Download Curriculum Vitae

Curriculum Vitae
Name: Mohammad Reza
Surname: Aghasadeghi
Address: Hepatitis & AIDS Dep. Pasteur Institute of Iran, Pasteur St., Tehran, Iran
Tel/fax: +98-21-66969291
E-mail: [email protected]
Nationality: Iranian
Date of birth: 21, March, 1967 .
Place of Birth : Tehran .
M arital status: Married .
Position : From 2007, Head of department of Hepatitis & AIDS( Associated professor).
Education:
2001 to 2007: Ph.D. in Medical Biotechnology, Pasteur Institute, Tehran, Iran.
1994-1997: M.Sc. in Medical Microbiology, Shahid Beheshti University of Medical
Sciences. Tehran, Iran .
1989-1993: B.Sc. in Microbiology, Tehran university .Tehran, Iran.
M .Sc. thesis: Antimicrobial effects of Capsicum annum fruit extract In vitro
Ph.D. thesis: Expression and purification of rHCV-CoreAg in Native and Truncated
forms, Production of mAb against them and evaluation and characterization of
product.
Advanced courses taken during Ph.D.
Practical microbiology, advanced biochemistry, Genetic engineering, Quality control of
biological products, Advanced Immunology, Molecular Genetics, Advanced Practical
Biochemistry.
Advanced courses taken during M .sc.
Advanced Bacteriology, Medical virology, Antimicrobial Agents, Hematology, Medical parasitology, Microbial physiology, Laboratory Animals.
Professional Positions:
2012 to 2015 : Director of Virology Group
2007 to date: Head of Hepatitis and AIDS Department, Pasteur Institute of Iran,
Tehran, Iran
2004 to 2007: Research Assistant (member of educational board) in Hepatitis and
AIDS Department, Pasteur Institute of Iran, Tehran, Iran
2002 - 2004: Researcher in Hepatitis and AIDS Department, Pasteur Institute of Iran,
Tehran, Iran
1998-2002: Researcher in B.C.G unit – Pasteur Institute, Tehran, Iran.
Principal Supervisor of Ph.D. thesis entitled: Cloning and expression of HCV ARFPs
and their immunogenic characterization in BALB/c mice.
Principal Supervisor of master thesis entitled:
1-Design, cloning, expression and evaluation of cystein derivatives of native
streptokinase (SK) and truncated SK.
2- HBV genotyping of HBsAg carrier in intravenous drug user prisoners of Tehran
province by RFL-PCR in large scale studies.
3-Construction of recombinant BCG That secretes multiepitopes containing E2,core and
NS3 epitopes to achieve an efficient and safe HCV vaccine.
Co-supervisor (advisor) of Ph.D. thesis entitled:
1-Design and evaluation of novel chimeric streptokinase molecules with enhanced
thrombolytic activity and fibrin specific properties.
2- Conjugated inolenic acid biosynthesis by propionibacterium acnes linoleic acid
isomerase-displaying yeast in aqueous and organic media.
3- Preparation of Cysteine Analogs of Erythropoietin in CHO and Analysis of Their
Pegylation
4-Evaluation of responses towards H2d core epitope of HCV in BALB/c mice immunized
by recombinant BCGs harboring the native gene or a polytopic construct.
5- In silico linear B-cell epitopes prediction of extra membrane motif of the human B
lymphocyte CD20 antigen and preparation of murine monoclonal antibody against them.
6- Study on the effect of HCV capsid proteinexpression on transcriptional levels of IRF1, ISG20 and ISG56 genes in HepG2 cell line in the presence or absence of alpha
interferon.
Projects:
Comparative study on mutations associated with Lamivudine resistance in HBV and
HBV/HIV co-infected patient
Designing, constructing and evaluation of bicistronic plasmid capable of simultaneous
expression of antigen and IL18/Ig adjuvant.
Evaluation of anti-HIV-1 activities of synthetic iron chelator , Pyridinone compounds.
Study on specific cellular and humoral responses against HIV-1 using the Archeasome
adjuvant originated from Methanobrevibacter smithii Balb/c
Design and Evaluation of Immunological characteristic of mzNL4-3-NS3 in BALB/c
mice
Design and physicochemical evaluation of pegilated nano chitosan loaded with
Ribavirin
Study on Immunogenesis of expressed HCV core E/E2 protein from baculovirus
expression system in Balb/c mice.
Pattern of HIV drug resistance to existing antiviral drug in Iran,Shiraz
Design and construction of DNA vaccine / subunit vaccine for effective induction of antiCMV cellular and humoral response
Synthesis of curcumin conjugated PEG-citrate dendrimer-G2 in order to evaluate its
nano-chemical and solubility and evaluation of its anti HIV-1 effects .
Localization, validation and production of Viral Hepatitise B & C molecular diagnostic
kits.
Professional Experience:
1. Familiar with different techniques of DNA-technology (DNA / RNA extraction
methods, Cloning, PCR, Blotting techniques, etc.).
2. Familiar with different Immunological, Biochemical and Microbiological techniques
(ELISA, Electrophoresis, Chromatography, Recombinant Protein Purification, Bacterial
and mammalian cell culture and expression systems, etc.).
Books:
Short Guide to Hepatitis C ,2011
Translated
Brucellosis Vaccines: An Overview ,2012
Seyed Davar Siadat, A Sharifat Salmani, Mohammad Reza Aghasadeghi
Publications:
1- Romani B, Shaykh Baygloo N, Aghasadeghi M R, Allahbakhshi E. HIV-1 Vpr enhances proteasomal
degradation of MCM10 through the Cul4-DDB1[VprBP] E3 ubiquitin ligase to induce G2/M cell cycle arrest.
J Biol Chem. 2015 Jun 1. pii: jbc.M115.641522.
2- Saleh T, Bolhassani A, Shojaosadati SA, Aghasadeghi M R. MPG-based nanoparticle: An efficient delivery
system for enhancing the potency of DNA vaccine expressing HPV16E7. Vaccine. 2015 May 19. pii: S0264410X(15)00636-2. doi: 10.1016/j.vaccine.2015.05.015.
