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Patient State Analyzer 4000 Morgann Robitaille Biomedical Engineering University of Rhode Island, Kingston, RI 02881 Did you know that over 290,000 times a year, patients wake up during a surgical procedure and are aware of their surrounding and even worse, sometimes the pain? Over the past years, anesthesiology has not only grown as a science but also an art. It takes into account physical history and condition, duration of surgery and from there, the anesthesiologist chooses the appropriate drug to control the hypnotic and paralytic requirements. Before, without the use of equipment, anesthesiologists had to use their knowledge of each drug to decide how the patient is reacting and the effects he or she will have. This often meant that a patient could receive too much anesthesia, which would prolong the recovery from the drug or too little, making the patient awake and aware of their surroundings. To reduce the risk factor of patients coming back into consciousness, Physiometrix has developed a system that can monitor the effects of the anesthesia on the patient. The Patient State Analyzer (PSA) 4000, is intended to monitor the state of the brain by acquisition of real-time data and processed EEG signals (Patient State Index). Obtaining real-time data, heart rate and blood pressure gives an exact real-time picture of the patient's consciousness. The Patient State Index (PSI) is measured using algorithms that are plotted using numerical values and as a color-coded historical display. • PSI values between 25-50 shows a green trend which represents the patient is in sufficient hypnotic state and has a low probability of surgical recall. • Below 25 is shown in yellow, representing a very deep sleep that may result in long recovery from anesthesia. • Above 50, also in yellow, represents a lightening hypnosis. There are many advantages to using the PSA 4000 during surgical procedures. The system produces a continuos output throughout the duration of the procedure, which allows the anesthesiologist to be aware of the patients state at all times. Being aware of the state of hypnosis gives the anesthesiologist to make changes in the drug being administered. For example, the anesthesiologist can titrate drug levels while in surgery to make sure of rapid patient wakeups while minimizing postoperative complications in the PACU. They can also know when the patient might becoming aware and therefore administer more of the drug. Also because the PSA 4000 was designed to be impervious to interference, the anesthesiologist is aware at all times of the patient's condition even during other patient manipulations.