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DANIEL C. LEE, M.D. CURRICULUM VITAE Revised 6/2014 OFFICE ADDRESS Section of Thoracic and Cardiovascular Surgery Department of Surgery University of Oklahoma School of Medicine 920 Stanton L. Young Boulevard G. Rainey Williams Pavillion Suite 2230 Oklahoma City, OK 73104 Phone: (405) 271-5789 Fax: (405) 271-3288 Email: [email protected] CITIZENSHIP U.S.A. EDUCATION DEGREE 1989-1993 University of California at San Diego Major: Bioengineering 1993-1997 University of Chicago Pritzker School of Medicine B.S., June, 1993 M.D., June, 1997 POSTDOCTORAL TRAINING 1997-1999 Loyola University of Chicago Stritch School of Medicine General Surgery Internship 1999-2002 Columbia University College of Physicians and Surgeons New York Presbyterian Hospital NIH Fellowship and Thoracic Transplantation 2002-2005 Yale University School of Medicine Yale-New Haven Hospital General Surgery Residency 2005 Memorial Sloan-Kettering Cancer Center Thoracic Surgery Fellowship 2005-2008 Weill Medical College of Cornell University New York Presbyterian Hospital Cardiothoracic Surgery Residency ACADEMIC APPOINTMENTS 20014- Associate Professor of Surgery University of Oklahoma School of Medicine 2008-2014 Assistant Professor of Surgery State University of New York Downstate Medical Center 2008-2014 Assistant Professor Joint Program in Biomedical Engineering School of Graduate Studies State University of New York Downstate Medical Center And NYU-Polytechnic University HOSPITAL APPOINTMENTS 2014- Attending Cardiothoracic Surgeon University of Oklahoma Medical Center 2014- Attending Cardiothoracic Surgeon Oklahoma City VA Medical Center 2 2008-2014 Attending Cardiothoracic Surgeon State University of New York Downstate Medical Center COMMITTEES State University of New York, Downstate Medical Center: Surgical Research Committee, Chair Cardiothoracic Surgery Clerkship, Director Patient Safety Committee Surgical Performance Improvement Committee Cardiothoracic Surgery Operations Committee Peri-Operative Performance Improvement Committee Cardiovascular Product Line Committee OR Committee LICENSURE Oklahoma (#30425) New York (#218996) Illinois (#036-105131) BOARD CERTIFICATION American Board of Surgery (#51580) American Board of Thoracic Surgery (#7774) 3 PROFESSIONAL MEMBERSHIPS Society of Thoracic Surgeons American College of Surgeons Yale Surgical Society Cardiothoracic Surgery Network Optical Society of America HONORS AND AWARDS 1992 Golden Key National Honor Society 1992 UCSD Research Scholar Award 1993 Phi Beta Kappa 1993 Magna Cum Laude Graduate 2002 Inglenook Oncology Young Investigator Award, American Association for Cancer Research RESEARCH EXPERIENCE 1991-1993 University of California, Department of Applied Mechanics and Engineering Sciences, Dr. A. D. McCulloch; Residual stress in the myocardium 1993-1996 University of Chicago, Department of Surgery, Dr. H. S. Bassiouny; Heart rate variability and experimental atherogenesis 1999-2002 Columbia University, Department of Surgery, Dr. M. C. Oz, and Department of Anesthesia, Dr. E. Bennett-Guerrero; Antioxidants and high risk cardiac surgery 1999-2002 Columbia University, Department of Surgery, Dr. M. C. Oz and Dr. W. Ting; Clinical implications of the New York Cardiac Surgery Registry 1999-2002 Columbia University, Department of Surgery, Dr. M. C. Oz, and Department of Biomedical Engineering, Dr. E. F. Leonard; Visualization through blood 1999-2002 Columbia University, Department of Surgery, Dr. D. M. Stern and Dr. A. M. Schmidt; Receptor for advanced glycation end products and tumor biology 4 2001-2002 Columbia University, Department of Surgery, Dr. J. J. Kandel and Dr. A. M. Schmidt; Angiogenesis and tumor biology 2008- State University of New York-Downstate Medical Center, Dr. M. Zhang; Ischemia reperfusion and autoimmune response 2008- State University of New York-Downstate Medical Center, Dr. R. Barbour; Optical tomography in cardiac surgery RESEARCH SUPPORT DATE SOURCE AMOUNT ROLE 1994 NIH Student Research Fellowship Heart Rate Variability and Experimental Carotid Atherogenesis $3,000 PI 1995-1996 Lifeline Foundation of the Society for Vascular $3,000 Surgery and International Society for Cardiovascular Surgery Student Research Award Heart Rate Variability and Experimental Coronary Atherogenesis Columbia University Surgical Research Grant $5,000 Endoscopic Visualization through Blood PI 2001-2002 Columbia University Surgical Research Grant Antioxidants and High Risk Cardiac Surgery PI 1999-2002 NIH/NHLBI Individual NRSA Grant $120,000 (F32HL10191) Hyperhomocysteinemia and Diabetic Atherosclerosis PI 2007-2011 NIH/NINDS (R44NS049734) Functional Brain Imaging by Optical Tomography $400,000 SUNY PI 2008- New York State Department of Health Empire Clinical Research Investigator Program in Optical Tomography $700,000 PI 2010- NIH/NINDS (R21NS067278) $500,000 PI Neurocognitive Function and Cerebral Perfusion in Cardiac Surgery 2010-2014 NIH/GlaxoSmithKline/Pronova/Sigma-Tau Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation 2000-2001 5 $6,000 PI est. $100,000 SUNY PI 2011-2014 SUNY Downstate College of Medicine Research Initiative Award Prediction of Outcomes after Cardiac Surgery in an Inner-City, predominately Black Population: Impact of Psychosocial Variables and Adherence $15,000 Co-investigator 2011 SUNY Downstate College of Medicine Graduate Research Initiative Award $50,000 PI JOURNAL REVIEWER Annals of Surgery Cardiology Journal of Long-term Effects of Medical Implants Journal of Thoracic and Cardiovascular Surgery EDITORSHIP Guest Associate Editor, Cardiology PHD THESIS ADVISED Douglas Pfeil 2011- POSTDOCTORAL FELLOWS MENTORED Onyeoziri Nwanguma, MD 2008-09 Current Position: Bariatric Surgeon, The Medical Center of Bowling Green, Ky Sergio Ramirez, MD 2009-11 Current Position: Resident in Surgery, SUNY Downstate Medical Center, Brooklyn, NY LeRone Simpson, MD 2009-11 Current Position: Resident in Surgery, Texas Tech University Health Sciences Center, Lubbock, TX 6 Tigran Gevorgyan, MD 2011- 2013 Current Position: Resident in Medicine, Interfaith Medical Center, Brooklyn, NY Dzenan Lulic, MD 2012- 2013 Current Position: Resident in Orthopedic Surgery, Kingsbrook Jewish Hospital, Brooklyn, NY PUBLICATIONS Bassiouny, H.S., Lee, D.C., Zarins, C.K., Glagov, S., "Low Diurnal Heart Rate Variability Inhibits Experimental Carotid Stenosis.” Surgical Forum 46, 1995. Lee, D.C., Ting, W. “Tissue versus Metal Valves: Weighing the Factors.” Healthology Cardio Health 234, 2000. Lee, D.C., Oz, M.C., Lin, S.X., Weinberg, A.D., Ting, W. “Quality of Care and Outcome in Coronary Revascularization: Are There any Differences between Mandatory and Voluntary Reporting?” Surgical Forum 51: 523-524, 2000. Taguchi, A., Blood, D.C., Del Toro, G., Canet, A., Lee, D.C., Qu, W., Tanji, N., Lu, Y., Lalla, E., Fu, C., Hofmann, M.A., Kislinger, T., Ingram, M., Lu, A., Tanaka, K., Hori, O., Ogawa, S., Stern, D.M., Schmidt, A.M. “Blockade of RAGE – amphoterin signalling suppresses tumour growth and metastases.” Nature 405:354-360, 2000. Comment in: Nature 405:287-288, 2000. Lee, D.C., Oz, M.C., Weinberg, A.D., Lin, S.X., Ting, W. “Optimal Timing of Revascularization: Transmural Versus Nontransmural Acute Myocardial Infarction.” Annals of Thoracic Surgery 71:1198-204, 2001. Lee, D.C., Qu, W, Lu, Y., Stern, D.M., Schmidt, A.M. “Blockade of RAGE Suppresses Growth, Metastases, and Progression of Mammary Tumors in a Murine Model of Breast Cancer.” Surgical Forum 52: 274-276, 2001. Grimblatov, V., Lee, D.C., Oz, M., Leonard, E.F. "Spectral Analysis of Optical Imaging Through Blood." Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII, Bass, L.S., Kollias, N., Malek, R.S., Katzir, A., Bartels, K.E. Tate, L.P., Peavy, G.M., Lucroy, M.D., Shaw, U.K., Wong, B.J., Trowers, E.A., Woodward, T.A., de Riese, W.T., Gregory, K.W., Editors, Proceedings of the International Society for Photo-optical Engineering 4609:438-48. 2002. Bucciarelli, L.G., Wendt, T., Qu, W., Lu, Y., Lalla, E., Rong, L.L., Goova, M.T., Moser, B., Kislinger, T., Lee, D.C., Kashyap, Y., Stern, D.M., Schmidt, A.M. “ RAGE Blockade Stabilizes Established Atherosclerosis in Diabetic Apolipoprotein E-null Mice.” Circulation 106:2827-35, 2002. Comment in: Circulation 106:2760-2763. 7 Bassiouny, H.S., Zarins, C.K., Lee, D.C., Skelly, C.L., Fortunato, J.E., Glagov, S. “Diurnal Heart Rate Reactivity: a Predictor of Severity of Experimental Coronary and Carotid atherosclerosis.” Journal of Cardiovascular Risk 9:331-8, 2002. Lee, D.C., Oz, M.C., Weinberg, A.D., Ting, W. “Appropriate Timing of Surgical Intervention after Transmural Acute Myocardial Infarction.” Journal of Thoracic and Cardiovascular Surgery 125:11520, 2003. Xu, Z., Qu, W., Lee, D.C., Schmidt, A.M. “Homo Sapiens Diaphanous mRNA” GenBank AY360322, 2003. Kavarana, M.N., Frumento, R.J., Hirsh, A.L., Oz, M.C., Lee, D.C., Bennett-Guerrero, E. “Gastric Hypercarbia and Adverse Outcome after Cardiac Surgery” Intensive Care Medicine 29:742-8, 2003. Lai, L.T., Lee, D.C., Ko, W., Shevde, K., Zhang, M. “Deficiency of complement factor MBL in a patient required cardiac surgery after an acute myocardial infarction with underlining chronic lymphocytic leukemia.” International Journal of Cardiology. 139: e24-6, 2010. Kolli, A., Au, J.T., Lee, D.C., Klinoff, N., Ko, W. “Compartment Syndrome After Endoscopic Harvest of the Great Saphenous Vein During Coronary Artery Bypass Grafting.” Annals of Thoracic Surgery 89: 271-273, 2010. Au, J.T., Sugiyama, G., Wang H, Nicastri A., Lee, D., Ko, W., Tak, V. “Carcinosarcoma of the oesophagus – a rare mixed type of tumor.” JSCR, 7:7, 2010. Hou, Y.J., Lee, D.C., Ko, W., Kim, A., Lee, J., Shevde, K., Zhang, M. “Perioperative pattern of mannan-binding lectin (MBL) may be related to the clinical outcome in patients with pre-existing MBL deficiency undergoing cardiac surgery.” Annals of Thoracic Surgery, 90: 1357-8, 2010. Sugiyama, G., Lau, C., Tak, V., Lee, D.C., Burack, J. “Traumatic Ventricular Septal Defect: Management Strategies for Penetrating Cardiac Trauma Leading to Ventricular Septal Defect.” Annals of Thoracic Surgery 91:908-10, 2011. Barbour, R.L., Graber, H.L., Xu, Y., Pei, Y., Schmitz, C.H., Pfeil, D.S., Tyagi A., Andronica, R., Lee, D.C., Barbour, S.S., Nichols, J.D., Pflieger, M.E., “A Programmable Laboratory Testbed for Evaluation of Functional Brain Activation and Connectivity.” IEEE Transactions on Neural Systems and Rehabilitation Engineering 20:170-183, 2012. Zhang, M., Hou, Y., Cavusoglu, E., Lee, D.C., Steffensen, R., Yang, L., Bashari, D., Villamil J., Moussa, M., Fernaine, G., Jensenius, J.C., Marmur, J.D., Ko, W., Shevde, K. “MASP-2 Activation is Involved in Ischemia-related Necrotic Myocardial Injury in Humans.” International Journal of Cariology, 166(2):499-504, 2013. Lee, D.C., Ramirez, S.A., Bacchetta, M., Borer, J.S., Ko, W. “Off-Pump versus On-Pump CABG in Octogenarians: Comparison of Short-Term Outcomes and Long-Term Survival.” Cardiology 125(3):164-169, 2013. 