3- Memarnejadian A, Menbari S, Mansouri SA, Sadeghi L, Vahabpour R, Aghasadeghi M R, Mostafavi
E, Abdi M. Transmitted Drug Resistance Mutations in Antiretroviral-Naïve Injection Drug Users with Chronic
HIV-1 Infection in Iran. PLoS One. 2015 May 11;10(5):e0126955. doi: 10.1371/journal.pone.0126955.
eCollection 2015.
4- Ardestani MS, Fordoei AS, Abdoli A, Ahangari Cohan R, Bahramali G, Sadat SM, Siadat SD, Moloudian
H, Nassiri Koopaei N, Bolhasani A, Rahimi P, Hekmat S, Davari M, Aghasadeghi M R. Nanosilver based
anionic linear globular dendrimer with a special significant antiretroviral activity. J Mater Sci Mater
Med. 2015 May;26(5):5510. doi: 10.1007/s10856-015-5510-7. Epub 2015 Apr 17.
5- Fateh A, Aghasadeghi M R, Keyvani H, Mollaie HR, Yari S, Hadizade Tasbiti AR, Ghazanfari
M, Monavari SH. High resolution melting curve assay for detecting rs12979860 IL28B polymorphisms
involved in response of Iranian patients to chronic hepatitis C treatment. Asian Pac J Cancer
Prev. 2015;16(5):1873-80.
6- Saeideh Ebrahimi, Majid Sadeghizadeh, M ohammad Reza Aghasadeghi, Mehdi
Shafiee Ardestani, Mehrdad Behmanesh. One-step Synthesis of Anionic PEG-citrate G2 Dendrimer and
Evaluation of its Cytotoxicity in Two Cell Lines. Modares Journal of Medical Sciences: Pathobiology, Vol. 17
(2014-2015), No. 4, Pages: 13-24.
7- Elham Mohammadi,a Massoud Amanlou,b Seyed Esmaeil Sadat Ebrahimi,b Morteza Pirali Hamedani,b
Abdolkarim Mahrooz,c Bita Mehravi,d Baharak Abd Emami, M ohammad Reza Aghasadeghi, Ahmad
Bitarafan-Rajabi, Hamid Reza Pour Ali Akbarh and Mehdi Shafiee Ardestani. Cellular uptake, imaging and
pathotoxicological studies of a novel Gd[III]–DO3A-butrol nanoformulation. RSC Adv., 2014, 4, 45984–
45994.
8- M ohammad Reza Aghasadeghi, Mohammad Banifazl, Arezoo Aghakhani, Ali Eslamifar,
Rouhollah Vahabpour and Amitis Ramezani. No evidence for occult HBV infection in hepatitis
B vaccine non-responders. IRAN. J. MICROBIOL. Vol. 6, No 5 (October 2014), 350-353.
9- Mahtab Daneshvar, M ohammad Reza Agahsadeghi, Sanaz Mahmazi, Seyed Mehdi Sadat. The Effects of
Single Nucleotide Polymorphism of IL28B Gene (rs12979860) on Treatment Response to Pegylated
Interferon/Ribavirin in Iranian Patients with Hepatitis C. J Mazandaran Univ Med Sci 2014; 24(116): 4151(Persian).
10- Hajar Sirous, Rezvan Zabihollahi, M ohammad R. Aghasadeghi, Seyed Mehdi Sadat, Lotfollah Saghaie,
Afshin Fassihi. Docking studies of some 5-hydroxypyridine-4-one derivatives: evaluation of integrase and
ribonuclease H domain of reverse transcriptase as possible targets for anti-HIV-1 activity. Med Chem Res
2014.
11- Bahareh Rajaei, Seyed Davar Siadat, Nahid Sepehri Rad, Farzad Badmasti, Mohamad Reza Razavi,
M ohammad Reza Aghasadeghi, Raheleh Saboohi, Taraneh Rajaei, Arfa Moshiri, Mehdi Nejati and Ahmad
Reza Bahremand. Molecular Detection of AntimicrobialResistance Gene Cassettes Associated withClass 2
Integron in Salmonella Serovars Isolated in Iran. British Microbiology Research Journal 4(1): 128-137, 2014.
12- Saghi Sepehri, Sajjad Gharagani, Lotfollah Saghaie, M ohammad R. Aghasadeghi, Afshin Fassihi. QSAR
and docking studies of some 1,2,3,4-tetrahydropyrimidines: evaluation of gp41 as possible target for antiHIV-1 activity. Med Chem Res 2014
13-Bahareh Rajaei, Nahid Sepehri Rad, Farzad Badmasti, Mohamad Reza Razavi, M ohammad Reza
Aghasadeghi, Raheleh Saboohi1, Taraneh Rajaei, Arfa Moshiri and Seyed Davar Siadat. Multiple-Antibiotic
Resistance in Salmonella enterica Serovars Isolated in Iran Harboring Class 1 Integrons. British Microbiology
Research Journal 5(2): 186-193, 2015, Article no.BMRJ.2015.020.
14- Fatemeh ASHRAFI, Jalil Fallah MEHRABADI, Seyed Davar SIADAT, M ohammad Reza
AGHASADEGHI . Uropathogenic E.coli PapG Protein: The Expression and Immune Characterization in
Balb/C Mice. Journal of Applied Biological Sciences 8 (3): 79-84, 2014.
15- Dezfuli HT, Shahbazzadeh D, Eidi A, Bagheri KP, Pakravan N, Amini S, Aghasadeghi M R, Mahdavi M.
Induction of IFN-γ cytokine response against hepatitis B surface antigen using melittin. Gastroenterol Hepatol
Bed Bench. 2014 Spring;7(2):108-17.
