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Supplemental digital content
Supplemental digital content to: Discrepancy between Financial Disclosures of Authors of
Clinical Practice Guidelines and Reports by Industry
Nikolaos Andreatos, MD, Ioannis M. Zacharioudakis, MD, Fainareti N. Zervou, MD,
Maged Muhammed, MD, and Eleftherios Mylonakis, MD, PhD
Guideline
Author Authors Authors
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with
data
significant
funding
Authors
with
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funding
and
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COI
Autho
with
signifi
fundin
and
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COI
1)Guideline for autologous tissue management
6
0
0
0
0
2) Screening for chlamydia and gonorrhea: U.S.
Preventive Services Task Force recommendation
statement
16
1
1
1
0
3) Behavioral counseling interventions to prevent
sexually transmitted infections: U.S. Preventive Services
Task Force recommendation statement
16
1
1
1
0
4)An official American Thoracic Society clinical
practice guideline: the diagnosis of intensive care unitacquired weakness in adults
18
2
2
2
0
5)Low-dose aspirin use for the prevention of morbidity
and mortality from preeclampsia: U.S. Preventive
Services Task Force recommendation statement
17
2
2
2
0
6)An international ISHLT/ATS/ERS clinical practice
guideline: diagnosis and management of bronchiolitis
obliterans syndrome
45
17
8
8
0
7)VA/DoD clinical practice guideline for the
management of chronic kidney disease in primary care
34
3
0
0
0
8)VA/DoD clinical practice guideline for the
management of chronic obstructive pulmonary disease
33
2
2
2
0
9) Guidelines of care for the management of atopic
dermatitis. Section 4. Prevention of disease flares and
use of adjunctive therapies and approaches
23
14
8
7
1
10) Screening for asymptomatic carotid artery stenosis:
U.S. Preventive Services Task Force recommendation
16
1
1
1
0
Footnote: COI: Conflict of Interest
statement
11) Screening for abdominal aortic aneurysm: U.S.
Preventive Services Task Force recommendation
statement
16
1
1
1
0
12)Screening for hepatitis B virus infection in
nonpregnant adolescents and adults: U.S. Preventive
Services Task Force recommendation statement
16
1
1
1
0
13)Screening for cognitive impairment in older adults:
U.S. Preventive Services Task Force recommendation
statement.
14
1
1
1
0
14)Prevention of dental caries in children from birth
through age 5 years: U.S. Preventive Services Task
Force recommendation statement.
14
2
1
1
0
15)Screening for suicide risk in adolescents, adults, and
older adults in primary care: U.S. Preventive Services
Task Force recommendation statement.
17
1
0
0
0
16)Primary care behavioral interventions to reduce
illicit drug and nonmedical pharmaceutical use in
children and adolescents: U.S. Preventive Services Task
Force recommendation statement
13
2
0
0
0
17)Vitamin, mineral, and multivitamin supplements for
the primary prevention of cardiovascular disease and
cancer: U.S. Preventive Services Task Force
recommendation statement
12
2
0
0
0
18)Screening for gestational diabetes mellitus: U.S.
Preventive Services Task Force recommendation
statement
17
3
0
0
0
19)Screening for lung cancer: U.S. Preventive Services
Task Force recommendation statement
16
3
0
0
0
20) Screening for oral cancer: U.S. Preventive Services
Task Force recommendation statement
16
3
0
0
0
21)Risk assessment, genetic counseling, and genetic
testing for BRCA-related cancer in women: U.S.
