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Duke at ACC 2015 Duke at ACC 2015 March 14–16, 2015 San Diego, CA Duke at ACC 2015 Saturday, March 14 8:00–9:30 am Diabetes: New Concepts and TACTful Debates Daniel Mark, co-chair 8:15–8:25 am Challenges and Opportunities in ACS Is There Any Benefit to the Radial Approach in Women With ACS? Sunil Rao 8:45–8:55 am Challenges and Opportunities in ACS Is the Benefit Risk for Antithrombotic Therapy Altered in Women? Tracy Wang 9:05–9:20 am Opening Showcase and the Joint ACC/JACC Late-Breaking Clinical Trials A Randomized Comparison of Anatomic versus Functional Diagnostic Testing Strategies in Symptomatic Patients with Suspected Coronary Artery Disease: Results from the PROMISE Trial (PROspective Multicenter Imaging Study for Evaluation of chest pain) Pamela Douglas, Udo Hoffmann, Manesh Patel, Daniel Mark, Lawton Cooper, Kerry Lee 10:00–10:45 am Poster Presentations Race and Sex Differences in the QRS Interval Among Patients with Left Ventricular Systolic Dysfunction Tiffany Randolph*, Samuel Broderick, Linda Shaw, Robert Mentz, Karen Chiswell, Francis Gilliam, Kevin Thomas Room 33C Room 20A Room 20A Hall H (Main Tent) Poster Hall B1 The Association of Medicare Part D Enrollment with Outcomes After Acute Myocardial Infarction: An Analysis of Linked ACTION Registry-GWTG and Medicare Data Abhinav Goyal, James de Lemos, Andrew Peng, Laine Thomas, Ezra Amsterdam, Jason Hockenberry, Eric Peterson, Tracy Wang Temporal Trends in Care and Outcomes of Patients Receiving Fibrinolytic Therapy Compared to Primary Percutaneous Coronary Intervention in the Get With The Guidelines Coronary Artery Disease (GWTG-CAD) Registry Ravi S. Hira, Deepak Bhatt, Gregg Fonarow, Paul Heidenreich, Christine Ju, Salim Virani, Adrian Hernandez, Lee Schwamm, Zubin Eapen, Michelle Albert, Eric Peterson, Hani Jneid Temporal Trends in and Factors Associated with Single Versus Dual Coil Implantable Cardioverter-Defibrillator Leads: Data from the NCDR ICD Registry Sean Pokorney*, Craig Parzynski, James Daubert, Donald Hegland, Paul Varosy, Jeptha Curtis, Sana Al-Khatib Early Improvement in Flow (Left Ventricular Stroke Volume Index) After Transcatheter Aortic Valve Replacement Is Associated with Improved Survival in Low-Flow Aortic Stenosis Venkatesh Anjan, Howard Herrmann, Philippe Pibarot, William Stewart, Samir Kapadia, Murat Tuzcu, Vasilis Babaliaros, Vinod Thourani, Wilson Szeto, Joseph Bavaria, Susheel Kodali, Rebecca Hahn, Mathew Williams, Craig Miller, Pamela Douglas, Martin Leon Transcatheter Aortic Valve Replacement Results in Significant Reverse Remodeling in Patients with Left Ventricular Dilation: A Report from the PARTNER I Trial Melissa Daubert, Philippe Pibarot, Rebecca Hahn, Neil Weissman, William Stewart, Justina Wu, Sammy Elmariah, Brian Lindman, Murat Tuzcu, Rakesh Suri, Ke Xu, Martin Leon, Pamela Douglas Duke speakers and authors are in bold italics. *DCRI Fellows 2 Duke at ACC 2015 Duke at ACC 2015 Saturday, March 14 Poster Presentations The Association of Left Ventricular Ejection Fraction with 1-Year Mortality After Myocardial Infarction: Findings from the ACTION Registry-GWTG Medicare Linked Database Nadia Sutton, Shuang Li, Tracy Wang, James de Lemos, Jonathan Enriquez, Rashmee Shah, Laine Thomas, Gregg Fonarow Seasonal, Regional, and Circadian Variations of Acute Myocardial Infarction: Findings from the Get With The Guidelines- Coronary Artery Disease (GWTG-CAD) Program Vijaiganesh Nagarajan, Gregg Fonarow, Christine Ju, Michael Pencina, Warren Laskey, Thomas Maddox, Deepak Bhatt Does Baseline Global Longitudinal Strain Predict Mortality in High Risk Patients with Aortic Stenosis and Left Ventricular Dysfunction? Amit Vora*, Fawaz Alenezi, Allison Dunning, Phillip Schulte, Svati Shah, Joseph Kisslo, John Harrison, Eric Velazquez, Zainab Samad GlycA, a Novel Biomarker of Systemic Inflammation, Improves Cardiovascular Risk Prediction in a High-Risk Coronary Catheterization Cohort Robert McGarrah, Damian Craig, Carol Haynes, Elaine Dowdy, Svati Shah, William Kraus Risk Scores and Biomarkers for the Prediction of 1-Year Outcome After Transcatheter Aortic Valve Replacement Jan-Malte Sinning, Kai Wollert, Alexander Sedaghat, Christian Widera, Marie-Caroline Rademacher, Claire Descoups, Christoph Hammerstingl, Marcel Weber, Anja Stundl, Alexander Ghanem, Julian Widder, Mariuca Vasa-Nicotera, Fritz Mellert, Wolfgang Schiller, Johann Bauersachs, Berndt