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2004: 3-Tier Medication Guide of Commonly Prescribed Drugs The designation of drugs in the following categories is for reference only and is not a clinical comparison. Drug placement does not establish clinical comparability of products in individual situations. This list provides examples within categories and is not comprehensive. DRUG CLASS Tier 1 Tier 2 (lowest member co-payment) ALLERGY Antihistamines (Oral) Antihistamine/ Decongestant Combinations Intranasal: Steroids/ Antihistamines/ Miscellaneous ALZHEIMER’S ARTHRITIS ASTHMA Inhaled Beta Agonists/ Inhaled Respiratory Agents (miscellaneous) Inhaled Steroids Leukotriene Inhibitors Respiratory Drugs (oral) ATTENTION DEFICIT DISORDER BLOOD Anticoagulants Antiplatelet Anemia CANCER CARDIOVASCULAR / HEART ACE Inhibitors (high blood pressure) Angiotensin II Receptor Blockers Tier 3 (highest member co-payment) clemastine, cyproheptadine, diphenhydramine, hydroxyzine Numerous generics No drugs listed at this time Allegra, Clarinex, Zyrtec No drugs listed at this time Allegra-D, Optimine, Rynatan SA, Semprex-D, Trinalin, Zyrtec-D flunisolide, ipratropium nasal spray Beconase AQ, Flonase, Nasonex, Rhinocort AQ No drugs listed at this time Aricept Astelin, Atrovent Nasal Spray, Nasacort, Nasacort AQ, Nasarel, Nasalide, Tri-Nasal, Vancenase, Vancenase AQ, Vancenase DS Cognex, Exelon, Reminyl azathioprine, cyclophosphamide, gold, hydroxychloroquine, methotrexate, penicillamine, sulfasalazine No drugs listed at this time Arava§, Enbrel§, Humira§, Kineret§, Rheumatrex albuterol, cromolyn sodium, metaproterenol solution Atrovent Inhaler, Combivent, Intal, Pulmozyme, Serevent Diskus Advair, Foradil, Maxair, Maxair Autohaler, Proventil, Proventil HFA, Tilade, Tornalate, Ventolin, Xopenox No drugs listed at this time Azmacort, Beclovent, Flovent, Pulmicort Singulair (Tier 2 if history criteria met) No drugs listed at this time Advair, Aerobid, Aerobid M, QVAR, Vanceril, Vanceril DS Accolate, Zyflo Alupent, Brethine, Proventil SA, T-Phyl, Theo-Dur, Uniphyl, Volmax Adderall, Adderall XR, Concerta, Dexedrine, Dexedrine Spansules, Dextrostat, Focalin, Metadate CD, Ritalin, Ritalin LA, Strattera§ No drugs listed at this time albuterol, metaproterenol, theophylline dextroamphetamine, methylin, methylin ER, methylphenidate No drugs listed at this time heparin, warfarin dipyridamole No drugs listed at this time methotrexate, tamoxifen Coumadin Agrylin, Plavix Epogen§, Neupogen,Procrit§ All brands are Tier 2 Arixtra, Fragmin, Inohep, Lovenox Aggrenox, Pletal, Ticlid, Trental Aranesp§ No drugs listed at this time captopril, enalapril, lisinopril, moexepril Altace No drugs listed at this time Avapro\, Diovan Accupril§, Aceon§, Capoten§, Lotensin§, Mavik§, Monopril§\, Prinivil§, Univasc§, Vasotec§, Zestril§ Atacand§, Benicar§, Cozaar§, Micardis§, Teveten§ amiodarone, digoxin, disopyramide, mexiletine, procainamide, quinidine, sotalol cholestyramine, clofibrate, gemfibrozil, lovastatin Betapace AF, Lanoxin, Rythmol, Tonocard (high blood pressure) Antiarrhythmics (for normal heart rhythm) Antihyperlipidemics (high cholesterol) Antihypertensive Combinations (high blood pressure) Beta Blockers (high blood pressure) Calcium Channel Blockers 1 bisoprolol/hydrochlorothiazide, captopril/ hydrochlorothiazide enalapril/hydrocholrothiazide lisinopril/hydrochlorothiazide acebutolol, atenolol, bisoprolol, labetolol, metoprolol, nadolol, propranolol, propranolol solution, pindolol, timolol diltiazem, diltiazem-XR, nicardipine, nifedipine, Taztia XT, verapamil, verapamil (SR) Lipitor\, Lofibra, Niaspan, Pravachol\, Tricor, Zetia (Tier 2 if history criteria are met) Avalide, Diovan HCT Coreg, Toprol XL 25mg, 50mg\, 100mg, 200mg Norvasc: Tier 2 if age 55 or older and on concurrent ACE/ARB therapy or on nitrate therapy Betapace, Cordarone, Mexitil, Norpace CR, Procan, Procanbid, Pronestyl, Quinidex, Quiniglute, Tambocor, Tikosyn Altocor, Advicor, Colestid, Crestor, Crestor 10mg\, 20mg\, 40mg\§, Lescol§, Lescol XL§, Mevacor, Pravigard, Questran, Welchol, Zocor\§ Accuretic§, Atacand HCT§, Benicar HCT§, Capozide§, Hyzaar§, Lexxel, Lopressor HCT, Lotensin HCT§, Lotrel, Micardis HCT§, Monopril HCT§, Prinzide§, Tarka, Teczem, Tenoretic, Tevetan HCT§, Uniretic§, Vaseretic§, Zestoretic§, Ziac Corgard, Inderal LA, Innopran XL, Kerlone, Levatol, Lopressor, Sectral, Tenormin, Trandate, Visken, Zebeta Adalat CC, Calan, Calan SR, Cardene, Cardene SR, Cardizem, Cardizem CD, Cardizem LA , Covera, Covera HS, Dilacor XR, Dynacirc, Dynacirc CR, Plendil, Procardia XL, Sular, Tiazac, Verelan, Verelan PM List Subject to Change Co-payment/Coinsurance for each tier is based on the specific rider chosen by the employer group. The majority of benefits include additional member payment when a brand drug is used and a generic equivalent is available. Brand drugs not listed are considered Tier 3. All compounds are considered Tier 3. § = Requires Prior Authorization \ = Half Tablet opportunity: Certain strength tablets may be split to obtain lower dosage and reduce member out-of-pocket cost V = May be Tier 2 for select prescribers/diagnoses B-1530y4 Rev. 1/21/04 1 DRUG CLASS Diuretics Nitrates (angina) Tier 1 (lowest member co-payment) amiloride, furosemide, hydrochlorothiazide (HCTZ), indapamide, spironolactone, triamterene/HCTZ Numerous generics Tier 2 Tier 3 No drugs listed at this time (highest member co-payment) Aldactone, Bumex, Demadex, Dyazide, Dyrenium, Hydrodiuril, Hygroton, Lozol, Maxzide, Zaroxolyn No drugs listed at this time Deponit, Imdur, Ismo, Monoket, Nitrek, Nitrodisk, Nitro-Dur, Transderm-Nitro K-Dur, K-Lyte, K-Tab, Micro-K, Slow K Cylert, Desoxyn, Dexedrine, Dexedrine Spansules, Provigil 100mg§, Provigil 200mg§\, Xyrem§ Potassium Supplements CENTRAL NERVOUS SYSTEM COUGH / COLD Antitussives and Expectorants potassium chloride generics pemoline Urocit-K No drugs listed at this time benzonatate, guiafenesin products, hydrocodone products No drugs listed at this time Amibid LA, Duratuss G, Humabid LA, Tussionex Antitussive Combinations gauifenesin/codeine, hydrocodone/homatropine, promethazine/codeine No drugs listed at this time Genesin DM, Guaituss AC, Histussin, Histussin HC, Hycodan, Hycotuss, Phenergan w/codeine, Rondec-DM benzoyl peroxide, clindamycin, erythromycin, erythromycin/benzoyl peroxide, isotretinoin, sulfacetamide, tretinoin