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Cold Medicines
by Karen Schroeder Kassel, MS, RD, MEd
En Español (Spanish Version)
Colds are caused by viruses; in fact, there are over 200 different viruses that cause colds. There are no medicines
to cure colds. Antibiotics are only effective against bacteria, not viruses. However, there are a variety or products
that may somewhat reduce cold symptoms. Many of these can be bought without a prescription. The main types
of over-the-counter (OTC) cold medicines are reviewed here:
Analgesics
Antitussives
Expectorants
Oral decongestants
These medicines may help reduce your symptoms. However, see your doctor if you have any of the following:
High fever (temperature above 102ºF [39ºC]) , skin rash, or continuing headache
Symptoms lasting more than 10 days or getting worse instead of better
Shortness of breath
Feeling faint
Confusion or feeling disoriented
Earache or drainage from your ear
Severe pain in your face or forehead
Swollen glands in the neck or jaw
People with moderate to severe pulmonary or cardiac disease, such as asthma, chronic
bronchitis, emphysema, angina, and hypertension, should consult with their doctor early in the course of their
symptoms and before taking any medicine. Children should also be seen earlier in the course of their illness,
especially if they are very young.
Analgesics
Analgesics relieve aches and pains and reduce fever.
Brand Names
Generic Name Brand Names
Aceta, Actamin, Aminofen, Apacet, Aspirin Free Anacin, Aspirin-Free Excedrin, Banesin,
Bayer Select, Dapa, Datril, Feverall, Genapap, Genebs, Liquiprin, Neopap, Oraphen-PD,
acetaminophen
Panadol, Phenaphen, Redutemp, Snaplets-FR, St. Joseph Aspirin-Free Fever Reducer, Suppap,
Tapanol, Tempra, Tylenol, Valorin
aspirin
Acuprin, Anacin, Ascriptin, Aspergum, Aspirin Regimen Bayer, Aspir-Low, Aspirtab, Bayer,
Bufferin, Buffex, Buffinol, Cope, Easprin, Ecotrin, Empirin, Gensan, Halfprin, Healthprin,
Magnaprin, Sloprin, St. Joseph Adult chewable Aspirin, ZORprin
ibuprofen
Advil, Dolgesic, Excedrin IB, Genpril, Haltran, Ibifon, Ibren, Ibu, Ibuprin, Ibuprohm,
Medipren, Midol IB, Motrin, Nuprin, Pamprin-IB, Q-Profen, Rufen, Trendar
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Copyright © 2011 EBSCO Publishing. All rights reserved.
ketoprofen
Actron, Orudis, Oruvail
naproxen
Aleve, Anaprox, Naprelan, Naprosyn
How These Medicines Work
Aspirin and non-steroidal anti-inflammatory drugs or NSAIDS (ibuprofen, ketoprofen, naproxen) inhibit the
formation of certain prostaglandins. These are substances in the body that are involved in various processes
including pain and body temperature. Acetaminophen probably works in a similar way, but it lacks the
anti-inflammatory effects of NSAIDS.
Proper Use
Take analgesics with food and a glass of water to decrease the chance of stomach upset. Delayed-release and
extended-release tablets have a special coating that makes them easier on the stomach.
Precautions While Using This Medicine
Accidental Overdosage—Many OTC medicines as well as prescription painkillers contain acetaminophen
(Tylenol). Although acetaminophen is quite safe when used as directed, when taken in excess it can cause liver
damage. Make sure to read the labels and do not “double up” on acetaminophen.
Children and Teens— Aspirin is not recommended for children and teens with a current or recent viral infection.
Check with your doctor before giving aspirin to a child or teen. Children can be given acetaminophen or
ibuprofen.
Pregnancy—Acetaminophen is usually considered the safest pain and fever reducer to use during pregnancy. Do
not take aspirin during pregnancy unless your doctor has ordered it.
Alcohol—If you will be taking more than an occasional one or two doses of acetaminophen, do not drink alcohol.
Doing so may increase the chance of liver damage, especially if you drink large amounts of alcoholic beverages
regularly, if you take more acetaminophen than is recommended on the package label, or if you take it regularly
for a long time.
Certain Conditions—If you have any of the following conditions, check with your doctor before taking an
analgesic:
Alcohol abuse
Kidney or liver disease
Peptic ulcer
Phenylketonuria (PKU)
Severe allergies
Bleeding disorders
Pregnancy
Possible Side Effects
Possible side effects of analgesics include:
Abdominal or stomach cramps, pain, or discomfort
Heartburn or indigestion
Nausea or vomiting
Diarrhea
Dizziness, drowsiness, or lightheadedness
Tinnitus (ringing in the ears)
Easy bruising
Rash
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Copyright © 2011 EBSCO Publishing. All rights reserved.
Antitussives
Antitussive medicines (also called cough suppressants) are used to control coughing. However, there is limited
evidence that they work.