Preventive Services Task Force recommendation
statement
16
3
0
0
0
Footnote: COI: Conflict of Interest
5
4
0
0
0
23)Pediatric hydrocephalus: systematic literature review 7
and evidence-based guidelines. Part 2: management of
posthemorrhagic hydrocephalus in premature infants
4
0
0
0
24)Pediatric hydrocephalus: systematic literature review 6
and evidence-based guidelines. Part 6: preoperative
antibiotics for shunt surgery in children with
hydrocephalus: a systematic review and meta-analysis
3
0
0
0
25)Pediatric hydrocephalus: systematic literature review 6
and evidence-based guidelines. Part 10: change in
ventricle size as a measurement of effective treatment of
hydrocephalus
3
0
0
0
26)Pediatric hydrocephalus: systematic literature review 4
and evidence-based guidelines. Part 8: management of
cerebrospinal fluid shunt infection
2
0
0
0
27)Pediatric hydrocephalus: systematic literature review 4
and evidence-based guidelines. Part 7: antibioticimpregnated shunt systems versus conventional shunts in
children: a systematic review and meta-analysis
2
0
0
0
28)Pediatric hydrocephalus: systematic literature review 5
and evidence-based guidelines. Part 4: cerebrospinal
fluid shunt or endoscopic third ventriculostomy for the
treatment of hydrocephalus in children
4
0
0
0
29)Pediatric hydrocephalus: systematic literature review 4
and evidence-based guidelines. Part 3: endoscopic
computer-assisted electromagnetic navigation and
ultrasonography as technical adjuvants for shunt
placement
1
0
0
0
30)Pediatric hydrocephalus: systematic literature review 4
and evidence-based guidelines. Part 9: effect of
ventricular catheter entry point and position
1
0
0
0
6
6
3
3
0
22) Pediatric hydrocephalus: systematic literature
review and evidence-based guidelines. Part 5: effect of
valve type on cerebrospinal fluid shunt efficacy
31) The role of targeted therapies in the management of
progressive glioblastoma: a systematic review and
evidence-based clinical practice guideline
Footnote: COI: Conflict of Interest
32)Deep brain stimulation for obsessive-compulsive
disorder: systematic review and evidence-based
guideline sponsored by the American Society for
Stereotactic and Functional Neurosurgery and the
Congress of Neurological Surgeons (CNS) and endorsed
by the CNS and American Association of Neurological
Surgeons
10
7
4
1
3
33) Care of the adult patient with a brain tumor
8
0
0
0
0
34)Care of the pediatric patient with a brain tumor
7
0
0
0
0
35)Guideline for preoperative patient skin antisepsis
7
0
0
0
0
36)Guideline for care of the patient receiving local
anesthesia
6
0
0
0
0
37)Guideline for surgical attire
9
0
0
0
0
38)Guideline for management of wounds in patients with 7
lower-extremity arterial disease
0
0
0
0
8
39)Energy expenditure: measuring resting metabolic
rate (RMR) in the healthy and non-critically ill evidencebased nutrition practice guideline
0
0
0
0
40)Prevention of type 2 diabetes evidence-based
nutrition practice guideline
8
0
0
0
0
41)Adult weight management evidence-based nutrition
practice guideline
5
0
0
0
0
42)Guidelines for the practice and performance of
manipulation under anesthesia
3
0
0
0
0
43)Evidence-based clinical practice guideline: eye care
of the patient with diabetes mellitus
20
7
2
2
0
44)ACR Appropriateness Criteria® recurrent lower
urinary tract infections in women
17
7
4
4
0
45) ACR Appropriateness Criteria® multiple brain
metastases
17
8
3
3
0
Footnote: COI: Conflict of Interest
46)ACR Appropriateness Criteria® radiologic
management of lower gastrointestinal tract bleeding
13
12
5
5
0
47)ACR Appropriateness Criteria® rib fractures
18
9
1
1
0
48) ACR Appropriateness Criteria® follow-up of
Hodgkin lymphoma
17
11
5
5
0
49)ACR Appropriateness Criteria® indeterminate renal
mass
15
8
4
4
0
50)ACR Appropriateness Criteria® acute onset of
scrotal pain — without trauma, without antecedent mass
16
4
2
2
0
51) ACR Appropriateness Criteria® postradical
