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TASCF’s Approach to
New Venture Development
The AviGenics Case
Journée Tendances 2000
Montreal, Quebec
19 May 2000
1
TARAVAL ASSOCIATES LLC
Outline
• The Idea of a “Spin-In”
• Georgia Research Alliance
• AviGenics
– Background
– Value Creation
• Other Mechanisms for Commercialization
• Taraval Associates Seed Capital Fund
2
TARAVAL ASSOCIATES LLC
The University
of Georgia
AviGenics, inc.
3
TARAVAL ASSOCIATES LLC
The University
of Georgia
University of
Georgia
AviGenics, inc.
4
TARAVAL ASSOCIATES LLC
“Research centers and institutions are
undisputedly the most important factor in
incubating high-tech industries. “
“Formation of public-private ventures that aim
to establish and maintain leading-edge
regional research centers and educational
institutes is a critical long-term economic
growth strategy.”
The Milken Institute
5
TARAVAL ASSOCIATES LLC
There’s A Role For Government
Create an
environment that
propels research
and development
into economic
development
6
TARAVAL ASSOCIATES LLC
Mechanisms for Commercialization - 1
AviGenics
-
Angel & Venture Capital Backed Start-up
SR&L Agreements w/UGARF
Leases w/UGA
GRA & State have been very helpful
Licensed in considerable technology
Sponsoring Research at University of
Cincinnati & Overseas
The AviGenics case is unique because no
technology existed at UGA
prior to AviGenics' initiative.
7
TARAVAL ASSOCIATES LLC
Poultry Market
Poultry industry exceeds $30 billion
• Broilers (Meat)
• 8 billion birds/year U.S.
• 27 billion birds/year worldwide
• Layers (Eggs)
• 68 billion eggs/year U.S.
• 553 billion eggs/year worldwide
Current Needs/Problems
• Cost of vaccination and disease losses is ~ $750M/yr
• Limitations Of traditional breeding methods
8
TARAVAL ASSOCIATES LLC
Creating Value In AviGenics - 1
• Technology Development
– Risk Erosion - Hitting Milestones
– Risk Erosion - Multiple Approaches to Avian
Transgenesis
– Risk Erosion - Pilot Birds (D.O.T.)
– Knowledge Building & Know-how Making Birds
• Corporate Partnering
– Oakwood Laboratories -- Hen Oviduct Bioreactor (Inf)
– Metamorphic -- Agronomic Traits (↓
↓GDF-8)
• Technology Alliances & In-Licensing
• AviGenics - The Corporation
9
TARAVAL ASSOCIATES LLC
Creating Value In AviGenics - 2
In-Licensed Technology
& Technology Alliances
+
+
+
+
+
+
10
Nature Technology Corp.
Salk Institute
Univ. of Maryland
Stem Cell Sciences
Chromos Molec. Sys.
Univ. of Cincinnati
Avian Vector Patent
Ribozyme Knockouts
Accelerated Rooster Fertility
IRES Vectors
Artificial Chromosomes
Gut-Specific Promoters
TARAVAL ASSOCIATES LLC
Other Proven Mechanisms for
Commercialization
11
TARAVAL ASSOCIATES LLC
Mechanisms for Commercialization - 2
12
BioTransplant
-
HealthCare Investments --> NASDAQ
Harvard/MGH (TBRC)
Capitalized SCS
Funding(ed) Sponsored Research at Tufts,
Universities of Missouri, Wisconsin,
London, et al
A/F Protein
-
Privately Financed Venture
Bay City Capital just invested $5 million
Considerable support from Canadian govt.
Collaborations w/University of Toronto and
Memorial University (NFLD)
SCS (Australia)
- BTI capitalized SCS in Exchange for Exclusive
in Xenotransplantation
- Collaborations w/Universities of Edinburgh,
Melbourne and Monash
TARAVAL ASSOCIATES LLC
Mechanisms for Commercialization - 3
13
Smart Drug
Systems
- Raised $5 million from Bay City Capital
- Operations in Australia & Connecticut
- Licensed technology from Sumitomo
- Field trial agreement w/University of Melbourne
ProLinia
-
Founders Seeded This Venture
Negotiated SR&L Agreements w/UGARF
Negotiated Leases w/UGA
Negotiated Technology Licenses
w/BresaGen
- Negotiating Corporate Partnerships
w/Hog & Cattle Producers
TARAVAL ASSOCIATES LLC
Taraval Associates Seed Capital Fund
14
TARAVAL ASSOCIATES LLC
TASCF Mission
Overall
• Significant Capital Appreciation
• Private Equity Investments
• Very Early-Stage Companies
Primarily in the Life Sciences
• Willing to Travel to Regional Center of Excellence
Specific
• Shape Early-Stage Ventures Able to Attract Later-Stage
Funding and Corporate Partners
This is Success for TASCF
15
TARAVAL ASSOCIATES LLC
Old Approach With a New Twist
Seed Capital Is Essential But Not Sufficient
• Hands-On
• Gathering and protecting intellectual property
• Conveying a sense of urgency >> First Mover
Advantage
• Emphasis on creating value through revenue
generation and/or technical advancements
16
TARAVAL ASSOCIATES LLC
TASCF Portfolio Companies
AviGenics, inc.
Smart Drug Systems, Inc.
17
TARAVAL ASSOCIATES LLC