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HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Your day-by-day guide to ASCO 30 May - 3 June 2008 McCormick Place Chicago, IL, USA 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Contents Congress details 2 Dining 3 Safety 4 Congress site plan 6 Floor plans 8 Key 11 Saturday 31 May 12 Sunday 1 June 14 Monday 2 June 17 Tuesday 3 June 20 Hotels 22 Map 23 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Congress details Congress venue McCormick Place 2301 South Lake Shore Drive Chicago, IL 60616, USA Tel: 312 791 7000; Fax: 312 791 6543 Congress registration Location: Lakeside Center, Hall E, McCormick Place Friday 30 May: Onsite registration opens (including self-registration) Tuesday 3 June: Onsite registration closes Congress dates and opening hours 2 Friday 30 May 13:00-18:00 Saturday 31 May 08:00-18:00 Sunday 1 June 08:00-18:00 Monday 2 June 08:00-18:00 Tuesday 3 June 08:00-13:00 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Dining Recommended restaurants Blue Water Grill (American Contemporary) 520 North Dearborn Street at Grand Avenue, Chicago, IL 60610 Tel: 312 777 1400 Capital Grille (American Steakhouse) 633 North St Clair Street, Chicago, IL 60611 Tel: 312 337 9400 Catch 35 (Seafood) 35 West Wacker Drive, Chicago, IL 60601 Tel: 312 346 3500 Coco Pazzo (Italian) 300 West Hubbard Street, Chicago, IL 60610 Tel: 312 836 0900 Everest Restaurant (American Contemporary) 440 South La Salle Street, 40th Floor, Chicago, IL 60605 Tel: 312 663 8920 McCormick & Schmick’s (Seafood) 1 East Wacker Drive, Chicago, IL 60601 Tel: 312 923 7226 Morton’s (Steak and Seafood) 65 East Wacker Place, Chicago, IL 60601 Tel: 312 201 0410 N9NE Steak House (American Steakhouse) 440 West Randolph Street, Chicago, IL 60606 Tel: 312 575 9900 Ruth’s Chris Steak House (American Steakhouse) 431 North Dearborn Street, Chicago, IL 60610 Tel: 312 321 2725 Santorini (Greek) 800 West Adams Street, Chicago, IL 60661 Tel: 312 829 8820 Smith & Wollensky (American Steakhouse) 318 North State Street, Chicago, IL 60610 Tel: 312 670 9900 The Palm (Steak, Seafood and Italian) 323 East Wacker Drive, Chicago IL 60601 Tel: 312 616 1000 3 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Safety Safety tips On leaving the congress site you are advised to remove your ASCO name badge or any Roche identity insignia Keep jewellery or accessories to a minimum and do not display cameras or bags that can draw attention Keep your wallet or precious belongings in your inside front pocket or wear your handbag across your shoulders Sightsee on well-lit, well-travelled streets and passages either with a colleague or in a group Important telephone numbers Emergency services (Police, Ambulance, Fire): 911 Non-emergency services (Police and City Services): 311 Yellow Cab Chicago: 312 8294 222 Chicago Office of Tourism: 312 744 2400 4 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner 5 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner 16/5/08 Congress site plan Lakeside Center (East Building) LE V LE LE LE VE VE VE EL 4 LAKESIDE BALLROOM E354 L3 Halls D Hall E L2 L1 Office 1a LE LE North Building VE VE VE L3 L2 L1 SK YB RID s R o o m 45 1 E 45 0s m o R o 35 3 E 35 0s m o o R 27 2 E 25 0- ms Roo -5 05 S5 0 1 s m o o R -4 0 6 S4 0 1 EL 3 LE V 4 EL LEV GE s ES LAK LE nd D2 LEVEL 2 Roche bus transfer gate: 38 Arie Crown Theater Restaurant HOR E DR IVE ms R o o 6 - 4 27 N42 ms Roo 6-231 N22 ms Roo 6-14 0 N12 2 d C2 nd B 1 an B1 a alls C H r Halls o f CK level TRA ance AD Entr O C2 R d n IL a RA s C1 Hall TRA ME HYATT REGENCY McCORMICK PLACE