Zur, Stefan Holdenrieder, Armin Welz, Eberhard Grube, Michael Pencina, Georg Nickenig, Nikos Werner, Tibor Kempf Baseline LDL-C and Clinical Outcomes with Addition of Ezetimibe to Statin in 18,144 Patients Post ACS Robert Giugliano, Christopher Cannon, Michael Blazing, Jennifer White, Sabina Murphy, Andrew Tershakovec, Thomas Musliner, Robert Califf, Eugene Braunwald Initial Results from the CASCADE-FH Registry: CAscade SCreening for Awareness and Detection of Familial Hypercholesterolemia Emily O’Brien, Emil DeGoma, Patrick Moriarty, MacRae Linton, Michael Shapiro, Bart Duell, Christie Ballantyne, William Neal, Zahid Ahmad, Danielle Duffy, Lisa Hudgins, Linda Hemphill, James Underberg, Karol Watson, Samuel Gidding, Seth Baum, Kristen Dilzell, Joyce Ross, David Pickhardt, Iris Kindt, Daniel Rader, Katherine Wilemon, Matthew Roe, Joshua Knowles 10:30–10:40 am Moderated Poster Theater Poster Hall B1 Moderated Poster Sessions The First-Ever Pediatric Appropriate Use Criteria Implementation Project: A Large Multicenter Quality Initiative Ritu Sachdeva, Wyman Lai, Joseph Allen, Oscar Benavidez, Robert Campbell, Benjamin Eidem, Lara Gold, Michael Kelleman, Leo Lopez, Courtney E. McCracken, Kenan Stern, Rory Weiner, Elizabeth Welch, Pamela Douglas Risk Stratification for Cardiovascular Events in the IMPROVE-IT Trial Erin Ann Bohula May, Jennifer White, Michael Blazing, Robert Giugliano, Thomas Musliner, Andrew Tershakovec, Amy McCagg, Deepak Bhatt, Christopher Cannon, Robert Califf, Eugene Braunwald Metabolomic Profiling Identifies Biomarkers Predicting Adverse Outcomes in Patients with Heart Failure with Preserved Ejection Fraction Jacob Kelly*, Wynn Hunter, Damian Craig, Carol Haynes, Robert McGarrah, Eric Velazquez, Michael Felker, Adrian Hernandez, Olga Ilkayeva, Robert Stevens, James Bain, Michael Muehlbauer, Christopher Newgard, William Kraus, Svati Shah 3 Duke at ACC 2015 Saturday, March 14 11:00–11:10 am Moderated Poster Theater Poster Hall B1 Moderated Poster Sessions Association of Disease-Specific Health Status with Long-Term Mortality after Transcatheter Aortic Valve Replacement Suzanne Arnold, John Spertus, Sreekanth Vemulapalli, Dadi (David) Dai, Sean O’Brien, Suzanne Baron, Ajay Kirtane, Michael Mack, Philip Green, Matthew Reynolds, John Rumsfeld, David Cohen Metabolomic Profiling in Heart Failure Identifies Biomarkers of Mitochondrial Function in Preserved versus Reduced Ejection Fraction Wynn Hunter, Jacob Kelly*, Damian Craig, Carol Haynes, Robert McGarrah, Eric Velazquez, Michael Felker, Adrian Hernandez, Olga Ilkayeva, Robert Stevens, James Bain, Michael Muehlbauer, Christopher Newgard, William Kraus, Svati Shah 11:15–11:25 am Moderated Poster Theater Poster Hall B1 Moderated Poster Sessions Endovascular Recanalization of Superficial Femoral Artery Chronic Total Occlusions: A Multi-Disciplinary, Single Center Experience Aparna Swaminathan, Yuliya Lokhnygina, David Kopin, Michael Miller, Mitchell Cox, James Mills, Lawrence Crawford, Manesh Patel, William Jones Plasma Endothelin-1 Independently Predicts 180-Day Mortality in Acute Heart Failure: An ASCEND-HF Sub-Study Antonio Perez, Justin Grodin, Adrian Hernandez, Javed Butler, Marco Metra, Michael Felker, Adriaan Voors, John McMurray, Paul Armstrong, Robert Califf, Randall Starling, Christopher O’Connor, Wai Hong Tang 12:15–12:25 pm Critical Care Cardiology Intensive Welcome & Introduction Kristin Newby 12:15–6:00 pm Practice Management & Leadership Intensive and James T. Dove Lecture Pamela Douglas, program co-chair 12:15–6:00 pm Critical Care Cardiology Intensive Kristin Newby, program co-chair 12:45–1:00 pm End Organ Function in the Patient With Heart Failure Hepatic Function Adrian Hernandez 1:00–1:15 pm Team Management in Advanced Heart Failure, Cardiac Transplantation and VADs: Who Makes the Call? The Complex Patient: VAD, Transplant, VAD Exchange, or Hospice? Joseph Rogers 2:00–2:20 pm Critical Care Cardiology Intensive Choosing Acute Mechanical Circulatory Support Magnus Ohman 2:00–3:30 pm Current Dilemmas and Controversies: How Should We Be Choosing Which Patients to Receive PCI and Which to Stick with Medical Therapy Manesh Patel, panelist Room 7B Room 10 Room 7B Room 6E Room 6C Room 7B Room 6A 4 Duke at ACC 2015 Duke at ACC 2015 Saturday, March 14 2:00–3:30 pm DAPT in 2015: State of the Art Sunil Rao, co-chair 2:00–2:09 pm DAPT in 2015: State of the Art Stent Thrombosis versus Bleeding Risk with DAPT: A Critical Appraisal Sunil Rao 2:15–2:30 pm What Is the Best Way to Measure Congestion in the Patient With Heart Failure? Natriuretic Peptides Michael Felker 3:00–3:15 pm Navigating Heart Failure Care Transitions and Preventing Readmissions How Post Hospital Follow-up Impacts Readmission Adrian Hernandez 3:22–3:30 pm Current Dilemmas and Controversies How do Technological Developments and Clinical Studies Shape the Formulation of Guidelines and Appropriate Use Documents Manesh Patel 3:30–4:30 pm Fit Forum Clinical Research Eric Peterson 3:30–4:30 pm Fit Forum Imaging Pamela Douglas, Raymond Kim 3:30–4:30 pm Fit Forum Education Thomas Bashore 3:30–4:30 pm Fit Forum Geriatric Karen Alexander 3:30–4:30 pm Poster Presentations Selection of Prasugrel versus Clopidogrel Among Myocardial Infarction Patients with High versus Low Predicted Mortality and Bleeding Risks: Insights from TRANSLATE-ACS Amit Vora*, Eric Peterson, Lisa McCoy, Mark Effron, Kevin Anstrom, Douglas Faries, Marjorie Zettler, Gregg Fonarow, Brian Baker, Gregg Stone, Tracy Wang Room 6D Room 6D Room 6E Room 6C Room 6A ACC Bistro ACC Bistro ACC Bistro ACC Bistro Poster Hall B1 The Myth of the Stable INR Patient: Results from ORBIT-AF Sean Pokorney*, DaJuanicia Simon, Laine Thomas, Gregg Fonarow, Peter Kowey, Paul Chang, Daniel Singer, Jack Ansell, Rosalia Blanco, Bernard Gersh, Kenneth Mahaffey, Elaine Hylek, Alan Go, Jonathan Piccini, Eric Peterson 5 Duke at ACC 2015 Saturday, March 14 3:30–4:30 pm Poster Hall B1 Poster Presentations National Patterns in Intensity of Outpatient Care for Apparent Treatment Resistant Hypertension Sreekanth Vemulapalli, Luqin Deng, Manesh Patel, Meredith Kilgore, Lesley Curtis, Marguerite Irvin, Laura Svetkey, Daichi Shimbo, David Calhoun, Paul Muntner Statins and Exercise Training Response in Heart Failure Patients: Insights from the HF-ACTION Trial Jacob Kelly*, Robert Mentz, Phillip Schulte, Allison Dunning, Mona Fiuzat, Steven Keteyian, Jerome Fleg, Eric Leifer, Ileana Pina, Lawton Cooper, Dalane Kitzman, William Kraus, David Whellan, Christopher O’Connor Evaluating Change of Systolic Function after Revascularization in Patients with Multi Vessel Coronary Artery Disease, Severely Reduced Left Ventricular Systolic Function and No Scar on CMR Imaging Alexander Ivanov, James Yossef, Ambreen Mohamed, Joshua Socolow, Iossif Gulkarov, Berhane Worku, Anthony Tortolani, Pairoj Chattranukulchai, Terrence Sacchi, Robert Biederman, John Grizzard, Mohamad Ghosn, Igor Klem, John Heitner Tooth Loss Is Independently Associated with Adverse Outcome but Not Myocardial Infarction in Patients with Chronic Coronary Heart Disease Ola Vedin, Emil Hagstrom, Andrzej Budaj, Stephan Denchev, Robert Harrington, Wolfgang Koenig, Joseph Soffer, Piyamitr Sritara, Amanda Stebbins, Ralph Stewart, Henk Swart, Margus Viigimaa, Dragos Vinereanu, Lars Wallentin, Harvey White, Claes Held Tricuspid Regurgitation Improves but Right Ventricular Function Does Not After Repair of Pre-Tricuspid Valve Left-to-Right Shunts Asad Shah, Alexis Antunez, Andrew Lodge Serum Bicarbonate in Acute Heart Failure: Relationship to Treatment Strategies and Clinical Outcomes Lauren Cooper*, Robert Mentz, Dianne Gallup, Anuradha (Anu) Lala-Trindade, Justin Vader, Omar AbouEzzeddine, Javed Butler, Bradley Bart, Horng Chen, Margaret Redfield, Lynne Stevenson, Christopher O’Connor, Kevin Anstrom, Adrian Hernandez, Michael Felker Acute Kidney Injury with Transcatheter Aortic Valve Replacement in the U.S.: Can We Reduce the Risk? Charles Brooks, Jennie Ma, Sandra Burks, Rachel Simon, Amanda Stebbins, Gorav Ailawadi, Michael Ragosta, Scott Lim, John Kern, Irving Kron A Phase 1 Study of the Safety and Pharmacokinetics of the Intravenous Nitroxyl Prodrug, CXL-1427 Doug Cowart, Robert Venuti, Jeffrey Guptill, Robert Noveck, Shiyin Foo 4:45–6:00 pm Practice Management & Leadership Intensive and James T. Dove Lecture Pamela Douglas, co-chair 4:45–6:00 pm Critical Care Cardiology Intensive James Jollis, panelist 4:45–6:00 pm A Clinical Dilemma: Acute Coronary Syndromes in the Perioperative Patient Tracy Wang, panelist 5:27–5:35 pm Optimal Primary PCI (PPCI) for STEMI Current State-of-the-Art Is there a Role for Periprocedural GP IIb/IIIa Inhibition in 2015? What Agent and Route of Administration? (abciximab vs. tirofiban vs. eptifibatide) James Tcheng Room 10 Room 7B Room 6F Room 6D 6 Duke at ACC 2015 Duke at ACC 2015 Saturday, March 14 5:30–5:45 pm