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2015 Recipients of the Award Joshua Milner, Bethesda, MD, US USD 50 000 2014 Recipients of the Award Stephan Weidinger, Kiel, Germany USD 50 000 2013 Recipients of the Award Kenji Kabashima, Kyoto, Japan USD 50 000 2012 Recipients of the Award Elizabeth Matsui, Baltimore, MD, US USD 50 000 2011 Recipients of the Award Valérie Julia, Valbonne, France Susumu Nakae, Tokyo, Japan Recipients of an Honourable Mention Sarbjit Singh Saini, Baltimore, Maryland, US Claudia Traidl-Hoffmann, Munich, Germany USD 25 000 USD 25 000 2010 Recipients of the Award Christopher Kepley, Danville, US Nicholaos Papadopoulos, Athens, Greece USD 25 000 USD 25 000 2009 - 1st year of nomination procedure Recipients of the Award Hamida Hammad, Ghent, Belgium Recipients of an Honourable Mention Alan Irvine, Dublin,Ireland Matthew Perzanowski, New York, USA USD 50 000 2008 - Subject: New insights into the mechanisms and management of allergic disease Recipients of the Award Natalija Novak Bonn, Germany New insights into the mechanism and manage-ment of allergic diseases: atopic dermatitis USD 50 000 2007 - Subject: Impact of allergy – from mechanisms to treatment Recipients of the Award Graham Ogg Oxford, UK Susanne Vrtala Vienna, Austria Impaired maturation of T-cell responses to allergens; impact on atopic disease From allergen genes to new forms of allergy diagnosis and treatment USD 25 000 USD 25 000 2006 - Subject: New insights into mechanisms and management of allergic diseases Recipients of the Award Barbara Bohle The impact of pollen-related food allergens on pollen USD 50 000 Vienna, Austria allergy Recipient of an Honourable Mention Graham Ogg A role for DC8+T cells in the mechanisms and treatment of allergic Oxford, UK disease Susanne Vrtala Genetic engineering of allergens for immunotherapy and elucidation Vienna, Austria of mechanisms in allergy 2005 - Subject: Advances in the understanding and treatment of allergic diseases Recipients of the Award Omid Akbari CD4+ iNKT cells; New target for treatment of asthma USD 50 000 Boston, MA, USA in human Recipients of an Honourable Mention Verena Niederberger The transition of recombinant allergens from the bench into clinical Vienna, Austria applications Barbara Bohle Basic mechanisms operative in pollen-related food allergy Vienna, Austria 2004 - Subject: Regulation of Allergic Processes Recipients of the Award Bart Lambrecht Dendritic cells and the regulation of the allergic USD 50 000 Rotterdam, The Netherlands immune response Recipients of an Honourable Mention Omid Akbari The master regulators of allergic disease and asthma; dendritic Stanford, CA, USA cells, TReg & NKT cells Anthony Coyle IgE immunoglobulin, cytokines and costimulatory molecules: Cambridge, MA, USA novel insights into the pathogenesis of mucosal inflammation Khurana Hershey Regulation of allergic inflammation Cincinatti, OH, USA 2003 - Subject: Novel developments in the understanding of IgE associated diseases Recipients of the Award Gesine Hansen Immunoregulatory mechanisms in allergic asthma USD 50 000 Halle, Germany Recipients of an Honourable Mention Omid Akbari Mechanisms of tolerance that protect against the development of Stanford, CA, USA asthma Natalija Novak New players in the atopic game – the antigen-presenting dendritic Bonn, Germany cells 2002 - Subject: Determinants of Allergenicity Recipients of the Award Anna Pomés, Intrinsic properties of allergens and environUSD 50 000 Charlottesville, VA, USA mental exposure as determinants of allergenicity Recipients of an Honourable Mention Susanne Vrtala Genetically engineered allergen derivates for specific Vienna, Austria immunotherapy of type I allergy 2001 - Subject: Immunopathogenesis of Respiratory Diseases Recipients of the Award Mark Larché London, United Kingdom Direct activation of allergen specific T cells in USD 50 000 vivo: a novel