HOTEL LEV GR EL AN 2.5 DC ON CO UR SE LEVEL 2.5 Food Court/ Restaurant Business Center METRA Entrance LEVEL 2 Restaurants MA IN RT TH LU ER KI N .D JR G, R IV LEV EXISTING GARAGE STRUCTURE & CONFERENCE CENTER CE 6 E RM LEV LEV LEV AK RO AD LEV HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner South Building Vista Room S406 A2 d 1 an LEVE L LE V E L 0 ls A S10 Hal om allro B nd Gra 3 2.5 LEVE L 1 SK YB RI D G ms R o o1 - 1 0 6 S10 476 -W 470 W s om Ro E LEVEL 2.5 Food Court/ Restaurant IVE West Building 196 LE V LE V R LE V LE V LE V D EL 5 EL 4 EL 3 EL 2 EL 1 n rde 75 Ga W3 op t s f om o m o r o l l Ro o Ba gR UE nd etin EN Gra AV Me ; 2 A F F1, IAN lls IND Ha s om g etin Me Ro -W 175 sW m o Ro LEVEL 2 Food Court/ Restaurant Business Center Gift Shops 7 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Floor plans Level 4 Meeting Rooms (E450–E451) Level 3 Exhibition Halls Meeting Rooms (E350–E354) Arie Crown Balcony Level 2 Exhibition Halls Meeting Rooms (E250–E272) Arie Crown Theater Arie Crown Theater Roche bus transfer gate: 38 Level 1 Offices Lakeside Center Level 4 Meeting Rooms (N426–N427) Level 3 Exhibition Halls Level 2 Meeting Rooms (N226–N231) Level 1 Exhibition Halls Meeting Rooms (N126–N140) North Building 8 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Level 5 Meeting Rooms (S501–S505) Level 4 Vista Room (S406) Meeting Rooms (S401–S405) Level 3 Exhibition Halls Grand Concourse Level 2 Food Court/Restaurant Shops & Services Metra Trains Level 1 Grand Ballroom (S100) Meeting Rooms (S101–S106) South Building Level 5 Rooftop Garden Level 4 Meeting Rooms Level 3 Ballroom Exhibition Hall Level 2 Food Court/ Restaurant Shops & Services Level 1 Central Transportation Center Meeting Rooms West Building 9 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner 10 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Key Key to symbols used throughout the planner A Avastin H Herceptin M MabThera T Tarceva X Xeloda 11 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Saturday 31 May GENERAL POSTER SESSION Time: 08:00-12:00 Venue: S Hall A1 Genitourinary cancer A A Efficacy and safety of first-line bevacizumab (BEV) plus interferon-␣2a (IFN) in patients (pts) ⭓65 years with metastatic renal cell carcinoma (mRCC) (E Bajetta; Poster 4D, Abstract 5095) Costs of managing side effects in the treatment of first line metastatic renal cell carcinoma (mRCC) in Germany, France, and UK: Bevacizumab (BEV) + interferon alpha-2a (IFN) compared with sunitinib (G Mickisch; Poster 6H, Abstract 5110) ORAL ABSTRACT PRESENTATION SESSION Time: 15:00-18:00 Venue: E Hall D1 Gastrointestinal (colorectal) cancer A Initial safety report of NSABP C-08, a randomized phase III study of modified 5-fluorouracil (5-FU)/leucovorin (LCV) and oxaliplatin (OX) (mFOLFOX6) with or without bevacizumab (bev) in the adjuvant treatment of patients with stage II/III colon cancer (CJ Allegra; Abstract 4006) Time: 15:15-15:30 A X Randomized phase III study of capecitabine, oxaliplatin, and bevacizumab with or without cetuximab in advanced colorectal cancer (ACC), the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG) (CJ Punt; Abstract LBA4011) Time: 16:45-17:00 12 A Avastin X Xeloda 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Saturday 31 May ORAL ABSTRACT PRESENTATION SESSION Time: 15:00-18:00 Venue: W375e Genitourinary cancer (testes, kidney and bladder) A Update on AVOREN trial in metastatic renal cell carcinoma (mRCC): Efficacy and safety in subgroups of patients (pts) and pharmacokinetic (PK) analysis (BJ Escudier; Abstract 5025) Time: 16:15-16:30 A Avastin 13 