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PERSONAL INFORMATION
SOULA Anaïs, French, born 12 March 1990
[email protected]
EDUCATION
2011-2013: Master in Cellular Biology, Physiology, Pathology (Bordeaux University, France)
2009-2011: Bachelor in Biology of Organisms (Anglet University, France)
2008-2009: Prestigious Preparatory Classes of the “Grandes Écoles” in Biology, Chemistry, Physics (Pau, France)
2008: Scientific Baccalauréat (Bayonne, France)
PRICES AND DISTINCTIONS
2016: 1-year PhD fellowship from the Foundation for Medical Research (FRM)
2016: Keystone Symposia scholarship (from National Cancer Institut) - Exosomes/Microvesicles : Novel
Mechanism of Cell-Cell Communication
2013: 3-year PhD fellowship from the French National Research Ministry - ranked 14/83
2013: Major of the Master in Cellular Biology, Physiology, Pathology in Bordeaux University - ranked 1/30
2011: Top 5% of the Bachelor in Biology of Organisms in Anglet University, France - ranked 2/32
RESEARCH EXPERIENCE
since 2013:
2013:
2012:
2011:
PhD student under the supervision of Dr A. Favereaux at the Interdisciplinary Institute for
Neuroscience, Bordeaux University. Exosomal RNA shuttling: A novel type of communication
within the nervous system.
Master internship (6 months) with Dr A. Favereaux at the Interdisciplinary Institute for
Neuroscience, Bordeaux University. A new way of interneuronal communication: the exchange of
exosomal miRNAs.
Master internship (2 months) with Dr J.M. Pasquet at Bordeaux University. Validation of a model
of leucemic stem cells.
Bachelor internship (2 months) with C. Staedel at Bordeaux University. Study of the miRNA
clusters 200 and 371-372-373 and their effects on the pathogenic regulation of Helicobacter pylori
bacteria.
PUBLICATION
• miR-92a regulates expression of synaptic GluA1-containing AMPA receptors during homeostatic scaling;
Letellier M, Elramah S, Mondin M, Soula A, Penn A, Choquet D, Landry M, Thoumine O, Favereaux A, Nature
Neurosciences, 2014 Aug;17(8):1040-2
SCIENTIFIC EXPERTISE
• Intercellular communication through exosome-like vesicles / microvesicles
• Communication between neurons, astrocytes and microglia
• Post-transcriptional regulation by miRNAs
TECHNICAL SKILLS
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Cell biology: Rat hippocampus and cortex primary culture, exosomal purification methods, cell line culture
Molecular biology: cloning, RNA extraction, PCR, RT-qPCR, Luciferase assay, Next Generation Sequencing
Biochemistry: Western-blot, ISH, ICC
Microscopy: Epi-fluorescence microscopy, confocal microscopy
ORAL COMMUNICATIONS
• 2016: Short talk at the Keystone Symposia : Exosomes/Microvesicles : Novel Mechanism of Cell-Cell
Communication
• 2016: Symposium of young scientists, University of Bordeaux, France
• 2016: Meeting of Interdisciplinary Institute for Neuroscience, Bordeaux, France
POSTER PRESENTATIONS
• August 2016: Meeting of Gordon Research Conferences: Extracellular vesicles: Biological effects and
therapeutics potential, at Sunday River, USA. Role of exosomal RNAs in the context of neuronal plasticity.
SOULA A, Petrel M, Lefeuvre Y, Benquet S, Calas A, Landry M, Tremble A, Favereaux A
• June 2016 : Meeting of Keystone Symposia Exosomes/Microvesicles : Novel mechanism of Cell-Cell
Communication in Keystone, USA. An innovative cell-specific method for purifying exosomes from the nervous
system. SOULA A, Benquet S, Landry M, Favereaux A
• June 2016 : Meeting of Keystone Symposia Exosomes/Microvesicles : Novel mechanism of Cell-Cell
Communication in Keystone, USA. Involvement of exosomal miRNAs in the mechanisms of neuronal plasticity.
SOULA A, Petrel M, Lefeuvre Y, Trembleau A, Calas A, Landry M, Favereaux A
• May 2015: Meeting of the French Neuroscience Society in Montpellier, France. Exosomal vesicles released by
neurons contain miRNAs that could modulate gene expression of neighboring cells. SOULA A, M Petrel, PA
Guerin, P Robillard, Y Le Feuvre, A Calas, E Gontier, M Landry, A Favereaux
•August 2014: Cold Spring Harbor Meeting on Regulatory and Non-coding RNAs. Exosomal vesicles released by
neurons contain miRNAs that could modulate gene expression of neighboring cells, SOULA A, M Petrel, PA
Guerin, P Robillard, Y Le Feuvre, A Calas, E Gontier, M Landry, A Favereaux
• May 2014: Symposium of the Bordeaux RNA Club. Exosomal vesicles released by neurons contain miRNAs that
could modulate gene expression of neighboring cells, SOULA A, M Petrel, PA Guerin, P Robillard, A Calas, E
Gontier, M Landry, A Favereaux
• Novembre 2013: Society for Neuroscience Meeting in San Diego, USA. Exosomal vesicles released by neurons
contain miRNAs that could modulate gene expression of neighboring cells, SOULA A, P Robillard, S Elramah, A
Calas, M Petrel, E Gontier, M Landry, A Favereaux
TRAINING AND COURSES
2016: Basics in Next Generation Sequencing - RNA-seq
2016: Basics in Finances and Management at IAE Bordeaux
2015: Confocal imaging course, Bordeaux Imaging Center
2014-2015: Teaching assistant in the undergraduate program of Cellular Biology in Bordeaux University
2013-2014: “Teaching by teaching”, pedagogic course - Bordeaux University
EXTRACURRICULAR ACTIVITIES
2014-2016: Secretary of 2D2B - Association of Biology PhD students and PhDs of Bordeaux
- Organization of monthly neuroscientific seminars for PhD students
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Organization of a career development session with French Society of Neurosciences (SFN)
Organization of the Doctoral School day of Bordeaux University
Organization of Pint of Science in Bordeaux, themes “Human body”, 2016 and “Marine biology”, 2015
Preparation of Master students for the entrance exam of the Doctoral School
2013-2014: Active member of the TBM’docs association
- Organizer of events for PhD students concerning a career outside science
- Organization of “the day of young researchers” at Bordeaux University