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Oct 31, 2014 CURRICULUM VITAE NAME: Nena Matijevic, Ph.D., Pharm.D., M.S., C.L.S. PRESENT TITLE: Professor Department of Surgery and Center for Translational Injury Research ADDRESS: The University of Texas Medical School at Houston Department of Surgery 6431 Fannin, MSB 5.240 Houston, Texas 77030-1503 Telephone: (713) 500-6807 Fax: (713) 500-0685 Email: [email protected] CITIZENSHIP: U.S.A. UNDERGRADUATE EDUCATION: 1974 Pharm.D. University of Belgrade, Faculty of Pharmacy, Belgrade, Yugoslavia GRADUATE EDUCATION: 1986 M.S. in Medical Sciences – Hematology. University of Belgrade, Medical School, Belgrade, Yugoslavia. Thesis:“Platelet functions in patients with idiopathic thrombocytopenic purpura (ITP).” POSTGRADUATE TRAINING: 1988 Specialist in Medical Biochemistry (Clinical Chemistry, CLS) University of Belgrade, Faculty of Pharmacy, Belgrade, Yugoslavia Thesis: “Protein C activity in patients on oral anticoagulant therapy. DOCTORAL STUDIES: 1998 Nena Matijevic, PhD Ph.D. in Medical Sciences – Hematology University of Belgrade, Medical School, Belgrade, Yugoslavia. Dissertation: “Expression of prostaglandin H2 synthase and thromboxane A2 synthase in megakaryocytes and platelets” Page 1 ACADEMIC APPOINTMENTS: 1974 – 1975 Regular Pharmaceutical Practice, Belgrade City Hospital Pharmacy, Belgrade, Yugoslavia 1975 – 1976 Central Clinical Chemistry Laboratory, Belgrade City Hospital, Belgrade, Yugoslavia 1976 – 1988 Hemostasis Laboratory Manager, Belgrade City Hospital, Belgrade, Yugoslavia 1988 – 1992 Hemostasis Laboratory Director, University Clinical Center, Department of Hematology, Belgrade, Yugoslavia 1992 – 2000 Research Instructor, University of Texas Houston Health Science Center, Medical School, Internal Medicine, Hematology and Vascular Biology Research Center, Houston, Texas 1996 – 2008 ARIC (Atherosclerosis Risk in Communities) Central Hemostasis Laboratory Director, University of Texas, Medical School, Internal Medicine, Hematology, Houston, Texas 2000 – 2007 Assistant Professor in Medicine, University of Texas, Medical School, Internal Medicine, Hematology and Vascular Biology Research Center, Houston, Texas 2001 – 2008 Flow Cytometry Laboratory Director, University of Texas, Medical School, Internal Medicine, Hematology and Vascular Biology, Houston, Texas 2007 – 2008 Associate Professor in Medicine (Research, NT), University of Texas, Medical School, Internal Medicine, Hematology, Houston, Texas 2008 – Present Flow Cytometry Laboratory Director, University of Texas, Medical School, Department of Surgery, Houston, Texas 2008 – 2013 Associate Professor (Research, NT), University of Texas, Medical School, Department of Surgery and Center for Translational Injury Research, Houston, Texas 2008 – Present Hemostasis Laboratory Director, University of Texas, Medical School, Department of Surgery and Center for Translational Injury Research, Houston, Texas Nena Matijevic, PhD Page 2 2013 – Present Professor (Research, NT), University of Texas, Medical School, Department of Surgery and Center for Translational Injury Research, Houston, Texas PROFESSIONAL ORGANIZATIONS/SOCIETY MEMBERSHIPS: 2012 - Present The North American Society on Thrombosis and Hemostasis 1999 – Present American Society of Hematology 2000 – Present International Society on Thrombosis and Haemostasis 2006 – 2008 International Clinical Cytometry Society 2006 – 2009 Mediterranean League against Thromboembolic Disease SCIENTIFIC JOURNAL REVIEWER: Circulation Journal of Thrombosis and Hemostasis Journal of Neurology Transfusion Thrombosis Research ARIC (Atherosclerosis Risk in Communities) Study Publications CHS (Cardiovascular Health Study) Publications ARIC Carotid MRI Study Publications SERVICE ON NATIONAL GRANT REVIEW PANELS, STUDY SECTIONS, COMMITTEES: 1996 – 2005 Nena Matijevic, PhD Laboratory Committee, ARIC Study, NIH/National Heart Lung and Blood Institute Page 3 2004 – 2008 Laboratory Committee, ARIC Carotid MRI Study, NIH/National Heart Lung and Blood Institute 2004 – 2008 Quality Control Committee, ARIC Carotid MRI Study, NIH/National Heart Lung and Blood Institute 2008 – 2010 PROMMTT (Prospective Observational Multicenter Massive Transfusion sTudy) Laboratory Committee, US Department of Defense 2009 – Present PROPPR (Pragmatic Randomized Optimal Platelet and Plasma Ratios) Study Laboratory Committee, NIH/NHLBI THE UNIVERSITY OF TEXAS MEDICAL SCHOOL COMMITTEES/ACTIVITIES: 2011 – Present Faculty Senate 2011 – Present Committee on Committees 2011 – Present Medical Student Interviewer CURRENT GRANT SUPPORT: 2010 – 2014 Co-Investigator PI: Suzanne May, PhD NIH/NHLBI via ROC (5U01HL077863) Title: Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) $50,088,890 GRANTS PENDING: 2014 – 2018 Nena Matijevic, PhD Co-Investigator PI: Marie Francoise Doursout, PhD NHLBI Title: Impact of Microparticle Pro-Inflammatory and Pro-Coagulant Properties on Sepsis-Induced Endothelium Dysfunction. $1,440,936 Page 4 PAST GRANT SUPPORT: 1992 – 2006 Co-Investigator PI: Kenneth K Wu, MD NIH/NHLBI, N01 Title: Atherosclerosis Risk in Communities (ARIC) Study: Morbidity/Mortality Follow-up: Central Hemostasis Laboratory 1998 - 2002 Co-Investigator PI: Aaron Folsom, MD, UMNSPH, NIH/NHLBI, R01 Title: Longitudinal Investigation of Thromboembolism Etiology (LITE). 1999 – 2004 Co-Investigator, Core Lab Principal Investigator: Kenneth K Wu, MD, PhD NIH/NHLBI, P50 Title: Prostaglandins in Cerebral Vascular Thrombosis. 2004 – 2009 Co-investigator; PI for cellular studies PI: Eric Boerwinkle, PhD NIH/NHLBI (5U01HL075572) Title: Atherosclerosis, Plaque and CVD in Communities $1,404,859 2009 – 2010 Co-Investigator PI: Jodie Conyers, PhD US Department of Defense, USAMRMC (W81XWH-07-2-0031) Title: Texas Science, Humanitarian Intervention, Education and Leadership in Disaster (TexSHIELD) $1,286,794 2009 – 2010 Co-Investigator PI: John B Holcomb, MD US Department of Defense Title: Early Whole Blood for Patients Requiring Massive Transfusion after Major Trauma 2010 – 2011 Co-investigator PI: Mohammad Hossein Rahbar, PhD US Department of Defense, USAMRMC (W81XWH-08-C-0712) Title: Coagulation Abnormalities in Severely Injured Patients (PROMMTT- Modification) $1,000,000 Nena Matijevic, PhD Page 5 2011 – 2012 2009 – 2013 Co-Investigator PI: Charles E Wade, PhD US Department of Defense, USAMRMC (W81XWH-11-1-0023) Title: Characterization and Application of a Large Model of Penetrating Ballistic Brain Injury $1,267,646 Co-investigator PI: Mohammad Hossein Rahbar, PhD US Department of Defense, USAMRMC (W81XWH-08-C-0712) Title: Prospective, Observational, Multicenter Major Trauma Transfusion study (PROMMTT) $10,031,550 PUBLICATIONS: A. ABSTRACTS 1. Pendic B, Matijevic N, Plecas V, Dragovic M. Effects of cytostatics commonly used for treatment of acute leukemia on platelet aggregation in vitro. 6th Meeting of Yugoslav Society of Hematology and Transfusiology, Portoroz. Abstract book. 1976. 2. Matijevic N, Pendic B, Zdravkovic M, Ivankovic D. The effect of aspirin on platelet aggregation in vivo and in vitro. VII Yugoslav Congress of Pharmacy, Ohrid, Abstracts. p.80. 1976. 3. Matijevic N, Sisic I, Korolija P, Pendic B. Estimation of hemostasis in elderly subjects treated with Complamin®. I Yugoslav Congress of Gerontologists, Belgrade, Abstract book. 1977. 4. Zdravkovic M, Matijevic N, Ivankovic D, Pendic B, Tubin M, Cvetkovic G. Platelet aggregation and gastrointestinal complications during the treatment of rheumatic fever with aspirin. XV Meeting of Internists, Symposium "Drugs and Health", Subotica. Abstract book. 1977. 5. Matijevic-Aleksic N, Pajevic M, Milutinovic Dj, Tomasevic R, Pendic B. The influence of platelet storage and temperature on platelet functions. III Yugoslav Congress of Hematology and Transfusiology, Sarajevo, 1978. Abstracts, p.153-154. 6. Jelic S, Bojic M, Dragovic M, Miletic V, Matijevic N, Plecas V. Leukemic phase of diffuse histiocytic lymphoma (Reticulum Cell Sarcoma). III Yugoslav Congress of Hematology and Transfusiology, Sarajevo. Abstracts, p.123-124. 1978. 7. Pajevic M, Matijevic N, Jelic S, Djuric D, Pendic B, Plecas V. Investigation of immunological and hemostatic parameters related to platelets transfusion in patients with Nena Matijevic, PhD Page 6 malignant hemopathies. III Yugoslav Congress of Hematology and Transfusiology, Sarajevo. Abstracts, p.151-152. 1978. 8. Miletic V, Jelic S, Gligorovic V, Matijevic N, Plecas V. Physicochemical properties and biologic effects of commercial gamma globulin preparations. III Yugoslav Congress of Hematology and Transfusiology, Sarajevo. Abstracts p.159-160. 1978. 9. Pendic B, Matijevic N. Cytostatics and platelet aggregation. III Yugoslav Congress of Hematology and Transfusiology, Sarajevo. Abstracts, p.230-231. 1978. 10. Savic S, Zdravkovic M, Najdanovic B, Ivankovic D, Ristic V, Madic R, Dimitrijevic I, Djordjevic G, Matijevic N. Les effets du Propranolol (Inderal) sur l' hypertension arterielle chez les malades avec des valeurs elevees de l' activite de la renine plasmatique. VII Congress International de Pharmacologie, Paris, France, 1978. 11. Savic S, Zdravkovic M, Najdanovic B, Ivankovic D, Djordjevic G, Matijevic N. The activity of plasma rennin and aldosterone in the essential hypertension and the effects of Propranolol on the former. International Symposium on Essential Hypertension, Herceg Novi, 1978. 12. Matijevic N, Miletic V, Pendic B. Characteristics of platelet aggregation induced by heataggregated immunoglobulins. VI Yugoslav Symposium of Immunology, Tara, 1979. 13. Matijevic N, Miletic V, Pendic B. Aggregation of human blood platelets with monomeric and aggregated immunoglobulins. II Meeting of Yugoslav Society of Hemostasis and Thrombosis, Belgrade, 1979. 14. Jelic S, Matijevic N, Miletic V. Platelet aggregation in vitro in the presence of mixed IgG and IgM cryoglobulins. II Meeting of Yugoslav Society of Hemostasis and Thrombosis, Belgrade, 1979. 15. Matijevic N, Petrovic M, Vidakovic B, Plecas V, Pendic B. Platelet function in cytostatics treated patients. VII Meeting of Yugoslav Society of Hematology and Blood Transfusion, Split, 1980. 16. Pendic B, Matijevic N, Dimitrijevic B, Pantic V. Action des agents da la chimiotherapie sur l’ aggregation plaquettaires in vitro. 18th International Congress of the Society of Hematology, Montreal, Canada. Abstract 1197, 1980. 17. Milenkovic Lj, Tomasevic R, Djuric D, Radovic M, Matijevic N. Comment on certain platelet preparation procedures for transfusion. Symposium "Current problems in health care of hematologic patients", Belgrade, 1980. 18. Matijevic-Aleksic N, Pendic B. Clinical use of platelet aggregation studies. VI Yugoslav Congress of Clinical Chemistry, Split, 1983. Nena Matijevic, PhD Page 7 19. 20. Pudar-Brankovic G, Matijevic-Aleksic N, Peric Lj, Mijalkovic D, Brankovic S. Platelet aggregation in patients with diabetes mellitus. Yugoslav Congress of Endocrinology, Novi Sad, 1984. Matijevic-Aleksic N, Rolovic Z, Pendic B. Platelet function in patients with idiopathic thrombocytopenic purpura. IV Yugoslav Congress of Hematology and Transfusiology, Skoplje, 1984. 