8 Graber, H.L., Pei, Y., Xu, Y., Farber, M.B., Katz, M.S., Patel, N., Solomon, W.B., Lee, D.C., Barbour, R.L. “Utility of Spontaneous and Evoked Vascular Dynamics, Assessed by Near Infrared Diffuse Optical Tomography, for Diagnosis of Breast Cancer” Accepted pending revision. Applied Optics. Ramirez, S.A., Simpson, L., Graber, H.L., Xu, Y., Pei, Y., Pfeil, D., Tak, V., Burack, J., Ko, W., Barbour, R.L., Lee, D.C. “Cerebral Monitoring in Cardiac Surgery: Influence of Sensor Density on Sensitivity of Near Infrared Spectroscopy.” Accepted pending revision. Journal of Biomedical Optics. Liu, J.Y., Lee, D.C., Ko, W. “A Comparison of the iSTAT Handheld Device with Hemochron 801 on Measurement of High Range Activated Clotting Time in Patients Undergoing Cardiopulmonary Bypass.” Accepted pending revision. Journal of ExtraCorporeal Technology. Lee, D.C., Gevorgyan, T., Pfeil, D.S., Graber, H.L., Xu, Y., Mangla, S., Barone, F.C., Libien, J., Charchaflieh, J., Kral, J.G., Ramirez, S.A., Simpson, L., Barbour, R.L. “Feasibility of Near Infrared Spectroscopic Tomography for Intraoperative Functional Cerebral Monitoring: A Primate Study.” Accepted pending revision. Journal of Thoracic and Cardiovascular Surgery. TEXTBOOK CHAPTER Uglialoro, A.D., Pfeil, D.S., Gevorgyan, T., Graber, H.L., Xu, Y., Mangla S., Barone, F.C., Libien, J., Charchaflieh, J., Kral, J.G., Ramirez, S.A., Simpson, L., Lee, D.C., Barbour, R.L. “Cerebral Monitoring and Surveillance Using High-Resolution Functional Optical Imaging.” In Schwartz, T, Ma, H., Schwarts, T.H. (ed.): Neurovascular Coupling Methods, Neuromethods, 88: 307-330. New York, Springer Science and Business Media, 2014. Lee, D.C., Ting, W., Oz, M.C. "Myocardial Revascularization after Acute Myocardial Infarction." in Cohn, L.H., Edmunds, L.H. Jr. (ed.): Cardiac Surgery in the Adult, Second Edition. New York, McGraw-Hill, 2003; p 639-58. CONFERENCE PAPERS AND ABSTRACTS Bassiouny, H.S., Lee, D.C., Zarins, C.K., Glagov, S., “Low Diurnal Heart Rate Variability Inhibits Experimental Carotid Stenosis.” The American Society for Artificial Internal Organs, May, 1995. Bassiouny, H.S., Lee, D.C., Zarins, C.K., Glagov, S., “Low Diurnal Heart Rate Variability Inhibits Experimental Carotid Stenosis.” International Conference of Cardiovascular Surgery, June, 1995. Lee, D.C., Bassiouny, H.S., Zarins, C.K., Glagov, S., “Low Diurnal Heart Rate Variability Inhibits Experimental Coronary Stenosis.” The American Heart Association, November, 1995. 9 Bassiouny, H.S., Lee, D.C., Zarins, C.K., Glagov, S., "Low Diurnal Heart Rate Variability Inhibits Experimental Carotid Stenosis.” American College of Surgeons, 1995. Bassiouny, H.S., Lee, D.C., Glagov, S., Zarins, C.K. “Heart Rate Reactivity as a Predictor of the Severity of Experimental Carotid Stenosis.” Society of Vascular Surgery, 2000. Lee, D.C., Oz, M.C., Lin, S.X., Ting, W. “Optimal Timing of Coronary Revascularization – Transmural Versus Nontransmural Acute Myocardial Infarction.” Society of Throracic Surgery, 2000. Lee, D.C., Oz, M.C., Lin, S.X., Weinberg, A.D., Ting, W. “Quality of Care and Outcome in Coronary Revascularization: Are There any Differences between Mandatory and Voluntary Reporting?” Journal of the American College of Surgeons 191:S85-86, 2000. Lee, D.C., Ting, W. “Optimal Timing of Coronary Revascularization – Transmural Versus Nontransmural Acute Myocardial Infarction.” CAMS, 2000. Kavarana, M.N., Frumento, R.J., Hirsh, A.L., Oz, M.C., Mets, B., Lee, D.C., Bennett-Guerrero, E. “Association of Sublingual PCO2, Gastric PCO2, and Adverse Outcome Following Cardiac Surgery.” American Society of Anesthesia, 2001. Lee, D.C., Oz, M.C., Weinberg, A.D., Ting, W. “Appropriate Timing of Surgical Intervention after Transmural Acute Myocardial Infarction.” American Association for Thoracic Surgery, 2001. Lee, D.C., Grimblatov, V., Avila, L., Laine, A. Heinz, T.F., Oz, M.C., Leonard, E.F. “Endoscopic Visualization through Blood.” American Society of Artificial Internal Organs, 2001. Lee, D.C., Qu, W, Lu, Y., Stern, D.M., Schmidt, A.M. “Blockade of RAGE Suppresses Growth, Metastases, and Progression of Mammary Tumors in a Murine Model of Breast Cancer.” American College of Surgeons, 2001. Bucciarelli, L.G., Wendt, T.M., Qu, W., Lu, Y., Lalla, E., Goova, M.T., Rong, L.L., Moser, B., Lee, D.C., Kashyap Y., Stern, D.M., Schmidt, A.M. "RAGE Blockade Suppresses Migration and Activation of Mononuclear Phagocytes and Vascular Smooth Muscle Cells in Diabetic Vascular Lesions: Implications for Atherosclerotic Lesion Stabilization." Keystone Symposia in Inflammatory Paradigms and the Vasculature II, 2002. Grimblatov, V., Lee, D.C., Oz, M.C., Leonard, E.F. "Spectral Analysis of Optical Imaging Through Blood." SPIE-The International Society for Optical Engineering, 2002. Lee, D.C., Frumento, R.J., Oz, M.C., Bennett-Guerrero, E. “N-Acetylcysteine and Total Plasma Antioxidant Status in High Risk Cardiac Surgical Patients.” Society of Cardiovascular Anesthesia, 2002. Lee, D.C., Xu, Z., Qu, W., Lu, Y., Anderson, D., Stern, D.M., Schimdt, A.M. “Blockade of Receptor for AGE (RAGE) Suppresses Growth and Metastases of Mammary Tumors in a Murine Model of Breast Cancer.” Proceedings of the American Association for Cancer Research 43:197, 2002. 