Lessons From the Luminaries of Women in Cardiology Lessons From a Legend in Clinical Research Pamela Douglas 5:27–5:35 pm Optimal Primary PCI (PPCI) for STEMI Current State-of-the-Art Inhibition in 2015? What Agent and Route of Administration? (abciximab vs. tirofiban vs. eptifibatide) James Tcheng Room 4 Room 6D Sunday, March 15 8:00–8:20 am Big Data: Future of Cardiovascular Medicine IV ACC Talk: So Just What is Big Data? James Tcheng 8:00–9:15 am Late-Breaking Clinical Trials Eric Peterson, co-chair 8:00–9:30 am Big Data: Future of Cardiovascular Medicine IV James Tcheng, co-chair 8:00–9:30 am Highlighted Original Research: Congenital Heart Disease and the Year in Review Robert Jaquiss, co-chair 8:00–9:30 am FIT Forum: Stump the Professor Thomas Bashore, judge 8:15–8:27 am Highlighted Original Research: TCT@ACC Temporal Trends in Admission Status and Predicted Mortality Among Patients Undergoing Non-Acute Percutaneous Coronary Intervention: A Report from the National Cardiovascular Data Registry Amit Vora*, Dadi (David) Dai, Hitinder Gurm, Amit Amin, John Messenger, Ehtisham Mahmud, Laura Mauri, Tracy Wang, Matthew Roe, Jeptha Curtis, Eric Peterson, Sunil Rao 8:30–8:40 am Late-Breaking Clinical Trials A Randomized, Open-Label, Multi-Center, Active-Controlled, Parallel Group Study To Determine the Efficacy and Safety of the REG1 Anticoagulation System Compared to Bivalirudin in Patients Undergoing Percutaneous Coronary Intervention Roxana Mehran, A. Lincoff, Steven Zelenkofske, Paul W. Armstrong, Philippe Steg, Christoph Bode, Thomas Povsic, John Alexander 8:30–8:45 am Breakthroughs and Controversies in Imaging: Non-Invasive Imaging Viability: No Need to Image, No Need to Operate Eric Velazquez Room 20D Hall H (Main Tent) Room 20D Room 31C Room 9 Room 8 Hall H (Main Tent) Room 2 7 Duke at ACC 2015 Sunday, March 15 8:45–8:57 am Highlighted Original Research: Congenital Heart Disease and the Year in Review Trends in Right Ventricular Dysfunction and Tricuspid Regurgitation After Single Ventricle Palliation of Hypoplastic Left Heart Syndrome and Their Differential Impact on Survival Travis Wilder, Eugene Blackstone, Jeevanantham Rajeswaran, Christopher Caldarone, Peter Gruber, Bahaaldin Alsoufi, Robert Jaquiss, Christo Tchervenkov, James Jaggers, Ming-Sing Si, Christopher Mascio, Christian Pizarro, David Overman, Edward Hickey 8:50–9:10 am Big Data: Future of Cardiovascular Medicine IV The BASELINE Study – Thinking Big (Data) Kristin Newby 9:00–9:10 am Late-Breaking Clinical Trials Economic Comparison of Anatomic Versus Functional Diagnostic Testing Strategies in Symptomatic Patients with Suspected CAD: Results from the PROspective Multicenter Imaging Study for Evaluation of chest pain (PROMISE) Trial Daniel Mark, Kevin Anstrom, Patricia Cowper, Linda Davidson-Ray, Udo Hoffmann, Manesh Patel, Lawton Cooper, Kerry Lee, Pamela Douglas 9:00–9:12 am Fellows Bootcamp Basics and Coronary I: Case-Based Learning Quality Initiatives in the AUC Era Sunil Rao 9:10–9:30 am Big Data: Future of Cardiovascular Medicine IV Kristin Newby, panelist 9:15–9:27 am Highlighted Original Research: Heart Failure/Cardiomyopathies and the Year in Review Adrenergic Receptor Polymorphisms Interact with Beta-Blocker Dose Effect on Heart Failure Outcomes Especially in Black Race: Results from HF-ACTION DNA Substudy Kishan Parikh, Mona Fiuzat, Megan Neely, Tariq Ahmad, Michael Felker, Ileana Pina, Kirkwood Adams, Mark Donahue, William Kraus, David Whellan, Christopher O’Connor 9:45–9:55 am Moderated Poster Session Has Public Reporting of Readmissions Improved Care for Patients with Heart Failure? Adam DeVore*, Bradley Hammill, Zubin Eapen, Eric Peterson, Adrian Hernandez 9:45–10:30 am Poster Presentations One Size Does Not Fit All: Considering Different Statin Therapy Cutpoints by Age and Sex Ann Marie Navar-Boggan, Michael Pencina, Ralph D’Agostino, Eric Peterson, Allan Sniderman Room 31C Room 20D Hall H (Main Tent) Room 6F Room 20D Room 6C Moderated Poster Theater Poster Hall B1 Poster Hall B1 J-Shaped Relationship between Resting Heart Rate and Mortality in Patients with Permanent AF: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Benjamin Steinberg, Sunghee Kim, Laine Thomas, Gregg Fonarow, Bernard Gersh, Fredrik Holmqvist, Elaine Hylek, Peter Kowey, Kenneth Mahaffey, Gerald Naccarelli, James Reiffel, Paul Chang, Eric Peterson, Jonathan Piccini Outcomes in Patients with a Family History of Atrial Fibrillation: Findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation Anna Gundlund, Emil Loldrup Fosboel, Sunghee Kim, Gregg Fonarow, Bernard Gersh, Alan Go, Peter Kowey, Elaine Hylek, Kenneth Mahaffey, Paul Chang, Laine Thomas, Eric Peterson, Jonathan Piccini Reconsidering Appropriate Dofetilide Dosing in Women Sean Pokorney*, Debbie Yen, Kristen Campbell, Nancy Allen LaPointe, Sana Al-Khatib 8 Duke at ACC 2015 Duke at ACC 2015 Sunday, March 15 Poster Presentations The Prognostic Significance of Positive Electrocardiography Findings with Normal Exercise Echocardiography Joseph Sivak, Melissa Daubert, Stephanie Minter, Alicia Armour, Amanda Tinnemore, Ross Smith, Linda Benedict, Brian Coyne, Zainab Samad, Eric Velazquez Twelve-Year Follow-up of 213 Patients with Percutaneous Atrial Septal Defect Closure Guided by CMR imaging Wassim Shatila, Robert Aertker, Jonathan Kochav, Asvin Ganapathi, Andrew Lodge, Anna Lisa Crowley, John Vavalle, Todd Kiefer, Kevin Harrison Patterns of Adherence to Dual Antiplatelet Therapy in Patients with Coronary Artery Disease Undergoing Complex Percutaneous Coronary Intervention: Insights from the PARIS Registry Gennaro Giustino, Usman Baber, Jennifer Yu, Samantha Sartori, Cono Ariti, Stuart Pocock, Timothy Henry, David Cohen, David Moliterno, Mitchell Krucoff, Annapoorna Kini, Antonio Colombo, Alaide Chieffo, Roxana Mehran Outcomes Following Urgent or Emergent Coronary Artery Bypass Grafting in Patients with Cardiogenic Shock and an Unresponsive Pre-Operative Neurologic State Brian Gulack*, Xia He, Matthew Williams, Vinod Thourani, Jeffrey Jacobs, Matthew Brennan, Deepak Acharya 10:45–10:55 am Late-Breaking Clinical Trials III Five-Year Outcomes after Randomization to Transcatheter or Surgical Aortic Valve Replacement: Final Results of the PARTNER 1 Trial Michael Mack, Martin Leon, Craig Miller, Jeffrey Moses, Lars Svensson, Murat Tuzcu, John Webb, Pamela Douglas, William Anderson, Eugene Blackstone, Susheel Kodali, Raj Makkar, Gregory Fontana, Samir Kapadia, Joseph Bavaria, Rebecca Hahn, Vinod Thourani, Vasilis Babaliaros, Augusto Pichard, Howard Herrmann, David Brown, Mathew Williams, Jodi Akin, Craig Smith 10:45 am–12:15 pm Difficult Decisions in Older Adults Considering CV Therapies Joseph Rogers, panelist 11:00–11:10 am Late-Breaking Clinical Trials III A Randomized Comparison of Self-expanding Transcatheter and Surgical Aortic Valve Replacement in Patients with Severe Aortic Stenosis Deemed at Increased Risk for Surgery 2-Year Outcomes Michael Reardon, David Adams, Neal Kleiman, Steven Yakubov, Joseph Coselli, Michael Deeb, Thomas Gleason, Maurice Buchbinder, Blase Carabello, James Hermiller, Patrick Serruys, Stanley Chetcuti, John Heiser, William Mehri, George Zorn, Peter Tadros, Newell Robinson, George Petrossian, Chad Hughes, Kevin Harrison, John Conte, Jae Oh, Jeffrey Popma 11:10–11:30 am Joint Symposium of the Chinese Society of Cardiology and the American College of Cardiology Christopher Granger, moderator and panelist 11:15–11:25 am Prosthetic Valve Complications: Challenges in Diagnosis and Management Prosthetic Valve Infection: Organisms, Sequela, & Treatment - Oh My! Andrew Wang 11:25–11:35 am Prosthetic Valve Complications: Challenges in Diagnosis and Management Prosthetic Valve Surveillance - Are the Guidelines Appropriate? Pamela Douglas Hall H (Main Tent) Room 5A Hall H (Main Tent) Room 33C Room 11A Room 11A 9 Duke at ACC 2015 Sunday, March 15 11:39–11:51 am Clinical Trial Update: Acute Coronary Syndromes 2014 TRILOGY and PLATO - Prasugrel and Ticagrelor in the Medical Management of ACS Magnus Ohman 12:30–12:36 pm Recent Controversial Trials: Adopt Them or Ignore Them? IABP-SHOCK 2: Ignore the Trial Magnus Ohman 12:30–1:45 pm Pericardial Diseases: Non-Invasive Imaging Pamela Douglas, co-chair 1:24–1:30 pm Recent Controversial Trials: Adopt Them or Ignore Them? CathPCI Registry Door-to-Balloon Time: Shorter Time will Cut Hospital Mortality Christopher Granger 1:30–2:00 pm Sensitivity Matters, But How Much? Troponin testing in patients presenting with signs and symptoms suggestive of ACS Kristin Newby 2:00–3:30 pm The Big League: Around the Horn With Surgical Heavy Hitters Robert Jaquiss, panelist 2:53–3:00 pm Future of CV Surgery, EP, Interventional Cardiology What Do We Expect from the Best RCTs to be Completed in 2015-2016: Cardiology Eric Peterson 3:45–4:30 pm Poster Presentations Blood Pressure and Risk for Stroke or Bleeding