prostatectomy irradiation in prostate cancer
14
11
5
5
0
52)ACR Appropriateness Criteria® post-treatment
surveillance of bladder cancer
14
4
2
2
0
53) ACR Appropriateness Criteria® infertility
16
7
1
1
0
54) ACR Appropriateness Criteria® hematuria
18
8
3
3
0
55)ACR Appropriateness Criteria® lower urinary tract
symptoms: suspicion of benign prostatic hyperplasia
14
5
2
2
0
56)ACR Appropriateness Criteria® seizures and
epilepsy
16
7
4
4
0
57) ACR Appropriateness Criteria® dementia and
movement disorders
16
6
3
3
0
58) ACR Appropriateness Criteria® follow-up and
retreatment of brain metastases
17
7
1
1
0
59) ACR Appropriateness Criteria® pre-irradiation
evaluation and management of brain metastases
16
6
2
2
0
60) ACR Appropriateness Criteria® non-spine bone
metastases
14
9
2
2
0
61) ACR Appropriateness Criteria® metastatic epidural
spinal cord compression and recurrent spinal metastasis
15
11
2
2
0
Footnote: COI: Conflict of Interest
17
9
2
2
0
63) ACR Appropriateness Criteria® ductal carcinoma in 15
situ
8
2
2
0
64) ACR Appropriateness Criteria® breast pain
12
7
2
2
0
65) ACR Appropriateness Criteria® stage I breast
cancer: initial workup and surveillance for local
recurrence and distant metastases in asymptomatic
women
17
11
4
4
0
66) ACR Appropriateness Criteria® recurrent rectal
cancer
17
11
2
2
0
67) ACR Appropriateness Criteria® rectal cancermetastatic disease at presentation
17
9
2
2
0
68) ACR Appropriateness Criteria® local excision in
rectal cancer
17
9
2
2
0
69) ACR Appropriateness Criteria® assessment of
gravid cervix
12
7
1
1
0
70) ACR Appropriateness Criteria® abnormal vaginal
bleeding
17
7
1
1
0
71) ACR Appropriateness Criteria® advanced stage
endometrial cancer
17
10
1
1
0
72) ACR Appropriateness Criteria® pelvic floor
dysfunction
14
5
1
1
0
73) ACR Appropriateness Criteria® role of adjuvant
therapy in the management of early stage cervical
cancer
17
10
1
1
0
74) ACR Appropriateness Criteria® occupational lung
diseases
13
7
1
1
0
75) ACR Appropriateness Criteria® acute respiratory
illness in immunocompromised patients
13
7
1
1
0
76) ACR Appropriateness Criteria® nonsurgical
treatment for locally advanced non-small-cell lung
cancer: good performance status/definitive intent
13
9
4
4
0
62) ACR Appropriateness Criteria® evaluation of the
symptomatic male breast
Footnote: COI: Conflict of Interest
77) ACR Appropriateness Criteria® hemoptysis
17
9
1
1
0
78) ACR Appropriateness Criteria® suspected infective
endocarditis
13
10
3
3
0
79) ACR Appropriateness Criteria® acute chest pain —
suspected aortic dissection
14
9
3
3
0
80) ACR Appropriateness Criteria® chest pain
suggestive of acute coronary syndrome
13
7
2
2
0
81) ACR Appropriateness Criteria® blunt chest trauma
— suspected aortic injury
11
7
5
5
0
82) ACR Appropriateness Criteria® imaging in the
diagnosis of thoracic outlet syndrome
19
14
7
7
0
83) ACR Appropriateness Criteria® retreatment of
recurrent head and neck cancer after prior definitive
radiation
14
8
2
2
0
84) ACR Appropriateness Criteria® aggressive
nonmelanomatous skin cancer of the head and neck
15
9
3
3
0
85) ACR Appropriateness Criteria® palpable abdominal 14
mass
7
3
3
0
86) ACR Appropriateness Criteria® left lower quadrant
pain — suspected diverticulitis
14
7
4
4
0
87) ACR Appropriateness Criteria® resectable stomach
cancer
18
9
2
2
0
88) ACR Appropriateness Criteria® vomiting in infants
up to 3 months of age
17
5
1
1
0
89) ACR Appropriateness Criteria® head trauma —
child
20
8
1
1
0
90) ACR Appropriateness Criteria® acute trauma to the
ankle
16
6
0
0
0
91) ACR Appropriateness Criteria® acute trauma to the
foot
17
6
0
0
0
92) ACR Appropriateness Criteria® acute trauma to the
knee
16
7
1
1
0
Footnote: COI: Conflict of Interest
93) ACR Appropriateness Criteria® radiologic
management of infected fluid collections
12
8
5
5
0
94) ACR Appropriateness Criteria® liver lesion —
initial characterization
13
7
6
6
0
95) ACR Appropriateness Criteria® diffuse large B-cell
lymphoma