system for investigating the immunopatho-genesis of allergic asthma Recipients of an Honourable Mention Nikolaos Papadopoulos, Mechanisms of rhinovirus-induced asthma exacerbations Athens, Greece Fellowships (USD 1 500) Athanasios Konstantinidis, Southampton, United Kingdom Paola Romagnani, Florence, Italy Daphne Tsitoura, Athens, Greece Guang Wong, Boston, MA, USA 2000 - Subject: Regulation of Cellular Mechanisms in Allergic Diseases Recipients of the Award Stephan C Bischoff Regulation of human mast cell, basophils and USD 30 000 Hannover, Germany eosinophils: implications for allergic diseases Christof Ebner Characterization of T-lymphocyte responses to USD 20 000 Vienna, Austria atopic allergens Recipients of an Honourable Mention Bart N Lambrecht The dendritic cell as a critical regulator of the cellular immune Rotterdam, The Netherlands response to inhaled allergen Anders Lindén, Gothenburg, Interleukin-17 and airway neutrophils in asthma Sweden Joachim Saloga, Mainz, Regulation of cellular mechanisms in allergic diseases and Germany their therapy: preeminent role of interleukin-10 and modulatory influence of superantigen exposure Fellowships (USD 1 250) Lisa Cameron, Montreal, Quebec, Canada Gilles Devouassoux, Grenoble, France Radhika Kajekar, Baltimore, USA Andrea Keane-Myers, Boston, MA, USA Stefan Kraft, Bonn, Germany Michael Lahn, Denver, Colorado, USA Bart Lambrecht, Rotterdam, The Netherlands Misato Miaymaso, Tokyo, Japan Susanna Olsson, Genova, Italy Holger Petering, Hannover, Germany 1999 - Subject:Regulation of Cellular Mechanisms in Allergic Diseases Recipients of the Award David Dombrowicz Allergy-associated FcR, an amplifier of IgE and IgG USD 25 000 Lille, France receptor-mediated anaphylaxis Federica Sallusto Th1 and Th2 traffic directed by chemokine receptors USD 25 000 Basel, Switzerland Recipients of an Honourable Mention Jörn Elsner Receptor interactions of human eosinophils in allergic inflammation Hannover, Germany Teruaki Kimura The mechanism of intracellular signal transduction through the high Tokyo, Japan affinity IgE receptor (FcRI) Fellowships (2 500) Mitchel Grayson, St. Louis, MO, USA Gurjit Khurana Hershey, Cincinatti, USA Orathai Jirapongsananuruk, Denver, CO, USA Chris Kepley, Albuquerque, NM, USA Teruaki Kimura, Tokyo, Japan Donna-Marie McCafferty, Calgary, Alberta, Canada Abdeilah Soussi Gounni, Montreal, Quebec, Canada Andreas Wollenberg, Munich, Germany 1998 - Subject: Genetic and molecular basis of allergic inflammation Recipients of the Award Santa Ono Molecular genetics of IgE-mediated inflammation USD 25 000 Boston, Mass, USA Marc Rothenberg Molecular and genetic characterization of eotaxin USD 25 000 Cincinatti, USA and related chemokines in allergic inflammation Recipients of an Honourable Mention Hans-Uwe Simon Molecular mechanisms of delayed eosinophil apoptosis in allergic Davos, Switzerland inflammation Fellowships (USD 2 500) David Dombrowicz, Lille, France Silvia Hanissian, Milan, Italy Christopher Kepley, Albuquerque, USA Joel Kline, Iowa City, USA James McDonnell, New York, USA Miriam Moffat, Oxford, United Kingdom Alistair Noble, London, United Kingdom John Penrose, Boston, USA Hans-Uwe Simon, Davos, Switzerland Cristiana Stellato, Baltimore, USA 1997 - Subject: Regulation of IgE synthesis and its inflammatory consequences Recipients of the Award Paul Rothman Regulation of IgE synthesis USD 50 000 New York, NY, USA Recipients of an Honourable Mention Michel Arock IgE-mediated activation of human epidermal keratinocyte: a new Paris, France target for therapy in skin allergic disease Bing Lam Leukotriene C4 synthase: an enzyme critical to IgE-mediated allergic Boston, MA, USA responses Fellowships (USD 2 500) Cezmi A Akdis, Davos, Switzerland Michel Arock, Paris, France Naveen Arora, Delhi, India Angela Haczku, Denver, CO, USA Eckard Hamelmann, Denver, CO, USA Bing K Lam, Boston, MA, USA Markus