products, tetracycline, others bacitracin/polymyxin, erythromycin, gentamycin, neomycin/polymyxin, tobramycin, others ketoconazole cream, mycostatin, triamcinolone/nystatin, betamethasone/clotrimazole betamethasone, clobetasol, dexamethasone, fluocinolone, fluocinonide, hydrocortisone, triamcinolone Metrocream, Metrogel Accutane, A/T/S, Avita, Azelex, BenzaClin, Benzamycin, Cleocin T, Desquam E, Differin, Emgel, Finacea, Finevin, Klaron, Novacet, Retin-A, Sulfacet-R, T-stat Bactroban Emgel, Noritate, Silvadene Nizoral Shampoo Exelderm, Loprox, Lotrimin, Lotrisone, Mentax, Mycelex, Mycolog II, Naftin, Nizoral Cream, Oxistat, Spectazole Aclovate, Cloderm, Cordran, Cordran Tape, Cutivate, Cyclocort, Decadron, Desowen, Diprolene/AF, Elocon, Florone/E, Halog/E, Locoid, Medrol Dose Pack, Pandel, Temovate, Psorcon/E, Topicort, Ultravate, Uticort selenium sulfide Dovonex, Drithocreme DERMATOLOGY Topical/Oral Acne Products Topical Antibiotics Topical/Combination Antifungals Topical/ Oral Steroids Topicals: Psoriasis/Eczema DIABETES Blood Glucose Supplies Insulin Capex Shampoo, Florinef Capitrol, Elidel, Protopic, Selsun, Soriatane (oral), Tazorac Diabetic benefit and/or DME benefit applies: Preferred Meters are: Accu-check Active, Accu-check Advantage, Accu-check Compact, Accu-check Complete, One Touch Sure Step, One Touch Ultra DIABETIC BENEFIT APPLIES FOR ALL INSULINS If Diabetic benefit DOES NOT apply please refer to the following tier classifications: No drugs listed at this time Oral Hypoglycemics Humalog, Humulin, Lantus, Novolin, No drugs listed at this time Novolog DIABETIC BENEFIT APPLIES FOR ALL ORAL HYPOGYLCEMICS If Diabetic benefit DOES NOT apply, please refer to the following tier classifications: glipizide, glyburide, metformin Actos, Amaryl, Avandia, Glyset, Prandin, Precose, Starlix, Glucotrol XL Cipro HC and Floxin Otic only for children <11 years of age Avandamet, Diabeta, Glucophage, Glucophage XR, Glucotrol, Glucovance, Glynase, Metaglip, Micronase Aurulgan, Cerumenex, Cortisporin, Pediotic, Vosol, Vosol HC EAR Numerous generics ENTERAL FORMULAS EYE Ophthalmic Anti-Inflammatory Multiple products available§ PKU Formulas§ All branded enteral products§ dexameth, dexa/neo, fluorometholone, flurbiprofen, prednisolone cromolyn sodium Lotemax, Voltaren, PredForte FML Forte, Ocufen, Vexol Optivar, Zaditor, Acular, Acular PF Ciloxan, Ocuflox Alamast, Alocril, Alomide, Alrex, Emadine, Livostin, Opticrom, Patanol Chibroxin, Quixin, Vigamox, Zymar Vira A, Viroptic FML-S, Poly-Pred Vitrasert, Vitravene HMS, Pred-G, TobradexV Ophthalmic Antiallergics Ophthalmic Antiinfectives Ophthalmic Antivirals Ophthalmic Combinations 2 bacitracin, bac/poly/neo, neosporin, polysporin, erythro, gent, sodium sulfacetamide, TMP/pol, tobra, others No drugs listed at this time neomycin, neomycin/polymixin, dexamethasone sodium phosphate solution, etc. List Subject to Change Co-payment/Coinsurance for each tier is based on the specific rider chosen by the employer group. The majority of benefits include additional member payment when a brand drug is used and a generic equivalent is available. Brand drugs not listed are considered Tier 