21. Despotovic N, Paranos S, Matijevic-Aleksic N, Rosic D. Platelet aggregation abnormalities in patients with elevated IgE. Scientific Meeting of Serbian Academy of Sciences and Art, Division of Medical Sciences, "Specific Hypersensitivity of the Organism", Belgrade. Abstract book.1986. 22. Matijevic-Aleksic N, Petrovic M, Rajic M,Vidakovic B. Antithrombin III in patients with malignant hemopathies. V Yugoslav Congress of Hematology and Transfusiology, Maribor. Abstracts. 1986. 23. Matijevic-Aleksic N, Rolovic Z. Platelet aggregation in patients with idiopathic thrombocytopenic purpura. V Yugoslav Symposium on Hemostasis and Thrombosis, Novi Sad. Abstract book. 1987. 24. Matijevic-Aleksic N, Jovic B, Paranos S, Despotovic N. Influence of elevated concentrations of serum IgE on human platelet aggregation. 7th Yugoslav Congress of Clinical Chemistry, Novi Sad. Abstract book.1987. 25. Matijevic-Aleksic N, Petrovic M, Jovic B, Rajic M, Vidakovic B. Hemostasis inhibitors in patients with malignant hemopathies. VII Yugoslav Congress of Cancer, Novi Sad. Abstract book. 1987. 26. Petrovic M, Matijevic-Aleksic N, Plecas V, Radulovic S. Hemostasis abnormalities in malignant diseases. XXIV Meeting of Oncology and Radiology, Belgrade, 1987. 27. Matijevic-Aleksic N, Jelic Z, Majkic-Singh N. Protein C and oral anticoagulant therapy. II Dalmatian Meeting of Clinical Chemistry, Split. Abstract book. 1988. 28. Starcevic D, Matijevic-Aleksic N, Jelic-Ivanovic Z. C1-esterase inactivator in malignant diseases. II Dalmatian Meeting of Clinical Chemistry, Split. Abstract book. 1988. 29. Matijevic-Aleksic N, Petrovic M, Plecas V, Vidakovic B, Panajotovic-Jovic B. Comparison of hemostatic parameters in patients with malignant diseases. IX Meeting of Yugoslav Society of Hematology and Transfusiology, Novi Sad. Abstracts. 1988. 30. Matijevic N, Elezovic I, Rolovic Z. Plasma levels of thrombin-antithrombin (TAT) complex in patients with acute leukemia. VI Yugoslav Meeting of Society of Hemostasis and Thrombosis, Ljubljana. Abstracts. 1990. Nena Matijevic, PhD Page 8 31. Matijevic N, Elezovic I, Rolovic Z. Plasma levels of fibrinogen and fibrin degradation products in patients with acute leukemia. VI Yugoslav Meeting of Society of Hemostasis and Thrombosis, Ljubljana. Abstracts. 1990. 32. Elezovic I, Matijevic N, Rolovic Z. Plasma levels and activities of factor XIII in patients wuth acute leukemia. VI Yugoslav Meeting of Society of Hemostasis and Thrombosis, Ljubljana. Abstracts. 1990. 33. Matijevic-Aleksic N, Boskovic D, Rolovic Z. Control of oral anticoagulant therapy using two different thromboplastins. 11th International Congress on Thrombosis, Ljubljana. Abstracts.1990. 34. Matijevic-Aleksic N, Jelic-Ivanovic. Functional assay of Protein C in patients on oral anticoagulant therapy. 11th International Congress on Thrombosis, Ljubljana. Abstracts.1990. 35. Matijevic-Aleksic N, Elezovic I, Marisavljevic D, Colovic M, Rolovic Z. Thrombinantithrombin III complex in acute leukemia. 6th Yugoslav Congress of Hematology and Transfusiology, Zagreb. Bilten Hematol Transf 17:110, 1990 36. Elezovic I, Matijevic N, Boskovic D, Mijovic A, Tomin D, Colovic M, Novak A, Rolovic Z. Disseminated intravascular coagulation in patients with acute promyelocytic leukemia. 6th Yugoslav Congress of Hematology and Transfusiology, Zagreb, 1990, Bilten Hematol Transf 17:109, 1990 37. Matijevic-Aleksic N, Elezovic I, Rolovic Z, Dimcic Z, Stefanovic Lj. Laboratory manifestation of a lupus-like anticoagulant: case report. VIII Yugoslav Scientific Meeting of Alergology and Clinical Immunology, Kopaonik. Abstracts. 1990. 38. Matijevic-Aleksic N, Dimcic Z, Rolovic Z. Protein C and Protein S in systemic diseases. VIII Yugoslav Scientific Meeting of Alergology and Clinical Immunology, Kopaonik. Abstracts. 1990. 39. Elezovic I, Matijevic-Aleksic N, Jancic A., Markovic Lj., Bonaci-Nikolic B., Djordjevic S. Anticardiolipin antibodies in patients with immune thrombocytopenic purpura. VIII Yugoslav Scientific Meeting of Alergology and Clinical Immunology, Kopaonik. Abstracts. 1990. 40. Dimcic Z, Bukulica M, Djordjevic S, Matijevic-Aleksic N, Markovic Lj, Tanurdcic S, Djuric M. Hemostatic abnormalities in patients with systemic lupus erythematosus associated with a presence of anticardiolipin antibodies. VIII Yugoslav Scientific Meeting of Alergology and Clinical Immunology, Kopaonik. Abstracts. 1990. 41. Dimcic Z, Bonaci-Nikolic B, Markovic Lj, Matijevic-Aleksic N, Balaban J, Tanurdcic. A case of cerebral systemic lupus erythematosus associated with anticardiolipin antibodies. Nena Matijevic, PhD Page 9 VIII Yugoslav Scientific Meeting of Alergology and Clinical Immunology, Kopaonik. Abstracts. 1990. 42. Elezovic I, Matijevic-Aleksic N, Marisavljevic D, Suvajdic N, Rolovic Z. Fibrinolysis and fibrinogenolysis in acute leukemia. XIIIth Congress of the International Society on Thrombosis and Haemostasis, Amsterdam. Thromb Haemostas 65:895. 1991. 43. Matijevic-Aleksic N, Elezovic I, Suvajdic N, Rolovic Z. Levels of fibrinopeptide A and thrombin-antithrombin III complex in patients with acute leukemia. XIIIth Congress of the International Society on Thrombosis and Haemostasis, Amsterdam. Thromb Haemostas 65:1322. 1991. 44. Matijevic-Aleksic N, Dulic B, Rolovic Z. Markers of hemostasis activation after total hip replacement. 12th International Congress on Thrombosis, Florence, Italy. Abstracts P353.1992. 45. Simic N, Avramovic D, Matijevic-Aleksic N, Stevic S, Kalimanovska-Ostric D. Indobufen treatment of angina pectoris: effects on platelet aggregation. International meeting in Cardiology, Amsterdam.Abstracts.1992. 46. Aleksic, N. M., Sanduja, S. K., Long, C., Wu, K. K. Coordinate expression of prostaglandin H synthase and thromboxane A synthase in phorbol-induced differentiation of a megakaryocyte cell line (MEG-01). 35th Annual Meeting, The American Society of Hematology, St. Louis, MO, December 3-7. Blood, 82:suppl.1. 266. 1993. 47. Wu, K.K., Sanduja, S.K, Tsai, A.-L., and Matijevic-Aleksic, N. Quantitative analysis of prostaglandin H synthase (PGHS-1) decay in cells overxpressing PGHS-1. 9th International Conference on Prostaglandins and Related Compounds, Florence, Italy, June 6-10. Abstract, p.76.1994. 48. Elezovic, I., Matijevic-Aleksic, N., Boskovic, D., Colovic, M., Mijovic, A.S., Tomin, D., Mijovic, A.M., Suvajdic, N., Vidovic, A., Rolovic, Z. Disorders of hemostasis in acute leukemia. 1st Yugoslav Hematology Congress, Belgrade, Yugoslavia, October 1994. Bilten Hematol 22:86, 1994. 49. Elezovic, I., Matijevic-Aleksic, N.,Colovic, M.,. Boskovic, D., Mijovic, A.S., Tomin, D., A.M. Mijovic, Suvajdic, N., Maric, A., Rolovic, Z. Disseminated intravascular coagulation in acute leukemia. 1st Yugoslav Hematology Congress, Belgrade, Yugoslavia, October 1994. Bilten Hematol 22:87.1994. 50. Matijevic-Aleksic, N., Ghaddar, H., McPhedran, P., Wu, K.K. Bleeding disorder due to platelet cyclooxygenase-1 (COX-1) deficiency. 36th Annual Meeting, American Society of Hematology, Decembar 2-6, 1994, Nashville, TN. Blood. 84:suppl.1. 1267.1994. 51. Elezovic, I., Matijevic-Aleksic, N -1 proteinase inhibitor complexes in acute leukemia. XV Congress of the International Society on Thrombosis and Nena Matijevic, PhD Page 10 Haemostasis, Jerusalem, Israel, June 11-16, 1995. Thromb Haemost 73:1146. 1995. 52. Matei, M.C., Aleksic, N., Ahn, C., Wu, K.K., Juneja, H.S. Hemostasis activation markers in sickle cell disease: association with painful crisis. 38th Annual American Society of Hematology Meeting, Orlando, Florida, December 6-10, 1996. Blood. 88: suppl 1;2803. 53. Elezovic, I., Pilic, Z., Nedeljkovic, N., Marisavljevic, D., Matijevic-Aleksic, N., Miljic, P., Radosevic, N., and Todorovic-Tirnanic, M.: Caesare section in a case with Bernard-Suilier syndrome. X Yugoslav Hematology Days with International Participation, Niska Banja, October 10-12, 1996. Abstract Book. 122. 1996. 54. Elezovic I, Matijevic-Aleksic N, Rolovic Z: The role of elastase in coagulation disorders of acute leukemia patients. X Yugoslav Hematology Days with International Participation, Niska Banja, October 10-12, 1996. Abstract Book. 125.1996. 55. Ghaddar, H.M., Aleksic, N., Hearne, L.B., Folsom, A.R., Chambless, L.E., Morrissey, J.H., Wu, K.K. The ARIC postprandial study: relation of factor VII with factor VII gene polymorphism and triglyceride levels in carotid atherosclerosis cases and controls. XVIth Congress of the International Society on Thrombosis and Haemostasis, Florence, June 6-12, 1997. Thromb Haemost Suppl, 413.1997. 56. Folsom, A.R., Rosamond, W.D., Shahar, E., Cooper, L.S., Aleksic, N., Nieto, F.J., Rasmussen, M., Wu, K.K. Prospective study of markers of hemostatic function, inflammation, and endothelial function with risk of ischemic stroke. Abstract 1072. 71st Scientific Session of the American Heart Association, November 8-11, 1998, Dallas, Texas. Circulation, Suppl I, 98:17:207.1998. 57. Salomaa, V., Matei, V., Aleksic, N., Sansores-Garcia, L., Folsom, A.R., Juneja, H., Chambless, L.E., Wu, K.K. Soluble thrombomodulin as a predictor of incident coronary heart disease: The ARIC study. Abstract 2756. 71st Scientific Session of the American Heart Association, November 8-11, 1998, Dallas, Texas. Circulation. Suppl I, 98:17:524. 1998. 58. Aleksic, N., Juneja, H., Folsom, A.R., Ahn, C., Boerwinkle, E., Chambless, W., Wu, K.K. Prospective study of platelet PlA1/A2 polymorphism, platelet activation and incidence of coronary heart disease. The 40th American Society of Hematology Annual Meeting, Miami Beach, Florida, December 4-8, 1998. Blood 92 (suppl 1): 304a, 1998 59. Wu KK, Aleksic N, Ahn C, Boerwinkle E, Folsom A, Juneja H. Association of thrombomodulin 455A/V dimorphism with risk of developing coronary heart disease. XVIIth Congress of the International Society on Thrombosis and Haemostasis, Washington DC, Aug 14-21 1999. Thromb Haemost Suppl. 538.1999. 60. Aleksic N, Ahn C, Boerwinkle E, Juneja H, Folsom AR, Wu KK. Factor XIII V34L polymorphism and the risk for development of coronary heart disease. XVIIth Congress of the International Society on Thrombosis and Haemostasis, Washington DC, Aug 14-21 1999. Thromb Haemost Suppl. 538.1999. Nena Matijevic, PhD Page 11 61. Afshar-Kharghan V, Aleksic N, Ahn C, Boerwinkle E, Wu KK, Lopez JA. Prospective study of the association of the variable number of tandem repeats (VNTR) polymorphism in the International Society on Thrombosis and Haemostasis, Washington DC, Aug 14-21 1999. Thromb Haemost Suppl. 538.1999. 62. Wu KK, Matijevic-Aleksic N, Ahn C, Boerwinkle E, Folsom AR, Juneja H. Thrombomodulin 455A/V dimorphism is a risk factor for developing coronary heart disease in African Americans but not in Caucasians: The ARIC Study. The 41th American Society of Hematology Annual Meeting, New Orleans, Louisiana, December 3-7, 1999. Blood. 94:374.suppl.1.1999. 63. Folsom AR, Aleksic N, Salomaa V, Park E, Juneja H, Wu KK. Fibrinolytic variables and incident CHD in the Atherosclerosis Risk in Communities (ARIC) Study. 40th Annual Conference on Cardiovascular Disease Epidemiology and Prevention, San Diego, CA, March 1-4, 2000.Circulation. 