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Holistic Healing and its Interaction with Western Medicine – COSIPA – June 2016 Holistic Healing and its Interaction with Western Medicine Ted C. Hanf JD, MPH Kegel, Tobin & Truce APC Southern California [email protected] Population of California by Origin • 10 Million Immigrants • 27% Foreign Born • ½ the children in Calif. have 1 foreign born parent • 53% Latin American • 37% Asian Source: ppic.org Council of Self-Insured Public Agencies Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 (c) Ted C. Hanf 2016 What Are We Talking About? Complementary and Alternative Medicine • Herbal Remedies • Homeopathic Remedies • Spiritual Remedies • Traditional “cures” How Prevalent is This ? • Mainstream usage among all groups • Geographic / Regional Variances • Cross Pollination by proximity and exposure • Social Networking and Media influences Council of Self-Insured Public Agencies Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 (c) Ted C. Hanf 2016 How Prevalent is This ? How Prevalent is This ? Gender Education College No College Men Women 0 20 40 Council of Self-Insured Public Agencies 60 (c) Ted C. Hanf 2016 © Ted C. Hanf ‐ 2016 80 100 0 20 40 Council of Self-Insured Public Agencies 60 80 100 (c) Ted C. Hanf 2016 1 Holistic Healing and its Interaction with Western Medicine – COSIPA – June 2016 How Prevalent is This ? How Prevalent is This ? Mexican Amer Native Amer Chinese Income Use CAM >50 K < 50K Dominican African Amer 0 0 20 40 Council of Self-Insured Public Agencies 60 80 20 40 60 80 100 100 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 (c) Ted C. Hanf 2016 Why Use CAM ? Why Use CAM ? • Pain /Back Problems • Menopause / Gynecological Problems • Rheumatology Related • Gastrointestinal • Sinus • Cognitive / Attention / Hyperactivity • Psychiatric / Neurological • Cancer • HIV • Asthma source: Institute of Medicine Council of Self-Insured Public Agencies Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 (c) Ted C. Hanf 2016 Most Commonly Prescribed Drugs Most Commonly Used OTC • Hydrocodone • Zocor • Lisiniopril • Synthroid • Norvasc • Prilosec • Azithromycin • Cough/Cold • Analgesics • Antacids • Laxatives • Antidiarrheal source: Daily Rx News 4‐17‐14 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 © Ted C. Hanf ‐ 2016 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 2 Holistic Healing and its Interaction with Western Medicine – COSIPA – June 2016 Why Does This Concern Us? Why Does This Concern Us? • High Percentage of CAM users do not report self‐ treatment to their primary treating physician • “Herbal” and “Natural” products are not regulated • • • • • • 61% 60% 31% 20% 15% 2% Not important Dr. never asked None of Dr’s business Dr. wouldn’t understand Dr. wouldn’t approve Dr. might refuse to treat Council of Self-Insured Public Agencies • Dosages and quality of ingredients varies widely • Teas, energy drinks, vitamins, soft drinks, dietary and food supplements from gym or “As Seen on TV” Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 (c) Ted C. Hanf 2016 Echinacea • Has life threatening interactions with: • • • • • • Acetaminophen Acyclovir Many statin drugs Cipro and other floxacin ABX Colchicine and close to 100 other commonly prescribed drugs Council of Self-Insured Public Agencies Source: National Center for Health Statistics, 2004 (c) Ted C. Hanf 2016 Echinacea (c) Ted C. Hanf 2016 Echinacea • Often used to strengthen the immune system, boost resistance to colds, flu, infections • May depress CD+4 levels and increase HIV replication • Affects hepatotoxicity used with drugs that raise liver enzyme levels • Affects drug levels of Anti‐Retroviral drugs taken for HIV and Hepatitis C • May depress CD+4 levels and increase HIV replication • May decrease activity of immunosuppressant drugs used in transplant and auto immune diseases Source: Drug‐Herb Interactions, Lippencott Williams & Wilkins 2003 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 © Ted C. Hanf ‐ 2016 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 3 Holistic Healing and its Interaction with Western Medicine – COSIPA – June 2016 Ginseng Ginseng • Affects the action of many drugs • Also an ingredient in many “energy” drinks • Digoxin – causes false level readings on testing • Furosemide, HCTZ – decreases effectiveness of diuretics used for high blood pressure • Haldol (haloperidol) increases CNS stimulation Source: Drug‐Herb Interactions Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 Gingko ( Gingko biloba) • Contains a substance that interferes with blood platelet activity and amplifies the effects of blood thinners • • • • • Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 Gingko ( Gingko biloba) • Affects the action of many drugs • Wellbutrin ‐ lowers seizure threshold Warfarin Coumadin Heparin Aspirin Fish‐Oil • Flagyl ‐ lowers seizure threshold, increases the risk of seizure • NSAIDS ‐ increases bleeding risk Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 Garlic St. John’s Wort • Used to prevent infection • Touted for having cancer prevention properties • Increases risk of bleeding • Used for mild to moderate depression • Inhibits effect of Warfarin, Digoxin in CVD • Significant Effect on SSRI psychotherapeutic drugs • Augments effect of MAOI psychotherapeutic drugs Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 © Ted C. Hanf ‐ 2016 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 4 Holistic Healing and its Interaction with Western Medicine – COSIPA – June 