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Eisai Corporate Factsheet History 1941: Eisai founded in Japan 1961: Listed on the Toyko stock exchange 1970: Eisai establishes its first Asian operation in Indonesia 1981: Eisai establishes its North American operation in California 1988: European operations established 1990: Eisai establishes a UK R&D operation, Eisai London Research Laboratories at University College London. 1993: Eisai introduces the corporate philosophy of hhc (the Human Health Care) 1997: Aricept® (donepezil hydrochloride) the leading treatment for Alzheimer’s disease first launched (USA) 1997: Pariet® (rabeprazole sodium) a proton pump inhibitor (PPI) used in the treatment of gastro-intestinal disorders first launched (Japan) 2001: First Environmental and Social Report published 2004: European Regional HQ established (London) 2005: Eisai started marketing Zonegran® (zonisamide) in the U.S. 2006: Plans announced for a strategic European base in UK Company Information Eisai employs more than 8,000 people worldwide and operates in over 30 countries including the UK, Germany, France, Spain, Italy, Switzerland, Sweden, Austria, Ireland, USA, Taiwan, China, Korea, India, plus its home market of Japan. Eisai is ranked amongst the world’s top 20 pharmaceutical companies with group sales of £2.6 billion. More than 50% of group sales are derived from outside Japan. Focuses its research efforts in three therapeutic areas: neurology, gastro-intestinal disorders and oncology/critical care. Eisai is the company behind the well known drug brands Aricept® (donepezil hydrochloride) used in the treatment of Alzheimer’s disease, Pariet® (rabeprazole) a proton pump inhibitor (PPI) used in the treatment of gastro-intestinal disorders and Zonegran® (zonisamide) for the treatment of epilepsy. Eisai plans to bring a number of new products to market in the coming years including potential new treatment for Alzheimer’s Disease, Parkinson’s, epilepsy, multiple sclerosis, and migraine prophylaxis. The company also has several novel cancer treatments in clinical development. For further information visit www.eisai.co.jp