10 Waterhouse, R.N., Fawwaz, R., Collier L., Dumont F., Lee, D.C., Schmidt A.M., Van Heertum, R. "The Sigma-1 Receptor PET Radiotracer [18F]FPS1: Potential Advantages over [18F]FDG For Tumor Visualization Demonstrated in Pre-Clinical Models." Society of Nuclear Medicine, 2002. Lee, D.C., del Toro, G., Xu, Z., Kim, J., Qu, W., Lu, Y., Stern, D.M., Schmidt, A.M. “Blockade of RAGE and Cytotoxic Chemotherapy Enhances Suppression of Experimental Metastases.” Journal of the American College of Surgeons 195:S67-68, 2002. Chiu, A.K., Ko, W., Lee, D.C. “Systemic Absorption of Topical Vancomycin Paste in Sternal Wound Infection Prophylaxis.” American College of Surgeons, 2008. Lai, L.T., Lee, D.C., Ko, W., Shevde, K., Zhang, M. “Deficiency of complement factor MBL in a patient required cardiac surgery after an acute myocardial infarction with underlining chronic lymphocytic leukemia.” Internatioanl Anesthesia Research Society. San Diego, CA, 2009. Lee, D.C. Chiu, A.K., Bacchetta, M,, Ko, W.“Off-pump versus On-pump CABG in Octogenarians: Comparison of Short Term Outcomes and Long Term Survival.” New York Surgical Society, 2009. Lee, D.C., Ramirez, S., Simpson, L., Graber, H.L., Xu, Y., Pei, Y., Pfeil, D.S., Tak, V., Burack, J., Barbour, R.L. “Cerebral Monitoring in Cardiac Surgery with Near-Infrared Spectroscopic (NIRS) Diffuse Optical Tomography (DOT).” Paper NIH01-102. The Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside. Bethesda, MD, 2009. Barbour, R.L., Graber, H.L., Pei, Y., Xu, Y., Lee, D.C., Katz, M.S., Patel, N., Jagarlamudi, K., Nwanguma, O.R., Solomon, W.B. “Derivation and validation of metrics for breast cancer screening from diffuse optical tomography imaging data.” Paper NIH01-103. The Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside. Bethesda, MD, 2009. Graber, H.L., Barbour, R.L., Pei, Y., Xu, Y., Lee, D.C., Katz, M.S., Patel, N., Jagarlamudi, K., Nwanguma, O.R., Solomon, W.B. “Diagnostic predictors of breast cancer derived from diffuse optical tomography image time series correlate with subject demographic and tumor phenotype data.” Paper NIH01-104. The Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside. Bethesda, MD, 2009. Lee, D.C., Carter, T., Tak, V.M., Terry, P.G., Ko, W. “On-Pump Beating-Heart Coronary Revascularization in Acute Myocardial Infarction Complicated by Cardiogenic Shock.” CAMS 2009. Terry, P., Siu, S., Salak, K., Lee, D., Tak, V., Kamran, H., Ko, W. “Efficacy of a nurse driven multidisciplinary protocol for transition from intravenous to subcutaneous insulin after cardiac surgery.” Canadian Journal of Diabetes 2009;33(3)288. Zhang, M., Hou, Y., Gulaya, K., Lee, D.C., Lee, J., Rushbrook, J., Shevde, K. “Significant Correlation between Complement Factor B and Myocardial Injury in Patients Undergoing Cardiac Surgery.” Paper 557. International Anesthesia Research Society. Honolulu, HI, 2010. Hou, Y., Lee, D.C., Ko, W., Shevde, K., Zhang, M., "Perioperative pattern of inflammatory marker mannose-binding lectin (MBL) may be related to clinical outcome in patients with pre-existing MBL deficiency undergoing open heart surgery" Paper 583. International Anesthesia Research Society. Honolulu, HI, 2010. 11 Carter, T., Lee, D.C,, Tak, V.M., Terry, P.G., Ko, W. “On-Pump Beating-Heart Coronary Revascularization in Acute Myocardial Infarction Complicated by Cardiogenic Shock.” New York Surgical Society 2010. Ramirez, S.A., Simpson, L., Graber, H.L., Xu, Y., Pei, Y., Pfeil, D., Tak, V.,Burack, J.,Ko, W., Barbour, R.L., Lee, D.C. “Do Low-density Cerebral Oximetry Measures Accurately Detect Variability of Cerebral Perfusion During Cardiac Surgery?” Paper JMA 100. OSA Topical Meetings at The Biomedical Optics and 3-D Imaging: OSA Optics and Photonic Congress (Miami, FL, April 11-14, 2010). Terry, P., Siu, S., Salak, K., Lee, D., Tak, V., Kamran, H., Ko, W. “A multidisciplinary protocol specifying a basal/bolus regimen of subcutaneous insulin in transition from continuous insulin infusion for glycemic control in cardiac surgery patients.” AACE (American Association of Clinical Endocrinologists) 19th Annual Meeting and Clinical Congress (April, 2010, Boston, MA). Zhang, M., Hou, Y., Gulaya, K., Lee, D., Lee, J., Rushbrook, J., Shevde, K. “Early complement activation through alternative pathway significantly correlates to myocardial injury in patients undergoing cardiac surgery.” Journal of Immunology. 2010;184(142):6. Ramirez, S.A., Simpson, L., Graber, H.L., Xu, Y., Pei, Y., Pfeil, D., Tak, V.,Burack, J.,Ko, W., Barbour, R.L., Lee, D.C. “Cerebral Monitoring in Cardiac Surgery: Sensitivity of Hb co-variations and individual components.” Paper 3898, 16th Annual Meeting of the Organization for Human Brain Mapping (Barcelona, Spain, June 6-10, 2010). Ramirez, S.A., Simpson, L., Graber,H.L., Xu, Y., Pei, Y., Pfeil, D., Tak, V., Burack, J., Ko, W., Barbour, R.L., Lee, D.C. "Cerebral oximetry neglects variability of cerebral perfusion during cardiac surgery," Paper 3503, 16th Annual Meeting of the Organization for Human Brain Mapping (Barcelona, Spain, June 6-10, 2010). Zhang, M., Hou, Y., Cavusoglu, E., Lee, D., Steffensen, R., Yang, L., Jensenius, J.C., Marmur J., Schwaeble, W., Ko, W., Shevde, K. “Complement Factor MASP-2 is activated after acute myocardial ischemia in human.” Journal of Immunology. 