbioAc Group 6.00% *
*
4.00% 2.00% *
0.00% 16
Total
Total Cow’s
Milk
Protein
Cow's Milk Protein EggPProtein
Egg rotein * p < 0.05
The ProChild Study
Probiotics and Vitamin C for the Prevention of Respiratory Tract Infections
in Children Attending Preschool: A Randomised Controlled Pilot Study
(Garaiova at al. 2014)
The probiotic formula used in several GENESTRA BRANDS HMF
products, in combination with vitamin C, was found to significantly
reduce incidence of upper respiratory tract infections (URTI) in
preschool children. The number of days with URTI symptoms,
school absenteeism, and usage of cough medication were also
significantly reduced. In a 6 month long, randomized, double-blind,
placebo-controlled study, 57 preschool children aged 3-6 were randomized
to either the placebo tablet group or the probiotic and vitamin C tablet
group (12.5 billion CFU of Lactobacillus acidophilus CUL60 and CUL 21,
Bifidobacterium animalis subsp. lactis CUL34, and Bifidobacterium bifidum
CUL20). The URTI symptoms evaluated included sneezing, sore throat,
cough, runny and blocked nose. Compared with the placebo group, the
children in the probiotic group had 33% less incidence of URTI, a significant
decrease in the number of days with URTI symptoms, a 30% decrease in
school absenteeism incidence rate, and a significant reduction in cough
medication usage.
•
33% less incidence of upper respiratory
tract infections (URTI)
•Significantly fewer days with URTI symptoms
•30% less school absenteeism
•Significant reduction in cough medication usage
URTI symptoms
Placebo Group
HMF Probiotic Group
Mean Days with URTI Symptoms
43.1
22.1
Decreased
Mean
Days
With URTI
URTI Symptoms
in Probiotic
Group Group
Decreased
Mean
Days
With
Symptoms
in Probiotic
45 40 35 *
30 25 20 15 10 5 0 Placebo Group
Probiotic
Group
Probiotic
Group
* p < 0.05
17
Individual URTI Symptoms - Cough
Placebo Group
HMF Probiotic Group
Mean days With Cough Symptoms
23.5
11.9
Decreased
Days
WithCough
Cough Symptoms
in Probiotic
Group Group
Decreased
MeanMean
Days
With
Symptoms
in Probiotic
25 20 *
15 10 5 0 PlaceboGroup
Group
Placebo
ProbioticGroup
Group
Probiotic
* p < 0.05
Individual URTI Symptoms - Sneezing
Placebo Group
HMF Probiotic Group
Mean Days With Sneezing Symptoms
9.6
2.3
Decreased
Mean Days
With
Sneezing Symptoms
in Probiotic
Group Group
Decreased
Mean Days
With
Sneezing
Symptoms
in Probiotic
10 9 8 7 6 5 *
4 3 2 1 0 18
Placebo
PlaceboGroup
Group
Probiotic
ProbioticGroup
Group
* p < 0.05
The Sheffield IBS Trial
Clinical Trial: A Multistrain Probiotic Preparation Significantly Reduces Symptoms
of Irritable Bowel Syndrome in a Double-Blind Placebo-Controlled Study
(Williams et al. 2008)
The probiotic formula that is used in GENESTRA BRANDS
HMF IBS Relief was found to decrease the severity of IBS
symptoms and number of days with pain, while improving
satisfaction with bowel habits and overall quality of life. This
8-week long, double-blind, randomized, placebo-controlled study
was conducted in 52 participants diagnosed with IBS, as defined
by the Rome II Criteria. Participants were randomized to either the
placebo capsule treatment group or the probiotic capsule group
(2.5x1010 CFU from Lactobacillus acidophilus CUL60 and CUL 21,
Bifidobacterium animalis subsp. lactis CUL34, and Bifidobacterium
bifidum CUL20). Participants scored their IBS symptom severity
(including bloating, satisfaction with bowel habits, number of days
with pain, quality of life, and abdominal pain) at baseline and every
2 weeks during supplementation. In comparison with the placebo
group, a significantly greater improvement in total IBS symptoms
was observed in participants in the probiotic treatment group
throughout the 8 week supplementation period. In the probiotic
group, satisfaction with bowel habits was significantly improved in
just 6 weeks, and quality of life scores were improved after 8 weeks of
supplementation.
•
Significantly improved IBS Symptom Severity Scores
•
22% decrease in days with pain
•
32% improvement in satisfaction with bowel habits
IBS Symptom Severity Scores
IBS Relief Group
Placebo Group
Before Supplementation
73.39
252.08
At 8 Weeks of Probiotic Supplementation
39.65
172
% Change at Week 8
133.39
80.66
Probiotic
SupplementationReduces
ReducesIBS
Probiotic
Supplementation
IBS
Symptom
SeverityScores
Scores
Symptom
Severity
300 250 *
200 150 100 Before Supplementation
Before Supplementation
At 8 Weeks of Probiotic
At 8 Weeks of Probiotic
Supplementation
Supplmentation
* p < 0.05
19
The Cambridge Probiotic / Antibiotic Trial
Effect of Probiotics on Preventing Disruption of the Intestinal Microflora
Following Antibiotic Therapy: A Double-Blind, Placebo-Controlled Pilot Study
(Plummer et al. 2005)
The probiotic formula that is used in GENESTRA BRANDS
HMF Antibiotic Care was found to minimize disruption of the
intestinal micobiota following antibiotic therapy and prevent the
development of antibiotic resistance. This 5-week long, double-blind
placebo-controlled study was conducted in 162 participants infected
with Helicobacter pylori that were receiving a triple therapy antibiotic
treatment regimen. Participants received antibiotic therapy for days
1-7 of the study, and probiotic or placebo therapy for days 1-21. The
probiotic capsule contained 2.5×1010 CFU from Lactobacillus acidophilus
CUL60 and CUL21, and two strains of Bifidobacterium. Fecal samples
were obtained at days 1, 7 and 35, and then analyzed for bacterial
composition and bacterial strain antibiotic resistance. Compared with the
placebo group, significantly fewer participants in the probiotic treatment
group had enterococci bacteria resistant to amoxicillin. Probiotic
supplementation helped significantly reduce overgrowth of potentially
harmful facultative anaerobic bacteria, including coliforms, enterococci
and Staphylococcus aureus. As well, probiotic supplementation helped
to minimize the loss of lactobacilli bacteria: the level of lactobacilli was
significantly lowered in the placebo group following antibiotic therapy,
but not in the probiotic treatment group.
•
Significant reduction in antibiotic resistance
•
Decreased overgrowth of coliforms, enterococci and
Staphylococcus aureus bacteria
•Prevented loss of lactobacilli bacteria
The Swansea ‘Safety in Newborns’ Study
Dietary Supplementation with Lactobacilli and
Bifidobacteria is Well Tolerated and
Not Associated with Adverse Events During Late
Pregnancy and Early Infancy
(Allen at al. 2010)
The probiotic formula that is used in GENESTRA BRANDS HMF
Baby B and HMF Baby F was found to be safe for use by pregnant
mothers at 36+ weeks of gestation and in infants aged 0-6
months. Probiotic supplementation did not impact adverse event
incidence, number of visits to the doctor, or mothers’ assessment of
infant health. Based on these findings, the authors concluded that usage
of the probiotic formula was safe during pregnancy and infancy.
•
No increase in adverse event incidence in pregnant mothers
•No increase in adverse event incidence in infants
20
Notes
21
A trusted Seroyal brand.
To order, call:
1-800-263-5861
[email protected]
For more information, visit:
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