3. All compounds are considered Tier 3. § = Requires Prior Authorization \ = Half Tablet opportunity: Certain strength tablets may be split to obtain lower dosage and reduce member out-of-pocket cost V = May be Tier 2 for select prescribers/diagnoses B-1530y4 Rev. 1/21/04 2 DRUG CLASS Glaucoma Tier 1 Tier 2 (lowest member co-payment) carbachol, carteolol, dipivefrin, levobunolol, pilocarpine, timolol, timolol XE Alphagan P, Lumigan, Trusopt, Xalatan No drugs listed at this time GROWTH HORMONES allopurinol, colchicine, colchicine/probenecid, probenecid, sulfinpyrazone No drugs listed at this time HEPATITIS No drugs listed at this time HIV No drugs listed at this time IMMUNE SYSTEM azathioprine, cyclosporine Copegus§, Peg Intron§, Pegasys§, Rebetol§ All brands are Tier 2- Combivir, Crixivan, Epivir, Fortovase, Norvir, Viracept, Viramune, Zerit Cellcept, Neoral, Prograf, Rapamune, Sandimmune, Sandostatin GOUT INFECTIONS: BACTERIAL, FUNGAL, VIRAL amoxicillin, Antibiotics amoxicillin/clavulanate, ampicillin, dicloxacillin, cefaclor, cefadroxil, cefuroxime tablets, cephalexin, doxycycline, erythromycins, ofloxacin, penicillin, others griseofulvin, nystatin Antifungal Drugs (Oral) Antiviral Drugs MALARIA MEN’S HEALTH BPH Agents (prostate) Erectile Dysfunction Hormones Oral Androgens MENTAL HEALTH Antidepressants acyclovir, amantadine, rimantadine chloroquine, hydroxychloroquine, quinine Nutropin§, Nutropin AQ§, Protropin§ Tier 3 (highest member co-payment) Azopt, Betagan, Betimol, Betoptic, Betoptic-S, Cosopt, Iopidine, Ocupress, Optipranolol, Pilopine gel, Propine, Rescula, Timoptic, Timoptic XE, Travatan Zyloprim Genotropin§, Humatrope§, Norditropin§, Saizen§, Serostim§, Tev-tropin§ Infergen, Intron-A, Rebetron, Roferon A No drugs listed at this time Imuran Any brand when prescribed for patients <11 years of age Augmentin, Augmentin XR, Avelox, Biaxin, Ceclor CD, Cedax, Ceftin, Cefzil, Cipro, Cipro XR, Cleocin, Dynabac, Floxin, Levaquin, Lorabid, Macrobid, Maxaquin, Monurol, Noroxin, Omnicef, PCE, Penetrax, Spectracef, Suprax, Tequin, Tobi, Trovan, Vantin, Vancocin, Zagam, Zithromax, Zyvox§ Diflucan 150mg, Griseofulvin Suspension, Lamisil tablets§ Hepsera, Valtrex Cytovene (Tier 2 for CMV retinitis only) Lariam Diflucan, Penlac§, Sporanox§, Vfend doxazosin, prazocin, terazosin Flomax (Tier 2 after failure to generic) yohimbine testosterone No drugs listed at this time Viagra§ Android, Depo-Testosterone Casodex, Eulexin amitriptyline, amoxipine, desipramine, doxepin, fluoxetine, imipramine, nortriptyline, paroxetine, protriptyline, trazodone Celexa 40mg\, Zoloft 100mg\, Paxil 30mg, 40mg\, Paxil suspension Effexor, Effexor XR: Tier 2 only if Denavir, Famvir, Flumadine, Relenza§, Symmetrel, Tamiflu, Valcyte, Zovirax Daraprim, Fansidar, Malarone, Plaquenil Avodart, Cardura, Hytrin, Proscar Caverject, Edex, Levitra§, Muse Androderm, Androgel, Testoderm No drugs listed at this time Celexa 10mg, 20mg\, Desyrel, Elavil, Lexapro\, Luvox, Nardil, Pamelor, Parnate, Paxil 10mg, 20mg\, Paxil CR, Prozac§, Prozac Weekly§, Remeron, Sarafem§, Sinequan, Surmontil, Tofranil, Zoloft 25mg, 50mg Serzone, Surmontil, Wellbutrin history criteria are met Wellbutrin