17
11
5
5
0
96) ACR Appropriateness Criteria® intensive care unit
patients
18
9
1
1
0
97) ACR Appropriateness Criteria® Crohn disease
13
8
4
4
0
98) ACR Appropriateness Criteria® upper extremity
swelling
13
9
6
6
0
99) Practice parameter for the assessment and treatment
of children and adolescents with autism spectrum
disorder
23
4
3
3
0
100) Guidelines of care for the management of atopic
dermatitis. Section 3. Management and treatment with
phototherapy and systemic agents
23
14
8
7
1
101) Guidelines of care for the management of atopic
dermatitis. Section 2. Management and treatment of
atopic dermatitis with topical therapies
23
14
8
7
1
102)Guidelines of care for the management of atopic
dermatitis. Section 1. Diagnosis and assessment of
atopic dermatitis
23
13
6
3
3
103) Clinical practice guideline: planning for labor and
vaginal birth after cesarean
11
3
0
0
0
104) Evidence-based guideline: assessment and
management of psychiatric disorders in individuals with
MS. Report of the Guideline Development Subcommittee
of the American Academy of Neurology
33
14
6
6
0
105) Summary of evidence-based guideline update:
prevention of stroke in nonvalvular atrial fibrillation.
Report of the Guideline Development Subcommittee of
the American Academy of Neurology
28
15
8
6
2
Footnote: COI: Conflict of Interest
32
19
11
8
3
107) Evidence-based guideline summary: diagnosis and 35
treatment of limb-girdle and distal dystrophies: report of
the Guideline Development Subcommittee of the
American Academy of Neurology and the Practice Issues
Review Panel of the American Association of
Neuromuscular and Electrodiagnostic Medicine
17
11
9
2
108) American Academy of Orthopaedic Surgeons
clinical practice guideline on management of anterior
cruciate ligament injuries
19
12
3
3
0
109) American Academy of Orthopaedic Surgeons
clinical practice guideline on detection and
nonoperative management of pediatric developmental
dysplasia of the hip in infants up to six months of age
25
7
1
1
0
110) American Academy of Orthopaedic Surgeons
appropriate use criteria for the management of pediatric
supracondylar humerus fractures
61
35
7
7
0
111) American Academy of Orthopaedic Surgeons
clinical practice guideline on management of hip
fractures in the elderly
24
15
3
3
0
112) Clinical practice guideline: acute otitis externa
9
4
1
1
0
113) Clinical practice guideline: tinnitus
23
7
1
1
0
114) Clinical practice guideline: the diagnosis,
management, and prevention of bronchiolitis
18
3
0
0
0
115) 2013 AHA/ACC/TOS guideline for the management
of overweight and obesity in adults: a report of the
American College of Cardiology/American Heart
Association Task Force on Practice Guidelines and The
Obesity Society
41
16
13
13
0
116) 2013 ACC/AHA guideline on the assessment of
cardiovascular risk: a report of the American College of
Cardiology/American Heart Association Task Force on
35
13
9
9
0
106) Summary of evidence-based guideline:
complementary and alternative medicine in multiple
sclerosis. Report of the Guideline Development
Subcommittee of the American Academy of Neurology
Footnote: COI: Conflict of Interest
Practice Guidelines
36
12
10
10
0
118) 2013 ACC/AHA guideline on the treatment of blood 35
cholesterol to reduce atherosclerotic cardiovascular risk
in adults: a report of the American College of
Cardiology/American Heart Association Task Force on
Practice Guidelines
16
12
12
0
119) 2014 AHA/ACC guideline for the management of
patients with valvular heart disease: a report of the
American College of Cardiology/American Heart
Association Task Force on Practice Guidelines
28
21
13
13
0
120) Pharmacologic therapy for pulmonary arterial
hypertension in adults: CHEST guideline and expert
panel report
14
12
9
5
4
121) Clinical policy: procedural sedation and analgesia
in the emergency department
25
12
2
1
1
122) Clinical policy: critical issues in the evaluation and 25
management of adult patients presenting to the