16- Aghasadeghi MR, Delbaz SA, Sadat SM, Siadat SD, Ardestani MS, Rahimi P, Bolhassani A, Roudsari
RV, Bahramali G, Motevalli F, Davari M, Vakily H, Salmani AS, Nobari MB. Induction of Strong and
Specific Humoral and T-helper 1 Cellular Responses by HBsAg Entrapped in the Methanobrevibacter smithii
Archaeosomes. Avicenna J Med Biotechnol. 2014 Oct;6(4):238-45.
17- Siadat SD, Vaziri F, Eftekhary M, Karbasian M, Moshiri A, Aghasadeghi MR, Ardestani MS, Alitappeh
MA, Arsang A, Fateh A, Peerayeh SN, Bahrmand AR. Preparation and Evaluation of a New
Lipopolysaccharide-based Conjugate as a Vaccine Candidate for Brucellosis. Osong Public Health Res
Perspect. 2015 Feb;6(1):9-13. doi: 10.1016/j.phrp.2014.10.012. Epub 2014 Dec 18.
18- Ramezani A, Aghasadeghi MR, Ahmadi F, Razeghi E, Eslamifar A, Banifazl M, Sofian M, Bahramali G,
Hekmat S, Aghakhani A. Isolated anti-hbc and occult HBV infection in dialysis patients. Nephrourol Mon. 2014
Nov 30;7(1):e22674. doi: 10.5812/numonthly.22674. eCollection 2015.
19- Akram Tabatabaee, Seyed Davar Siadat, Seyed Fazllolah Mousavi, M ohammad Reza
Aghasadeghi. Determination of antigenic determinants in the C-terminal 311 amino acids of
Haps adhesion from Nontypeable Haemophilus influenza. Medical Science Journal of Islamic
Azad Univesity-Tehran Medical Branch.2014;24(2): 92-105
20- Narges Karimi, M ohammad Reza Aghasadeghi, Parichehr Yaghmaei, Hadi Fathi
Moghaddam, Nasser Nassiri-Koopaei, Hamid Moloudian, Saleh Najafi, Seyed Ataaollah
Shandiz, Mehdi Shafiee Ardestani. Anionic Linear Globular Dendrimer-G2-Ciprofloxacin NanoConjugate: Novel Agent against Wilson Disease Cell Model. Letters in Drug Design &
Discovery.2014;11(7):908-916
21- Fahimeh Bagheri Amiri, Mohammad Mehdi Gouya, Mahnaz Saifi, Mehdi Rohani, Payam
Tabarsi, Abbas Sedaghat, Noushin Fahimfar, Arash Memarnejadian, M ohammad Reza
Aghasadeghi, Ali Akbar Haghdoost, Fatemeh Jahanbakhsh, Mahshid Nasehi, Ehsan Mostafavi.
Vulnerability of Homeless People in Tehran, Iran, to HIV, Tuberculosis and Viral Hepatitis.
PloS one .2014; (9): e98742
22- Nazli Jafarpour, Arash Memarnejadian, M ohammad Reza Aghasadeghi, Fatemeh Kohram,
Haniyeh Aghababa, Nima Khoramabadi, Mehdi Mahdavi. Clustered epitopes within a new polyepitopic
HIV-1 DNA vaccine shows immunogenicity in BALB/c mice. Molecular biology
reports.2014:1-8
23- Raheleh Saboohi, Bahareh Rajaei, Nahid Sepehri Rad, Mohamad Reza Razavi, M ohammad
Reza Aghasadeghi, Arfa Moshiri, Ahmad Reza Bahremand, Keivan Kave, Peiman Kave,
Mehrangiz Zangeneh, Mohammad Rahbar, Sara Khorami Sarvestani, Seyed Davar Siadat.
Molecular Detection and Association of QnrA, QnrB, QnrS and BlaCMY Resistance Genes
among Clinical Isolates of Salmonella spp. in Iran. Advances in Microbiology.2014; (4):1
24- Hoda Taghizadeh Dezfuli, Delavar Shahbazzadeh, Akram Eidi, Kamran Pooshang Bagheri,
Nafiseh Pakravan, Safie Amini, M ohammad Reza Aghasadeghi, Mehdi Mahdavi. Induction of
IFN-γ cytokine response against hepatitis B surface antigen using melittin. Gastroenterology and
Hepatology from bed to bench.2014;7 (2):108
25- Sadeghifard V, Ebrahimi A, Aghasadeghi M R, Sadat SM. The effects of 4G/5G polymorphism of PAI-1
gene in Iranian patients with schizophrenia. Medical University Journal (AMUJ) 2014; 17(83): 24-32.
26- Salva Sadat Mostafavi Dehraisi, Seyed Mehdi Sadat, Fatemeh Davari Tanha, M ohammad Reza
Aghasadeghi, Golnaz Bahramali, Mahdi Safarpour, Ahmad Ebrahimi. The effect of glutathione S-transferase
gene polymorphisms on susceptibility to uterine myoma. Tehran University Medical Journal, January 2015;
Vol. 72, No. 10: 667-673.
27- Salva Sadat Mostafavi Dehraisi, Seyed Mehdi Sadat, Fatemeh Davari Tanha, M ohammad Reza
Aghasadeghi, Mahdi Safarpour, Parinaz Abbasi Ranjbar , Ahmad Ebrahimi. Association of Glutathione S-
transferase P1 gene polymorphism and uterine leiomyoma in Iranian population. Tehran University Medical
Journal, November 2014; Vol. 72, No. 8: 508-514.
28- Akram Tabatabaee , Seyed Davar Siadat, Seyed Fazllolah Mousavi , M ohammad Reza Aghasadeghi.
Determination of antigenic determinants in the C-terminal 311 amino acids of Haps adhesion from
Nontypeable Haemophilus influenza. Medical Sciences Journal of Islamic Azad University Volume 24,
Number 2 (2014)
29- Anis Jafari, Ebrahim Shafaei, Mana Oloomi, M ohammad-Reza Aghasadeghi, Saeid Bouzari
Genotypic and Phenotypic Comparison of Enteroaggregative Escherichia coli Isolates from HIVPositive
and Non-HIV Diarrheal Samples. Current HIV research. 2013;11(8): 635-641.