101:721. 2000. 64. Elezovic I, Matijevic-Aleksic N, Rolovic Z, Boskovic D, Colovic M. Hypercoagulability in patients with acute leukemia prior to therapy. 28th Congress of the International Society of Hematology, Aug 26-30, Toronto, Canada. Abstracts. 2000. 65. Aleksic N, Ahn C, Juneja H, Boerwinkle E, Ballantyne CM, Wu KK. Effect of interaction of plasma soluble thrombomodulin (sTM) and soluble intercellular adhesion molecule-1 (sICAM-1) on predicting risk of incident coronary heart disease (CHD): The ARIC Study. The 42nd American Society of Hematology Meeting, San Francisco, CA, December 1-5, 2000. Blood. 96:11:816a.2000. 66. Tumbusch KJ, Goldsby J, Arbab F, Matijevic-Aleksic N, Huang J-C. The expression of prostaglandin H synthase-2 and the profile of arachidonic acid metabolism by human fallopian tubes. 7th Annual Texas Forum of Female Reproduction, May 3-4, 2001, Houston, TX. 67. Tumbusch KJ, Goldsby J, Arbab F, Matijevic-Aleksic N, Huang J-C. The expression of prostaglandin H synthase-2 and the profile of arachidonic acid metabolism by human fallopian tubes (P-466). 57th Annual Meeting of the American Society for Reproductive Medicine, Orlando, FL, October 20-25, 2001. Fertil Steril. 76 (3S-suppl):S267-268 68. Aleksic N, Ahn C, Juneja H, Boerwinkle E, Ballantyne C, Wu KK. Effect of interaction of plasma soluble thrombomodulin (sTM) and soluble intercellular adhesion molecule-1 (sICAM-1) on predicting risk of incident coronary heart disease (CHD): The ARIC Study. XVIII Congress of the International Society on Thrombosis and Hemostasis, Paris, France, July 6-12, 2001. Thromb Haemost Suppl.2001. 69. Aleksic N, Folsom AR, Cushman M, Heckbert SR, Tsai M, Wu KK. Soluble plasma thrombomodulin (sTM), TM genotype, and risk of venous thromboembolism: The Nena Matijevic, PhD Page 12 Longitudinal Investigation of Thromboembolism Etiology (LITE) Study. XVIII Congress of the International Society on Thrombosis and Hemostasis, Paris, France, July 6-12, 2001. Thromb Haemost Suppl. 2001 70. Folsom AR, Cushman M, Tsai MY, Aleksic N, Heckbert SR, Boland LL, Tsai AW, Yanez ND, Rosamond WD. Prospective study of venous thromboembolism in relation to factor V Leiden and related factors: The Longitudinal Investigation of Thromboembolism Etiology (LITE) Study. XVIII Congress of the International Society on Thrombosis and Hemostasis, Paris, France, July 6-12, 2001. Thromb Haemost Suppl. 2001. 71. Tsai A, Cushman M, Tracy RP, Heckbert SR, McGovern P, Aleksic N, Rosamond WD, Folsom AR. A prospective study of factor VIIIc and von Willebrand factor in relation to venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE) Study. XVIII Congress of the International Society on Thrombosis and Hemostasis, Paris, France, July 6-12, 2001. Thromb Haemost Suppl.2001 72. Cushman M, Folsom AR, Wang L, Heckbert SR, White R, Aleksic N, Tsai MY, Tracy RP. Concentration of Thrombin Activable Fibrinolysis Inhibitor (TAFI), a polymorphism of the TAFI gene, and the risk of venous thrombosis in a prospective study: The Longitudinal Investigation of Thromboembolism Etiology (LITE) Study. XVIII Congress of the International Society on Thrombosis and Hemostasis, Paris, France, July 6-12, 2001. Thromb Haemost Suppl. 2001 73. Cushman M, Folsom AR, Aleksic N, Rosamond WD, Tracy RP, Heckbert SR. Fibrin fragment D-dimer and the risk of future venous thrombosis. American Society of Hematology, 43rd Annual Meeting, December 7-11, 2001, Orlando, Florida. Blood. 98:11:755a. 2001. 74. Wu KK, Matijevic-Aleksic N, Ahn C, Juneja H, Wang Y-W. A positive interaction between plasma thrombomodulin and fibrinogen or factor VIII in predicting incident coronary heart disease. American Society of Hematology, 43rd Annual Meeting, December 7-11, 2001, Orlando, Florida. Blood. 98:11:790a. 2001. 75. Matijevic-Aleksic N, Ahn C, Wang W, Juneja H, Wu KK. Differential association of thrombomodulin A455V polymorphism with risk of incident coronary heart disease (CHD) and ischemic stroke: The ARIC study. American Society of Hematology, 43rd Annual Meeting, December 7-11, 2001, Orlando, Florida. Blood. 98:11:790a. 2001. 76. Huang J-C, Wun W-S A, Goldsby JS, Matijevic-Aleksic N, Wu KK. Prostacyclin enhances embryo hatching. 57th Annual Meeting of the American Society for Reproductive Medicine, Abstracts. 2002. 77. Matijevic-Aleksic N, Ahn C, Afshar-Kharghan V, Sweetman R, Lopez JA, Nugent DJ, Boerwinkle E, Wu KK. Coexistence of multiple hemostatic genetic risk factors does not increase risk of coronary heart disease. XIXth Congress of the International Society on Nena Matijevic, PhD Page 13 Thrombosis and Hemostasis, Birmingham, UK, July 12-18. J Thromb Haemost. 1: Suppl 1. OS239. 2003. 78. Matijevic N, Radovancevic R, Bracey A, Radovancevic B, Gregoric I, Frazier O. Platelet and monocyte activation in patients undergoing circulatory support with left ventricular assist devices (LVAD). XXIst Congress of the International Society on Thrombosis and Haemostasis, Geneva, Switzerland, July 6-12 2007, J Thromb Haemost 2007; 5, Suppl 2; PW-369. 79. Matijevic N, Bracey AW, Radovancevic B, Radovancevic R, Gregoric ID, Frazier OH. Increased leukocyte-platelet interactions associated with high risk heart surgery. 12th Congress of the European Hematology Association, Vienna 9 June 2007, Book of abstracts: 1596. 80. Bracey AW, Radovancevic R, Matijevic N, Radovancevic B, Carranza S, Gregoric I, Frazier OH. Transfusion rates and platelet activation in patients undergoing high risk cardiac surgery. 12th Congress of the European Hematology Association, Vienna 9 June 2007, Book of abstracts. 81. Radovancevic R, Radovancevic B, Bracey A, Matijevic N, Carranza S, Gregoric I, Frazier OH. Effect of platelet activation on bleeding and transfusion rates in patients undergoing high risk cardiac surgery. Vox Sang 2007: 93 (Suppl 1):S12-3. 82. Matijevic N, Catellier D, Wu KK, Heiss G, Folsom AR. Association of monocyte and platelet markers with peripheral arterial disease: ARIC Carotid MRI Study. 48th Cardiovascular Disease Epidemiology and Prevention Annual Conference, Colorado Springs, CO, March 11-15, 2008. Circulation Vol 117, No 11 March 18, 2008, Abstract p200, page e252 83. Yamagishi K, Aleksic N, Hannan P, Juneja H, Folsom AR. Coagulation factors II, V, IX, X, XI, XII, plasminogen and α-2 antiplasmin and risk of coronary heart disease: a case-cohort study in ARIC. 48th Cardiovascular Disease Epidemiology and Prevention Annual Conference, Colorado Springs, CO, March 11-15, 2008. Circulation Vol 117, No 11 March 18, 2008. 84. Aleksic N, Catellier D, Wu KK, Heiss G, Folsom AR. Monocyte and platelet markers in peripheral arterial disease (PAD): ARIC Carotid MRI study. 20th International Congress on Thrombosis, Athens, Greece, June 25-28, 2008. Pathophysiol Haemost Thromb 36 (suppl 1) (2007-08), p068, A41. 85. Matijevic N, Wang W, Pati S, Kozar R, Conyers J, and Holcomb JB. Phenotypic assessment of cellular microparticles in fresh frozen plasma during storage. 32d Annual Conference on Shock, San Antonio, TX. June 6-9, 2009. 86. Holcomb J, Gerber M, Kozar R, Parthasarthy R, Matijevic N, Doursout MF, Ko T, Hartwell B, Conyers J and Pati S. Protective effects of plasma (FFP) on pulmonary and Nena Matijevic, PhD Page 14 lymphatic endothelial permeability diminish between day 0 through day 5 after thaw. 32nd Annual Conference on Shock, San Antonio, TX. June 6-9, 2009. 87. Doursout MF, Liang YY, Pati S, Matijevic N, Uray K, Holcomb JB: Role of the NF-кB pathway in rats subjected to moderate hemorrhage, FASEB J April 22, 2009 23:LB3802009. 88. Matijevic N, Dong JF, Hartwell E, Pati S, Holcomb JB. The protective effects of fresh thawed plasma (FFP) on endothelial permeability are correlated with changes in thrombospondin-1 microparticles. XXII Congress of the ISTH, Boston July 11-16, 2009. J Thromb Haemost Vol 7, Supplement 2. PP-MO-767. 89. Matijevic N, Wu KK, Howard AG, Wasserman B, Wang W, Folsom AR, Sharrett R. Association of blood cellular markers with carotid plaque size and composition. XXII Congress of the ISTH, Boston, MA, July 11-16, 2009. J Thromb Haemost Vol 7, Supplement 2. PP-WE-819. 90. Nettleton JA, Matijevic N, Follis JL, Folsom AR, and Boerwinkle E. Dietary Patterns and Flow Cytometry-Measured Biomarkers of Inflammation and Cellular Activation. Joint Conference - 50th Cardiovascular Disease Epidemiology and Prevention - and - Nutrition, Physical Activity, and Metabolism, San Francisco, March2010 91. Kucharska-Newton A, Monda K, Campbell S, Wagenknecht L, Boerwinkle E, Wasserman B, Aleksic-Matijevic N, Heiss G. Markers of Platelet Activation and Carotid Artery Plaque Morphology: The Atherosclerosis Risk in Communities (ARIC) Study, AHA 2010 92. Kucharska-Newton AM, Monda KL, Avery CL, Aleksic-Matijevic N, Folsom AR. Longitudinal predictors of in vivo platelet activation: The Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study, AHA 2010 93. Wang W, Holcomb JB, Kostousov V, Matijevic N. Diminished hemostatic potential of thawed plasma measured by two novel assays. Shock, vol 33, suppl 1, abstract 55, p 29, 2010. 33th Annual Conference on Shock, Portland, OR, June12-15. 94. Kostousov V, Matijevic N, Holcomb JB. Deficiency of protein C inhibitor activity in liquid plasma stored at 4C for 5 days. Shock, vol 33, suppl 1, abstract 58, p 30, 2010. 33th Annual Conference on Shock, Portland, OR, June12-15. 95. Matijevic N, Wang W Y-W, Kozar R, Gonzales E, Holcomb JB. Low levels of platelet microparticles correlate with poor outcomes in shock patients. Shock, vol 33, suppl 1, abstract 106, p45, 2010. 33th Annual Conference on Shock, Portland, OR, June12-15. 96. Alrehani N, Matijevic N, Doursout MF, Dong JF, Cruz MA, Holcomb JB, Vinod V. Regulation of ptotein phosphatase 2B activity and the exocytosis of von Willebrand factor in hemorrhagic shock. Shock, vol 33, suppl 1, abstract 118, p49, 2010. 33th Annual Conference on Shock, Portland, OR, June12-15. Nena Matijevic, PhD Page 15 97. Holcomb JB, Rahbar MH, Del Junco DJ, Zhang J, Fox EE, Matijevic N, Cotton BA, Cohen MJ, Schreiber MA and the PROMMTT Investigators. Initial Report from PROMMTT: The DoD Sponsored Prospective, Observational, Multi-Center Massive Transfusion Study. Advanced Technology Applications for Combat Casualty Care (ATACCC) meeting, St Petersburg, FL, Aug 2010 98. Matijevic N, Wang Y-W W, Kostousov V, Letourneau P, and Holcomb JB. Multiple levels of degradation diminish aged plasma’s hemostatic potential. 69th Meeting of the American Association for the Surgery of trauma (AAST) 2010, Boston, MA, September 23-25. 99. Letourneau P, McManus M, Sowards K, Wang W, Pati S, Matijevic N, Wade C, Holcomb J. Aged Plasma Transfusion Increases Mortality in Rat Model of Uncontrolled Hemorrhage. Western Trauma Association (WEST), Big Sky, Montana, Feb26-March1, 2011 100. Matijevic N, Kostousov V, Wang YWW, Wade CE, Holcomb JB. Hemostatically distinct FFPs equally improve abnormal TEG variables in an in vitro dilutional coagulopathy model. 