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Southern Medical Association Central Aortic Systolic Pressure in Postural Orthostatic Tachycardia Syndrome (POTS) P-4 The following abstract will be presented at the Southern Medical Association Annual Scientific Assembly, October 29-31, 2015, in Destin, Florida. Author and Co-Authors Chandralekha Ashangari, MBBS; Neelesh Gupta; Henykumar Dilipkumar Patel, MBBS; Amer Suleman, MD, FHRS, FSCAI; Department of Cardiology – The Hearbeat Clinic, Dallas, TX. Upon completion of the lecture, learners should be better prepared to: Objectives Abstract Disclosure 1) Know the mean Central Aortic systolic pressure in POTS patients. 2) Determine the systolic blood pressure, diastolic blood pressure, pulse rate, mean arterial pressure in POTS patients. Background: POTS is a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and symptoms like fatigue, headaches, lightheadedness, heart palpitations, exercise intolerance, nausea, diminished concentration, tremulousness (shaking), syncope (fainting), coldness or pain in the extremities, chest pain and shortness of breath upon standing. We had previously reported a paper demonstrating that POTS patients have lesser dimensions and high blood flow velocity in Aorta. Central Aortic Systolic Pressure (CASP) is the blood pressure at the root of the aorta or the largest artery in the body, as the blood is being pumped out of the heart. CASP has been shown to be an important factor in the relation to strokes and cardiovascular events, more so than the brachial pressure or the pressure at the arm commonly. The aim of this study is to determine the Central Aortic Systolic Pressure, Systolic Blood pressure, Diastolic blood pressure, Pulse rate, Mean arterial pressure in POTS patient. Methods: 56 Pots Patients from our clinic has CASP measurement performed. A device equipped with a wrist sensor module which is to be worn on the patient's wrist for blood pressure measurement. The sensor module is designed based on the concept of the BPro device which looks similar to a watch-like device and can be worn easily on the radial artery for measuring blood pressure noninvasively. The sensor's position is maintained by applying a consistent tension on the artery. Results: Out of 56 patients, 98% were females (n=55 age 30.58±10.80) and 2% were male (n=1,age 29).Our findings in mean ± standard deviation, Mean Arterial Pressure 92.42±9.69, Central Aortic Systolic Pressure (CASP) 110.17±11.63,SBP 120.44±11.29,DBP 81.31±9.34,Pulse Rate 83.08±11.96. Conclusion: CASP were normal in POTS Patients. Chandralekha Ashangari, MBBS – No Relevant Financial Relationships to Disclose Neelesh Gupta – No Relevant Financial Relationships to Disclose Henykumar Dilipkumar Patel, MBBS – No Relevant Financial Relationships to Disclose Amer Suleman, MD, FHRS, FSCAI – No Relevant Financial Relationships to Disclose