30- Maryam Akhavan Tabasi, Massoud Amanlou, Seyed Davar Siadat, Zahra Nourmohammadi,
Farnoor Davachi Omoomi, Seyed Esmaeil Sadat Ebrahimi, M ohammad Reza Aghasadeghi,
Pooneh Rahimi, Sahar Pourhosseini, Bita Mehravi, Mehdi Shafiee Ardestani.Novel Molecular
Anti-Colorectalcancer Conjugate: Chlorambucil-Adipic Acid Dihydrizide-Glutamine.
Anti-Cancer Agents in Medicinal Chemistry . 2013; 13(9): 1449-1459.
31- Azam Bolhassani, Shabnam Javanzad, Tayebeh Saleh, Mehrdad Hashemi, M ohammad Reza
Aghasadeghi, Seyed Mehdi Sadat. Polymeric nanoparticles: potent vectors for vaccine delivery
targeting cancer and infectious diseases. Human vaccines & immunotherapeutics. 2013; 10(2).
11-10
32- Maryam Yazdanian, Arash Memarnejadian, Mehdi Mahdavi, Seyed Mehdi Sadat, Fatemeh
Motevali, Rouhollah Vahabpour, Hossein Khanahmad, Seyed Davar Siadat, M ohammad Reza
Aghasadeghi, Farzin Roohvand. Immunization of Mice by BCG Formulated HCV Core Protein
Elicited Higher Th1-Oriented Responses Compared to Pluronic-F127 Copolymer. Hepatitis
monthly .2013;13(10)
33- Ali S Salmani, M ohammad R Aghasadeghi, Rakhshandeh Nategh, Talat Mokhtari-Azad,
Seyed D Siadat.Methanobrevibacter smithii Archaeosomes-Entrapped mzNL4-3 Virus-Like
Particles Induce Specific T helper 1-Oriented Cellular and Humoral Responses Against HIV-1.
Current HIV research. 2013; 11(6): 491-497
34- Akram Tabatabaee, Seyed Davar Siadat, Seyed Fazllolah Moosavi, M ohammad Reza
Aghasadeghi, Arash Memarnejadian, Mohammad Hassan Pouriayevali, Neda Yavari
Overexpression and Purification of C-terminal Fragment of the Passenger Domain of Hap
Protein from Nontypeable Haemophilus influenzae in a Highly Optimized Escherichia coli
Expression System. Avicenna journal of medical biotechnology. 2013; 5(3): 176.
35- M ohammad R Aghasadeghi, Hossein Heidari, Seyed M Sadat, Shiva Irani, Safieh Amini,
Seyed D Siadat, Mohammad E Fazlhashemy, Rezvan Zabihollahi, Seyed M Atyabi, Seyed B
Momen, Mohammad S Khosraavy, Mehdi Davari, Tahmineh Darvishmohammadi, Mohammad
Doroudian, Mehdi S Ardestani. Lamivudine-PEGylated Chitosan: A Novel Effective Nanosized
Antiretroviral Agent. Current HIV research. 2013; 11(4); 309-320.
36- Massoud Amanlou, Zahra Heidari, Seyed Davar Siadat, M ohammad Reza Aghasadeghi,
Masoud Ghorbani, Seyed Esmaeil Sadat Ebrahimi, Seyed Mehdi Sadat, Mehdi Hajmohammadi,
Ali Jabbari Arabzadeh, Soheila Hekmat, Mahmood Alaei-Beirami, Alireza Azizi Saraji, Hadi
37-Fathi Moghaddam, Mohammad Shafiee Alavidjeh, Seyed Ali Delbaz, Abolfazl DashtbaniRoozbehani, Mehdi Shafiee Ardestani. Nanosized Tamoxifen-Porphyrin-Glucose [TPG]
Conjugate: Novel Selective Anti-breast-cancer Agent, Synthesis and In Vitro Evaluations.
Medicinal Chemistry. 2013; 9 (4): 526-528
38- M ohammad Reza Aghasadeghi, Minoo Mohraz, Golnaz Bahramali, Arezoo Aghakhani,
Mohammad Banifazl, Maryam Foroughi, Farrokhlagha Ahmadi, Ali Eslamifar, Seyed Mehdi
Sadat, Amitis Ramezani. Frequency and genotype of hepatitis D virus infection in patients
infected with HIV and those undergoing hemodialysis. Hepatitis monthly. 2013;13 (5)
39- Zeinab Vakili Ghartavol, Seyed Moayed Alavian, Safieh Amini, Rouhollah Vahabpour,
Golnaz Bahramali, Ehsan Mostafavi, M ohammad Reza Aghasadeghi. Prevalence of Occult
Hepatitis B Virus in Plasma and Peripheral Blood Mononuclear Cell Compartments of Patients
With Chronic Hepatitis C Infection in Tehran-Iran. Hepatitis monthly. 2013;13(5)
40- Jamshid Farmani, Farzin Roohvand, Mohammad Safari, M ohammad Reza Aghasadeghi,
Seyyed Hadi Razavi, Fatemeh Motevalli. Cell surface display of Propionibacterium acnes
linoleic acid isomerase by Pichia pastoris. Romanian Biotechnological Letters. 2013;18(3);8308
41- Z Hajimahdi, A Zarghi, R Zabihollahi, M R Aghasadeghi. Synthesis, biological evaluation,
and molecular modeling studies of new 1, 3, 4-oxadiazole-and 1, 3, 4-thiadiazole-substituted 4-
oxo-4H-pyrido [1, 2-a] pyrimidines as anti-HIV-1 agents. Medicinal Chemistry Research.2013;
22 (5): 2467-2475
42- Fatemeh Jahanbakhsh, Junko Hattori, Masakazu Matsuda, Shiro Ibe, Seyed-Hamid R
Monavari, Arash Memarnejadian, M ohammad R Aghasadeghi, Ehsan Mostafavi, Minoo