2016 St. John’s Wort St. John’s Wort • Affects the action of many drugs: • Must not be taken with MAOI antidepressants • If taking SSRI, must wait 4‐5 weeks before starting MAOI to avoid side effects • Furoxone, Marplan, Nardil • May cause extreme fever ( 104+F) • Has same properties as SSRI antidepressants • Celexa, Lexapro, Prozac, Paxil, Zoloft Council of Self-Insured Public Agencies • Seizure or death if taken with MAOI Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 Kava ( Kava Kava) (c) Ted C. Hanf 2016 Kava • Serious Drug Interactions: • Prevalent use among Pacific Islanders • Mood elevator, enhances wellbeing and contentment • Elavil – coma • Lipitor – liver damage • Wellbutrin – seizure and coma • Taken for anxiety and insomnia Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 Kava Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 YAWN !!! • Cannot combine with • Many statin drugs ‐ Lipitor, Pravachol, Crestor, Zocor • TCA, MAOI, SSRI, Benzodiazapine Antidepressants • Valerian Root tea ( contains benzodiazapines) Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 © Ted C. Hanf ‐ 2016 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 5 Holistic Healing and its Interaction with Western Medicine – COSIPA – June 2016 Yohimbe SEX • Sexual enhancer sales are soaring (now that I have your attention !!) Council of Self-Insured Public Agencies Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 Sexual Enhancement Supplements (c) Ted C. Hanf 2016 Sexual Enhancement Supplements Sales are soaring $ Million • Sexual enhancer supplements are everywhere 400 100 2001 2006 Source: Nat Bus Journal October 2007 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 Sexual Enhancement Supplements Sexual Enhancement Supplements • Sexual enhancer supplements are everywhere • You pay your money and you take your chances www.youtube.com/watch?v=q1eR7LXKEV0 accessed 5/14/16 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 © Ted C. Hanf ‐ 2016 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 6 Holistic Healing and its Interaction with Western Medicine – COSIPA – June 2016 Sexual Enhancement Supplements Yohimbe • FDA lab tests found that nearly 300 products contain undisclosed drug ingredients Active ingredient in Viagra, Cialis and Levitra. • Ingredient in many “herbal sex enhancers” • Samples also contained combinations of undisclosed ingredients or excessively high doses Source: http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm465024.htm Council of Self-Insured Public Agencies • Traditionally used in Africa as aphrodisiac source: NCCAM – nccam.nih.gov/health/supplement‐safety Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 (c) Ted C. Hanf 2016 Yohimbe Sexual Enhancement Supplements • High Blood Pressure + Increased Heart Rate • Anxiety + Sleeplessness • Dangerous combined with tricyclics and phenothiazines Source: NCCAM – nccam.nih.gov/health/supplement‐safety Council of Self-Insured Public Agencies • Captopril • Naproxen • Furosemide • Dexamethasone • Folic Acid • Loratadine • No prescription needed Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 (c) Ted C. Hanf 2016 Food and Beverages Food and Beverages • Grapefruit Energy Drinks • Blocks enzyme to metabolize Medication. Drug levels too high • Blocks absorption in intestine. Drug levels too low • Affects therapeutic effect of : Benzodiazepines Anti‐migraine drugs Statins Codeine Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 © Ted C. Hanf ‐ 2016 Opioids Antiretrovirals • ER visits due to use • Deaths linked to use • Sales continue to rise • Popular with Millenials Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 7 Holistic Healing and its Interaction with Western Medicine – COSIPA – June 2016 Food and Beverages Take Away Message • Drs., Lawyers, and Examiners shouldn’t just ask: “Are you taking any prescription or over the counter medicine?” • That is a totally meaningless question • Ask specifically about teas, herbs, food supplements, additives, over the counter, healing practices, traditional remedies Council of Self-Insured Public Agencies Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 (c) Ted C. Hanf 2016 Take Away Message Take Away Message • Ask about remedies or drugs acquired by travelers or sent by relatives from other countries • Understand how therapeutic agents are perceived and how and where they are obtained. • Know the different forms that “treatment” can take. • Speak in terms of “remedies” not drugs or prescription medicines Council of Self-Insured Public Agencies Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 (c) Ted C. Hanf 2016 Resources Resources National Center for Complementary and Alternative Medicine You NCCAM.NIH.GOV Your Friends Your Relatives Food and Drug Administration Your colleagues FDA.GOV Your instincts Centers for Disease Control and Prevention PROBE RELENTLESSLY UNTIL YOU HAVE AN ANSWER CDC.gov Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 © Ted C. Hanf ‐ 2016 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 8 Holistic Healing and its Interaction with Western Medicine – COSIPA – June 2016 The world is full of obvious things which nobody by any chance ever observes THANK YOU FOR YOUR ATTENTION Ted C. Hanf J.D., M.P.H. Kegel, Tobin & Truce APC Tel: 213‐380‐3880 Fax: 213‐383‐8346 E‐mail: [email protected] Sherlock Holmes A. Conan Doyle , Hound of the Baskervilles Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 © Ted C. Hanf ‐ 2016 Council of Self-Insured Public Agencies (c) Ted C. Hanf 2016 9