Download PhD, MD. Marek Drab Academic career: Professional Experience:

PhD, MD. Marek Drab
Born: May 26, 1960, Cracow, Poland,
Major Specialist in Research Instrumentation USI,
Unit of Nanostructural Biointeractions Laboratory of Medical
Microbiology, Ludwik Hirszfeld Institute of Immunology and Experimental
Therapy of the Polish Academy of Sciences, Wroclaw, Poland,
[email protected]
Academic career:
2014 - Habilitation, Medical Sciences, Cell Biology, Wroclaw Medical University
1992 - Specialization in Internal Medicine, II Degree
1991 - Ph.D., Silesian School of Medicine, Katowice, Poland,
1988 - Specialization in Internal Medicine, I degree
1985 - Physician of Human Medicine, Silesian School of Medicine, Katowice, Poland
1979-1985 - M.D., Silesian School of Medicine, Katowice, Poland
Professional Experience:
Scientific Metrics: Hirsch Index = 16, citations = 1902 (without self-citations), publications
number = 23, impact factor = 132, Research experience record: 17 years of uninterrupted
postdoctoral scientific experience in Europe and USA.
Current position: October 2010 until now: Major Research Specialist in Advanced Imaging Systems
and Cell Biology at the Institute of Immunology and Experimental Therapy, Polish Academy of
Sciences, Wroclaw, Poland, with HP Freezing Cryo FIB-SEM technology
Centers of scientific excellence in Europe: 2008- 2010 Senior Researcher, EU FP7 Program
PEOPLE Marie-Curie for advanced researchers, INSERM Unit U1002, Necker Faculty of
Medicine,
University
of
Rene
Descartes,
Paris,
France
(webpage:
http://www.necker.fr/u1002/html/people.html) and Pasteur Institute Paris, France
2004-2008 Team Leader in Dept. of Molecular Biology, Max-Planck-Institute of Infection Biology,
Berlin, Germany, Since 1993 to 2004 Postdoctoral Fellow at the centers of scientific excellence in
Europe and USA, i.e. Max-Planck-Institute of Cell Biology and Genetics, Dresden, Dept. of
Pharmacology, Medical Faculty, Technical University of Dresden, Max-Delbrueck Center for
Molecular Medicine, Berlin, Unit of Embryonic Stem Cell Research, IPK, Gatersleben, Germany,
Franz-Volhard Clinic, Free University, Berlin, Dept. of Pharmacology, University of Heidelberg, all
in Germany.
Field of expertise: analysis of plasma membrane lipid assemblies (lipid rafts and caveolae), cell
cytoskeleton, cell-to-cell junctions, ion channels, and calcium and nitric oxide signaling pathways.
Biological objects of my study range from technology of the stem cells, including generating of
gene knockout, in vitro differentiating tissues from totipotent and pluripotent embryonic stem cell
primary cells and cell lines, whole organisms, cross tree of evolution - from mice, through sharks, to
humans, and up to pathogenic bacteria like Neisseriae and Chlamydiae.
Recent or Important Publications:
Mammalian Host-Versus-Phage immune response determines phage fate in vivo. Hodyra-Stefaniak
K, Miernikiewicz P, Drapała J, Drab M, Jończyk-Matysiak E, Lecion D, Kaźmierczak Z, Beta W,
Majewska J, Harhala M, Bubak B, Kłopot A, Górski A, Dąbrowska K. Scientific Reports 2015, IF
5.578,
Endothelial Caveolin-1 regulates the radiation response of epithelial prostate tumors. Klein D,
Schmitz T, Verhelst V, Panic A, Schenck M, Reis H, Drab M, Sak A, Herskind C, Maier P,
Jendrossek V. Oncogenesis. 2015, IF 3.952
Caveolin-1 opens endothelial cell junctions by targeting catenins. Kronstein R, Seebach J,
Grossklaus S, Minten C, Engelhardt B, Drab M, Liebner S, Arsenijevic Y, Taha AA, Afanasieva T,
Schnittler HJ. Cardiovasc Res. 2012, IF 6.064
From totipotent embryonic stem cells to spontaneously contracting smooth muscle cells: a retinoic
acid and db-cAMP in vitro differentiation model. Drab M, Haller H, Bychkov R, Erdmann B,
Lindschau C, Haase H, Morano I, Luft FC, Wobus AM. FASEB J. 1997, IF: 14.629 and the Cover
Page
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice.
Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F,
Luft FC, Schedl A, Haller H, Kurzchalia TV. Science. 2001, IF 23.329 and the dedicated
Perspective article in Science by R. Parton
Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of
blood vessels. Yu J, Bergaya S, Murata T, Alp IF, Bauer MP, Lin MI, Drab M, Kurzchalia TV, Stan
RV, Sessa WC. J Clin Invest. 2006 IF: 15.754 and the dedicated Commentary article in J Clin
Invest. by Lisanti and Frank
See also immediate comments on dr. M. Drab work in following journals: Science, 293, 2404-2405,
2001, Cell, 106, 403-411, 2001, Nature, 415, 8-10, 2002, Nature Mol Cell Biology, 2, 788, 2001, J
Cell Biol 154, 904, 2001).
Patents:
International patent on the method of totipotent mouse embryonic stem cell in vitro differentiation
into functional smooth muscle.