Mohraz, Hossain Jabbari, Kianoush Kamali, Hossein Keyvani, Kayhan Azadmanesh, Wataru
Sugiura. Prevalence of transmitted HIV drug resistance in Iran between 2010 and 2011. PloS
one. 2013; 8 (4): e61864
43-Hossein Heydari, Mehdi Shafiee Ardestani, Rezvan Zabihollahi, Seyed Mehdi Sadat, Shiva
Irani, Safiyeh Amini, Seyed Davar Siadat, Mohammad Sadegh Khosravi, Alireza Azizi Saraji,
Pooneh Rahimi, Soheila Hekmat, M ohammad Reza Aghasadeghi. Synthesis and
physicochemical evaluation of nanosized Lamivudine loaded PEGylated Chitosan. Arak Medical
University Journa.2013;16(6)
44-Sogol Asaadi Dalaei, Rezvan Zabihollahi, Seyed Mahdi Sadat, Seyed Davar Siadat, Nour
Amirmozafari, Azar Farhang Esfahani, Sohila Hekmat, M ohammad Reza Aghasadeghi
Inhibitory Effects of Novel 3-Hydroxy-4-Pyridinones with Iron Chelating Activity against
Production of HIV Virions. Journal of Mazandaran University of Medical Sciences
(JMUMS).2013;(97)
45-Mohammad Hasan Pouriayevali, Mehdi Zavvar, M ohammad Reza Aghasadeghi, Sayed
Mehdi Sadat, Alireza Azizi-Saraji, Fozieh Javadi, Javid Sadraraei, Ehsan Mostafavi, Fatemeh
Motevalli, Pooneh Rahimi. A study on the prevalence of rotavirus infection among the HIVpositive
patients with gastroenteritis.Authors. Feyz Journals of Kashan University of Medical
Sciences.2013;17(3)
46- Malihe Keramati, Farzin Roohvand, Mohammad Mehdi Aslani, Shohreh Khatami,
M ohammadReza Aghasadeghi, Mehdi Sadat, Arash Memarnejadian, Fatemeh Motevalli
Screening, Cloning and Expression of Active Streptokinase from an Iranian Isolate of S. Iranian
journal of basic medical sciences equisimilis Group C in E. coli.2013;16 (4):620.
47- Z Hajimahdi, R Zabihollahi, M R Aghasadeghi, A Zarghi.Design, Synthesis and Docking
Studies of New 4-hydroxyquinoline-3-carbohydrazide Derivatives as Anti-HIV-1 Agents. Drug
research.2013; 3(4):192-197.
48- Rezvan Zabihollahi, Afshin Fassihi, M ohamad Reza Aghasadeghi, Hamid Reza Memarian,
Mohammad Soleimani, Keivan Majidzadeh-A. Inhibitory effect and structure–activity
relationship of some Biginelli-type pyrimidines against HSV-1. Medicinal Chemistry
Research.2013; 22 (3): 1270-1276
49- Fatemeh Salem, Soheila Hekmat, M ohammad Reza Aghasadeghi, Foozieh Javadi, Hossein
Gholami, Ehsan Mostafavi.Prevalence and Risk Factors of Hepatitis B Virus Genotype D
Amongst Inmates in Alborz Province, Iran: A Cross-Sectional Survey. Jundishapur Journal of
Microbiology. 2013;6 (6)
50- Seyed Ali Delbaz, Seyed Davar Siadat, M ohammad Reza Aghasadeghi, Mohamad Piryaie,
Shahin Najar Peerayeh, Seyed Fazlollah Mousavi, Arfa Moshiri, Seyed Mehdi Sadat, Mehrangiz
Zangeneh, Mehdi Nejati, Nafiseh Kashanizadeh, Saied Bouzari. Biological and Immunological
Evaluation of Neisseria meningitidisSerogroup A Outer Membrane Vesicle as Vaccine
Candidates. Jundishapur Journal of Microbiology.2013; 6(4)
51- AG Khosroshahi, M Amanlou, O Sabzevari, FJ Daha, M R Aghasadeghi, M Ghorbani, MS
Ardestani, MS Alavidjeh, SM Sadat, MH Pouriayevali, L Mousavi, SES Ebrahimi. A
comparative study of two novel nanosized radiolabeled analogues of methionine for SPECT
tumor imaging. Current medicinal chemistry. 2013; 20 (1): 123-133.
52-Shaghayegh Yazdani-Neyshabouri, M ohammad Reza Aghasadeghi, Ali Jahanian
Najafabadi, Saeid Bouzari, Arash Arashkia, Seyed Mehdi Sadat, Seyed Davar Siadat, ZohreAzita Sadigh, Soheila Hekmat & Mohammad Hasan Pouriaye Vali .Expression of recombinant
HCV core, E1 and E2 proteins by the baculovirus expression vector system African Journal of
Microbiology Research 2012 .Vol.6 (2)
53-Safieh Amini, Seyed Moayed Alavian, Ehsan Mostafavi, Rouhollah Vahabpuor, Golnaz
Bahramali, M ohammad Reza Aghasadeghi & Arash Arashkia. Presence of plus-strand HCV
RNA in serum and PBMC as an indicator for relapse and resistance to IFN therapy in patients
infected by HCV. Future Virol. 2012 .7(3):323-330
54- R. Saboohi,S.D Siadat, M ohammad Reza Aghasadeghi M.R Razavi, B. Rajaei, N.S Rad,
A. Moshiri, S.F Mousavi, S. Javadian, K. Kave, A. Dashtbani, S.M Sadat and S,G Nejad.
Molecular Detection of qnrA, qnr B and qnr S Resistance Genes among Samonella sp.in Iran.
