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CURRICULUM VITAE 1. PERSONAL DETAILS Last Name: First, Middle Name: Date of Birth: Place of Birth: Nationality: Marital Status: Address: Language spoken & written: Gasche-Soccal Paola, Marina 6 December 1962 Rome, Italy Swiss & Italian married Hôpital Cantonal Universitaire de Genève Service de Pneumologie, 7ème étage, 4, Rue Gabrielle-Perret-Gentil CH-1211 Genève 14 Phone: +41 22 372 9911 FAX : +41 22 372 9909 French, english, italian & german 2. EDUCATION & CERTIFICATIONS Places: Geneva University Hospitals-Switzerland Stanford University Medical Center-CA-USA March 1982 March 1990 June 1998 June 1998 Federal Maturity Diploma, Fribourg. Swiss Federal Diploma of Medicine, Medical School, Geneva University Medical Doctor Diploma, Medical School, Geneva University FMH Internal Medicine FMH Pulmonary Medicine Privat-Docent (venia legendi), Medical School, Geneva University June 2010 Medical Doctoral Thesis: “Relationship between oxygen consumption, inflammation and pulmonary shunt during acute lung injury” (Thesis # 9932) - Medical School, Geneva University Venia Legendi Thesis: “Lung transplantation: short and long-term complications” - Medical School, Geneva University 3. POST-GRADUATE MEDICAL TRAINING & CURRENT POSITION 01.10. 2004-01.10.2011: Médecin-adjoint agrégée au Chef de Service, Service de Pneumologie et Service de Chirurgie Thoracique, HUG 01.10. 2004-01.06.2010: Médecin-adjoint au Chef de Service, Service de Pneumologie et Service de Chirurgie Thoracique, HUG 1.10.2000-30.09.2004: Chef de Clinique, Service de Pneumologie et Service de Chirurgie Thoracique, HUG 1.10.1998-30.09.2000: Post-doctoral Fellow, Division of Pulmonary and Critical Care Medicine, Stanford University Medical-Center-CA-USA (Prof. T. Raffin & Prof. J. Theodore) 1.10.1996-30.9.1998: Médecin-Interne, Division de Pneumologie, HUG 1.04.1996-30.9.1996: Chef de Clinique, Service de Néphrologie, HUG 1.10.1995-31.03.1996: Chef de Clinique, Service de Médecine, Hôpital Régional d’Yverdon 1.10.1994-30.9.1995: Chef de Clinique, Clinique de Médecine I, HUG 1.10.1992-30.9.1994: Médecin-Interne, Clinique de Médecine I, HUG 1.07.1990-30.09.1992: Médecin-Interne, Service de Pathologie Clinique, HUG 1.04.1990-30.06.1990: Médecin-Interne, Clinique de Médecine II, HUG MEMBERSHIP American Society of Transplantation International Society for Heart and Lung Transplantation The Transplantation Society European Society for Organ Transplantation Swiss Society of Transplantation Swiss Society of Pulmonary Medicine European Association for Bronchology and Interventional Pneumology OFFICIAL ACTIVITIES Member of the Ethics’ Committee for Clinical Research HUG Member of the Management Committee of Geneva-Lausanne Transplantation Center Research Coordinator for the HUG-CHUV Transplantation Center Member of the Swiss Transplant Cohort Study Scientific Committee Member of the Committee of the Swiss Society of Pulmonary Medicine Member of the HUG Medical Representatives Committee President of the HUG “médecin-adjoint” association (AMAHUG) Treasurer of the European Association for Interventional Bronchoscopy Member of the HUG Establishment Medical Council since 2001 since 2004 2006-2011 since 2008 since 2009 since 2009 since 2010 since 2011 since 2011 AWARDS McCormick Research Award (20 000 US$) Stanford University Medical Center-US 3rd award of the Swiss Society of Transplantation 1999 2000 PUBLICATIONS (LAST 5 YEARS) PEER REVIEWED ARTICLES 1. Rhinovirus Genome Variation during Chronic Upper and Lower Respiratory Tract Infections. Tapparel C, Cordey S, Junier T, Farinelli L, Van Belle S, Soccal PM, Aubert JD, Zdobnov E, Kaiser L. PLoS One. 2011;6(6):e21163. Epub 2011 Jun 21. 