34th Annual Conference on Shock, Norfolk, VA, June11-14, 2011; Shock vol35, suppl1, 2011 101. Kostousov V, Matijevic N, Wang YWW, Holcomb JB, Cotton B, Wade CE. Hyperfibrinolytic TEG pattern in diluted blood is provoked by tissue factor. 34th Annual Conference on Shock, Norfolk, VA, June11-14, 2011; Shock vol35, suppl1, 2011 102. Pawelczyk NS, Salsbury JR, Baer L, Wang Y, Matijevic N, Letourneau PA, Holcomb JB, Wade CE. Blood loss after hemodilution and uncontrolled hemorrhage is a function of preinjury MAP and not dilutional coagulopathy. 34th Annual Conference on Shock, Norfolk, VA, June11-14, 2011; Shock vol35, suppl1, 2011. 103. Huby MP, Pawelczyk NS, Salsbury JR, Baer L, Wang Y, Matijevic N, Letourneau PA, Holcomb JB, Wade CE. Blood loss after hemodilution and uncontrolled hemorrhage is a function of pre-injury MAP and not dilutional coagulopathy. Advanced Technology Applications for Combat Casualty Care (ATACCC) meeting, Fort Lauderdale, FL, Aug 1518, 2011. 104. Matijevic N, Kostousov V, Wang Y-W W, Wade CE, Cotton BA, Holcomb JB. The prevalence of thrombogram-based APC resistant phenotypes among FFP donors. Advanced Technology Applications for Combat Casualty Care (ATACCC) meeting, Fort Lauderdale, FL, Aug 15-18, 2011. 105. Radwan ZA, Bai Y, Matijevic N, del Junco DJ, McCarthy JJ, Wade CE, Holcomb JB, Cotton BA. An emergency department thawed plasma protocol decreases blood component utilization and improves survival in severely injured patients. Advanced Technology Applications for Combat Casualty Care (ATACCC) meeting, Fort Lauderdale, FL, Aug 1518, 2011. Nena Matijevic, PhD Page 16 106. Holcomb JB and the PROMMTT study investigators: Initial report from PROMMTT: The Prospective, Observational, Multi-Center Massive Transfusion Study. Advanced Technology Applications for Combat Casualty Care (ATACCC) meeting, Fort Lauderdale, FL, Aug 15-18, 2011. 107. Wade C, Holcomb JB, Eastridge BJ, Jones J, Del Junco DJ, Rahbar MH and the PROMMTT investigators. In-hospital mortality of civilian and military casualties receiving a blood transfusion. Advanced Technology Applications for Combat Casualty Care (ATACCC) meeting, Fort Lauderdale, FL, Aug 15-18, 2011. 108. Matijevic N, Kostousov V, Wang Y-W W, Wade CE, Cotton BA, Holcomb JB. The prevalence of thrombogram-based APC resistant phenotypes among FFP donors. 70th Annual Meeting of the American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery, Chicago, IL, September 14-17, 2011. 109. Cotton BA, Radwan ZA, Matijevic N, Pivalizza E, Podbielski J, Kozar RA, Wade CE, Holcomb JB. Admission rapid thromboelastography (rTEG) predicts development of pulmonary embolism in trauma patients. 70th Annual Meeting of the American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery, Chicago, IL, September 14-17, 2011. 110. Radwan ZA, Bai Y, Matijevic N, del Junco DJ, McCarthy JJ, Wade CE, Holcomb JB, Cotton BA. An emergency department thawed plasma protocol decreases blood component utilization and improves survival in severely injured patients. 70th Annual Meeting of the American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery, Chicago, IL, September 14-17, 2011. 111. Matijevic N, Kostousov V, Wang Y-WW, Hartwell E, Holcomb JB. Higher Hemostatic Potential in the Presence of the Activated Protein C in FP24 Compared to FFP, Annual Meeting of the American Association of Blood Banks (AABB), October 22-25, 2011, San Diego, CA. 112. Sixta S, Hatch Q, Matijevic N, Wade CE, Holcomb JB, Cotton B. Mechanistic Determinants of the Acute Coagulopathy of Trauma (ACoT) in Patients undergoing Emergent laparotomy. 53rd Annual Meeting of the American Society of Hematology, December 10-13, 2011, San Diego, CA, Blood 2011;118:3319. 113. Cotton BA, Matijevic N, Minei K, Kostousov V, Radwan ZA, Pivalizza E, Wade CE, Holcomb JB. Hyperfibrinolysis on admission is an uncommon but highly lethal event associated with shock and prehospital crystalloid administration. 25th Annual Scientific Assembly, Eastern Association for the Surgery of Trauma (EAST), January 10-14, 2012, Lake Buena Vista, FL. 114. Matijevic, N., Kostousov, V., Wang, Y-W.W., Wade, C.E., Holcomb, J.B., and Cotton, B.A.: Low dose of tranexamic acid reverses hyperfibrinolytic TEG in an in vitro traumatic Nena Matijevic, PhD Page 17 coagulopathy model. 7th Congress of the International Federation of Shock Societies and 35th Annual Congress on Shock, Jun 9-13, 2012, Miami Beach, FL. 115. Matijevic, N., Wang, Y-W., Cotton, B.A., Hartwell, E., Barbeau, J., and Holcomb, J.B.: Superior hemostatic profiles of never frozen liquid plasma (LQP) compared to thawed fresh frozen plasma (TP). Annual Meeting of the American Association for Surgery of Trauma and Clinical Congress of Acute Care Surgery (AAST), September 9-12, 2012, Kauai, HI. 116. Matijevic, N., Wang, Y-W., Holcomb, .JB., Cotton, B.A., Wade, C.E., Schreiber, M.A., Muskat, P., Myers, J.G., and Cohen, M.J., on behalf of the PROMMTT study group: Cellular profiles following major trauma: the PROMMTT study. PROMMTT Symposium, September 11, 2012, Kauai, HI. 117. Cohen, M.J., Kutcher, M., Redick, B., Nelson, M., Call, M., Knudson, M, Schreiber, M.A., Bulger, E.M., Muskat, P., Alarcon, L.H., Myers, J.G., Rahbar, M.H., Brasel, K.J., Phelan, H.A., del Junco, D.J., Fox, E.E, Wade, C.E., Holcomb, J.B, Cotton, B.A., and Matijevic, N., on behalf of the PROMMTT study group.: Clinical and mechanistic drivers of acute traumatic coagulopathy. PROMMTT Symposium, September 11, 2012, Kauai, HI. 118. Fox EE, Bulger EM, Dickerson AS, del Junco DJ, Klotz P, Podbielski J, Matijevic N, Brasel KJ, Holcomb JB, Schreiber MA, Cotton BA, Phelan HA, Cohen MJ, Myers JG, Alarcon LH, Muskat P, Wade CE, Rahbar MH, on behalf of the PROMMTT Study Group. Waiver of consent in non-interventional, observational emergency research: the PROMMTT experience. PROMMTT Symposium, September 11, 2012, Kauai, HI. 119. Matijevic, N., Wang, W., Hartwell, E., Cotton, B., Wade, C.E., Barbeau, J., and Holcomb, J.B.: Clotting properties of never frozen liquid plasma during 26 days of cold storage. Annual Meeting of the American Association of Blood Banks (AABB), October 6-9, 2012, Boston, MA. 120. Goodman MD, Farley DL, Cardenas JC, Pommerening M Podbielski J, Matijevic N, Wade CE, Holcomb JB, Cotton BA. Thrombelastography velocity curve values more accurately predict clinically significant fibrinolysis. Surgical Forum of the American College of Surgeon’s 99th Clinical Congress, Washington, D.C., 2013. 121. CardenasJ, Wang W, Baer L, Matijevic N, Cotton BA, Holcomb JB, Wade CE. Autologous Cleavage of the GPIbα Receptor Promotes Platelet Dysfunction Following Trauma. Thrombosis and Hemostasis Summit of North America, Chicago, IL, April 2013. 122. Matijevic, N., Wang, Y-W., Holcomb, J.B., Cotton, B.A., Wade, C.E., Schreiber, M.A., Muskat, P., Myers, J.G., and Cohen, M.J., on behalf of the PROMMTT study group.: Circulating microparticles and thrombin generation phenotypes in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study: correlation with coagulopathy and survival. XXIV Congress of the ISTH, June 29-July 04, 2013, Amsterdam, Netherlands. Nena Matijevic, PhD Page 18 123. Cardenas, J., Matijevic, N., Cotton, B., Holcomb, J., and Wade, C.: Contribution of the plasminogen activation system during hyperfibrinolysis in trauma-induced coagulopathy. XXIV Congress of the ISTH, June 29-July 04, 2013, Amsterdam, Netherlands. 124. Cardenas, J.C, Wang, Y-W., Baer, L.A., Matijevic, N., Cotton, B.A., Holcomb, J.B., and Wade, C.E.: Autologous Cleavage of the GPIbα Receptor Promotes Platelet Dysfunction Following Trauma. The American Heart Association Resuscitation Science Symposium, Dallas, TX, November, 2013. 125. Dua, A, Cao Y, Matijevic N, Wang Y-W, Pati S, Wade CE, Ko TC, Holcomb JB. Never frozen liquid plasma blocks endothelial permeability as effectively as thawed fresh frozen plasma. 27th Annuall Scientific Assembly of The Eastern Association for Surgery of Trauma (EAST), Naples, FL, Jan 2014. 126. Cardenas, J.C., Baer, L.A., Matijevic, N., Cotton, B.A., Holcomb, J.B., and Wade, C.E.: Measuring thrombin generation as a tool for predicting hemostatic potential and transfusion requirements following trauma. The Western Trauma Association, Steamboat Springs, CO, March, 2014. 127. Cardenas, J.C., Wang, Y-W., Baer, L.A., Matijevic, N., Cotton, B.A., Holcomb, J.B., and Wade, C.E.: Role of GPIbα Receptor Shedding in Platelet Dysfunction Following Trauma. The 7th Symposium on Hemostasis, Chapel Hill, NC, May, 2014. B. REFEREED ORIGINAL ARTICLES IN JOURNALS 1. 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Volcik, K.A., Catellier, D., Folsom, A.R., Matijevic, N., Wasserman, B., and Boerwinkle, E.: SELP and SELPLG Genetic Variation is Associated with Cell Surface Measures of PSEL and PSGL-1: The Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study. Clin. Chem. 55:1076-82, 2009. PMID: 19395438. 48. Radovancevic, R., Matijevic, N., Bracey, A.W., Radovancevic, B., Elayda, M.A., Gregoric, I.D., and Frazier, O.H.: Increased Monocyte Activation and Leukocyte-Platelet Interactions during Circulatory Support with Left Ventricular Assist Devices. ASAIO J. 55:459-64, 2009. PMID: 19730003. 49. Gottesman, R.F., Cummiskey, C., Chambless, L., Wu, K.K., Aleksic, N., Folsom, A.R., and Sharrett, A.R.: Hemostatic factors and subclinical brain infarction in a community-based sample: The ARIC study. Cerebrovasc. Dis. 28:589-594, 2009. PMID: 19844099. PMCID: 2914353. 50. 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Matijevic, N., Kostousov, V., Wang, Y-W.W., Wade, C.E., Wang, W., Letourneau, P., Hartwell, E., Kozar, R., Ko, T., and Holcomb, J.B.: Multiple levels of degradation diminish hemostatic potential of thawed plasma. J. Trauma. 70:71-80, 2011. PMID: 21217484. 60. Matijevic, N., Wu, K.K., Nidkarni, N., Heiss, G., and Folsom, A.R.: The ARIC Carotid MRI study of blood cellular markers: an inverse association of monocyte myeloperoxidase content with peripheral arterial disease. Angiology. 62:237-44, 2011. PMID: 21487219. 61. Matijevic, N., Wu, K.K., Howard, A.G., Wasserman, B., Wang, W.Y-W., Folsom, A.R., and Sharrett, A.R.: Association of blood monocyte and platelet markers with carotid artery characteristics The Atherosclerosis Risk in Communities Carotid MRI Study. Cerebrovasc. Dis. 31:552-558, 2011. PMID: 21487219. Nena Matijevic, PhD Page 25 62. Bielinski, S.J., Hall, J.L., Pankow, J.S., Boerwinkle, E., Matijevic-Aleksic, N., He, M., Chambless, L., and Folsom, A.R.: Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: the Atherosclerosis Risk in Communities MRI Study. Hum. Genet. 129:655-62, 2011. PMID: 21298466. 63. Holcomb J.B., Zarzabal, L.A., Michalek, J.E., Kozar, R.A., Spinella, P.C., Perkins, J.G., Matijevic, N., Dong, J-F., Pati, S., Wade, C.E.; Trauma Outcomes Group, Holcomb, J.B., Wade, C.E., Cotton, B.A., Kozar, R.A., Brasel, K.J., Vercruysse, G.A., MacLeod, J.B., Dutton, R.P., Hess, J.R., Duchesne, J.C., McSwain, N.E., Muskat, P.C., Johannigamn, J.A., Cryer, H.M., Tillou, A., Cohen, M.J., Pittet, J.F., Knudson, P., DeMoya, M.A., Schreiber, M.A., Tieu, B.H., Brundage, S.I., Napolitano, L.M., Brunsvold, M.E., Sihler, K.C., Beilman, G.J., Peitzman, A.B., Zenati, M.S., Sperry, J.L., Alarcon, L.H., Croce, M.A., Minei, J.P., Steward, R.M., Cohn, S.M., Michalek, J.E., Bulger, E.M., Nunez, T.C., Ivatury, R.R., Meredith, J.W., Miller, P.R., Pomper, G.J., and Marin, B.: Increased platelet:RBC ratios are associated with improved survival after massive transfusion. J. Trauma. 