Current research of bactriology .2012
55-Parasurman S, Revendran R, M ohammad Reza Aghasadeghi, Mehdi Shafiee Ardestani,
Ramesh A, Dhanapathi H. Normal and tumoric animal model kinetic distribution pattern of the
Cleistanthin A and B using Magnetic Resonance Imagin. Pharmacognosy magazine
(accepted)2012
56- M ohammad Reza Aghasadeghi , Seyed Davar Siadat, Mehdi Shafiee Ardestani Ali Jabbari
Arabzadeh, Mitra Elmi and Hadi Fathi Moghaddam. Selective Cyclooxygenase-2 Inhibitor
Compound 11b Improves Haloperidol Induced Catatonia by Enhancing the Striatum
Dopaminergic Neurotransmission. Iranian Journal of Pharmaceutical Research .
2012.11(1):343-349
57-Rezvan Zabihollahi, Seyed Mehdi Sadat, Rouhollah Vahabpour, Mansoor Salehi, Keyhan
Azad manesh,Seyed davar Siadat,Ali Reza Azizi Saraji, Seyed Bahman Momen, M ohammad
reza Aghasadeghi .Introducing a frame shift mutation to the pol sequence of HIV-1 provirus
and evaluation of the mutated virions (RINNL4-3) .Journal of Molecular Biology(accepted)
2012
58-F. Baghbani-arani, F. Roohvand, M .R. Aghasadeghi, A.Eidi, S.Amini, F. Motevalli, S.M.
Sadat, A. Memarnejadian, G. Khalili. Expression and Characterization of E.coli-Derived
Hepatitis C Virus ARFP/F Protein. Journal of Molecular Biology.2012. 46 (2):226-234
59- Mahdi Habibi Anbouhi, Mohsen Abolhasani, Saeid Bouzari, Hossein Khanahmad,
M ohammad Reza Aghasadeghi, Armin Madadkar- Sobhani, Amir Amanzadeh, Mahdi Behdani
and Mohammad Ali Shokrgozar. Immunological evaluation of predicted linear B-cell epitopes of
human CD20 antigen. Biotechnology and Applied Biochemistry. 2012. DOI: 10.1002/bab.1012
60- Rouhollah Vahabpour , Seyed Mehdi Sadat , Rezvan Zabihollahi , Amrollah Ahmadi ,
Hossein Keivani , Safieh Amini , Seyed Davar Siadat , Mohammad Reza Aghasadeghi In Vitro
Inhibitory Effects of the Herbal-Marine Compound HESA-A Against Replication of Human
Immunodeficiency Virus-1. 2012. Jundishapur J Microbiol. 2012;5(1):315-319
61- R.zabihollahi, R vahabpour,C. Hartoonian, B.Sedaghati, S.M Sadat, MSoleymani, M.
Ranjbar, A. Fassihi, M .R Aghasadeghi, H.F Memarnejadian, M Salehi. Evaluation of the in
vitro antiretroviral potential of some Biginelli-type pyrimidines. Acta Virologica 2012. 56(1):
11-18
62- Ali Salehzadeh, Hamidh Ofoghi, Farzin Roohvand, M ohammad Reza Aghasadeghi,
Kazem Parivar. Human Calcitonin (hCT) Gene Expression and Secretion by Pchia pastoris.
Romanian Biotechnological Letters. 2012. Vol.17,No.1.
63- Sabet R, Behjati M, Vahabpour R, Memarnejadian A, Rostami M, Fassihi A, Aghasadeghi
M R, Saghaie L, Miri R. Iron chelation afforded cardioprotection against H(2)O(2)-induced
H9C2 cell injury: Application of novel 3-hydroxy pyridine-4-one derivatives. 2012. Int J Cardiol.
doi:10.1016/j.ijcard.2011.11.067.
64- M ohammad Reza Aghsadeghi, Golnaz Bahramali, Seyed Davar Siadat, Ahmad Farahani
far, Minoo Mohraz, Seyed Davar Siadat, Ehsan Mostafavi, Arash Memarnejadian, Mehdi
Shafiee Ardestani, Rouhollah Vahabpour, Alireza Azizi Saraji, and Seyed Ali Delbaz. Detection
of Hepatitis B Virus Variants in HBV Monoinfected and HBV/HIV Coinfected Iranian Patients
Under Lamivudine Treatment. Current HIV Research 2011. 9,263-269.
65-Seyed Davar Syadat, Saied Reza Nadaf, Mehrangiz Zangeneh, Arf Moshiri, Seyed Mehdi
Sadat, Mehdi Shafiee Ardestani, Mohammad Hasan Pouriayevali, Safieh Amini And
M ohammad Reza Aghasadeghi. Outer memberane vesicle of Neisseria meningitides serogroup
B as an adjuant in immunization of rabbit against Neisseria meningitides serogroup A. African
Journal of Microbiology Research. 2011. 5(19):3090-95.
66-Shiva Irani,Seyed Mohammad Atyabi, Houri Mivenchi, Seyed Davar Siadat, M ohammad
Reza Aghasadeghi, Ali Farhangi. Solvent effects on structural and thermochemical properties of
p53 tumor-suppressor gene: a molecular modeling approach in drug design. International
Journal of Nanomedicine 2011. 6:2063-69.
67- Bahareh Rajaei, Seyed Davar Siadat, Mohamad Reza Razavi M ohammad Reza
Aghasadegh, Nahid Sepehri Rad, Farzad Badmasti, Somieh Khanjani Jafroodi, Taraneh Rajaei,
Arfa Moshiri and Saifuddin Javadian. Expanding drug resistance through intergron acquisition in
Salmonella spp. Isolates obtained in Iran. African Journal of Microbiology Research 2011.