Neurath, Mainz, Germany Yoshimichi Okayama, Maebashi, Japan Konrad Pazdrak, Galveston, TX, USA Seif Shaheen, London, United Kingdom 1996 - Subject: Immunomodulation of allergic diseases Recipients of the Award Rudolf Valenta Recombinant allergens for diagnosis and therapy of USD 50 000 Vienna, Austria allergic diseases Recipients of an Honourable Mention Bruce Bochner Mechanisms responsible for preferential recruitment of human Baltimore, USA eosihophils and basophils during allergic inflammation Juha Punnonen IL-13 induces germline transcription and IgE synthesis by normal Palo Alto, USA and immature human B-cells: inhibition of IL-4- and IL-13-induced IgE production by an IL-4 mutan protein Fellowships (USD 2 500) Christof Ebner, Vienna, Austria Steve Georas, Baltimore Majed Hamaway, Bethesda, USA Gerard Hoyne, London, United Kingdom Sophie Laberge, Montreal, Canada Akio Mori, Tokyo, Japan Chad Oh, Torrance, CA, USA Juha Punnonen, Palo Alto, CA, USA Mimi Tang, Durham, NC, USA Ke Zhang, Los Angeles, CA, USA 1995 - Subject:Mechanisms of mediator release in allergic inflammation Recipients of the Award Hans C Oettgen Boston, USA Marc Benhamou Paris, France Mast cell degranulation and active systemic USD 15 000 anaphylaxis in IgE-deficient mice USD 10 000 Fc RI-dependent protein-tyrosine phosphorylation: a paradigm for the molecular basis of IgE-mediated cell activation in the allergic reaction Recipients of an Honourable Mention Piotr Kuna The role of chemokines in the mechanism of mediator Lodz, Poland release from human basophils in allergic inflammation Peter Willem G van der Linden, Pathogenesis of insect-sting anaphylaxis Haarlem, The Netherlands Fellowships (USD 2 500) Lars Olof Cardell, Malmö, Sweden Heli Hyry, Helsinki, Finland Sergejs Kuznetsovs, Riga, Latvia Joaquim Mullol, Barcelona, Spain Gunnar Nilsson, Uppsala, Sweden Lars Jelstrup Petersen, Copenhagen, Denmark Ying Sun, London, United Kingdom Neven Tudoric, Zagreb, Croatia Philipp Yu, Freiburg, Germany Eugini Zhiburt, St. Petersburg, Russia Marius Zolubas, Klaipeda, Lithuania 1994 - Subject: Environmental and genetic influences on allergic inflammation Recipients of the Award Thomas Bieber Munich, Germany David Lang Philadelphia, USA The high affinity receptor for IgE (Fc RI) on human dendritic antigen presenting cells: a novel connection between the immune system and the environment Asthma mortality and the urban environment USD 12 500 USD 12 500 Recipients of an Honourable Mention Fellowships (USD 3 000) Fellowship (USD 2 000) Michele Columbo, Naples, Italy Christopher Corrigan, London, United Kingdom Jay Portnoy, Kansas City, USA Paul Rothman, New York, NY, USA Andrew Bentley, Oxford, United Kingdom Moises Calderon-Zapata, London, United Kingdom Sigurdur Kristjánsson, Gothenburg, Sweden Jill Warner, Southampton, United Kingdom 1993 - Subject: Mediators of allergic inflammation Recipients of the Award Rafeul Alam Galveston, Texas, USA Massimo Triggiani Naples, Italy Cytokines modulating the function of the effector cells of allergic inflammation Analogs of platelet-activating factor produced by inflammatory cells: biochemistry and biological activities Recipients of an Honourable Mention Jonathan P Arm The role of leukotrienes in bronchial asthma London, United Kingdom Fellowships (USD 3 000) Johathan P Arm, London, United Kingdom Thomas Brunner, Bern, Switzerland Ratko Djukanovic, Southampton, United Kingdom USD 15 000 USD 5 000 Qutayba A Hamid, London, United Kingdom Douglas S Robinson, London, United Kingdom 1992 - Subject: Advances in the treatment of allergic diseases Recipients of the Award Shyam Mohapatra Diagnosis and therapy of IgE-mediated allergies with USD 10 000 Bad Lippspringe, Germany recombinant allergens: poa pratensis IX as a model Recipients of an Honourable Mention Chris Corrigan A novel therapeutic approach to asthma based on the London, United Kingdom inhibition of