2. Graft-versus-host disease is the major determinant of humoral responses to the AS03adjuvanted influenza A/09/H1N1 vaccine in allogeneic hematopoietic stem cell transplant recipients. Mohty B, Bel M, Vukicevic M, Nagy M, Levrat E, Meier S, Grillet S, Combescure C, Kaiser L, Chalandon Y, Passweg J, Siegrist CA, Roosnek E; Blood and Marrow Transplant Program; Geneva University Hospitals H1N1 study group. Collaborators (41):Siegrist CA, Posfay-Barbe K, Meier S, Bel M, Grillet S, Sealy G, Charvat S, Demeules J, Verdon M, Combescure C, Hirschel B, Calmy A, Nguyen A, Delhumeau-Cartier C, Ambrsioni J, Gabay C, Guerne PA, Seebach J, Ribi C, Villard J, Dietrich PY, George AC, Favet L, van Delden C, Morard I, Mentha G, Giostra E, Hadaya K, Martin PY, Soccal P, Berney T, Noble S, Mohty B, Nagy M, Chalandon Y, Roosnek E, Passweg J, Kaiser L, Yerly S, Thomas Y, Wunderli W. Haematologica. 2011 Jun;96(6):896-904. Epub 2011 Mar 21. 3. Impact of synthetic and biologic disease-modifying antirheumatic drugs on antibody responses to the AS03-adjuvanted pandemic influenza vaccine: a prospective, openlabel, parallel-cohort, single-center study. 4. Gabay C, Bel M, Combescure C, Ribi C, Meier S, Posfay-Barbe K, Grillet S, Seebach JD, Kaiser L, Wunderli W, Guerne PA, Siegrist CA; H1N1 Study Group. Collaborators (29) Ambrosioni J, Berney T, Calmy A, Chalandon Y, Charvat S, Delhumeau-Cartier C, Demeules J, Dietrich PY, Favet L, George AC, Giostra E, Hadaya K, Hirschel B, Martin PY, Mentha G, Mohty B, Morard I, Nagy M, Nguyen A, Noble S, Passweg J, Roosnek E, Sealy G, Soccal P, Thomas Y, van Delden C, Verdon M, Villard J, Yerly S. Arthritis Rheum. 2011 Jun;63(6):1486-96. 5. Respiratory viruses in lung transplant recipients; a critical review and pooled analysis of clinical studies. Diem Lan Vu, Pierre-Olivier Bridevaux, John-David Aubert, P.M. Soccal, L.Kaiser. Am J Transplant 2011;11(5):1071-8 (IF:6.433) 6. Combined Pancreatic Islet–Lung Transplantation: A Novel Approach to the Treatment of End-Stage Cystic Fibrosis. L. Kessler, S. Bakopoulou, R. Kessler, G. Massard, N. Santelmo,M. Greget, F. Moreau,O. Helms, D. Bosco, P. Gasche-Soccal, P. Morel, P. Wolf, T. Berney, on behalf of the GRAGIL group. Am J Transplant 2010; 10(7):17071712 (IF:6.433) 7. Upper and lower respiratory viral infections and acute graft rejection in lung transplant recipients. Paola M. Soccal, John-David Aubert, Pierre-Olivier Bridevaux, Jorge Garbino, Yves Thomas, Thierry Rochat, Pascal Meylan, Caroline Tapparel, Laurent Kaiser. Clin Inf Dis Jul 15;51(2):163-70 (IF : 8.26) 8. The puzzling coexistence of different histological changes in the same transplanted lung. Robert JH, Soccal PM, Romand J, Rochat T, Pache JC. Swiss Med Wkly. 2010;140:92-94 (IF : 1.436) 9. Low incidence of severe respiratory syncytial virus infections in lung Transplant Recipients despite the absence of specific therapy. Ilker Uçkay, Paola M. GascheSoccal, Laurent Kaiser, Richard Stern, Jesica Mazza-Stalder, John-David Aubert, Christian Van Delden. J Heart Lung Transplant. 2010;29:299-305 (IF: 3.32) 10. Survival Impact of lung transplantation for chronic obstructive pulmonary disease. Samir Lahzami, Pierre-Olivier Bridevaux, Paola M. Soccal, John Robert, John Wellinger, John-David Aubert. Eur Respir J. 2009;dec (IF :5.349) 11. Titrated sedation with propofol or midazolam for flexible bronchoscopy: a randomised trial. Gregory Clark, Marc Licker, Alain Bigin Younossian, Pierre-Olivier Bridevaux, Paola M. Soccal, Jean-Georges Frey, Thierry Rochat, John Diaper. François Clergue, Jean-Marie Tschopp. European Respiratory Journal. 