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Vaginal Discharge Vaginal discharge is a combination of fluid, cells and bacteria continuously shedding; this can be normal. Abnormal vaginal discharge can represent an overgrowth of normal vaginal bacteria, a sexually transmitted disease, cancer or an anatomical abnormality. An evaluation may be necessary if discharge is thick or odorous. Also if you have pain, itching, and/or bleeding that is not part of your normal menses, an appointment may be warranted.