2011;186 (116):28. Barbour, R.L., Graber, H.L., Schmitz, C.H., Pfeil, D.S., Lee, D.C., Xu, Y. "An experimental platform for dynamic causal modeling-based analysis of functional neuroimaging data." Paper 511 at the 17th Annual Meeting of the Organization for Human Brain Mapping (Québec City, Canada, June 26-30, 2011). McNiel, D.B., Barbour, R.L., Lee, D.C., Kim, R.M. "Examination of necrotizing enterocolitis in preterm infants using diffuse optical tomography," Paper NIH100-99 at the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside (Bethesda, MD, September 15-16, 2011). Xu, Y., Pfeil, D.S., Gevorgyan, T., Lee, D.C., Barbour, R.L. "3D DOT Brain Imaging for Rhesus Monkey: An Anatomical Atlas-Based Method." Paper NIH100-55 at the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside (Bethesda, MD, September 15-16, 2011). 12 Pfeil, D.S., Ramirez, S.A., Simpson, L., Graber, H.L., Stefanov, D., Xu, Y., Tak, V.M., Burack, J.H., Gevorgyan, T., Barbour, R.L., Lee, D.C. "Blood Pressure-Related Hemodynamic Shifts in the Cerebral Cortex During Cardiac Surgery." Paper NIH100-54 at the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside (Bethesda, MD, September 15-16, 2011). Gevorgyan, T., Pfeil, D.S., Graber, H.L., Xu, Y., Mangla, S., Barone, F.C., Charchaflieh, J., Barbour, R.L., Lee, D.C. "Cerebral monitoring during acute stroke and subarachnoid hemorrhage in the Bonnet Macaque with functional near infrared spectroscopy (fNIRS)." Paper NIH100-52 at the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside (Bethesda, MD, September 15-16, 2011). Graber, H.L., Barbour, R.L., Schmitz, C.H., Lee, D.C., Xu, Y. "An Experimental Testbed for Optimization of Data Collection and Analysis in NIRS Functional Neuroimaging." Paper NIH100-49 at the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside (Bethesda, MD, September 15-16, 2011). Lee, D.C., Ramirez, S.A., Borer, J., Ko, W. “Off-pump versus On-pump CABG in Octogenarians: Comparison of Short Term Outcomes and Long Term Survival.” American College of Surgeons, 2011. Pfeil, D.S., Ramirez, S.A., Simpson, L., Graber,H.L., Xu, Y., Pei, Y., Tak, V., Burack, J., Ko, W., Barbour, R.L., Lee, D.C. "Cerebral Oximetry in Cardiac Surgery: Exploration of Regional Variability.” Journal of the American College of Surgeons 213(3):S47-8, 2011. Gevorgyan, T., Pfeil, D.S., Graber, H.L., Xu, Y., Mangla, S., Barone, F.C., Libien, J., Charchaflieh, J., Barbour, R.L., Lee, D.C. “Histopathological and Radiological Validation of Continuous Wave (CW) Near Infrared Spectroscopy (NIRS) Recordings During Cerebral Intravascular Manipulations.” Paper BS4A.4, 2012 OSA Optics and Photonics Congress: Biomedical Optics and 3-D Imaging. Barbour, R.L., Graber, H.L., Xu, Y., Pei, Y., Schmitz, C., Pfeil, D.S., Tyagi, A., Andronica, R., Lee, D.C., Barbour, S., Nichols, J., Pfliefer, M. “A Programmable Testbed in Support of Evaluation of Functional Brain Activation.” Paper BT3A.94, 2012 OSA Optics and Photonics Congress: Biomedical Optics and 3-D Imaging. Xu, Y., Gevorgyan, T., Pfeil, D.S., Lee, D.C., Barbour, R.L. “An Anatomical Atlas-Based Method for fNIRS Imaging of the Rhesus Macaque.” Paper BT3A.89, 2012 OSA Optics and Photonics Congress: Biomedical Optics and 3-D Imaging. Carter, T.I., Lee, D.C., Tak, V.M., Burack, J.H., Ko, W. “On-Pump Beating-Heart Coronary Artery Bypass Surgery in Acute Myocardial Infarction Complicated by Cardiogenic Shock.” Journal of the American College of Surgeons 215(3):S43-44, 2012. Gevorgyan, T., Graber,H.L., Pfeil, D.S., Mangla, S., Barone, F.C., Libien, J., Charchaflieh, J. Kral, J.G., Barbour, R.L., Lee, D.C. “Near Infrared Spectroscopic Tomography for Cerebral Monitoring of Stroke and Intracranial Hemorrhage.” Journal of the American College of Surgeons 215(3):S59-60, 2012 13 Gevorgyan, T., Graber, H.L., Pfeil, D.S., Xu, Y., Mangla, S., Barone, F.C., Libien, J., Charchaflieh, J., Kral, J., Barbour, R.L., Lee, D.C. “Concurrence of Significant Cerebrovascular Events with fNIRS and CT, MRI, and Histopathology.” In Press, Anesthesia and Analgesia. Barbour, R.L., Graber, H.L., Xu, Y., Pei, Y., Schmitz, C., Pfeil, D.S., Tyagi, A., Andronica, R., Lee, D.C., Barbour, S., Nichols, J., Pfliefer, M. “A Programmable Testbed in Support of Evaluation of Functional Brain Activation.” Paper 732, 18th Annual Meeting of the Organization for Human Brain Mapping, 2012. Gevorgyan, T., Pfeil, D.S., Graber, H.L., Xu, Y., Mangla, S., Barone, F.C., Libien, J., Charchaflieh, J., Kral, J.G., Ramirez, S.A., Simpson, L., Barbour, R.L., Lee, D.C. “Feasibility of Near Infrared Spectroscopic Tomography for Intraoperative Functional Cerebral Monitoring: A Primate Study.” Proceedings of the American Association for Thoracic Surgery,F2:184-185, 2014. PRESENTATIONS Lee, D.C., Rodriguez, E.K., McCulloch, A.D. "Effect of Residual Stress on Transmural Sarcomere Length Distrubutions in Rat Left Ventricle." University of California at San Diego Research Conference, May, 1992. Lee, D.C., Bassiouny, H.S. “Diurnal Heart Rate Variability and Experimental Carotid Atherosclerosis.” University of Chicago