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UNIVERSITÄTSKLINIKUM FREIBURG Institut für Umweltmedizin und Krankenhaushygiene Breisacher Str. 115 b, 79106 Freiburg Institut für Umweltmedizin und Krankenhaushygiene Institute of Environmental Health Sciences Ärztlicher Leiter: Prof. Dr. med. V. Mersch-Sundermann Exosomen und Tumorbiologie PD Dr. rer. nat. Irina Nazarenko Tel.: +49 761 270-82100 Fax: +49 761 270-82530 E-Mail: [email protected] Freiburg, September .2015 Medical projects in experimental cancer research in 2016/2017 Exosomes as carriers of activated oncogenes and their potential application as a diagnostic and prognostic tool during cancer therapy Our group is interested in exosomes: their function in carcinogenesis and their application as a new, non-invasive tool for cancer diagnosis and prognosis. http://www.uniklinik-freiburg.de/iuk/forschung/ exosomen-und-tumorbiologie.html. Extracellular membrane vesicles (exosomes) are physiologically involved in the horizontal transfer of nucleid acids. They play an important role in diverse physiological and pathological processes, such as regulation of immune response, blood coagulation and tumor growth. Exosomes isolated from patient plasma, ascites and other body fluids will be analysed. The project aims at detection of known biomarkers as well as identification of potentially new candidate markers in order to improve early diagnosis and prognosis in cancer. The work will be carried out in close cooperation with clinical departments. We plan to expand on existing cooperation by contributing to international projects focussing on the development of new techniques to detect exosomes. Qualification: Prospective candidates should be students of medicine and be interested in experimental cancer research. Solid knowledge of cell and molecular biology is of benefit. We expect highly motivated candidates interested in fundamental and applied research, who possess the ability to work independently and in a team. We offer highly qualified supervision, a challenging project on the frontiers of research and technology, work in a young, dynamic team, and cooperation with partners in Freiburg, Europe and word-wide. Please send your application to the group leader PD Dr. Irina Nazarenko’s PA Ms Susanne Görner, [email protected], Tel. 0049 761-270 82 550 Universitätsklinikum Freiburg, Anstalt des öffentlichen Rechts, Sitz Freiburg Aufsichtsrat Clemens Benz (Vorsitzender) Vorstand Univ.-Prof. Dr. Dr. h.c. J. R. Siewert (Vorsitz), Leitender Ärztlicher Direktor Prof. Dr. Dr. Rainer Schmelzeisen, Stellvertretender Leitender Ärztlicher Direktor Kaufmännischer Direktor: Dipl.-Verwaltungswirt Bernd Sahner Prof. Dr. K. Kriglstein, Dekanin Helmut Schiffer, Pflegedirektor Bank Sparkasse Freiburg-Nördlicher Breisgau BLZ 680 501 01 / Konto-Nr. 2004 406 IBAN DE08 6805 0101 0002 0044 06 / BIC FRSPDE66 Internet www.uniklinik-freiburg.de