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Journal of Familial Tumors Vol. 11 No. 1 January 2011 CONTENTS Special Articles : The Significance of Knowledge on Familial Cancers Preface for Special Articles ………………………………………… Shinichi Suzuki, Daisuke Aoki … 1 Familial Endometrial Cancer ……………………………………………………Yoshihito Ichikawa … 2 Clinical Characteristics of Hereditary and Familial Prostate Cancer in Japan …………………………Nobuaki Ohtake, Seiji Nakata, Kazuhiro Suzuki, Hidetoshi Yamanaka, Keiji Suzuki, Yoshitatsu Fukabori …5 Familial Occurrence of Pediatric Solid Malignancies Especially in Neuroblastoma and Wilms Tumor …………………………………………………………………………………Masayuki Kubota … 11 Nevoid Basal Cell Carcinoma Syndrome: Characteristics of Clinical Manifestations and Gene Mutations in Japanese Individuals ………………………………Toshiyuki Miyashita , Maiko Kiryu, Kayoko Saito , Katsuo Sugita, Mamiko Endo, Katsunori Fujii … 14 The Significance of Knowledge on Familial Cancers for Physician ……………………………………Hideki Shimodaira, Ken Saijo, Hiroshi Soeda, Keigo Komine, Masanobu Takahashi, Chikashi Ishioka … 19 Case Report A case of Multiple Gastric Cancers in a Remnant Stomach Developed in a Lynch Syndrome Patient …………Kohji Tanakaya, YuKo Hujiwara, Toshiaki Morihiro, Kiyoto Takehara, Takashi Arata, Masayuki Seita, Hitoshi Nakagawa, Hideki Aoki, Hitoshi Takeuchi, Rie Yamasaki … 23 Lecture ® TM Gene Expression Signature : MammaPrint and OncotypeDX ………………Nahomi Tokudome … 27 Abstracts The 13th Annual Meeting of Tohoku Familial Tumor Association, Abstracts ………………………… 32 Newsletter………………………………………………………………………………………………………… n1 The Japanese Society for Familial Tumors