Pritzker Research Forum, October, 1994. Bassiouny, H.S., Lee, D.C., Zarins, C.K., Glagov, S. “Low Diurnal Heart Rate Variability Inhibits Experimental Carotid Stenosis.” Society for Vascular Surgery/North American Chapter, International Society for Cardiovascular Surgery, June 11, 1995. Bassiouny, H.S., Lee, D.C., Zarins, C.K., Glagov, S. “Low Diurnal Heart Rate Variability Inhibits Experimental Carotid Stenosis.” American College of Surgeons, 1995. Bassiouny, H.S., Lee, D.C., Glagov, S., Zarins, C.K. “Heart Rate Reactivity as a Predictor of the Severity of Experimental Carotid Stenosis.” Society of Vascular Surgery, 2000. Lee, D.C., Oz, M.C., Lin, S.X., Ting, W. “Optimal Timing of Coronary Revascularization – Transmural Versus Nontransmural Acute Myocardial Infarction.” Society of Throracic Surgery, 2000. Lee, D.C., Oz, M.C., Lin, S.X., Weinberg, A.D., Ting, W. “Quality of Care and Outcome in Coronary Revascularization: Are There any Differences between Mandatory and Voluntary Reporting?” American College of Surgeons, 2000. Lee, D.C., Ting, W. “Optimal Timing of Coronary Revascularization – Transmural Versus Nontransmural Acute Myocardial Infarction.” CAMS Scientific Session, 2000. 14 Kavarana, M.N., Frumento, R.J., Hirsh, A.L., Oz, M.C., Mets, B., Lee, D.C., Bennett-Guerrero, E. “Association of Sublingual PCO2, Gastric PCO2, and Adverse Outcome Following Cardiac Surgery.” American Society of Anesthesia, 2001. Lee, D.C., Oz, M.C., Weinberg, A.D., Ting, W. “Appropriate Timing of Surgical Intervention after Transmural Acute Myocardial Infarction.” American Association for Thoracic Surgery, 2001. Lee, D.C., Grimblatov, V., Avila, L., Laine, A. Heinz, T.F., Oz, M.C., Leonard, E.F. “Endoscopic Visualization through Blood.” American Society for Artificial Internal Organs, 2001. Lee, D.C., Qu, W, Lu, Y., Stern, D.M., Schmidt, A.M. “Blockade of RAGE Suppresses Growth, Metastases, and Progression of Mammary Tumors in a Murine Model of Breast Cancer.” American College of Surgeons, 2001. Bucciarelli, L.G., Wendt, T.M., Qu, W., Lu, Y., Lalla, E., Goova, M.T., Rong, L.L., Moser, B., Lee, D.C., Kashyap Y., Stern, D.M., Schmidt, A.M. "RAGE Blockade Suppresses Migration and Activation of Mononuclear Phagocytes and Vascular Smooth Muscle Cells in Diabetic Vascular Lesions: Implications for Atherosclerotic Lesion Stabilization." Keystone Symposia in Inflammatory Paradigms and the Vasculature II, 2002. Grimblatov, V., Lee, D.C., Oz, M.C., Leonard, E.F. "Spectral Analysis of Optical Imaging Through Blood." SPIE-The International Society for Optical Engineering, 2002. Lee, D.C., Frumento, R.J., Oz, M.C., Bennett-Guerrero, E. “N-Acetylcysteine and Total Plasma Antioxidant Status in High Risk Cardiac Surgical Patients.” Society of Cardiovascular Anesthesia, 2002. Lee, D.C., Xu, Z., Qu, W., Lu, Y., Anderson, D., Stern, D.M., Schimdt, A.M. “Blockade of Receptor for AGE (RAGE) Suppresses Growth and Metastases of Mammary Tumors in a Murine Model of Breast Cancer.” American Association for Cancer Research, 2002. Waterhouse, R.N., Fawwaz, R., Collier L., Dumont F., Lee, D.C., Schmidt A.M., Van Heertum, R. "The Sigma-1 Receptor PET Radiotracer [18F]FPS1: Potential Advantages over [18F]FDG For Tumor Visualization Demonstrated in Pre-Clinical Models." Society of Nuclear Medicine, 2002. Lee, D.C., del Toro, G., Xu, Z., Kim, J., Qu, W., Lu, Y., Stern, D.M., Schmidt, A.M. “Blockade of RAGE and Cytotoxic Chemotherapy Enhances Suppression of Experimental Metastases.” American College of Surgeons, 2002. Lee, D.C.“Coronary Artery Bypass Grafting in Acute Myocardial Infarction.” Yale University School of Medicine Department of Surgery Grand Rounds, 2005. Chiu, A.K., Ko, W., Bacchetta, M, Lee, D.C. “Off-pump versus On-pump CABG in Octogenarians: Comparison of Short Term Outcomes and Long Term Survival.” State University of New York Downstate Medical Center Research Conference, 2008. Lai, L.T., Lee, D.C., Ko, W., Shevde, K., Zhang, M. “Deficiency of complement factor MBL in a patient required cardiac surgery after an acute myocardial infarction with underlining chronic lymphocytic leukemia.” State University of New York Downstate Medical Center Research Conference, 2008. 15 Chiu, A.K., Ko, W., Lee, D.C. “Systemic Absorption of Topical Vancomycin Paste in Sternal Wound Infection Prophylaxis.” American College of Surgeons. 2008. Lai, L.T., Lee, D.C., Ko, W., Shevde, K., Zhang, M. “Deficiency of complement factor MBL in a patient required cardiac surgery after an acute myocardial infarction with underlining chronic lymphocytic leukemia.” Internatioanl Anesthesia Research Society. San Diego, CA, 2009. Lee, D.C. Chiu, A.K., Bacchetta, M,, Ko, W.“Off-pump versus On-pump CABG in Octogenarians: Comparison of Short Term Outcomes and Long Term Survival.” New York Surgical Society, 2009. Pfeil, D. Blanton, E., Ko, W., Graber,H.L., Barbour, R.L., Lee, D.C. “NIRS Tomography and Cerebral Monitoring in Cardiac Surgery.” State University of New York Downstate Medical Center Research Conference, 2009. Hou, Y.J., Lee, D.C., Ko, W., Shevde, K., Zhang, M. “Concurrent change of the levels of inflammatory factors Mannose-binding lectin (MBL) and C-reactive protein (CRP) in a patient with pre-existing MBL deficiency undergoing coronary artery bypass grafting (CABG).” State University of New York Downstate Medical Center Research Conference, 2009. Lee, D.C. “Neurocognitive Dysfunction and Cerebral Perfusion in Cardiac Surgery.” State University of New York Downstate Medical Center Division of Cardiothoracic Surgery Grand Rounds. 