emergency department with seizures
8
2
1
1
123) American College of Medical Genetics and
Genomics guideline for the clinical evaluation and
etiologic diagnosis of hearing loss
11
4
0
0
0
124) Nonsurgical management of urinary incontinence
in women: a clinical practice guideline from the
American College of Physicians
17
2
1
1
0
125) Dietary and pharmacologic management to prevent 15
recurrent nephrolithiasis in adults: a clinical practice
guideline from the American College of Physicians
1
0
0
0
15
1
0
0
0
117) 2013 AHA/ACC guideline on lifestyle management
to reduce cardiovascular risk: a report of the American
College of Cardiology/American Heart Association Task
Force on Practice Guidelines
126) Screening pelvic examination in adult women: a
clinical practice guideline from the American College of
Physicians
Footnote: COI: Conflict of Interest
127) Diagnosis of obstructive sleep apnea in adults: a
clinical practice guideline from the American College of
Physicians
18
4
1
1
0
128) American Gastroenterological Association Institute
guideline on pharmacological management of irritable
bowel syndrome
14
6
5
5
0
129) Occupational therapy practice guidelines for home
modifications
5
0
0
0
0
130) Occupational therapy practice guidelines for adults 3
with neurodegenerative diseases
0
0
0
0
17
7
2
2
0
17
132) Methadone safety: a clinical practice guideline
from the American Pain Society and College on
Problems of Drug Dependence, in collaboration with the
Heart Rhythm Society
9
1
1
0
131) Guidelines for the prevention of stroke in women: a
statement for healthcare professionals from the
American Heart Association/American Stroke
Association
133) Atypical subtrochanteric and diaphyseal femoral
fractures: second report of a Task Force of the
American Society for Bone and Mineral Research
26
10
3
3
0
134) A.S.P.E.N. clinical guidelines: support of pediatric
patients with intestinal failure at risk of parenteral
nutrition–associated liver disease
6
2
1
1
0
135) A.S.P.E.N. clinical guidelines: parenteral nutrition
ordering, order review, compounding, labeling, and
dispensing
10
0
0
0
0
136) The role of endoscopy in the evaluation and
management of dysphagia
20
9
4
4
0
137) Guidelines for safety in the gastrointestinal
endoscopy unit
7
3
2
2
0
138) The role of postoperative radiation therapy for
endometrial cancer: an ASTRO evidence-based
guideline
17
11
3
3
0
Footnote: COI: Conflict of Interest
139) Society of Surgical Oncology–American Society for
Radiation Oncology consensus guideline on margins for
breast-conserving surgery with whole-breast irradiation
in stages I and II invasive breast cancer
13
3
0
0
0
140) Management of venous leg ulcers: clinical practice
guidelines of the Society for Vascular Surgery and the
American Venous Forum
22
14
4
4
0
141) Practice guidelines for the perioperative
management of patients with obstructive sleep apnea: an
updated report by the American Society of
Anesthesiologists Task Force on Perioperative
Management of Patients with Obstructive Sleep Apnea
9
0
0
0
0
142) Practice parameters for the surgical treatment of
ulcerative colitis
18
10
5
5
0
143) Practice parameters for the treatment of sigmoid
diverticulitis
27
15
6
6
0
144) Screening, assessment, and care of anxiety and
depressive symptoms in adults with cancer: an American
Society of Clinical Oncology guideline adaptation
9
3
1
1
0
145) Sentinel lymph node biopsy for patients with earlystage breast cancer: American Society of Clinical
Oncology clinical practice guideline update
13
8
4
4
0
146) Screening, assessment, and management of fatigue
in adult survivors of cancer: an American Society of
Clinical Oncology Clinical Practice guideline
adaptation
13
3
2
0
2
147) Prevention and management of chemotherapyinduced peripheral neuropathy in survivors of adult
cancers: American Society of Clinical Oncology clinical
practice guideline
16
6
5
3
2
148) Systemic therapy for patients with advanced human