71(2 Suppl 3):S31828, 2011. PMID: 21814099. 64. Letourneau, P.A., McManus, M., Sowards, K., Wang, W., Wang, Y-W., Matijevic, N., Pati, S., Wade, C.E., and Holcomb, J.B.: Aged plasma transfusion increases mortality in a rat model of uncontrolled hemorrhage. J. Trauma. 71:1115-9, 2011. PMID: 22071917. 65. Rahbar, M.H., Fox, E.E., Del Junco, D.J., Cotton, B.A., Podbielski, J.M., Matijevic, N., Cohen, M.J., Schreiber, M.A., Zhang, J., Mirhaji, P., Duran, S., Reynolds, R.J., BenjaminGarner, R., and Holcomb, J.B.: The PROMMTT Investigators. Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study. Resuscitation. 83:459-64, 2012. PMID: 22001613. 66. Kostousov, V., Wang, Y-W.W., Wade, C.E., Holcomb, J.B., Cotton, B.A., and Matijevic, N.: Hemostatically distinct FFPs equally improve abnormal TEG variables in an in vitro dilutional coagulopathy model. Thromb Res. 130:429-34, 2012. PMID: 22386721. 67. Cotton, B.A., Minei, K.M., Radwan, Z.A., Matijevic, N., Pivalizza, E., Podbielski, J., Wade, C.E., Kozar, R.A., and Holcomb, J.B.: Admission rapid thromboelastography predicts development of pulmonary embolism in trauma patients. J Trauma Acute Care Surg. 72:1470-5, discussion 1475-7, 2012. PMID: 22695409. 68. Cotton, B.A., Harvin, J.A., Kostousov, V., Minei, K.M., Radwan, Z.A., Schöchl, H., Wade, C.E., Holcomb, J.B., and Matijevic, N.: Hyperfibrinolysis on admission is an uncommon but highly lethal event associated with shock and pre-hospital fluid administration. J Trauma Acute Care Surg. 73:365-70, discussion 370, 2012. PMID: 22846941. 69. Tang, W., Schwienbacher, C., Lopez, L.M., Ben-Shlomo, Y., Oudot-Mellakh, T., Johnson, A.D., Samani, N.J., Basu, S., Gögele, M., Davies, G., Lowe, G.D., Tregouet, D.A., Tan, A., Pankow, J.S., Tenesa, A., Levy, D., Volpato, C.B., Rumley, A., Gow, A.J., Minelli, C., Yarnell, J.W., Porteous, D.J., Starr, J.M., Gallacher, J., Boerwinkle, E., Visscher, P.M., Nena Matijevic, PhD Page 26 Pramstaller, P.P., Cushman, M., Emilsson, V., Plump, A.S., Matijevic, N., Morange, P.E., Deary, I.J., Hicks, A.A., and Folsom, A.R.: Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease. Am J Hum Genet. 91:152-62, 2012. PMID: 22703881. 70. Sixta, S., Hatch, Q., Matijevic, N., Wade, C.E., Holcomb, J.B., and Cotton, B.A.: Mechanistic determinates of the acute coagulopathy of trauma (ACoT) in patients requiring emergent laparotomy. Intl J Burns Trauma. 2:158-66, 2012. PMID: 23272297. 71. 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PROMMTT Study Group: Defining when to initiate massive transfusion: a validation study of individual massive transfusion triggers in PROMMTT patients. J Trauma Acute Care Surg. 74:59-65, 67-8; discussion 667. 2013. PMID: 23271078. 74. Matijevic, N., Wang, Y.W., Cotton, B.A., Hartwell, E., Barbeau, J.M., Wade, C.E., and Holcomb, J.B.: Better hemostatic profiles of never-frozen liquid plasma compared with thawed fresh frozen plasma. J Trauma Acute Care Surg. 74:84-90, 2013. PMID: 23271081. discussion 90-1. Erratum in: J Trauma Acute Care Surg. 2013, 74:1182. 75. Kostousov, V., Wang, Y-W., Cotton, B.A., Wade, C.E., Holcomb, J.B., and Matijevic, N.: Nena Matijevic, PhD Page 27 Influence of resuscitation fluids, fresh frozen plasma and antifibrinolytics on fibrinolysis in a thrombelastography-based, in-vitro, whole-blood model. Blood Coagul Fibrinolysis. 24:48997, 2013. PMID: 23406662. 76. Radwan, Z.A., Matijevic, N., Podbielski, J., Del Junco, D., McCarthy, J.J., Bai, Y., Wade, C.E., Holcomb, J.B., and Cotton, B.A.: An Emergency Department Thawed Plasma Protocol for Severely Injured Patients. JAMA Surg.148:170-175, 2013. PMID: 23426594. 77. Holcomb, J.B., del Junco, D.J., Fox, E.E., Wade, C.E., Cohen, M.J., Schreiber, M.A., Alarcon, L.H., Bai, Y., Brasel, K.J., Bulger, E.M., Cotton, B.A., Matijevic, N., Muskat, P., Myers, J.G., Phelan, H.A., White, C.E., Zhang, J., and Rahbar, M.H. PROMMTT Study Group: The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks. JAMA Surg. 148:127-36, 2013. PMID: 23560283. 78. Pawelczyk, N.S., Huby, M.P., Salsbury, J.S., Baer, L.A., Wang, Y-W.W., Matijevic, N., Holcomb, J.B., and Wade, C.E.: Association of hemodilution and blood pressure in uncontrolled bleeding. J Surg Res.184:959-65, 2013. PMID:23608619. 79. Wade CE, del Junco DJ, Fox EE, Cotton BA, Cohen MJ, Muskat P, Schreiber MA, Rahbar MH, Sauer RM, Brasel KJ, Bulger EM, Myers JG, Phelan HA, Alarcon LH, Holcomb JB; PROMMTT Study Group. Do-not-resuscitate orders in trauma patients may bias mortalitybased effect estimates: an evaluation using the PROMMTT study. J Trauma Acute Care Surg.;75(1 Suppl 1):S89-96, 2013. PMID:23778517. 80. Rahbar MH, del Junco DJ, Huang H, Ning J, Fox EE, Zhang X, Schreiber MA, Brasel KJ, Bulger EM, Wade CE, Cotton BA, Phelan HA, Cohen MJ, Myers JG, Alarcon LH, Muskat P, Holcomb JB; PROMMTT Study Group. A latent class model for defining severe hemorrhage: experience from the PROMMTT study. J Trauma Acute Care Surg. 75(1 Suppl 1):S82-8, 2013. PMID:23778516. 81. Fuchs PA, del Junco DJ, Fox EE, Holcomb JB, Rahbar MH, Wade CA, Alarcon LH, Brasel KJ, Bulger EM, Cohen MJ, Myers JG, Muskat P, Phelan HA, Schreiber MA, Cotton BA; PROMMTT Study Group. Purposeful variable selection and stratification to impute missing Focused Assessment with Sonography for Trauma data in trauma research. J Trauma Acute Care Surg. 75(1 Suppl 1):S75-81, 2013. PMID:23778515. 82. Trickey AW, Fox EE, del Junco DJ, Ning J, Holcomb JB, Brasel KJ, Cohen MJ, Schreiber MA, Bulger EM, Phelan HA, Alarcon LH, Myers JG, Muskat P, Cotton BA, Wade CE, Rahbar MH; PROMMTT Study Group. The impact of missing trauma data on predicting massive transfusion. J Trauma Acute Care Surg. 75(1 Suppl 1):S68-74, 2013. PMID: 23778514. 83. Robinson BR, Cotton BA, Pritts TA, Branson R, Holcomb JB, Muskat P, Fox EE, Wade CE, del Junco DJ, Bulger EM, Cohen MJ, Schreiber MA, Myers JG, Brasel KJ, Phelan HA, Alarcon LH, Rahbar MH, Callcut RA; PROMMTT study group. Application of the Berlin Nena Matijevic, PhD Page 28 definition in PROMMTT patients: the impact of resuscitation on the incidence of hypoxemia J Trauma Acute Care Surg. 75(1 Suppl 1):S61-7, 2013. PMID:23778513. 84. Hubbard A, Munoz ID, Decker A, Holcomb JB, Schreiber MA, Bulger EM, Brasel KJ, Fox EE, del Junco DJ, Wade CE, Rahbar MH, Cotton BA, Phelan HA, Myers JG, Alarcon LH, Muskat P, Cohen MJ; PROMMTT Study Group. Time-dependent prediction and evaluation of variable importance using superlearning in high-dimensional clinical data. J Trauma Acute Care Surg. 75(1 Suppl 1):S53-60, 2013. PMID:23778512. 85. Barbosa RR, Rowell SE, Fox EE, Holcomb JB, Bulger EM, Phelan HA, Alarcon LH, Myers JG, Brasel KJ, Muskat P, del Junco DJ, Cotton BA, Wade CE, Rahbar MH, Cohen MJ, Schreiber MA; PROMMTT Study Group. Increasing time to operation is associated with decreased survival in patients with a positive FAST examination requiring emergent laparotomy. J Trauma Acute Care Surg. 75(1 Suppl 1):S48-52, 2013. PMID:23778511. 86. Cohen MJ, Kutcher M, Redick B, Nelson M, Call M, Knudson MM, Schreiber MA, Bulger EM, Muskat P, Alarcon LH, Myers JG, Rahbar MH, Brasel KJ, Phelan HA, del Junco DJ, Fox EE, Wade CE, Holcomb JB, Cotton BA, Matijevic N; PROMMTT Study Group. Clinical and mechanistic drivers of acute traumatic coagulopathy. J Trauma Acute Care Surg. 75(1 Suppl 1):S40-7, 2013. PMID:23778510. 87. Holcomb JB, Fox EE, Zhang X, White N, Wade CE, Cotton BA, del Junco DJ, Bulger EM, Cohen MJ, Schreiber MA, Myers JG, Brasel KJ, Phelan HA, Alarcon LH, Muskat P, Rahbar MH; PROMMTT Study Group. Cryoprecipitate use in the PROMMTT study. J Trauma Acute Care Surg. 75(1 Suppl 1):S31-9, 2013. PMID:23778509. 88. del Junco DJ, Holcomb JB, Fox EE, Brasel KJ, Phelan HA, Bulger EM, Schreiber MA, Muskat P, Alarcon LH, Cohen MJ, Cotton BA, Wade CE, Myers JG, Rahbar MH; PROMMTT Study Group. Resuscitate early with plasma and platelets or balance blood products gradually: findings from the PROMMTT study. J Trauma Acute Care Surg. 75(1 Suppl 1):S24-30, 2013. PMID:23778507. 89. Rahbar E, Fox EE, del Junco DJ, Harvin JA, Holcomb JB, Wade CE, Schreiber MA, Rahbar MH, Bulger EM, Phelan HA, Brasel KJ, Alarcon LH, Myers JG, Cohen MJ, Muskat P, Cotton BA; PROMMTT Study Group. Early resuscitation intensity as a surrogate for bleeding severity and early mortality in the PROMMTT study. J Trauma Acute Care Surg. 75(1 Suppl 1):S16-23, 2013. PMID:23778506. 90. Hampton DA, Fabricant LJ, Differding J, Diggs B, Underwood S, De La Cruz D, Holcomb JB, Brasel KJ, Cohen MJ, Fox EE, Alarcon LH, Rahbar MH, Phelan HA, Bulger EM, Muskat P, Myers JG, del Junco DJ, Wade CE, Cotton BA, Schreiber MA; PROMMTT Study Group. Prehospital intravenous fluid is associated with increased survival in trauma patients. J Trauma Acute Care Surg. 75(1 Suppl 1):S9-15, 2013. PMID:23778518. 91. Fox EE, Bulger EM, Dickerson AS, del Junco DJ, Klotz P, Podbielski J, Matijevic N, Brasel KJ, Holcomb JB, Schreiber MA, Cotton BA, Phelan HA, Cohen MJ, Myers JG, Nena Matijevic, PhD Page 29 Alarcon LH, Muskat P, Wade CE, Rahbar MH; PROMMTT Study Group. Waiver of consent in noninterventional, observational emergency research: the PROMMTT experience. J Trauma Acute Care Surg. 75(1 Suppl 1):S3-8, 2013. PMID:23778508. 92. del Junco DJ, Fox EE, Camp EA, Rahbar MH, Holcomb JB; PROMMTT Study Group. Seven deadly sins in trauma outcomes research: an epidemiologic post mortem for major causes of bias. J Trauma Acute Care Surg. 75(1 Suppl 1):S97-103, 2013. PMID:23778519. 93. Holcomb JB, Fox EE, Wade CE; PROMMTT Study Group. The PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study. J Trauma Acute Care Surg. 75(1 Suppl 1):S1-2, 2013. PMID:23778505. 94. Huang J, Huffman JE, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët DA, Chen WM, Smith NL, Kleber ME, Shin SY, Becker DM, Tang W, Dehghan A, Johnson AD, Truong V, Folkersen L, Yang Q, Oudot-Mellkah T, Buckley BM, Moore JH, Williams FM, Campbell H, Silbernagel G, Vitart V, Rudan I, Tofler GH, Navis GJ, Destefano A, Wright AF, Chen MH, de Craen AJ, Worrall BB, Rudnicka AR, Rumley A, Bookman EB, Psaty BM, Chen F, Keene KL, Franco OH, Böhm BO, Uitterlinden AG, Carter AM, Jukema JW, Sattar N, Bis JC, Ikram MA; Cohorts for Heart and Aging Research in Genome Epidemiology (CHARGE) Consortium Neurology Working Group, Sale MM, McKnight B, Fornage M, Ford I, Taylor K, Slagboom PE, McArdle WL, Hsu FC, FrancoCereceda A, Goodall AH, Yanek LR, Furie KL, Cushman M, Hofman A, Witteman JC, Folsom AR, Basu S, Matijevic N, van Gilst WH, Wilson JF, Westendorp RG, Kathiresan S, Reilly MP; CARDIoGRAM Consortium, Tracy RP, Polasek O, Winkelmann BR, Grant PJ, Hillege HL, Cambien F, Stott DJ, Lowe GD, Spector TD, Meigs JB, Marz W, Eriksson P, Becker LC, Morange PE, Soranzo N, Williams SM, Hayward C, van der Harst P, Hamsten A, Lowenstein CJ, Strachan DP, O'Donnell CJ; CHARGE Consortium Hemostatic Factor Working Group. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol. 34:1093-101, 2014. PMID:24578379 95. Karri JV, Cardenas JC, Johansson PI, Matijevic N, Cotton BA, Wade CE, Holcomb JB. In vitro efficacy of RiaSTAP after rapid reconstitution. J Surg Res. 190:655-61, 2014. PMID:24602482 96. Cardenas JC, Matijevic N, Baer LA, Holcomb JB, Cotton BA, Wade CE. Elevated tissue plasminogen activator and reduced plasminogen activator inhibitor promote hyperfibrinolysis in trauma patients. Shock: Injury, Inflammation, and Sepsis. 41:514-21, 2014. PMID:24667610 97. Huby MP, Cardenas JC, Baer LA, Pawelczyk NS, Salsbury JR, Wang YW, Matijevic N, Holcomb JB, Wade CE. Establishment of methods for performing thrombelastography and calibrated automated thrombography in rats. Shock: Injury, Inflammation, and Sepsis. 42:27-30, 2014. PMID:24667614. 98. Cao Y, Dua A, Matijevic N, Wang YW, Pati S, Wade CE, Ko TC, Holcomb JB. Never- Nena Matijevic, PhD Page 30 frozen liquid plasma blocks endothelial permeability as effectively as thawed fresh frozen plasma. J Trauma Acute Care Surg. 77:28-33, 2014. discussion 33. PMID:24977751. 99. Baraniuk S, Tilley BC, del Junco DJ, Fox EE, van Belle G, Wade CE, Podbielski JM, Beeler AM, Hess JR, Bulger EM, Schreiber MA, Inaba K, Fabian TC, Kerby JD, Cohen MJ, Miller CN, Rizoli S, Scalea TM, O'Keeffe T, Brasel KJ, Cotton BA, Muskat P, Holcomb JB; PROPPR Study Group. Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial: Design, rationale and implementation. Injury. 45:1287-95, 2014. PMID:24996573. 100. Matijevic N, Wang YW, Wade CE, Holcomb JB, Cotton BA, Schreiber MA, Muskat P, Fox EE, Del Junco DJ, Cardenas JC, Rahbar MH, Cohen MJ; PROMMTT Study Group. Cellular microparticle and thrombogram phenotypes in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study: correlation with coagulopathy. Thromb Res. 134:652-8, 2014. PMID:25086657. 101. Cardenas JC, Rahbar E, Pommerening MJ, Baer LA, Matijevic N, Cotton BA, Holcomb JB, Wade CE. Measuring thrombin generation as a tool for predicting hemostatic potential and transfusion requirements following trauma. J Trauma Acute Care Surg. 2014 Aug 5. In press, PMID:25099452 C. INVITED ARTICLES IN JOURNALS: 1. Matijevic-Aleksic, N., and Miletic, V.: Platelet aggregation by monomeric and aggregated immunoglobulins. Yugoslav. Med. Biochem. 8: 3-7, 1989. 2. Matijevic-Aleksic, N., and Boskovic, D.: Laboratory control of oral anticoagulant therapy using two different thromboplastins. Yugoslav. Med. Biochem. 11: 55-58, 1992. 3. Wu, K.K., Matijevic-Aleksic, N. Thrombomodulin: A linker of coagulation and fibrinolysis and predictor of risk of arterial thrombosis. Ann. Med. 32; Suppl 1: 73-77, 2000. PMID: 11209986. 4. Matijevic, N., Wu, K.K.: Biochemical characterization of platelet-monocyte interactions by flow cytometry. New Trends in Hematology II. 231-240, 2002. 5. Wu, K.K., and Matijevic-Aleksic, N.: Molecular aspects of thrombosis and antithrombotic drugs. Crit. Rev. Clin. Lab. Sci. 42:249-277, 2005. PMID: 16047540. 6. Matijevic, N., Wu, K.K.: Hypercoagulable states and strokes. Curr. Atheroscler. Rep. 8:324-9, 2006. PMID: 16822399. Nena Matijevic, PhD Page 31 D. OTHER PROFESSIONAL COMMUNICATIONS: 1. NATIONAL AND INTERNATIONAL SCIENTIFIC PRESENTATIONS: 1. 6th Meeting of Yugoslav Society of Hematology and Transfusiology (Portoroz, Yugoslavia, 1976). Pendic B, Matijevic N, Plecas V, Dragovic M. Effects of cytostatics commonly used for the treatment of acute leukemia on platelet aggregation in vitro. 2. VII Yugoslav Congress of Pharmacy (Ohrid, Yugoslavia, 1976). Matijevic N, Pendic B, Zdravkovic M, Ivankovic D. The effect of aspirin on platelet aggregation in vivo and in vitro. 3. I Yugoslav Congress of Gerontology (Belgrade, Yugoslavia, 1977). Matijevic N, Sisic I, Korolija P, Pendic B. Estimation of hemostasis in elderly subjects treated with Complamin®. 4. XV Internal Meeting of Internists, Symposium “Drugs and Health” (Subotica, Yugoslavia, 1977) Zdravkovic M, Matijevic N, Ivankovic D, Pendic B, Tubin M, Cvetkovic G. Platelet aggregation and gastrointestinal complications during the treatment of rheumatic fever with aspirin. 5. III Yugoslav Congress of Hematology and Transfusiology (Sarajevo, Yugoslavia, 1978). Matijevic-Aleksic N, Pajevic M, Milutinovic Dj, Tomasevic R, Pendic B. The influence of platelet storage and temperature on platelet functions. Pajevic M, Matijevic N, Jelic S, Djuric D, Pendic B, Plecas V. Investigation of immunological and hemostatic parameters related to platelets transfusion in patients with malignant hemopathies. Pendic B, Matijevic N. Cytostatics and platelet aggregation. Jelic S, Bojic M, Dragovic M, Miletic V, Matijevic N, Plecas V. Leukemic phase of diffuse histiocytic lymphoma (Reticulum Cell Sarcoma). Miletic V, Jelic S, Gligorovic V, Matijevic N, Plecas V. Physicochemical properties and biologic effects of commercial gamma globulin preparations. 6. VII Congress International de Pharmacologie (Paris, France, 1978). Savic S, Zdravkovic M, Najdanovic B, Ivankovic D, Ristic V, Madic R, Dimitrijevic I, Djordjevic G, Matijevic N. Les effets du Propranolol (Inderal) sur l' hypertension arterielle chez les malades avec des valeurs elevees de l' activite de la renine plasmatique. Nena Matijevic, PhD Page 32 7. International Symposium on Essential Hypertension (Herceg Novi, Yugoslavia, 1978). Savic S, Zdravkovic M, Najdanovic B, Ivankovic D, Djordjevic G, Matijevic N. The activity of plasma rennin and aldosterone in the essential hypertension and the effects of Propranolol on the former. 8. VI Yugoslav Symposium of Immunology (Tara, Yugoslavia, 1979). Matijevic N, Miletic V, Pendic B. Characteristics of platelet aggregation induced by heataggregated immunoglobulins. 9. II Meeting of Yugoslav Society of Hemostasis and Thrombosis (Belgrade, Yugoslavia, 1979). Matijevic N, Miletic V, Pendic B. Aggregation of human blood platelets with monomeric and aggregated immunoglobulins. Jelic S, Matijevic N, Miletic V. Platelet aggregation in vitro in the presence of mixed IgG and IgM cryoglobulins. 10. VII Meeting of Yugoslav Society of Hematology and Blood Transfusion (Split, Yugoslavia, 1980). Matijevic N, Petrovic M, Vidakovic B, Plecas V, Pendic B. Platelet function in cytostatics treated patients. 11. 18th International Congress of the Society of Hematology (Montreal, Canada, 1980). Pendic B, Matijevic N, Dimitrijevic B, Pantic V. Action des agents da la chimiotherapie sur l’ aggregation plaquettaires in vitro. 12. Symposium "Current problems in health care of hematologic patients" (Belgrade, Yugoslavia, 1980). Milenkovic Lj, Tomasevic R, Djuric D, Radovic M, Matijevic N. Comments on certain platelet preparation procedures for transfusion. 13. VI Yugoslav Congress of Clinical Chemistry (Split, Yugoslavia, 1983). Matijevic-Aleksic N, Pendic B. Clinical use of platelet aggregation studies. 14. Yugoslav Congress of Endocrinology (Novi Sad, Yugoslavia, 1984). Pudar-Brankovic G, Matijevic-Aleksic N, Peric Lj, Mijalkovic D, Brankovic S. Platelet aggregation in patients with diabetes mellitus. 15. IV Yugoslav Congress of Hematology and Transfusiology (Skoplje, Yugoslavia, 1984). Matijevic-Aleksic N, Rolovic Z, Pendic B. Platelet function in patients with idiopathic thrombocytopenic purpura. 16. Scientific Meeting of the Serbian Academy of Sciences and Arts, Division of Medical Sciences, "Specific Hypersensitivity of the Body" (Belgrade, Yugoslavia, 1986). Despotovic N, Paranos S, Matijevic-Aleksic N, Rosic D. Platelet aggregation abnormalities in patients with elevated IgE. Nena Matijevic, PhD Page 33 17. V Yugoslav Congress of Hematology and Transfusiology (Maribor, Yugoslavia, 1986). Matijevic-Aleksic N, Petrovic M, Rajic M,Vidakovic B. Antithrombin III in patients with malignant hemopathies. 18. V Yugoslav Symposium on Hemostasis and Thrombosis (Novi Sad, Yugoslavia, 1987). Matijevic-Aleksic N, Rolovic Z. Platelet aggregation in patients with idiopathic thrombocytopenic purpura. 19. VII Yugoslav Congress of Clinical Chemistry (Novi Sad, Yugoslavia, 1987). Matijevic-Aleksic N, Jovic B, Paranos S, Despotovic N. Influence of elevated concentrations of serum IgE on human platelet aggregation. 20. VII Yugoslav Congress of Oncology (Novi Sad, Yugoslavia, 1987). Matijevic-Aleksic N, Petrovic M, Jovic B, Rajic M, Vidakovic B. Hemostasis inhibitors in patients with malignant hemopathies. 21. XXIV Meeting of Oncology and Radiology (Belgrade, Yugoslavia, 1987) Petrovic M, Matijevic-Aleksic N, Plecas V, Radulovic S. Hemostasis abnormalities in malignant diseases. 22. II Dalmatian Meeting of Clinical Chemistry (Split, Yugoslavia, 1988). Matijevic-Aleksic N, Jelic Z, Majkic-Singh N. Protein C and oral anticoagulant therapy. Starcevic D, Matijevic-Aleksic N, Jelic-Ivanovic Z. C1-esterase inactivator in malignant diseases. 23. IX Meeting of Yugoslav Society of Hematology and Transfusiology (Novi Sad, Yugoslavia, 1988). Matijevic-Aleksic N, Petrovic M, Plecas V, Vidakovic B, Panajotovic-Jovic B. Comparisons of hemostatic parameters in patients with malignant diseases. 24. VI Yugoslav Meeting of the Society of Hemostasis and Thrombosis (Ljubljana, Yugoslavia, 1990). Matijevic N, Elezovic I, Rolovic Z. Plasma levels of thrombin-antithrombin (TAT) complex in patients with acute leukemia. Matijevic N, Elezovic I, Rolovic Z. Plasma levels of fibrinogen and fibrin degradation products in patients with acute leukemia. Elezovic I, Matijevic N, Rolovic Z. Plasma levels and activities of factor XIII in patients with acute leukemia. 25. 11th International Congress on Thrombosis (Ljubljana, Yugoslavia, 1990). Matijevic-Aleksic N, Boskovic D, Rolovic Z. Monitoring of an oral anticoagulant therapy using two different thromboplastins. Nena Matijevic, PhD Page 34 Matijevic-Aleksic N, Jelic-Ivanovic. Functional assay of Protein C in patients on oral anticoagulant therapy. 26. 6th Yugoslav Congress of Hematology and Transfusiology (Zagreb, Yugoslavia, 1990). Matijevic-Aleksic N, Elezovic I, Marisavljevic D, Colovic M, Rolovic Z. Thrombinantithrombin III complex in acute leukemia. Elezovic I, Matijevic N, Boskovic D, Mijovic A, Tomin D, Colovic M, Novak A, Rolovic Z. Disseminated intravascular coagulation in patients with acute promyelocytic leukemia. 27. VIII Yugoslav Scientific Meeting of Alergology and Clinical Immunology (Kopaonik, Yugoslavia, 1990). Matijevic-Aleksic N, Elezovic I, Rolovic Z, Dimcic Z, Stefanovic Lj. Laboratory manifestation of a lupus-like anticoagulant: case report. Matijevic-Aleksic N, Dimcic Z, Rolovic Z. Protein C and Protein S in systemic diseases. Elezovic I, Matijevic-Aleksic N, Jancic A, Markovic Lj, Bonaci-Nikolic B, Djordjevic S. Anticardiolipin antibodies in patients with immune thrombocytopenic purpura. Dimcic Z, Bukulica M, Djordjevic S, Matijevic-Aleksic N, Markovic Lj, Tanurdcic S, Djuric M. Hemostatic abnormalities in patients with systemic lupus erythematosus associated with a presence of anticardiolipin antibodies. Dimcic Z, Bonaci-Nikolic B, Markovic Lj, Matijevic-Aleksic N, Balaban J, Tanurdcic. A case of cerebral systemic lupus erythematosus associated with anticardiolipin antibodies. 