2009. Lee, D.C., Ramirez, S., Simpson, L., Graber, H.L., Xu, Y., Pei, Y., Pfeil, D.S., Tak, V., Burack, J., Barbour, R.L. “Cerebral Monitoring in Cardiac Surgery with Near-Infrared Spectroscopic (NIRS) Diffuse Optical Tomography (DOT).” Paper NIH01-102. The Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside. Bethesda, MD, 2009. Barbour, R.L., Graber, H.L., Pei, Y., Xu, Y., Lee, D.C., Katz, M.S., Patel, N., Jagarlamudi, K., Nwanguma, O.R., Solomon, W.B. “Derivation and validation of metrics for breast cancer screening from diffuse optical tomography imaging data.” Paper NIH01-103. The Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside. Bethesda, MD, 2009. Graber, H.L., Barbour, R.L., Pei, Y., Xu, Y., Lee, D.C., Katz, M.S., Patel, N., Jagarlamudi, K., Nwanguma, O.R., Solomon, W.B. “Diagnostic predictors of breast cancer derived from diffuse optical tomography image time series correlate with subject demographic and tumor phenotype data.” Paper NIH01-104. The Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside. Bethesda, MD, 2009. Lee, D.C., Carter, T., Tak, V.M., Terry, P.G., Ko, W. “On-Pump Beating-Heart Coronary Revascularization in Acute Myocardial Infarction Complicated by Cardiogenic Shock.” CAMS Scientific Session, 2009. Terry, P., Siu, S., Salak, K., Lee, D., Tak, V., Kamran, H., Ko, W. “Efficacy of a nurse driven multidisciplinary protocol for transition from intravenous to subcutaneous insulin after cardiac surgery.” International Diabetes Federation 20th World Diabetes Congress, Montreal, Canada, 2009. Zhang, M., Hou, Y., Gulaya, K., Lee, D.C., Lee, J., Rushbrook, J., Shevde, K. “Significant Correlation between Complement Factor B and Myocardial Injury in Patients Undergoing Cardiac Surgery.” International Anesthesia Research Society. Honolulu, HI, 2010. 16 Hou, Y., Lee, D.C., Ko, W., Shevde, K., Zhang, M., "Perioperative pattern of inflammatory marker mannose-binding lectin (MBL) may be related to clinical outcome in patients with pre-existing MBL deficiency undergoing open heart surgery." International Anesthesia Research Society. Honolulu, HI, 2010. Carter, T., Lee, D.C,, Tak, V.M., Terry, P.G., Ko, W. “On-Pump Beating-Heart Coronary Revascularization in Acute Myocardial Infarction Complicated by Cardiogenic Shock.” New York Surgical Society 2010. Ramirez, S.A., Graber, H.L., Simpson, L., Xu, Y., Pei, Y., Pfeil, D.S., Tak, V., Burack, J., Ko, W., Barbour, R.L., Lee, D.C. “Cerebral Monitoring Using Individual Components and Co-variations in a High Density Array During Cardiac Surgery.” State University of New York Downstate Medical Center Research Conference, 2010. Ramirez, S.A., Simpson, L., Graber, H.L., Xu, Y., Pei, Y., Pfeil, D.S., Tak, V., Burack, J., Ko, W., Barbour, R.L., Lee, D.C., “Variability of Cerebral Perfusion During Cardiac Surgery Impedes Monitoring Capabilities of Cerebral Oximetry. State University of New York Downstate Medical Center Research Conference, 2010. Simpson, L., Ramirez, S.A., Lee, D.C., Tak, V., Burack, J. “Diagnostic Yield of Subxiphoid Pericardial Biopsy vs. Pericadiocetesis with Cytology for Patients Presenting with Pericardial Effusion or Tamponade.” State University of New York, Downstate Medical Center Research Conference, 2010. Ramirez, S.A., Simpson, L., Graber, H.L., Xu, Y., Pei, Y., Pfeil, D., Tak, V.,Burack, J.,Ko, W., Barbour, R.L., Lee, D.C. “Do Low-density Cerebral Oximetry Measures Accurately Detect Variability of Cerebral Perfusion During Cardiac Surgery?” Paper JMA 100. OSA Topical Meetings at The Biomedical Optics and 3-D Imaging: OSA Optics and Photonic Congress (Miami, FL, April 11-14, 2010). Terry, P., Siu, S., Salak, K., Lee, D., Tak, V., Kamran, H., Ko, W. “A multidisciplinary protocol specifying a basal/bolus regimen of subcutaneous insulin in transition from continuous insulin infusion for glycemic control in cardiac surgery patients.” AACE (American Association of Clinical Endocrinologists) 19th Annual Meeting and Clinical Congress (April 2010, Boston, MA) Zhang, M., Hou, Y., Gulaya, K., Lee, D., Lee, J., Rushbrook, J., Shevde, K. “Early complement activation through alternative pathway significantly correlates to myocardial injury in patients undergoing cardiac surgery.” American Association of Immunologists, 2010. Ramirez, S.A., Simpson, L., Graber, H.L., Xu, Y., Pei, Y., Pfeil, D., Tak, V.,Burack, J.,Ko, W., Barbour, R.L., Lee, D.C. “Cerebral Monitoring in Cardiac Surgery: Sensitivity of Hb co-variations and individual components.” 16th Annual Meeting of the Organization for Human Brain Mapping (Barcelona, Spain, June 6-10, 2010). Ramirez, S.A., Simpson, L., Graber,H.L., Xu, Y., Pei, Y., Pfeil, D., Tak, V., Burack, J., Ko, W., Barbour, R.L., Lee, D.C. "Cerebral oximetry neglects variability of cerebral perfusion during cardiac surgery," Poster 861 MT-AM at the 16th Annual Meeting of the Organization for Human Brain Mapping (Barcelona, Spain, June 6-10, 2010). 17 Lee, D.C.“Coronary Artery Bypass Grafting in Acute Myocardial Infarction.” State University of New York Downstate Medical Center Division of Cardiothoracic Surgery Grand Rounds. 