SR, Welllbutrin XL: Tier 2 only if <13 years of age or history criteria are met Antipsychosis Sedatives/Hypnotics/ Anxiety MIGRAINE clozapine, haloperidol, trifluoperazine, thioridazine, others benzodiazepines (alprazolam, clonazepam, diazepam, triazolam), hydroxyzine ergotamine, isometheptene/dichlor/APAP MULTIPLE SCLEROSIS No drugs listed at this time OSTEOPOROSIS No drugs listed at this time 3 Abilify, Geodon, Risperdal, Seroquel, Zyprexa Clozaril, Haldol, Mellaril, Navane, Prolixin, Stelazine, Thorazine, Trilafon High dose requires prior authorization Ambien (only for aged >65) Ativan, Buspar, Serax, Sonata, Valium, Xanax Depakote ER, Maxalt, Maxalt MLT, Migranal, Imitrex 100mg & 50mg tablets, Imitrex nasal spray and injection Amerge, Axert, Frova, Imitrex 25mg tablets, Relpax, Zomig, Zomig ZMT Betaseron, Copaxone Actonel, Actonel Weekly, Evista, Fosamax, Fosamax Weekly Avonex, Rebif Didronel, Forteo§, Skelid, Miacalcin Nasal List Subject to Change Co-payment/Coinsurance for each tier is based on the specific rider chosen by the employer group. The majority of benefits include additional member payment when a brand drug is used and a generic equivalent is available. Brand drugs not listed are considered Tier 3. All compounds are considered Tier 3. § = Requires Prior Authorization \ = Half Tablet opportunity: Certain strength tablets may be split to obtain lower dosage and reduce member out-of-pocket cost V = May be Tier 2 for select prescribers/diagnoses B-1530y4 Rev. 1/21/04 3 DRUG CLASS Tier 1 Tier 2 (lowest member co-payment) PAIN / INFLAMMATION Muscle Relaxants NSAIDs Pain Relievers (narcotic) PARKINSON’S SEIZURE / PAIN SMOKING DETERRENTS STOMACH / INTESTINAL Antiemetics (for nausea) Antispasmotic Drugs Digestants Inflammatory Bowel Irritable Bowel Syndrome Ulcer/Heartburn baclofen, methocarbamol, carisoprodol, cyclobenzaprine, others diclofenac, fenoprofen, flurbiprofen, ibuprofen, indomethacin, ketoprofen, nabumetone, naproxen, naproxen sodium, oxaprozin, piroxicam, salsalate, sulindac, tolmetin No drugs listed at this time acetaminophen/codeine, acetaminophen/propoxyphene, hydrocodone combinations, methadone, morphine (immediate & sustained release), others amantadine, anticholinergics, bromocriptine, carbidopa/levodopa, selegiline carbamazepine, clonazepam, phenytoin, valproic acid (highest member co-payment) No drugs listed at this time Norflex, Skelaxin, Zanaflex No drugs listed at this time Step Therapy applies: Arthrotec, Cataflam, Daypro, EC-Naprosyn, Lodine XL, Mobic, Naprelan, Oruvail, Ponstel, Relafen, Toradol, Voltaren XR No drugs listed at this time Step Therapy applies: Vioxx \, Vioxx Suspension, Bextra\, Celebrex (Patient must have failed a trial of Vioxx or Bextra prior to Celebrex approval) Avina, Avinza, Duragesic, Kadian, MS Contin, MSIR, Norco, Oramorph SR, OxyIR, Ultram, Zydone Duragesic, Oxycontin (Tier 2 for chronic, intractable pain) Comtan, Permax, Requip Cogentin, Dopar, Eldepryl, Larodopa, Lodosyn, Mirapex, Parlodel, Sinemet CR, Tasmar Depakote, Dilantin, Felbatol, Gabitril, Keppra, Klonopin, Neurontin, Tegretol XR, Trileptal, Zonegran, Zarontin, others No drugs listed at this time No drugs listed at