28. XIII Congress of the International Society on Thrombosis and Haemostasis (Amsterdam, Netherlands, 1991). Matijevic-Aleksic N, Elezovic I, Suvajdic N, Rolovic Z. Levels of fibrinopeptide A and thrombin-antithrombin III complex in patients with acute leukemia. Elezovic I, Matijevic-Aleksic N, Marisavljevic D, Suvajdic N, Rolovic Z. Fibrinolysis and fibrinogenolysis in acute leukemia. 29. 12th International Congress on Thrombosis (Florence, Italy, 1992). Matijevic-Aleksic N, Dulic B, Rolovic Z. Markers of hemostasis activation after total hip replacement. 30. International Meeting of Cardiology (Amsterdam, Netherlands, 1992). Simic N, Avramovic D, Matijevic-Aleksic N, Stevic S, Kalimanovska-Ostric D. Indobufen treatment of angina pectoris: effects on platelet aggregation. 31. 35th Annual Meeting of the American Society of Hematology (St. Louis, MO, 1993). Nena Matijevic, PhD Page 35 Aleksic N M, Sanduja, S K, Long, C, Wu, K K. Coordinate expression of prostaglandin H synthase and thromboxane A synthase in phorbol-induced differentiation of a megakaryocyte cell line (MEG-01). 32. 9th International Conference on Prostaglandins and Related Compounds (Florence, Italy, 1994). Wu, K.K., Sanduja, S.K, Tsai, A.-L., and Matijevic-Aleksic, N. Quantitative analysis of prostaglandin H synthase (PGHS-1) decay in cells over expressing PGHS-1. 33. 1st Yugoslav Hematology Congress (Belgrade, Yugoslavia, 1994). Elezovi I, Matijevic-Aleksic N, Boskovic D, Colovic M, Mijovic AS, Tomin D, Mijovic AM, Suvajdic N, Vidovic A, Rolovic Z. Disorders of hemostasis in acute leukemia. Elezovic I, Matijevic-Aleksic N, Colovic M, Boskovic D, Mijovic AS, Tomin D, Mijovic AM, Suvajdic N, Maric A, Rolovic Z. Disseminated intravascular coagulation in acute leukemia. 34. 36th Annual Meeting of the American Society of Hematology (Nashville, TN, 1994). Matijevic-Aleksic N, Ghaddar H, McPhedran P, Wu KK. Bleeding disorder due to platelet cyclooxygenase-1 (COX-1) deficiency. 35. XV Congress of the International Society on Thrombosis and Haemostasis (Jerusalem, Israel, 1995). Elezovic I, Matijevic-Aleksic N, Rolovic Z. Elastase alpha-1 proteinase inhibitor complexes in acute leukemia. 36. 38th Annual Meeting of the American Society of Hematology (Orlando, FL, 1996). Matei MC, Aleksic N, Ahn C, Wu KK, Juneja HS. Hemostasis activation markers in sickle cell disease: association with painful crisis. 37. X Yugoslav Hematology Days with International Attendance (Niska Banja, Yugoslavia, 1996). Elezovic I, Pilic Z, Nedeljkovic N, Marisavljevic D, Matijevic-Aleksic N, Miljic P, Radosevic N, Todorovic-Tirnanic M: Caesare section in a case with Bernard-Suilier syndrome. Elezovic I, Matijevic-Aleksic N, Rolovic Z: The role of elastase in coagulation disorders of acute leukemia patients. 38. XVI Congress of the International Society on Thrombosis and Haemostasis (Florence, Italy, 1997). Ghaddar HM, Aleksic N, Hearne LB, Folsom AR, Chambless LE, Morrissey JH, Wu KK. The ARIC postprandial study: relation of factor VII with factor VII gene polymorphism and triglyceride levels in carotid atherosclerosis cases and controls. 39. 71st Scientific Session of the American Heart Association (Dallas, Texas, 1998). Nena Matijevic, PhD Page 36 Folsom AR, Rosamond WD, Shahar E, Cooper LS, Aleksic N, Nieto FJ, Rasmussen M, Wu KK. Prospective study of markers of hemostatic function, inflammation, and endothelial function with risk of ischemic stroke. Salomaa V, Matei MC, Aleksic N, Sansores-Garcia L, Folsom AR, Juneja H, Chambless LE, Wu KK. Soluble thrombomodulin as a predictor of incident coronary heart disease: The ARIC study. 40. 40th Annual Meeting of the American Society of Hematology (Miami Beach, FL, 1998) Aleksic N, Juneja H, Folsom AR, Ahn C, Boerwinkle E, Chambless W, Wu KK. Prospective study of platelet PlA1/A2 polymorphism, platelet activation and incidence of coronary heart disease. 41. XVII Congress of the International Society on Thrombosis and Haemostasis (Washington, DC, 1999). Wu KK, Aleksic N, Ahn C, Boerwinkle E, Folsom A, Juneja H. Association of thrombomodulin 455A/V dimorphism with risk of developing coronary heart disease. Aleksic N, Ahn C, Boerwinkle E, Juneja H, Folsom AR, Wu KK. Factor XIII V34L polymorphism and the risk for development of coronary heart disease. Afshar-Kharghan V, Aleksic N, Ahn C, Boerwinkle E, Wu KK, Lopez JA. Prospective study of the association of the variable number of tandem repeats (VNTR) polymorphism in platelet glycoprotein (GP) Ib alpha and incidence of coronary heart disease. 42. 41th Annual Meeting of the American Society of Hematology (New Orleans, LA, 1999). Wu KK, Matijevic-Aleksic N, Ahn C, Boerwinkle E, Folsom AR, Juneja H. Thrombomodulin 455A/V dimorphism is a risk factor for developing coronary heart disease in African Americans but not in Caucasians: The ARIC Study. 43. 40th Annual Conference on Cardiovascular Disease Epidemiology and Prevention (San Diego, CA, 2000). Folsom AR, Aleksic N, Salomaa V, Park E, Juneja H, Wu KK. Fibrinolytic variables and incident CHD in the Atherosclerosis Risk in Communities (ARIC) Study 44. 28th Congress of the International Society of Hematology (Toronto, Canada, 2000). Elezovic I, Matijevic-Aleksic N, Rolovic Z, Boskovic D, Colovic M. Hypercoagulability in patients with acute leukemia prior to therapy. 45. 42nd Annual Meeting of the American Society of Hematology (San Francisco, CA, 2000). Aleksic N, Ahn C, Juneja H, Boerwinkle E, Ballantyne CM, Wu KK. Effect of interaction of plasma soluble thrombomodulin (sTM) and soluble intercellular adhesion molecule-1 (sICAM-1) on predicting risk of incident coronary heart disease (CHD): The ARIC Study. 46. 7th Annual Texas Forum of Female Reproduction (Houston, TX, 2001). Nena Matijevic, PhD Page 37 Tumbusch KJ, Goldsby J, Arbab F, Matijevic-Aleksic N, Huang J-C. The expression of prostaglandin H synthase-2 and the profile of arachidonic acid metabolism by human fallopian tubes. 47. 57th Annual Meeting of the American Society for Reproductive Medicine (Orlando, FL, 2001). Tumbusch KJ, Goldsby J, Arbab F, Matijevic-Aleksic N, Huang J-C. The expression of prostaglandin H synthase-2 and the profile of arachidonic acid metabolism by human fallopian tubes (P-466). 48. XVIII Congress of the International Society on Thrombosis and Haemostasis (Paris, France, 2001). Aleksic N, Ahn C, Juneja H, Boerwinkle E, Ballantyne C, Wu KK. Effect of interaction of plasma soluble thrombomodulin (sTM) and soluble intercellular adhesion molecule-1 (sICAM-1) on predicting risk of incident coronary heart disease (CHD): The ARIC Study. Aleksic N, Folsom AR, Cushman M, Heckbert SR, Tsai M, Wu KK. Soluble plasma thrombomodulin (sTM), TM genotype, and risk of venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE) Study. Folsom AR, Cushman M, Tsai MY, Aleksic N, Heckbert SR, Boland LL, Tsai AW, Yanez ND, Rosamond WD. Prospective study of venous thromboembolism in relation to factor V Leiden and related factors: The Longitudinal Investigation of Thromboembolism Etiology (LITE) Study. Tsai A, Cushman M, Tracy RP, Heckbert SR, McGovern P, Aleksic N, Rosamond WD, Folsom AR. A prospective study of factor VIIIc and von Willebrand factor in relation to venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE) Study. Cushman M, Folsom AR, Wang L, Heckbert SR, White R, Aleksic N, Tsai MY, Tracy RP. Concentration of Thrombin Activable Fibrinolysis Inhibitor (TAFI), a polymorphism of the TAFI gene, and the risk of venous thrombosis in a prospective study: The Longitudinal Investigation of Thromboembolism Etiology (LITE) Study 49. 43rd Annual Meeting of the American Society of Hematology (Orlando, FL, 2001). Matijevic-Aleksic N, Ahn C, Wang W, Juneja H, Wu KK. Differential association of thrombomodulin A455V polymorphism with risk of incident coronary heart disease (CHD) and ischemic stroke: The ARIC study. Wu KK, Matijevic-Aleksic N, Ahn C, Juneja H, Wang Y-W. A positive interaction between plasma thrombomodulin and fibrinogen or factor VIII in predicting incident coronary heart disease. Cushman M, Folsom AR, Aleksic N, Rosamond WD, Tracy RP, Heckbert SR. Fibrin fragment D-dimer and the risk of future venous thrombosis. Nena Matijevic, PhD Page 38 50. 57th Annual Meeting of the American Society for Reproductive Medicine (Orlando, FL, 2001). Huang J-C, Wun W-S A, Goldsby JS, Matijevic-Aleksic N, Wu KK. Prostacyclin enhances embryo hatching. 51. 1st Serbian Congress of Hematology (Belgrade, Serbia, 2002) Matijevic N, Wu KK. Biochemical characterization of platelet-monocyte interactions by flow cytometry. 52. XIX Congress of the International Society on Thrombosis and Hemostasis (Birmingham, UK, 2003). Matijevic-Aleksic N, Ahn C, Afshar-Kharghan V, Sweetman R, Lopez JA, Nugent DJ, Boerwinkle E, Wu KK. Coexistence of multiple hemostatic genetic risk factors does not increase risk of coronary heart disease. 53. XXI Congress of the International Society on Thrombosis and Haemostasis (Geneva, Switzerland, 2007). N. Matijevic, R. Radovancevic, A. Bracey, B. Radovancevic, I. Gregoric, O. Frazier. Platelet and monocyte activation in patients undergoing circulatory support with left ventricular assist devices (LVAD). 54. XVIIth Regional Congress of the International Society of Blood Transfusion (Madrid, Spain, 2007). Radovancevic R, Radovancevic B, Bracey A, Matijevic N, Carranza S, Gregoric I, Frazier OH. Effect of platelet activation on bleeding and transfusion rates in patients undergoing high risk cardiac surgery. 55. 12th Congress of the European Hematology Association (Vienna, Austria, 2007). Matijevic N, Bracey AW, Radovancevic B, Radovancevic R, Gregoric ID, Frazier OH. Increased leukocyte-platelet interactions associated with high risk heart surgery. Bracey AW, Radovancevic R, Matijevic N, Radovancevic B, Carranza S, Gregoric I, Frazier OH. Transfusion rates and platelet activation in patients undergoing high risk cardiac surgery. 56. 20th International Congress on Thrombosis (Athens, Greece, 2008) N Aleksic, D Catellier, KK Wu, G Heiss, AR Folsom. Monocyte and platelet markers in peripheral arterial disease (PAD): ARIC Carotid MRI study. 57. 48th Cardiovascular Disease Epidemiology and Prevention Annual Conference (Colorado Springs, CO, 2008). Matijevic N, Catellier D, Wu KK, Heiss G, Folsom AR. Association of monocyte and platelet markers with peripheral arterial disease: ARIC Carotid MRI Study. Nena Matijevic, PhD Page 39 Yamagishi K, Aleksic N, Hannan P, Juneja H, Folsom AR. Coagulation factors II, V, IX, X, XI, XII, plasminogen and α-2 antiplasmin and risk of coronary heart disease: a case-cohort study in ARIC . 58. 32nd Annual Conference on Shock (San Antonio, TX, 2009). N Matijevic, W Wang, S Pati, R Kozar, J Conyers, and J Holcomb. Phenotypic assessment of cellular microparticles in fresh frozen plasma during storage. J Holcomb, M Gerber, R Kozar, R Parthasarthy, N Matijevic, MF Doursout, T Ko, B Hartwell, J Conyers and S Pati. Protective effects of plasma (FFP) on pulmonary and lymphatic endothelial permeability diminish between day 0 through day 5 after thaw. 59. Experimental Biology Meeting (New Orleans, LA, 2009) Doursout MF, Liang YY, Pati S, Matijevic N, Holcomb J.B: Role of the NF-кB pathway in rats subjected to moderate hemorrhage. 