Events in Patients with Atrial Fibrillation: Results from the Orbit AF Study Sreekanth Vemulapalli, Sunghee Kim, Laine Thomas, Gregg Fonarow, Michael Ezekowitz, Peter Kowey, Paul Chang, Manesh Patel, Jonathan Piccini, Kenneth Mahaffey, Alan Go, Bernard Gersh, Eric Peterson Room 6A Room 8 Room 2 Room 8 Expo Hall 1147 Room 31C Room 20D Poster Hall B1 Alpha-2c Adrenergic Receptor Polymorphism Interacts with Beta-Blocker Dose Effect on Heart Failure Outcomes Differently in Black Race: Results from the HF-ACTION DNA Substudy Kishan Parikh, Mona Fiuzat, Megan Neely, Tariq Ahmad, Michael Felker, Ileana Pina, Kirkwood Adams, Mark Donahue, William Kraus, David Whellan, Christopher O’Connor Post-Hospital Outcomes in Patients with Acute Myocardial Infarction Complicated by Cardiogenic Shock: Findings from the ACTION Registry-GWTG Rashmee Shah, Tracy Wang, Anita Chen, Laine Thomas, Benjamin Scirica, Timothy Henry, Nadia Sutton, James Fang, James de Lemos, Christopher Granger Apixaban Following Acute Coronary Syndromes Among Patients with Prior Stroke: Insights from the APPRAISE-2 Trial Matthew Sherwood, Renato Lopes, Jie-Lena Sun, Robert Harrington, Lars Wallentin, Daniel Laskowitz, Stefan James, Shaun Goodman, Harald Darius, Basil Lewis, Danny Liaw, Michael Gibson, John Alexander Increased Non-Alternans Repolarization Variability of Intracardiac Electrogram Precedes Onset of Spontaneous Ventricular Arrhythmias in Patients with Implantable Defibrillator Yuliya Krokhaleva, Divyang Patel, Hemal Shah, Vladimir Shusterman, Samir Saba, Jan Nemec 10 Duke at ACC 2015 Duke at ACC 2015 Sunday, March 15 Poster Presentations Impaired Left Ventricular Global Longitudinal Strain in Patients with Heart Failure with Preserved Ejection Fraction: Insights from the RELAX Trial Adam DeVore*, Steven McNulty, Fawaz Alenezi, Mads Ersboll, Jae Oh, Grace Lin, Margaret Redfield, Gregory Lewis, Marc Semigran, Kevin Anstrom, Adrian Hernandez, Eric Velazquez Elevated Galectin-3 Does Not Predict Benefit from Mineralocorticoid Receptor Antagonist Use in Patients with Chronic Heart Failure Due to Left Ventricular Systolic Dysfunction Parul U. Gandhi, Shweta Motiwala, Arianna Belcher, Hanna Gaggin, Rory Weiner, Aaron Baggish, Mona Fiuzat, Hans-Peter Brunner-La Rocca, James Januzzi Prognostic Value of Baseline and Changes in Circulating Soluble ST2 Levels and the Effects of Nesiritide in Acute Decompensated Heart Failure Wai Hong Wilson Tang, Amy Hsu, Adrian Hernandez, Javed Butler, Marco Metra, Michael Felker, Adriaan Voors, Richard Troughton, Roger Mills, John McMurray, Paul Armstrong, Robert Califf, Christopher O’Connor, Randall Starling Interleukin-6 Is Associated with, but Does Not Independently Predict, Mortality in Acute Heart Failure: An ASCEND-HF Substudy Antonio Perez, Justin Grodin, Adrian Hernandez, Javed Butler, Marco Metra, Michael Felker, Adriaan A. Voors, John McMurray, Paul Armstrong, Robert Califf, Randall Starling, Christopher O’Connor, Wai Hong Tang Association Between Prior Revascularization and Outcomes After STEMI: Results from the National Cardiovascular Data Registry Luis Gruberg, Anne Hellkamp, Laine Thomas, James de Lemos, Benjamin Scirica, Anthony Hilliard, Jonathan Enriquez, Amr Mohsen, Tracy Wang 3:45–4:30 pm ACC Poster Moderator Jonathan Piccini 3:45–4:30 pm Moderated Poster Session Post-Marketing Pharmacovigilance Study for the Active Detection and Evaluation of Major Bleeding in Rivaroxaban Users with Non-Valvular Atrial Fibrillation Sally Tamayo, Manesh Patel, Zhong Yuan, Kathleen Hopf, Frank Peacock 4:15–4:25 pm FIT Clinical Decision Making: Moderated Poster Session III To Shunt or Not To Shunt, That Is the Question: The Platypnea-Orthodeoxia Syndrome Michael Klein, Todd Kiefer, Eric Velazquez 4:45–6:00 pm Case Reviews: Learning from PCI Complications Sunil Rao, co-chair Moderated Poster Theater Poster Hall B1 Moderated Poster Theater Poster Hall B1 Moderated Poster Theater Poster Hall B1 Room 6D 11 Duke at ACC 2015 Monday, March 16 8:00–9:30 am Can Registries Improve the Quality of Arrhythmia Care? Sana Al-Khatib, co-chair 8:00–9:30 am MOC Part IV The Easy Way: No Registries, No Problem Sunil Rao, group moderator 8:00–9:30 am MOC Part IV The Easy Way: No Registries, No Problem Coronaries/Catheterization James Tcheng 8:05–8:15 am Cardio-Oncology Intensive ACC Talk: Cardio-Oncology - Why is it Important Now? The Cardiologist’s Perspective Pamela Douglas 8:15–8:25 am Joint Session of the