2009;34: 1277-1283 (IF :5.349) 12. Population pharmacokinetics of valganciclovir in solid organ transplant recipients. N. Perrottet, C. Csajka, M. Pascual, O. Manuel, F. Lamoth, P. Meylan, J.D. Aubert, P. Soccal, L. A. Decosterd, J. Biollaz, T. Buclin Antimicrobial agents and chemotherapy.2009;53:3017-3023 (IF:4.3) 13. New Respiratory Enterovirus and Recombinant Rhinovirus among circulating picornaviruses. Caroline Tapparel, Thomas Junier, Daniel Gerlach, Sandra Van Belle, Lara Turin, Samuel Cordey, Kathrin Mühlemann, Nicolas Regamey, John-David Aubert, Paola M. Soccal, Philippe Eigenmann, Evgeny Zdobnov, Laurent Kaiser.Emerging Infectious Diseases. 200915:719-726(IF:5.75) 14. Respiratory viruses in bronchoalveolar lavage: a hospital-based cohort study. J. Garbino, Paola M. Soccal, John-David Aubert, Thierry Rochat, Pascal Meylan, Yves Thomas, Caroline Tapparel, Pierre-Olivier Bridevaux, Laurent Kaiser. Thorax. 2009;64:399-404 (IF:6.2) 15. Neuroendocrine proliferation after lung transplantation Patrick O. Myers, Paola M. Soccal, John H. Robert, Jean-Claude Pache, MD, Massimo Bongiovanni. J Heart Lung Transplant. 2009;28:406-408 (IF:2.81) 16. Margaret W. Gerbase, Paola M. Soccal, Anastase Spiliopoulos, Laurent P. Nicod, T. Rochat. Long-term health-related quality of life and walking capacity of lung recipients with and without bronchiolitis obliterans syndrome J Heart Lung Transplant 2008; 27(8):898-904 (IF: 2.81) 17. C.Tueller, H. Stricker, P.M.Soccal, M.Tamm, J-D. Aubert, M. Maggiorini, L. Nicod. Epidemiology of Pulmonary Hypertension: New Data from the Swiss Registry Swiss Med Wkly 2008; 138(25-26):379-84 (IF: 1.34) 18. Garbino J., Inoubli S., Mossdorf E., Weber R. Tamm M., Soccal P., Aubert JD., Bridevaux PO., TapparelC., Kaiser L., and the Swiss HIV Cohort Study. Respiratory viruses in HIV-infected patients with suspected respiratory opportunistic infection. AIDS 2008 30; 22(6):701-5. (IF 5.6) 19. L. Kaiser, J-D. Aubert, J-C. Pache, C. Deffernez, T. Rochat, J. Garbino, W. Wunderli, P. Meylan, S. Yerly, L. Perrin, I. Letovanec, L. Nicod, C. Tapparel, P.M. Soccal. Chronic Rhinoviral Infection in Lung Transplant Recipients. Am J Respir Crit Care Med. Am J Respir Crit Care Med 2006; 174(12):1392-9. (IF. 8.69) 20. J. Garbino, S. Crespo, J-D Aubert, Th. Rochat, B. Ninet, C. Deffernez, W. Wunderli, JC. Pache, P. M. Soccal, L. Kaiser. A prospective hospital-based study of the clinical impact of non-severe acute respiratory syndrome (Non-SARS)-related human coronavirus infection. Clin Infect Dis 2006;43(8):1009-1015). (IF 6.51) 21. Gasche Y., Soccal P.M., Kanemitsu M., Copin J-C. Matrix metalloproteinases and diseases of the central nervous system with a special emphasis on ischemic brain. Frontiers in Bioscience (in press). Front Biosci 2006;11:1289-301. (IF. 3.23) 22. Brauchlin Andreas E., Soccal Paola M., Rochat Thierry, Spiliopoulos Anastase, Nicod Laurent P., Trindade Pedro T. Severe left ventricular dysfunction secondary to primary pulmonary hypertension: bridging therapy with bosentan before lung transplantation. J Heart Lung Transplant 2005; 24(6):777-80. (IF: 2.81) 23. Garbino Jorge, Gerbase Margaret W., Wunderli Werner, Deffernez Christelle, Thomas Yves, Rochat Thierry, Ninet Beatrice, Schrenzel Jacques, Yerly Sabine, Perrin Luc, Soccal Paola M., Nicod Laurent and Kaiser Laurent. Lower Respiratory Viral Illnesses Improved Diagnosis by Molecular Methods and Clinical Impact. Am J Respir Crit Care Med. 2004 Dec 1;170(11):1197-203. (IF. 8.12)