60. XXII Congress of the International Society on Thrombosis and Haemostasis (Boston, MA, 2009). Matijevic N, Dong JF, Hartwell E, Pati S, Holcomb JB. The protective effects of fresh thawed plasma (FFP) on endothelial permeability are correlated with changes in thrombospondin-1 microparticles. Matijevic N, Wu KK, Howard AG, Wasserman B, Wang W, Folsom AR, Sharrett R. Association of blood cellular markers with carotid plaque size and composition. 61. Joint Conference - 50th Cardiovascular Disease Epidemiology and Prevention - and Nutrition, Physical Activity, and Metabolism (San Francisco, CA, 2010). Nettleton JA, Matijevic N, Follis JL, Folsom AR, and Boerwinkle E. Dietary Patterns and Flow Cytometry-Measured Biomarkers of Inflammation and Cellular Activation. Kucharska-Newton A, Monda K, Campbell S, Wagenknecht L, Boerwinkle E, Wasserman B, Aleksic-Matijevic N, Heiss G. Markers of Platelet Activation and Carotid Artery Plaque Morphology: The Atherosclerosis Risk in Communities (ARIC) Study. Kucharska-Newton A, Monda K, Avery C, Folsom A, Aleksic-Matijevic N: Longitudinal predictors of levels of in vivo platelet activation markers: The Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study. 62. 33th Annual Conference on Shock (Portland, OR, 2010) W Wang, JB Holcomb, V. Kostousov, N. Matijevic. Diminished hemostatic potential of thawed plasma measured by two novel assays. V Kostousov, N Matijevic, JB Holcomb. Deficiency of protein C inhibitor activity in liquid plasma stored at 4ºC for 5 days. Nena Matijevic, PhD Page 40 N Matijevic, W. Y-W Wang, R Kozar, E Gonzales, JB Holcomb. Low levels of platelet microparticles correlate with poor outcomes in shock patients. Alrehami N, Matijevic N, Doursout MF, Dong JF, Cruz MA, Holcomb JB and Vijayan KV. Regulation of protein phosphatas 2B activity and the exocytosis of von Willebrand factor in hemorrhagic shock. 63. Advanced Technology Applications for Combat Casualty Care (ATACCC) (St.Petersburg, FL, 2010). JB Holcomb, MH Rahbar, DJ del Junco, J Zhang, EE Fox, N Matijevic, BA Cotton, MJ Cohen, MA Schreiber and the PROMMTT Investigators. Initial Report from PROMMTT: The DoD Sponsored Prospective, Observational, Multi-Center Massive Transfusion Study. 64. 69th Meeting of the American Association for the Surgery of Trauma (Boston, MA, 2010) Matijevic N, Wang Y-W W, Kostousov V, Letourneau P, and Holcomb JB. Multiple levels of degradation diminish aged plasma’s hemostatic potential 65. Western Trauma association (WEST) (Big Sky, Montana, 2011) Letourneau P, McManus M, Sowards K, Wang W, Pati S, Matijevic N, Wade CE, Holcomb JB. Aged Plasma Transfusion Increases Mortality in Rat Model of Uncontrolled Hemorrhage. 66. 34rd Annual Conference on Shock (Norfolk, Virginia, 2011) Matijevic N, Kostousov V, Wang Y-WW, Wade CE, Holcomb JB. Hemostatically distinct FFPs equally improve abnormal TEG variables in an in vitro dilutional coagulopathy model. Kostousov V, Matijevic N, Wang Y-WW, Holcomb JB, Cotton BA, Wade CE. Hyperfibrinolytic TEG pattern in diluted blood is provoked by tissue factor. Pawelczyk NS, Salsbury JR, Baer L, Wang Y, Matijevic N, Letourneau PA, Holcomb JB, Wade CE. Blood loss after hemodilution and uncontrolled hemorrhage is a function of preinjury MAP and not dilutional coagulopathy. 67. Conference of the Advanced Technology Applications for Combat Casualty Care (ATACCC) (Fort Lauderdale, FL, 2011). Matijevic N, Kostousov V, Wang Y-W W, Wade CE, Cotton BA, Holcomb JB. The prevalence of thrombogram-based APC resistant phenotypes among FFP donors. Radwan ZA, Bai Y, Matijevic N, del Junco DJ, McCarthy JJ, Wade CE, HolcombJB , Cotton BA. An emergency department thawed plasma protocol decreases blood component utilization and improves survival in severely injured patients. Wade C, Holcomb JB, Eastridge BJ, Jones J, Del Junco DJ, Rahbar MH and the PROMMTT investigators. In-hospital mortality of civilian and military casualties receiving a blood transfusion. Nena Matijevic, PhD Page 41 Holcomb J and the PROMMTT study investigators: Initial report from PROMMTT: The Prospective, Observational, Multi-Center Massive Transfusion Study. Huby MP, Pawelczyk NS, Salsbury JR, Baer L, Wang Y, Matijevic N, Letourneau PA, Holcomb JB, Wade CE. Blood loss after hemodilution and uncontrolled hemorrhage is a function of pre-injury MAP and not dilutional coagulopathy. Cotton BA, Kostousov V, Radwan ZA, Pivalizza E, Podbielski J, Matijevic N, Wade CE, Holcomb JB. Hyperfibrinolysis on admission is an uncommon but highly lethal event associated with shock and prehospital crystalloid administration. 68. 70th Meeting of the American Association for the Surgery of Trauma (Chicago, IL, 2011). Matijevic N, Kostousov V, Wang Y-W W, Wade CE, Cotton BA, Holcomb JB. The prevalence of thrombogram-based APC resistant phenotypes among FFP donors. Cotton BA, Minei KM, Radwan ZA, Matijevic N, Pivalizza E, Podbielski J, Wade CE Kozar RA, Holcomb JB. Admission rapid thrombelastography (r-TEG) predicts development of pulmonary embolism in trauma patients. Radwan ZA, Bai Y, Matijevic N, del Junco D, McCarthy JJ, Wade CE, Holcomb JB, Cotton BA. An emergency department thawed plasma protocol decreases blood component utilization and improves survival in severely injured patients. 69. American Association of Blood Banks Annual Meeting (San Diego, CA, 2011). Matijevic N, Kostousov V, Wang Y-WW, Hartwell B, Holcomb JB. Higher Hemostatic Potential in the Presence of the Activated Protein C in FP24 Compared to FFP. 70. Annual Meeting of the American Society of Hematology (San Diego, CA, 2011). Cotton BA, Sixta S, Wade CE, Holcomb JB, Matijevic N. Mechanistics determinants of the acute coagulopathy of trauma (ACoT) in patients undergoing emergency surgery. 71. 25th Annual Scientific Assembly, Eastern Association for the Surgery of Trauma (EAST), (Lake Buena Vista, FL, 2012). Cotton BA, Matijevic N, Minei K, Kostousov V, Radwan ZA, Pivalizza E, Wade CE, Holcomb JB. Hyperfibrinolysis on admission is an uncommon but highly lethal event associated with shock and prehospital crystalloid administration. 72. 7th Congress of the International Federation of Shock Societies and 35th Annual Congress on Shock (Miami Beach, FL, 2012). Matijevic N, Kostousov V, Wang Y-WW, Wade CE, Holcomb JB, Cotton BA. Low dose of tranexamic acid reverses hyperfibrinolytic TEG in an in vitro traumatic coagulopathy model. 73. 71st Annual Meeting of the American Association for Surgery of Trauma and Clinical Congress of Acute Care Surgery (AAST) (Kauai, HI, 2012). Nena Matijevic, PhD Page 42 Matijevic N, Wang Y-W, Cotton BA, Hartwell E, Barbeau J, Holcomb JB. Superior hemostatic profiles of never frozen liquid plasma (LQP) compared to thawed fresh frozen plasma (TP). 74. Annual Meeting of the American Association of Blood Banks (AABB), (Boston, MA, 2012). Matijevic N, Wang W, Hartwell E, Cotton B, Wade CE, Barbeau J, Holcomb JB. Clotting properties of never frozen liquid plasma during 26 days of cold storage. 75. Thrombosis and Hemostasis Summit of North America (Chicago, IL, April 2013) CardenasJ, Wang W, Baer L, Matijevic N, Cotton BA, Holcomb JB, Wade CE. Autologous Cleavage of the GPIbα Receptor Promotes Platelet Dysfunction Following Trauma 76. Surgical Forum of the American College of Surgeon’s 99th Clinical Congress (Washington, D.C., 2013). Goodman MD, Farley DL, Cardenas JC, Pommerening M Podbielski J, Matijevic N, Wade CE, Holcomb JB, Cotton BA. Thrombelastography velocity curve values more accurately predict clinically significant fibrinolysis. 77. XXIV Congress of the International Society on Thrombosis and Haemostasis (ISTH), (Amsterdam, Netherlands, 2013). Matijevic N, Y-W Wang, JB Holcomb, BA Cotton, CE Wade, MA Schreiber, P Muskat, JG Myers, and MJ Cohen, on behalf of the PROMMTT study group. Circulating microparticles and thrombin generation in the PROMMTT study: association with coagulopathy and survival. Cardenas JC, Matijevic N, Cotton BA, Holcomb JB, Wade CE. Contribution of the plasminogen activation system during hyperfibrinolysis in trauma-induced coagulopathy. 78. The American Heart Association Resuscitation Science Symposium (Dallas, TX, 2013). Cardenas JC, Wang YW, Baer LA, Matijevic N, Cotton BA, Holcomb JB, Wade CE.: Autologous Cleavage of the GPIbα Receptor Promotes Platelet Dysfunction Following Trauma. 79. 27th Annuall Scientific Assembly of The Eastern Association for Surgery of Trauma (EAST), (Naples, FL) Dua, A, Cao Y, Matijevic N, Wang Y-W, Pati S, Wade CE, Ko TC, Holcomb JB. Never frozen liquid plasma blocks endothelial permeability as effectively as thawed fresh frozen plasma. 80. The Western Trauma Association (Steamboat Springs, CO, 2014). Cardenas JC, Baer LA, Matijevic N, Cotton BA, Holcomb JB, Wade CE. Measuring thrombin generation as a tool for predicting hemostatic potential and transfusion requirements following trauma. 81. The 7th Symposium on Hemostasis (Chapel Hill, NC, 2014). Nena Matijevic, PhD Page 43 Cardenas JC, Wang YW, Baer LA, Matijevic N, Cotton BA, Holcomb JB, Wade CE.: Role of GPIbα Receptor Shedding in Platelet Dysfunction Following Trauma. 2. NON-REFEREED PUBLICATIONS 1. Zdravkovic M, Matijevic N, Ivankovic D, Pendic B, Tubin M, Cvetkovic G. Platelet aggregation and gastrointestinal complications during therapy of rheumatic fever by acetylsalicylic acid. Proc Symp Internists Drugs Health, Subotica, 229-234, 1977. 2. Matijevic-Aleksic N, Pajevic M, Milutinovic Dj, Tomasevic R, Pendic B. The influence of storage and temperature on some functions of platelet suspensions. Proc III Yug Hematology and Transfusiology Congress, Sarajevo, 905-909, 1978. 3. Pudar-Brankovic G, Matijevic-Aleksic N, Peric Lj, Mijalkovic D, Brankovic P. Platelet aggregation in patients with diabetes mellitus. Proc III Yug Endocrinology Congress, Novi Sad, 547, 1984. 3. OTHER WORKSHOPS 1. Atherosclerosis Risk in Communities (ARIC) Steering Committee Meetings, National Heart, Lung, and Blood Institute (NHLBI), NIH, Bethesda, MD, once or twice per year, 19962005. 2. “Transagency Coagulopathy in Trauma Workshop”, National Heart, Lung, and Blood Institute (NHLBI) and Department of Defense (DoD), NIH, Bethesda, MD, April 5-6, 2010. 3. “Acute Trauma Sample Processing from Injury Site”, The Division of Blood Diseases and Resources (DBDR), National Heart, Lung, and Blood Institute (NHLBI), NIH, Bethesda, MD, April 1, 2011 4. Pragmatic Observational Plasma and Platelet Ratio (PROPPR) Investigators Meeting, La Torreta Lake Resort, Lake Conroe, Montgomery, TX, July 18-20, 2011. 5. Pragmatic Observational Plasma and Platelet Ratio (PROPPR) Investigators Meeting, La Torreta Lake Resort, Lake Conroe, Montgomery, TX, Jan 18-20, 2012. 6. Pragmatic Observational Plasma and Platelet Ratio (PROPPR) Investigators Meeting, Houston, TX, Jan 30-31, 2013. Nena Matijevic, PhD Page 44 7. Pragmatic Observational Plasma and Platelet Ratio (PROPPR) Investigators Meeting, Houston, TX, Jan 30-31, 2014. Nena Matijevic, PhD Page 45