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Sunday 1 June ORAL ABSTRACT PRESENTATION SESSION Time: 08:00-11:00 Venue: E354b Lymphoma M Improved outcome of elderly patients with poor-prognosis diffuse large B-cell lymphoma (DLBCL) after dose-dense rituximab: results of the DENSE-R-CHOP-14 trial of the German High-Grade Non-Hodgkin Lymphoma Study Group (DSHNHL) (M Pfreundschuh; Abstract 8508) Time: 08:45-09:00 ORAL ABSTRACT PRESENTATION SESSION Time: 08:00-11:00 Venue: E Hall D1 Breast cancer - metastatic A Randomized, double-blind, placebo-controlled, phase III study of bevacizumab with docetaxel or docetaxel with placebo as first-line therapy for patients with locally recurrent or metastatic breast cancer (mBC): AVADO (D Miles; Abstract LBA1011) Time: 08:30-08:45 H Randomized study comparing efficacy/toxicity of monotherapy trastuzumab followed by monotherapy docetaxel at progression, and combination trastuzumab/ docetaxel as first-line chemotherapy in HER2-neu positive, metastatic breast cancer (MBC) (HERTAX study) (M Bontenbal; Abstract 1014) Time: 09:00-09:15 14 M MabThera A Avastin H Herceptin 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Sunday 1 June H A randomized study of lapatinib alone or in combination with trastuzumab in heavily pretreated HER2+ metastatic breast cancer progressing on trastuzumab therapy (J O’Shaughnessy; Abstract 1015) Time: 09:15-09:30 POSTER DISCUSSION SESSION Time: 08:00-12:00 [discussion 11:00-12:00] Venue: E450a [E Hall D2] Gastrointestinal (colorectal) cancer A A X A X X Final efficacy results for bevacizumab plus standard first-line chemotherapies in patients with metastatic colorectal cancer: First BEAT (SR Berry; Poster 12, Abstract 4025) International multi-centre randomised Phase II/III study of Capecitabine (Cap), bevacizumab (Bev) and mitomycin C (MMC) as first-line treatment for metastatic colorectal cancer (mCRC): Final safety analysis of the AGITG MAX trial (T Price; Poster 16, Abstract 4029) Activity of the combination of bevacizumab (Bev) with capecitabine/irinotecan (CapIri/Bev) or capecitabine/ oxaliplatin (CapOx/Bev) in advanced colorectal cancer (ACRC): A randomized phase II study of the AIO Colorectal Study Group (AIO trial 0604) (AC Reinacher-Schick; Poster 17, Abstract 4030) Randomized trial comparing cetuximab plus XELIRI versus cetuximab plus XELOX as first line treatment of patients with metastatic colorectal cancer (mCRC): A study of the German AIO CRC study group (V Heinemann; Poster 20, Abstract 4033) H Herceptin A Avastin X Xeloda 15 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Sunday 1 June GENERAL POSTER SESSION Time: 14:00-18:00 Venue: S Hall A1 Lung cancer - metastatic T A A T A T 16 MERIT: analysis of differential gene expression in patients (pts) with advanced non-small-cell lung cancer (NSCLC) treated with erlotinib (P Delmar; Poster 42A, Abstract 8046) Safety of first-line bevacizumab-based therapy with concomitant cardiovascular or anticoagulation medication in advanced or recurrent non-squamous non-small cell lung cancer (NSCLC) in MO19390 (SAiL) (F Griesinger; Poster 42D, Abstract 8049) Effects of diagnostic method and surgery on safety of firstline bevacizumab plus chemotherapy in advanced or recurrent non-squamous non-small cell lung cancer (NSCLC): MO19390 (SAiL) (C-M Tsai; Poster 43E, Abstract 8058) Efficacy of erlotinib in patients (pts) with advanced nonsmall-cell lung cancer (NSCLC) relative to clinical characteristics: subset analyses from the TRUST study (SG Allan; Poster 46D, Abstract 8081) Safety of bevacizumab-based therapy as first-line treatment of patients with