Brand Names
The main nonprescription antitussive is dextromethorphan. Products made from this drug include:
Benylin
Cough-X
Creo-Terpin
Delsym
Diabe-TUSS DM
Hold DM
Pertussin
Robitussin
Sucrets Cough Suppressant
Trocal
Vicks Cough Relief
How This Medicine Works
Dextromethorphan is thought to relieve cough by acting directly on the cough center in the brain to depress the
cough reflex.
Proper Use
Antitussives should not be used for persistent or chronic cough that occurs with smoking, asthma, chronic
bronchitis, or emphysema, or for cough accompanied by excessive mucus or phlegm.
Follow the dosage instructions on the product label or given by your doctor closely. In some cases,
dextromethorphan can be habit forming.
Precautions While Using This Medicine
If you have any of the following conditions, check with your doctor before taking an antitussive:
Asthma
Diabetes
Liver disease
Chronic bronchitis
Emphysema
Slowed breathing
Phenylketonuria
Pregnant
Possible Side Effects
Nausea or other gastrointestinal upset
Slight drowsiness
Dizziness
Nervousness or restlessness
Expectorants
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Copyright © 2011 EBSCO Publishing. All rights reserved.
Expectorants are used to clear phlegm from the lungs. Phlegm is an abnormal production of mucus. However,
there is limited evidence that they work.
Brand Names
The main non-prescription expectorant is guaifenesin. Products made from this drug include:
Anti-Tuss
Breonesin
Diabetic Tussin EX
Fenesin
Gee-Gee
Genatuss
GG-CEN
Glycotuss
Glytuss
Guiatuss
Halotussin
Humibid
Hytuss
Naldecon Senior EX
Organidin NR
Pneumomist
Robitussin
Scot-tussin Expectorant
Sinumist-SR
Touro EX
Uni-tussin
How This Medicine Works
Guaifenesin is though to increase respiratory tract fluid, which in turn should reduce the thickness of phlegm in
the lungs and enable it to be cleared more easily.
Proper Use
Drink plenty of water while taking guaifenesin to help loosen phlegm in the lungs.
Precautions While Using This Medicine
If you are pregnant or breastfeeding, check with your doctor before taking an oral decongestant.
Possible Side Effects
Nausea and/or vomiting
Diarrhea
Dizziness
Headaches
Rash
Oral Decongestants
These drugs help to reduce congestion.
Brand Names
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Copyright © 2011 EBSCO Publishing. All rights reserved.
A common decongestant that is available over the counter is pseudoephedrine. Products that contain this
ingredient include:
Cenafed
Chlor-Trimeton Non-Drowsy Decongestant
Decofed
Dimetapp
Drixoral
Efidac/24
Genaphed
Myfedrine
PediaCare Infants' Oral Decongestant Drops
Pseudo 60's
Sudafed
Triaminic
How This Medicine Works
Oral decongestants treat cold symptoms (but not the cold itself) by narrowing the blood vessels in the nasal
passages.
Proper Use
Follow the dosage instructions on the product label or given by your doctor closely.
Precautions While Using This Medicine
If you have any of the following conditions, check with your doctor before taking an oral decongestant:
Diabetes
Enlarged prostate
Glaucoma
Heart disease or a blood vessel disease
High blood pressure
Overactive thyroid
Pregnancy
Possible Side Effects
Nervousness
Excitability
Restlessness
Racing heart
Tremulousness
Dizziness
Weakness
Trouble sleeping
To avoid sleeping difficulties, take the last dose of decongestant several hours before bedtime.
With every medicine, there are important precautions to consider. These include allergies, interactions with other
drugs and medical conditions, and safety during pregnancy, lactation, and other stages of life.
RESOURCES:
American Academy of Family Physicians
http://www.aafp.org/
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Copyright © 2011 EBSCO Publishing. All rights reserved.
National Institute of Allergy and Infectious Diseases
http://www3.niaid.nih.gov/
CANADIAN RESOURCES:
Canadian Family Physician
http://www.cfpc.ca/
Canadian Institute for Health Information (CIHI)
http://www.cihi.ca/
REFERECES:
Acetaminophen. U.S. National LIbrary of Medicine PubMed Health website. Available at:
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000521/. Updated July 8, 2011. Accessed December 6, 2011.
Colds and the flu. American Academy of Family Physicians. Family Doctor.org website. Available at:
http://familydocto.... Updated October 15, 2011. Accessed December 6, 2011.
Dextromethorphan. U.S. National LIbrary of Medicine PubMed Health website. Available at:
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000695/. Updated July 8, 2011. Accessed December 6, 2011.
Guaifenesin and codeine. EBSCO Health Library website. Available at:
http://www.ebscohost.com/healthLibrary/.Updated Novmeber 2, 2010. Accessed December 6, 2011.
Pseudoephedrine. U.S. National LIbrary of Medicine PubMed Health website. Available at:
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000731/. Updated July 8, 2011. Accessed December 6, 2011.
Last reviewed December 2011 by Brian Randall, MD
Last Updated: 12/6/2011
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Copyright © 2011 EBSCO Publishing. All rights reserved.