epidermal growth factor receptor 2-positive breast
cancer: American Society of Clinical Oncology clinical
practice guideline
16
13
10
6
4
149) Recommendations on disease management for
patients with advanced human epidermal growth factor
receptor 2-positive breast cancer and brain metastases:
16
13
10
6
4
Footnote: COI: Conflict of Interest
American Society of Clinical Oncology clinical practice
guideline
150) (1) American Society of Clinical Oncology clinical
practice guideline: update on adjuvant endocrine
therapy for women with hormone receptor–positive
breast cancer. (2) Adjuvant endocrine therapy for
women with hormone receptor–positive breast cancer:
American Society of Clinical Oncology clinical practice
guideline focused update
11
8
3
1
2
151) Chemotherapy and targeted therapy for women
with human epidermal growth factor receptor 2–
negative (or unknown) advanced breast cancer:
American Society of Clinical Oncology clinical practice
guideline
14
8
8
6
2
152) Systemic therapy in men with metastatic castration- 16
resistant prostate cancer: American Society of Clinical
Oncology and Cancer Care Ontario clinical practice
guideline
7
4
4
0
153) International ERS/ATS guidelines on definition,
evaluation and treatment of severe asthma
23
3
3
3
0
154) An official American Thoracic Society clinical
practice guideline: diagnosis, risk stratification, and
management of pulmonary hypertension of sickle cell
disease
20
12
8
7
1
155) Official American Thoracic Society technical
standards: spirometry in the occupational setting
8
2
0
0
0
156) Medical management of kidney stones: AUA
guideline
10
8
3
3
0
157) Urotrauma: AUA guideline
13
10
3
2
1
158) Evaluation and treatment of cryptorchidism: AUA
guideline
11
3
2
0
2
159) Diagnosis and treatment of interstitial
cystitis/bladder pain syndrome
15
8
3
3
0
160) Diagnosis and treatment of overactive bladder
(non-neurogenic) in adults: AUA/SUFU guideline
11
6
1
0
1
Footnote: COI: Conflict of Interest
161) Laboratory testing for the diagnosis of HIV
infection: updated recommendations
13
1
0
0
0
162) Preexposure prophylaxis for the prevention of HIV
Infection in the United States - 2014
13
2
0
0
0
163) Providing quality family planning services:
recommendations of CDC and the U.S. Office of
Population Affairs
34
3
0
0
0
164) Best evidence statement (BESt). Venous
thromboembolism (VTE) prophylaxis in children and
adolescents
8
2
0
0
0
165) Best evidence statement (BESt). Use of pressure
therapy for management of hypertrophic scarring
8
1
0
0
0
166) Evidence-based care guideline for conservative
management of lateral patellar dislocations and
instability in children and young adults aged 8-25 years
21
0
0
0
0
167) Best evidence statement (BESt). Physical therapy
during the hemopoietic stem cell transplant process to
improve quality of life
7
1
0
0
0
168) Best evidence statement (BESt). The use of yoga to
improve strength, balance, and coordinatio
3
0
0
0
0
169) Clinical Pharmacogenetics Implementation
Consortium guidelines for cytochrome P450 2D6
genotype and codeine therapy: 2014 update
13
3
1
1
0
170) Clinical Pharmacogenetics Implementation
Consortium guidelines for CYP2C9 and HLA-B
genotypes and phenytoin dosing
8
3
2
2
0
171) Clinical Pharmacogenetics Implementation
Consortium (CPIC) guidelines for IFNL3 (IL28B)
genotype and PEG interferon-α–based regimens
8
3
2
2
0
172) Clinical Pharmacogenetics Implementation
Consortium (CPIC) guidelines for ivacaftor therapy in
the context of CFTR genotype
8
1
1
1
0
173) Clinical Pharmacogenetics Implementation
Consortium (CPIC) guidelines for rasburicase therapy
in the context of G6PD deficiency genotype
8
0
0
0
0
Footnote: COI: Conflict of Interest
174) The Clinical Pharmacogenetics Implementation
Consortium guideline for SLCO1B1 and simvastatininduced myopathy: 2014 update.The Clinical
Pharmacogenetics Implementation Consortium
guideline for SLCO1B1 and simvastatin-induced
myopathy: 2014 update.