American College of Cardiology/New England Journal of Medicine Late-Breaking Clinical Trials Effectiveness of Surgical Ablation of Atrial Fibrillation during Mitral Valve Surgery: A Randomized Clinical Trial from the Cardiothoracic Surgical Trials Network A. Gillinov, Annetine Gelijns, Michael Parides, Joseph DeRose, Alan Moskowitz, Pierre Voisine, Gorav Ailawadi, Denis Bouchard, Peter Smith, Michael Mack, Michael Acker, John Mullen, Helena Chang, John Puskas, David Adams, Keith Horvath, Steven Bolling, Robert Michler, Nancy Geller, Ellen Moquete, Wendy Taddei-Peters, Patrick O’Gara, Eugene Blackstone, Michael Argenziano 8:50–9:15 am Core Curriculum: Landmark Trials in CAD Landmark Trials in the Management of the Stable Ischemic Heart Patient Tracy Wang 9:00–9:12 am Highlighted Original Research: Valvular Heart Disease and the Year in Review Impact of Baseline Left Ventricular Function and Aortic Valve Gradient on Outcomes in Patients Treated with Transcatheter Aortic Valve Replacement: Results from the TVT Registry Suzanne Baron, Suzanne Arnold, Howard Herrmann, David Holmes, Adnan Chhatriwalla, Keith Allen, Wilson Szeto, Sreekanth Vemulapalli, Sean O’Brien, Dadi Dai, David Cohen 9:45–10:30 am Poster Presentations Impact of Proton Pump Inhibitor Use on the Comparative Safety and Effectiveness of Prasugrel versus Clopidogrel: Insights from TRANSLATE-ACS Larry Jackson*, Eric Peterson, Lisa McCoy, Christine Ju, Marjorie Zettler, Brian Baker, John Messenger, Douglas Faries, Mark Effron, David Cohen, Tracy Wang Room 1B 30B 30B Room 7B Hall H (Main Tent) Room 20C Room 11A Poster Hall B1 Reassessment of Cardiac Function and Implantable Cardioverter-Defibrillator Use Among Medicare Patients with Low Ejection Fraction After Myocardial Infarctionr Sean Pokorney*, Amy Leigh Miller, Anita Chen, Laine Thomas, Gregg Fonarow, James de Lemos, Sana Al-Khatib, Eric Peterson, Tracy Wang Are There Differences in Implantable Cardioverter-Defibrillator Counseling Rates Among Eligible Patients Hospitalized for Heart Failure? National Results from the American Heart Association’s Get with the Guidelines- Heart Failure Program Paul Hess, Adrian Hernandez, Deepak Bhatt, Anne Hellkamp, Clyde Yancy, Lee Schwamm, Eric Peterson, Philip Schulte, Gregg Fonarow, Sana Al-Khatib 12 Duke at ACC 2015 Duke at ACC 2015 Monday, March 16 9:45–10:30 am Poster Hall B1 Poster Presentations Racial/Ethnic Differences in Atrial Fibrillation Symptoms, Treatment Patterns, and Outcomes: Insights from Outcomes Registry for Better Informed Treatment for Atrial Fibrillation (ORBIT-AF) Registry Harsh Golwala, Larry Jackson*, DaJuanicia Simon, Gregg Fonarow, Paul Chang, Bernard Gersh, Alan Go, Elaine Hylek, Peter Kowey, Kenneth Mahaffey, Laine Thomas, Eric Peterson, Jonathan Piccini, Kevin Thomas Comparative Effectiveness of Cardiac Resynchronization Therapy with Defibrillator versus Defibrillator Alone in Heart Failure Patients with Moderate to Severe Chronic Kidney Disease Daniel Friedman, Jagmeet Singh, Jeptha Curtis, Wai Hong Tang, Haikun Bao, Erica Spatz, Adrian Hernandez, Uptal Patel, Sana Al-Khatib Echocardiography Core Lab Reproducibility of Cardiac Safety Assessments in Cardio-Oncology Michel Georges Khouri, Bonnie Ky, Gary Dunn, Theodore Plappert, Virginia Englefield, Eric Yow, Huiman Barnhart, Martin St. John Sutton, Pamela Douglas Anti-Hyperglycemic Medication Use Among Medicare Beneficiaries with Heart Failure, Diabetes, and Chronic Kidney Disease Priyesh Ashok Patel, Li Liang, Prateeti Khazanie, Bradley Hammill, Gregg Fonarow, Paul Heidenreich, Clyde Yancy, Deepak Bhatt, Lesley Curtis, Adrian Hernandez Response to Exercise Training and Outcomes in Heart Failure Patients with Diabetes Mellitus: Insights from HF-ACTION Adam Banks, Robert Mentz, Amanda Stebbins, Catherine Mikus, Phillip Schulte, Jerome Fleg, Lawton Cooper, Steven Keteyian, Ileana Pina, Dalane Kitzman, Mona Fiuzat, David Whellan, William Kraus, Christopher O’Connor Temporal Trends in Cardiac Rehabilitation Referral Among Patients Hospitalized with Heart Failure: Analysis from American Heart Association Get With The Guidelines-Heart Failure Registry Harsh Golwala, Ambarish Pandey, Christine Ju, Javed Butler, Clyde Yancy, Deepak Bhatt, Adrian Hernandez, Gregg Fonarow Diuretic Response in Acute Heart Failure: An Analysis from ASCEND-HF Jozine Ter Maaten, Allison Dunning, Mattia Valente, Kevin Damman, Justin Ezekowitz, Robert Califf, Randall Starling, Christopher