advanced or recurrent non-squamous nonsmall cell lung cancer (NSCLC): MO19390 (SAiL) (E Dansin; Poster 46H, Abstract 8085) A phase II study of first-line erlotinib in patients (pts) with stage IIIb/IV non-small-cell lung cancer (NSCLC) including dose escalation to toxicity in current and former smokers (C/FS) (B Besse; Poster 51H, Abstract 8111) T Tarceva A Avastin 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Monday 2 June GENERAL POSTER SESSION Time: 08:00-12:00 Venue: S Hall A1 Gastrointestinal (colorectal) cancer X A X A Capecitabine and oxaliplatin as first-line treatment in patients with metastatic colorectal cancer (MCRC): A pooled analysis of randomized phase II-III trials (R Porschen; Poster 3E, Abstract 4055) Waterfall plot analysis of XELOX or XELIRI with cetuximab or bevacizumab in patients with advanced colorectal cancer (ACRC): Combined analysis of two randomized first-line phase II trials of the AIO CRC study group (D Arnold; Poster 5E, Abstract 4067) The safety of long-term bevacizumab use: Results from the BRiTE observational cohort study (OCS) (D Purdie; Poster 14G, Abstract 4103) POSTER DISCUSSION SESSION Time: 08:00-12:00 [discussion 12:00-13:00] Venue: W375e lobby [W375d] Lung cancer - metastatic T T FAST-ACT: A phase II randomized double-blind trial of sequential erlotinib and chemotherapy as first-line treatment in patients (pts) with stage IIIB/IV non-small cell lung cancer (NSCLC) (JS Lee; Poster 12, Abstract 8031) Intermittent erlotinib (ERL) schedules in combination with pemetrexed (PEM): Phase I schedules designed to achieve pharmacodynamic separation (AM Davies; Poster 13, Abstract 8032) X Xeloda A Avastin T Tarceva 17 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Monday 2 June GENERAL POSTER SESSION Time: 14:00-18:00 Venue: S Hall A1 Breast cancer - local-regional and adjuvant therapy X First report of the European Cooperative Trial in Operable Breast Cancer II (ECTO II): Effects of primary chemoendocrine therapy on local-regional disease in ER-positive breast cancer (M Zambetti; Poster 11G, Abstract 588) GENERAL POSTER SESSION Time: 14:00-18:00 Venue: S Hall A1 Breast cancer - metastatic X H A X 18 Randomized trial of first-line docetaxel + capecitabine (XT) versus docetaxel + epirubicin (ET) for metastatic breast cancer (MBC): Efficacy results of ERASME-4/CAPEDOCEPIDOC (T Bachelot; Poster 24G, Abstract 1049) Observational Demetra study: Survival of metastatic breast carcinoma patients after treatment with trastuzumab (S Ménard; Poster 31G, Abstract 1062) A phase II trial investigating if bevacizumab in combination with hormone therapy will reverse acquired estrogen independence in metastatic breast cancer patients (C Falkson; Poster 34B, Abstract 1074) A novel capecitabine dosing schedule combined with bevacizumab is safe and active in patients with metastatic breast cancer: A phase II study (T Traina; Poster 40H, Abstract 1101) X Xeloda H Herceptin A Avastin 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Monday 2 June ORAL ABSTRACT PRESENTATION SESSION Time: 15:00-18:00 Venue: E Hall D2 Gastrointestinal (noncolorectal) cancer A T A randomized, double-blind, placebo (P) controlled, multicenter phase III trial to evaluate the efficacy and safety of adding bevacizumab (B) to erlotinib (E) and gemcitabine (G) in patients (pts) with metastatic pancreatic cancer (W Vervenne; Abstract 4507) Time: 15:45-16:00 A Avastin T Tarceva 19 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Tuesday 3 June POSTER DISCUSSION SESSION Time: 08:00-12:00 [discussion 11:00-12:00] Venue: E450b [E354a] Breast cancer - metastatic H X H H X A 