16
3
1
1
0
175) Principles of analytic validation of
immunohistochemical assays: guideline from the
College of American Pathologists Pathology and
Laboratory Quality Center
13
2
0
0
0
176) Team-based care to improve blood pressure
control: recommendation of the Community Preventive
Services Task Force
13
2
1
1
0
177) Infection prevention and control guideline for
cystic fibrosis: 2013 update
21
6
3
3
0
178) Cystic Fibrosis Foundation pulmonary guideline.
Pharmacologic approaches to prevention and
eradication of initial Pseudomonas aeruginosa infection
7
9
7
7
0
179) VA/DoD clinical practice guideline for the
diagnosis and management of hypertension in the
primary care setting
26
2
2
2
0
180) VA/DoD clinical practice guideline for the
management of chronic multisymptom illness
33
1
0
0
0
181) VA/DoD clinical practice guideline for screening
and management of overweight and obesity
34
2
0
0
0
182) VA/DoD clinical practice guideline for the nonsurgical management of hip and knee osteoarthritis
34
5
1
1
0
183) VA/DoD clinical practice guideline for the
management of upper extremity amputation
rehabilitation
40
0
0
0
0
184) Optimal timing of femur fracture stabilization in
polytrauma patients: a practice management guideline
from the Eastern Association for the Surgery of Trauma
12
7
2
1
1
185) Timing and type of surgical treatment of
Clostridium difficile-associated disease: a practice
management guideline from the Eastern Association for
12
10
2
2
0
Footnote: COI: Conflict of Interest
the Surgery of Trauma
186) Treatment of pressure ulcers. In: Prevention and
treatment of pressure ulcers: clinical practice guideline
48
1
0
0
0
187) Prevention of pressure ulcers. In: Prevention and
treatment of pressure ulcers: clinical practice guideline
31
1
0
0
0
188) Special populations. In: Prevention and treatment
of pressure ulcers: clinical practice guideline
40
2
0
0
0
189) Interventions for prevention and treatment of
pressure ulcers. In: Prevention and treatment of
pressure ulcers: clinical practice guideline
34
1
0
0
0
1
0
0
0
190) Evaluation and treatment of functional constipation 9
in infants and children: evidence-based
recommendations from ESPGHAN and NASPGHAN.
191) Consensus summary statement of the International
Multidisciplinary Consensus Conference on
Multimodality Monitoring in Neurocritical Care: a
statement for healthcare professionals from the
Neurocritical Care Society and the European Society of
Intensive Care Medicine
35
12
3
2
1
192) Nutrition management guideline for maple syrup
urine disease: an evidence- and consensus-based
approach.