5(16):2249-53
68- Arash Pourgholaminejad, Arezoo Jamali,Morteza Samadi- Foroushani, Afshin Amari, Reza
Mirzaei, Bita Ansaripour, Nemat Khansari, M ohammad Reza Aghasadeghi, Babak Baban,
Jamshid Hadjati. Reduced efficacy of multiple doses of CpG-matured dendritic cell tumor
vaccine in an experimental model . Cellular Immunology. 2011.271:360-364
69- Ali salehzadeh. Hamideh ofoghi, Farzin roohvand, M ohammad Reza Aghasadeghi, Kazem
Parivar . Intracellular expression of human calcitonin (hCT) gene in the Methylotrophic Yeast
Pichia pastoris. African Journal of Microbiology Research. 2011. 10(59):12721-26
70-Reza Arabi, Farzin Roohvand (Corr. Author), Daryoush Norouzian, Soroush Sardari,
M ohammad reza Aghasadeghi, Hosein Khanahmad, Arash Memarnejadian, Fatemeh
Motevalli. A comparative study on the activity and antigenicity of truncated and full-length
forms of streptokinase. Polish Journal of Microbiology. 2011. Vol. 60,No 3,243-251
71-Massoud Amanlou, Seyed Davar Siadat, Dariuosh Norouzian.Seyed Esmaeel Sadat Ebrahimi,
M ohammad reza Aghsadeghi,Masoud Ghorbani, Mohammad Shafiee Alavidjeh, Davoud
Nouri Inanlou, Ali Jabbari Arabzadeh and Mehdi Shafiee Ardestani. Magnetic Resonance
Contrast Media Sensing In Vivo Molecular Imaging Agents: An Overview. Current
Radiopharmaceuticals .2011. 4,31-43.
72-Reza Ahangari Cohan, Armin Madadkar- Sobhani- Hossein Khanahmad, Farzin Roohvand,
M ohammad Reza Aghasadeghi, Mohammad Hossein Hedayati, Zahra Barghi, Mehdi Shafiee
Ardestani, Davoud Nouri Inanlou, Driush Norouzian. Design, modeling, expression, and
chemoselective PEGylation of a new nanosize cysteine analog of erythropoietin. Jornal of
Nanomedicine. 2011. 6:1217-1227
73-Seyed Davar Siadat, M ohammad Reza Aghasadeghi, Maryam Kheirandish. Immunological
Aspect of Meningococcal disease: An overview in Host-Bacteria Interaction. International
Journal of Molecular and Clinical Microbiology. 2011. 1(1):1-8
74-Seyed Mehdi Sadat, Rezvan Zabihollahi, M ohammad Reza Aghsadeghi, Rouhollah
Vahabpour, Seyed Davar Siadat, Arash Memarnejadian, Keyhan Azadmanesh, Kazem Parivar.
Application of SCR Priming VLP Boosting as a Novel Vaccination Strategy Against HIV-1.
Curr HIV Res. 2011. 9(3):140-7.
75- Mohammad Reza Aghasadeghi, Ali Sharifat Salmani, Seyed Mehdi Sadat, Foozieh Javadi,
Arash Memarnejadian, Rouhollah Vahabpour, Rezvan Zabihollahi, Arfa Moshiri and Seyed
Davar Siadat. Application of Outer Membrane Vesical of Neisseria meningitides Serogroup B as
a New Adjuvant to Induce Strongly Th1- Oriented Responses Againt HIV-1. Current HIV
Research,2011,9,630-635.
76-Massoud Amanlou, Seyed Davar siadat, Dariuosh Noroozian, M ohammad Reza
Aghsadeghi, Hadi Fathi- Moghadam, Mohammad Piryaei, Mehdi Shafiee Ardestani. Effect of
Dexamethasone Striatal Neurotransmission in the Rats Subjected to Parkinson's Disease Animal
model. Iranian Journal of Basic Medical Sciences. 2011. 14,2,161-169
77-Seyed Davar siadat, M ohammad Reza Aghasadeghi, Sahar Krami, seyed Mehdi sadat, Arfa
Moshiri. Biological and immunological characteristics of Brucella abortus S99 major outer
membrane proteins. Jundishapur Journal of Microbiology. 2011; 4 (1):29-36
78- Massoud Amanlou, Seyed Davar siadat, Seyed Esmaeil sadat Ebrahimi, Abass Alavi,
M ohammad Reza Aghsadeghi, Mehdi Shafiee Ardestani, Saeed Shanehsaz, Masoud Ghorbani,
Bita Mehravi, Mohammad Shafiee Alavidjeh, Ali jabbbari- Arabzadeh, Mehdi Abassi. Gd3+DTPA-DG:novel nanosized dual anticancer and molecular imagin agent. Internatinal Journal of
Nanomedicine. 2011. 6-P 747-763.
79-R.zabihollahi, S.M Sadat, R. Vahabpour, M .R Aghasadeghi, A, Memarnejadian,
T,Ghazanfari, M salehi, A. Rezaeee, K, Azadmanesh. Development of single-cycle replicable
human immunodeficiency virus 1 mutants. Acta Virologica 2011. 55: 15-22
80- Pouriayevali, M.H., Memarnejadian, A., Sadat, S.M., Zavvar, M., Siadat, S.D., Hartoonian, C.,
Aghasadeghi, M.R. Designing and construction of bicistronic plasmid pIRES-Igk/mIL18/Fc:
potential implications for vaccine investigations. Modarres Journal of Medical Sciences
(Pathobiology) 2011, 14 (2): 13-23.
81- Jamshid Farmani, Mohammad Safari, Farzin Roohvand, Seyed Hadi Razavi, M ohammad
Reza Aghasadeghi, Hassan Noorbazagan. Conjugated Linoleic acid-producing enzymes: A
bioinformatic study. European Journal of LIPID 2010. 112:1088-1100.
82- Nima Rezaei, Seyed Davar Siadat, Asghar Aghamohammadi, Mostafa Moin, Zahra Pourpak,
Dariush Norouzian, Jalal Izadi Mobarakeh, M ohammad Reza Aghasadeghi, Mehdi Nejati,
Robert C.Read. Serum Bactericidal Antibody Response 1Year after Meningococcal
polysaccharide Vaccination of Patients with Common Variable Immunodeficiency Clinical and
Vaccine Immunology. 2010. (17): 524-528.