20 Capecitabine vs capecitabine vs + trastuzumab in patients with HER2-positive metastatic breast cancer progressing during trastuzumab treatment: the TBP phase III study (GBG 26/BIG 3-05) (G Von Minckwitz; Poster 6, Abstract 1025) Results of a phase II trial of trastuzumab (H) and pertuzumab (P) in patients (pts) with HER2-positive metastatic breast cancer (MBC) who had progressed during trastuzumab therapy (KA Gelmon; Poster 7, Abstract 1026) A phase I study of trastuzumab-DM1 (T-DM1), a first-inclass HER2 antibody-drug conjugate (ADC), in patients (pts) with advanced HER2+ breast cancer (BC) (M Beeram; Poster 9, Abstract 1028) Randomized, multicenter, phase III trial of docetaxel plus epirubicin (ET) with or without capecitabine (X) as firstline therapy for stage IV breast cancer (BC) (M Mansutti; Poster 15, Abstract 1034) Independent review of E2100 progression-free survival (PFS) with the addition of bevacizumab (B) to paclitaxel (P) as initial chemotherapy for metastatic breast cancer (MBC) (BJ Klencke; Poster 17, Abstract 1036) H Herceptin X Xeloda A Avastin 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Tuesday 3 June POSTER DISCUSSION SESSION Time: 08:00-12:00 [discussion 11:00-12:00] Venue: S403 [S406 Vista Room] Gastrointestinal (noncolorectal) cancer H HER2-positivity rates in advanced gastric cancer (GC): results from a large international phase III trial (Y-J Bang; Poster 14, Abstract 4526) H Herceptin 21 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Hotels Avenue Hotel Chicago 160 East Huron Street, Chicago, IL 60611 Tel: 312 787 2900 www.avenuehotelchicago.com Breakfast: Madison / Avenue room, 13th floor, 06:30-10:30 Blackstone Chicago 636 South Michigan Avenue, Chicago, IL 60605 Tel: 312 447 0955 www.marriott.com Breakfast: Room Chicago, 06:30-09:00 Chicago City Centre Hotel 300 East Ohio Street, Chicago, IL 60611 Tel: 312 787 6100 www.chicagocitycentrehotel.com Breakfast: Restaurant 300 East, 06:30-10:30 Congress Plaza Hotel 520 South Michigan Avenue, Chicago, IL 60605 Tel: 312 427 3800 www.congressplazahotel.com Breakfast: Great Hall, 2nd floor, 06:30-10:00 22 Hilton Chicago 720 South Michigan Avenue, Chicago, IL 60605 Tel: 312 922 4400 www.hilton.com Breakfast: The Pavilion, Mon-Fri 05:30-11:00; Sat 05:30-12:00; Sun 05:30-14:00 Hyatt Regency McCormick Place 2233 South Martin Luther King Drive, Chicago, IL 60616 Tel: 312 567 1234 www.mccormickplace.hyatt.com Breakfast: Shor, Grand Concourse, 06:30-11:00 Whitehall Hotel 105 East Delaware Place, Chicago, IL 60611 Tel: 312 944 6300 www.thewhitehallhotel.com Breakfast: Salon I–III, 2nd floor, 06:30-10:30 Wyndham Chicago 633 North St Clair Street, Chicago, IL 60611 Tel: 312 573 0300 www.wyndham.com Breakfast: Caliterra, 2nd floor, 06:30-11:00 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Map N State st Chicago Downtown W Division St Whitehall W Chicago Ave Avenue Wyndham W Ontario Chicago City Center W Ohio Navy Pier Hyatt Regency E Wacker D r W Wacker Dr W Randolph St Columbus Dr Palmer House W Jackson Blvd Lake Michigan Congress Parkway Congress Plaza Blackstone E Balbo Dr Hilton W Roosevelt Rd rive hore D Lake S S Michigan Ave S State st Hyatt Regency McCormick S Martin W Cermak Rd McCormick Place Dr ng Ki er Luth 23 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Notes 24 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Notes 25 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner Notes 26 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner 16/5/08 HLR44722_ASCO_PocketPlanner:HLR42220_ASCO_PocketPlanner F. Hoffmann-La Roche Ltd CH-4070 Basel Switzerland 16/5/08