this time No drugs listed at this time No drugs listed at this time Habitrol, Nicotrol , Zyban meclizine, prochlorperazine, others clidinium products, dicyclomine, hyoscyamine, oxybutynin, others pancrealipase Zofran Anzemet, Kytril, Marinol, Transderm-SC Urecholine Detrol, Detrol LA, Ditropan, Ditropan XL, Levsin, Levsinex, Oxytrol Patch, Urispas No drugs listed at this time sulfasalazine, hydrocortisone enema No drugs listed at this time cimetidine, famotidine, ranitidine No drugs listed at this time WEIGHT MANAGEMENT omeprazole§, Prilosec OTC metoclopramide, sucralfate levothyroxine, levoxyl, levothroid, PTU diethylpropion WOMEN’S HEALTH Hormones Oral Transdermal Fertility Drugs* cycrin, estradiol, medroxyprogesterone estradiol patch clomiphene citrate THYROID Tier 3 *Not all prescription drug benefits provide coverage Cotazym, Cotazym S, Creon, Kutrase, Pancrease, Pancrease MT, Ultrase MT, Viokase, Zymase Asacol, Canasa, Cortenema, Pentasa, Rowasa enema No drugs listed at this time No drugs listed at this time No drugs listed at this time Prevacid, Protonix Cytotec Cytomel, Synthroid, Tapazole LamictalV , TopamaxV, ZonegranV Azulfidine (enteric coated), Colazal, Dipentum, Entocort EC Lotronex§, Zelnorm§ Axid, Pepcid, Tagamet, Zantac Helidac, Prevpac, Tritec Aciphex§ Nexium§, Prilosec§ Carafate Armour Thyroid, Thyrolar, Unithroid No drugs listed at this time Adipex-P, Adipost, Bontril-SR, Didrex, Meridia§, phentermine, Xenical§ Estratest, Estratest HS, Premarin, Premphase, Prempro, Prometrium Climara No drugs listed at this time Activella, Cenestin, Estrace, Estratab, FemHRT, Menest, Ogen, Ortho-Prefest Alora, Combipatch, Estraderm, Vivelle/Dot, Clomid, Crinone, Fertinex§, Follistim§, Gonal-F§, Humegon§, Metrodin§, Ovidrel§, Pergonal§, Repronex§ Alesse, Brevicon, Cylessa, Demulen, Desogen, Estrostep, Estrostep FE, Jenest, Loestrin, Loestrin FE, Lo-Ovral, Mircette, Nordette, Norinyl, Nor QD, NuvaRing, Ovcon, Ovral, TriNessa, Trinorinyl, Triphasil, Tri-Sprintec Apri, Aviane, Camila, Cryselle, Levlen, Levlite, Modicon, Enpresse, Jolivette, Kariva, Ortho-Cept, Ortho-Cyclen, *Not all prescription drug benefits Lessina, Levora, Low-Ogestrel, Ortho Evra, Ortho Micron, provide coverage Microgestin FE, Necon, Nelova, Ortho-Novum, Ortho Tri-Cyclen Lo, Nora B, Nortrel, Ogestrel, Tri-Levlen, Yasmin Ortho Tri-Cyclen, Portia, Sprintec, Trivora, Zovia Miscellaneous Tier 2 agents: DDAVP tablets, Diamox Sequels, Elmiron, Epipen, Epipen Jr., Evoxac, Glucagen, Mestinon, Metrogel Vaginal, Metrolotion, Phoslo, Premarin Vaginal, Pulmozyme, Renagel, Rilutek, Salagen, Stimate, Synarel Oral Contraceptives* 4 List Subject to Change Co-payment/Coinsurance for each tier is based on the specific rider chosen by the employer group. The majority of benefits include additional member payment when a brand drug is used and a generic equivalent is available. Brand drugs not listed are considered Tier 3. All compounds are considered Tier 3. § = Requires Prior Authorization \ = Half Tablet opportunity: Certain strength tablets may be split to obtain lower dosage and reduce member out-of-pocket cost V = May be Tier 2 for select prescribers/diagnoses B-1530y4 Rev. 1/21/04 4