2010. Pfeil, D.S., Ramirez, S.A., Graber, H.L., Simpson, L., Xu, Y., Pei, Y., Tak, V., Burack, J., Ko, W., Barbour, R.L., Lee, D.C. “Blood Pressure Related Hemodynamic Shifts in the Cerebral Cortex During Cardiothoracic Surgery.” State University of New York, Downstate Medical Center Research Conference, 2011. Zhang, M., Hou, Y., Cavusoglu, E., Lee, D., Steffensen, R., Yang, L., Jensenius, J.C., Marmur J., Schwaeble, W., Ko, W., Shevde, K. “Complement Factor MASP-2 is activated after acute myocardial ischemia in human.” American Association of Immunologists (San Francisco, CA, May 13-17). Barbour, R.L., Graber, H.L., Schmitz, C.H., Pfeil, D.S., Lee, D.C., Xu, Y. "An experimental platform for dynamic causal modeling-based analysis of functional neuroimaging data." Paper 511 at the 17th Annual Meeting of the Organization for Human Brain Mapping (Québec City, Canada, June 26-30, 2011). McNiel, D.B., Barbour, R.L., Lee, D.C., Kim, R.M. "Examination of necrotizing enterocolitis in preterm infants using diffuse optical tomography," Paper NIH100-99 at the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside (Bethesda, MD, September 15-16, 2011). Xu, Y., Pfeil, D.S., Gevorgyan, T., Lee, D.C., Barbour, R.L. "3D DOT Brain Imaging for Rhesus Monkey: An Anatomical Atlas-Based Method." Paper NIH100-55 at the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside (Bethesda, MD, September 15-16, 2011). Pfeil, D.S., Ramirez, S.A., Simpson, L., Graber, H.L., Stefanov, D., Xu, Y., Tak, V.M., Burack, J.H., Gevorgyan, T., Barbour, R.L., Lee, D.C. "Blood Pressure-Related Hemodynamic Shifts in the Cerebral Cortex During Cardiac Surgery." Paper NIH100-54 at the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside (Bethesda, MD, September 15-16, 2011). Gevorgyan, T., Pfeil, D.S., Graber, H.L., Xu, Y., Mangla, S., Barone, F.C., Charchaflieh, J., Barbour, R.L., Lee, D.C. "Cerebral monitoring during acute stroke and subarachnoid hemorrhage in the Bonnet Macaque with functional near infrared spectroscopy (fNIRS)." Paper NIH100-52 at the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside (Bethesda, MD, September 15-16, 2011). Graber, H.L., Barbour, R.L., Schmitz, C.H., Lee, D.C., Xu, Y. "An Experimental Testbed for Optimization of Data Collection and Analysis in NIRS Functional Neuroimaging." Paper NIH100-49 at the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside (Bethesda, MD, September 15-16, 2011). Lee, D.C., Ramirez, S.A., Borer, J., Ko, W. “Off-pump versus On-pump CABG in Octogenarians: Comparison of Short Term Outcomes and Long Term Survival.” American College of Surgeons, 2011. 18 Pfeil, D.S., Ramirez, S.A., Simpson, L., Graber,H.L., Xu, Y., Pei, Y., Tak, V., Burack, J., Ko, W., Barbour, R.L., Lee, D.C. "Cerebral Oximetry in Cardiac Surgery: Exploration of Regional Variability.” American College of Surgeons, 2011. Gevorgyan, T., Pfeil, D.S., Graber, H.L., Xu, Y., Mangla, S., Barone, F.C., Libien, J., Charchaflieh, J., Barbour, R.L., Lee, D.C. “Histopathological and Radiological Validation of Continuous Wave (CW) Near Infrared Spectroscopy (NIRS) Recordings During Cerebral Intravascular Manipulations.” Paper BS4A.4, 2012 OSA Optics and Photonics Congress: Biomedical Optics and 3-D Imaging. Miami, FL. Barbour, R.L., Graber, H.L., Xu, Y., Pei, Y., Schmitz, C., Pfeil, D.S., Tyagi, A., Andronica, R., Lee, D.C., Barbour, S., Nichols, J., Pfliefer, M. “A Programmable Testbed in Support of Evaluation of Functional Brain Activation.” Paper BT3A.94, 2012 OSA Optics and Photonics Congress: Biomedical Optics and 3-D Imaging. Miami, FL. Xu, Y., Gevorgyan, T., Pfeil, D.S., Lee, D.C., Barbour, R.L. “An Anatomical Atlas-Based Method for fNIRS Imaging of the Rhesus Macaque.” Paper BT3A.89, 2012 OSA Optics and Photonics Congress: Biomedical Optics and 3-D Imaging. Miami, FL. Carter, T.I., Lee, D.C., Tak, V.M., Burack, J.H., Ko, W. “On-Pump Beating-Heart Coronary Artery Bypass Surgery in Acute Myocardial Infarction Complicated by Cardiogenic Shock.” American College of Surgeons, 2012. Gevorgyan, T., Graber,H.L., Pfeil, D.S., Mangla, S., Barone, F.C., Libien, J., Charchaflieh, J. Kral, J.G., Barbour, R.L., Lee, D.C. “Near Infrared Spectroscopic Tomography for Cerebral Monitoring of Stroke and Intracranial Hemorrhage.” American College of Surgeons, 2012. Barbour, R.L., Graber, H.L., Xu, Y., Pei, Y., Schmitz, C., Pfeil, D.S., Tyagi, A., Andronica, R., Lee, D.C., Barbour, S., Nichols, J., Pfliefer, M. “A Programmable Testbed in Support of Evaluation of Functional Brain Activation.” Paper 732, 18th Annual Meeting of the Organization for Human Brain Mapping, 2012. Gevorgyan, T., Graber, H.L., Pfeil, D.S., Xu, Y., Mangla, S., Barone, F.C., Libien, J., Charchaflieh, J., Kral, J., Barbour, R.L., Lee, D.C. “Concurrence of Significant Cerebrovascular Events with fNIRS and CT, MRI, and Histopathology.” International Symposium on Innovations and Applications of Monitoring Perfusion, Oxygenation and Ventilation at Yale University, 2012. Lee, D.C., Gevorgyan, T., Pfeil, D.S., Graber, H.L., Xu, Y., Mangla, S., Barone, F.C., Libien, J., Charchaflieh, J., Kral, J.G., Ramirez, S.A., Simpson, L., Barbour, R.L. “Feasibility of Near Infrared Spectroscopic Tomography for Intraoperative Functional Cerebral Monitoring: A Primate Study.”, Paper F2, 94th Annual Meeting of the American Association for Thoracic Surgery, 2014. 19