O’Connor, Phillip Schulte, Jeffrey Testani, Adrian Hernandez, Wai Hong Tang, Adriaan Voors Body Mass Index and Outcomes with Apixaban versus Warfarin in Patients with Atrial Fibrillation in the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) Trial Roopinder Sandhu, Justin Ezekowitz, Ulrika Andersson, John Alexander, Christopher Granger, Sigrun Halvorsen, Michael Hanna, Ziad Hijazi, Petr Jansky, Renato Lopes, Lars Wallentin 9:45–10:45 am Driving Towards a Same-Day Discharge Strategy for PCI – What are Key Considerations? Sunil Rao 10:45–10:55 am Late-Breaking Clinical Trials V: Interventional Cardiology The Total Trial: A Randomized Trial Of Routine Aspiration Thrombectomy With Percutaneous Coronary Intervention (PCI) Versus PCI Alone In Patients With St-elevation Myocardial Infarction Undergoing Primary PCI Sanjit Jolly, TOTAL Investigators Expo Hall 3545 Hall H (Main Tent) 13 Duke at ACC 2015 Monday, March 16 11:00–11:12 am Highlighted Original Research: Acute Coronary Syndromes and the Year in Review Socioeconomic Disparities and Quality of In-Hospital Care After Myocardial Infarction in the National Cardiovascular Data Registry Jacob Udell, Nihar Desai, Shuang Li, Laine Thomas, Wenying Zhang, James de Lemos, Matthew Roe, Deepak Bhatt 11:15–11:25 am Late-Breaking Clinical Trials V: Interventional Cardiology Bivalirudin Infusion Compared To Unfractionated Heparin In Patients With Acute Coronary Syndromes Undergoing Invasive Management: Results From The Minimizing Adverse Haemorrhagic Events By Transradial Access Site And Systemic Implementation Of Angiox (matrix) Anti-thrombin Program Marco Valgimigli, MATRIX group 11:15–11:27 am Highlighted Original Research: Acute Coronary Syndromes and the Year in Review Revascularization Trends in Patients with Diabetes Mellitus and Multivessel Coronary Artery Disease Presenting with Non-St Elevation Myocardial Infarction: Insights from the NCDR®. Ambarish Pandey, Darren McGuire, James de Lemos, Sandeep Das, Jarett Berry, Emmanouil Brilakis, Subhash Banerjee, Steven Marso, Gregory Barsness, DaJuanicia Simon, Matthew Roe, Abhinav Goyal, Mikhail Kosiborod, Ezra Amsterdam, Dharam Kumbhani 11:45–11:55 am Integrating Device and Drug Care in STEMI Deciding among Clopidogrel, Prasugrel, or Ticagrelor Magnus Ohman 11:45–11:57 am Highlighted Original Research: Acute Coronary Syndromes and the Year in Review Temporal Trends in Care and Outcomes of Patients with Cardiogenic Shock Undergoing Percutaneous Coronary Intervention: A Report from the NCDR® Siddharth Wayangankar, Sripal Bangalore, Lisa McCoy, Hani Jneid, Wassef Karrowni, Faisal Latif, Paramita Saha Chaudhuri, Eric Peterson, Habib Dakik, Laura Mauri, Matthew Roe, John Messenger, Debabrata Mukherjee, Andrew Klei 12:00–12:10 pm Integrating Device and Drug Care in STEMI Case Presentation: The Challenges of Primary PCI Manesh Patel 12:30–12:45 pm Featured Clinical Research II Reduction in Total (First and Recurrent) Cardiovascular Events with Ezetimibe/Simvastatin compared with Simvastatin Alone post Acute Coronary Syndromes in the IMPROVE-IT Trial Sabina Murphy, Christopher Cannon, Robert Giugliano, Michael Blazing, Thomas Musliner, Andrew Tershakovec, Jennifer White, Kelly Im, Naveen Deenadayalu, Haral Darius, Witold Ruzyllo, Andrew Tonkin, Uma Kher, Robert Califf, Eugene Braunwald 12:45–1:00 pm Treatment Strategies for Hospitalized Heart Failure Patients Diuretic Strategies in Acute Heart Failure: Does DOSE Matter? Michael Felker 12:51–12:55 pm Late-Breaking Clinical Sessions Deep Dive PROspective Multicenter Imaging Study for Evaluation of chest pain (The PROMISE Trial) Pamela Douglas Room 20A Hall H (Main Tent) Room 20A Room 6D Room 20A Room 6D Room 6E Room 5A Hall H (Main Tent) 14 Duke at ACC 2015 Duke at ACC 2015 Monday, March 16 1:18–1:23 pm Logistical Challenges in STEMI Out of Hospital Identification of STEMI Christopher Granger 2:00–2:18 pm Myocardial Tissue Characterization by CMR Replacement Fibrosis/Scar Imaging Igor Klem 2:00–3:30 pm Optimizing PCI Care Processes Sunil Rao, co-chair 4:21–4:39 pm Risk Stratification in CAD: Is CMR the Gold Standard? Chronic Scar Raymond Kim Room 20A Room 2 Room 6F Room 2 15 Contact Information Martin Hunicutt, Assistant Director Cardiovascular, Imaging, & Oncology Business Development Phone: 919.668.9010 Mobile: 919.316.8343 Email: [email protected] Visit us at DCRI.org or via our company page on LinkedIn. DCRI Communications February 2015