T-lymphocyte function Kent HayGlass Modulation of IL-4 and IFN synthesis in vivo via Winnipeg, Canada administration of chemically modified allergens Peter Howarth Airway inflammation in asthma: influence of and potential for Southampton, United Kingdom therapeutic intervention Fellowships 1991 - Subject: Regulation of IgE production Recipients of the Award Mike Kemeny London, United Kingdom Harald Renz Denver, Col, USA USD 12 500 The role of CD8+T cells results in the regulation of IgE USD 7 500 Characterization of the role of TCR V elements in the regulation of IgE production and the development of altered airways responsiveness Recipients of an Honourable Mention Hirokazu Okudaira Regulation of human spontaneous IgE synthesis in vitro and in vivo Tokyo, Japan Jörg C Prinz Regulatory role FcR2/CD23+T cells in the human IgE response Munich, Germany Beda M Stadler Human IgE Regulation: is there a unifying concept? Bern, Switzerland 1990 - Subject: Cellular communications in allergic asthma Recipients of the Award Tak Lee Cellular communications in allergic asthma USD 10 000 London, UK Judah Denburg Cellular and molecular basis of allergic airway USD 5 000 Hamilton, Ontario, CA inflammation Recipients of an Honourable Mention Sabina Mattoli Human bronchial epithelial cells exposed to isocyanates potentiate Milan, IT the activation and proliferation of T cells induced by antigen receptor triggering through the release of IL-1 and IL-6 Anthony J Frew Cellular infiltration and activation in allergen-induced late phase Stoke-On-Trent, UK reactions Gianni Marone Basophil and mast cell releasability in allergic disorders Naples, IT Fellowships 1989 - Subject: IgE-mediated allergy in childhood Recipients of the Award Patrick G Holt Subiaco, Western Australia The role of immunological tolerance mechanisms in USD 10 000 protection against allergic sensitization in the respiratory tract: contrasting effects of aeroallergen exposure in adult versus newborn animals Donata Vercelli A two-signal model for the induction of IgE USD 5 000 Boston, Massachusetts, US synthesis in humans Recipients of an Honourable Mention ????? Induction of human IgE and IgG synthesis by in vitro stimulation of blood mononuclear cells with purified recombinant human interleukin 4 Laboratories UNICET The role of IL-4, IFN- and IFN- in the regulation of IgE synthesis Dardilly, France* by peripheral blood lymphocytes of atopic and allergic children in vitro * Drs Francoise Rousset, Jérôme Pène, Isabelle Chrétien, Francine Vrière, Jan E de Vries 1988 - Subject: IgE in allergic inflammation Recipients of the Award Monique Capron-Dupont, Lille, France USD 15 000 Eosinophils and allergic inflammation: role of Fc RII in IgE-dependent mediator release Recipients of an Honourable Mention Sergio Bonini From IgE to allergic inflammation. An eye model Rome, Italy Judah Denburg In situ hemopoietic mechanisms underlying allergic tissue Hamilton, Ontario, Canada inflammation Philip Marsh IgE in allergic inflammation London, Great Britain Dale T Umetsu Induction of IgE synthesis by human T cell clones Palo Alto, California, USA Fellowships 1987 - Subject: IgE-mediated allergic reactions Recipients of the Award Martin D Chapman, Allergen specific monoclonal antibodies: new tools USD 10 000 Charlottesville, USA for the management of allergic disease Carla Bruijnzeel-Koomen A role for IgE in patch test reactions to inhalant USD 5 000 Utrecht, The Netherlands allergens in patients with atopic dermatitis Recipients of an Honourable Mention Walter Dorsch IgE and common allergic diseases Munich, West Germany Spephen T Holgate The contribution of mast cell mediators to acute allergic reactions Southampton, Great Britain in human skin and airways Sergio Romagnani Development and application of in vitro models for the study of Florence, Italy human IgE synthesis
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