9
0
0
0
0
193) 2013 IDSA clinical practice guideline for
vaccination of the immunocompromised host
11
5
2
0
2
194) Acute pain assessment and opioid prescribing
protocol. Health care protocol
20
1
0
0
0
195) Perioperative protocol. Health care protocol
14
2
0
0
0
196) Diagnosis and management of type 2 diabetes
mellitus in adults
10
0
0
0
0
197) Evidence assessments and guideline
recommendations in Lyme disease: the clinical
management of known tick bites, erythema migrans
rashes and persistent disease
13
7
1
1
0
Footnote: COI: Conflict of Interest
198) 2014 evidence-based guideline for the management
of high blood pressure in adults. Report from the panel
members appointed to the Eighth Joint National
Committee
17
4
2
1
1
199) Preventive male sexual and reproductive health
care: recommendations for clinical practice
13
3
1
1
0
200) Blood transfusion in the management of sickle cell
disease. In: Evidence-based management of sickle cell
disease
13
7
3
2
1
201) Managing acute complications of sickle cell
disease. In: Evidence-based management of sickle cell
disease
13
7
3
2
1
202) Managing chronic complications of sickle cell
disease. In: Evidence-based management of sickle cell
disease
13
7
3
2
1
203) Health maintenance for people with sickle cell
disease. In: Evidence-based management of sickle cell
disease
13
7
3
2
1
204) Hydroxyurea therapy in the management of sickle
cell disease. In: Evidence-based management of sickle
cell disease
13
7
3
2
1
205) Care of the HIV-exposed infant with indeterminate
status
10
2
0
0
0
206) Antiretroviral therapy
26
12
5
5
0
207) Guidance for the use of pre-exposure prophylaxis
(PrEP) to prevent HIV transmission
36
13
4
4
0
208) Diagnosis and treatment of degenerative lumbar
spondylolisthesis
19
15
6
6
0
209) Diagnosis and treatment of adult isthmic
spondylolisthesis
20
13
8
8
0
210) Guidelines for laparoscopic peritoneal dialysis
access surgery
8
6
3
3
0
211) Androgen therapy in women: a reappraisal: an
Endocrine Society clinical practice guideline
8
5
3
3
0
Footnote: COI: Conflict of Interest
212) Paget's disease of bone: an Endocrine Society
clinical practice guideline
7
3
1
0
1
213) Management of acute atrial fibrillation and atrial
flutter in non-pregnant hospitalized adults
10
3
1
1
0
214) Secondary prevention of ischemic heart disease
and stroke in adults
7
3
0
0
0
215) Screening and management of lipids
6
1
0
0
0
216) Essential hypertension
6
1
1
0
1
217) Venous thromboembolism (VTE)
10
3
2
1
1
218) Evaluation and management of gallstone-related
diseases in non-pregnant adults
10
3
0
0
0
219) Management of chronic kidney disease
7
1
1
1
0
220) Conservative care options for work-related
epicondylosis
8
0
0
0
0
221) Conservative care options for work-related
mechanical shoulder conditions
9
0
0
0
0
222) Options for documenting functional improvement in 9
conservative care
0
0
0
0
8
3
3
0
223) Work-related carpal tunnel syndrome diagnosis
and treatment guideline
20
Supplemental digital content
(Supplemental table 1)
Footnote: COI: Conflict of Interest
Supplemental digital content to: Discrepancy between Financial Disclosures of Authors of
Clinical Practice Guidelines and Reports by Industry
Nikolaos Andreatos, MD, Ioannis M. Zacharioudakis, MD, Fainareti N. Zervou, MD,
Maged Muhammed, MD, and Eleftherios Mylonakis, MD, PhD
Supplemental table 1. Frequency and percentages of authors with available Open Payments data per
specialty. Chi-squared test is used for comparison. A p value of < .05 was considered statistically
significant.
Total number of authors per
guideline category
Number of authors with available
Open Payment data (% of total
authors per specialty)
p valu
Hematology/oncology
613
315 (51.4%)
.39
General medicine
711
158 (22.2%)
< .001
Orthopedics/Trauma
361
153 (42.4%)
.02
Cardiology
200
91 (45.5%)
.09
Neurology
202
89 (44.1%)
.05
Surgery
240
88 (36.7%)
.001
Pulmonology
196
63 (32.1%)
< .001
Dermatology
100
56 (56.0%)
Ref.
Urology
135
50 (37.0%)
.004
Gastroenterology
101
46 (45.5%)
.14
Infectious disease
122
42 (34.4%)
.001
Radiology
75
39 (52.0%)
.60
Obstetrics/ Gynecology
153
38 (24.8%)
< .001
Pediatrics
108
23 (21.3%)
< .001
Critical care
71
23 (32.4%)
.002
Emergency medicine
50
20 (40.0%)
.06
Psychiatry
57
14 (24.6%)
< .001
Guidelines categorized by
specialty
Footnote: COI: Conflict of Interest
Endocrinology
25
8 (32.0%)
.03
Ophthalmology
20
7 (35.0%)
.09
Nephrology
41
4 (9.8%)
< .001
Pathology
13
2 (15.4%)
.006
3,594
1,329 (37.0%)
TOTAL
Footnote: COI: Conflict of Interest
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