83- Morteza Samadi- Foroshani, Rouhollah Vahabpoor, Arash Memarnejadian, Afshin Namdar,
Masoumeh Khamsabadi, Seyed Mehdi Sadat,Hossein Asgarian- Omran, Keyhan Azadmanesh,
Parviz Kohaei, M ohammad Reza Aghsadeghi, Jamshid Hadjati. Immune responses regulation
following antitumor dendritic cell-based prophylactic,concurrent, and therapeutic vaccination.
Med Oncol. 2010. 28(1):660-666.
84-Arash Arashkia, Farzin roohvand, Arash Memarnejadian, M ohammad Reza Aghasadeghi,
Sima Rafati. Construction of HCV-polytope vaccine candidates harbouring immune- enhancer
sequences and primary evalution of their immunogenicity in BALB/c mice. Virus Genes. 2010.
40: 44-52.
85-Arabi, R., Roohvand, F., Norouzian, D., Aghasadeghi, M.R., Memarnejadian, A., Khanahmad,
H., Sadat, S.M., Motevalli, F. Cloning and expression of truncated and intact streptokinase molecules
in E.coli and evaluation of their biological activities. Journal of Agricultural Biotechnology 2010, 2
(1): 55-67.
86- Arashkia, A., Roohvand, F., Memarnejadian, A., Alizadeh, S., Motavali, F., Aghasadeghi, M.R.
Immunoinformatics modeling, construction of DNA plasmids, inserted with hepatitis C virus CTL
epitopes and their preliminary immunological analysis. Iranian Medical Microbiology 2010, 4 (2):
34-44.
87-Monzavi, N., Aghasadeghi, M .R., Arabi, R., Memarnejadian, A., Sadat, S.M., Khanahmad, H.,
Ebrahimi, M., Roohvand, F. Design, cloning, expression and evaluation of cysteine-substitutes of
intact and truncated molecules of streptokinase. Physiology and Pharmacology 2010, 14 (1): 56-65.
88-Memarnejadian, A., Roohvand, F., Motevalli, F., Aghasadeghi, M .R. Experimental polytope
DNA vaccine containing HBsAg gene for the induction of protective immunity against hepatitis C.
Feiz, Journal of Kashan University of Medical Sciences 2009, 13 (3): 161-73.
89-Memarnejadian, A., Roohvand, F., Arashkia, A., Berjisian, F., Aghasadeghi, M .R.
Designing, construction and immunogenic evaluation of polytope DNA constructs by the
application of hepatitis C virus immunodominant epitopes in BALB/c mice. Yakhteh Medical
Journal 2009, 11 (2): 122-33.
90-Ali Sharifat Salmani, Seyed davar Siadet,Mohammad Reza Fllahian, Hojat Ahmadi Dariush
Norouzian,Prichehr Yaghmai, M ohammad Reza Aghasadeghi, jalal Izadi Mobarake, Seyed
Mehdi Sadat, Mehrangiz Zangeneh,Maryam Kheirandish. Serological Evaluation ob Brucella
abortus S99 Lipopolysaccharide Extracted by an Optimized Method. American Journal of
Infection Diseases. 2009. 5 (1): 11-16.
91-Maryam Kheirandish, Seyed davar Siadet, Dariush Norouzian, Mohammad Reza Razavi,
M ohammad Reza Aghasadeghi, Nima Rezaei, Ali Farazmand, jalal Izadi Mobarake,
Mehrangiz Zangeneh, Arfa Moshiri, Seyed Mehdi Sadat, Ali Sharifat Salmani. Measurment of
opsonophagocytic activity of antibodies specific to Neisseria meningitidis serogroup A capsular
polysaccharide- serogroup B outer membrane vesicle conjugate in animal model. Annals of
Microbiology. 2009. 59 (4)-801-806
92-Ali Sharifat Salmani, Seyed davar Siadet, Dariush Norouzian, jalal Izadi Mobarake,
Mehrangiz Zangeneh, M ohammad Reza Aghasadeghi, Mehdi Nejati, Arfa Moshiri, Seyed
Mehdi Sadat. Outer member vesical of Neisseria meningitidis serogroup B as an adjuvant to
induce specific antibody response against the lipopolysaccharide of Brucella abortus S99. Annals
of Microbiology 2009. 59 (1) 145-149.
93-Monzavi, N., Arabi, R., Aghasadeghi, M.R., Memarnejadian, A., Roohvand, F. Streptokinase:
The drug of choice for thrombolytic therapy in developing countries. Laboratory Diagnosis
(ISSN 1561-6363, www.tashkhis.com) 2009, 59: 61-68.
94-Golnaz Bahramali, Majid Sadeghizadeh, Samad Amini-Bavil-Olyaee , Seyed-Moayed
Alavian, Abbas Behzad-Behbahani, Ahmad Adeli, M ohammad Reza Aghasadeghi, Safieh
Amini, Fereidoun Mahboudi. Clinical, virological and phylogenetic features of hepatitis B
infection in Iranian patients. World journal of gasteroenterology-2008. 14(35):5448-5453.
95-Farzin Roohvand , M ohammad-Reza Aghasadeghi, Seyed Mehdi Sadat, Agata Budkowska
and Ali-Reza Khabiri. HCV core protein immunization with Montanide/CpG elicits strong
Th1/Th2 and long-lived CTL responses. BBRC, 2007. 354:641-649.
96-Aghasadeghi M .R., Sadat S.M., Khabiri A.R., Amini S., Budkowska A,Bahramali G.,
Naddaf S.R. and Roohvand F. Evaluation of a native preparation of HCV core protein (2-122)
for potential applications in immunization, diagnosis and mAb production. Iranian journal of
public health .2006. 35(1):1-10.
I nternational & National M eetings:
1- Vida Sadeghifard, Seyed Mehdi Sadat, Ahmad Ebrahimi, M ohammad Reza Aghasadeghi,
Abas Gharagouzloo, Elham Sadeghi, Foozieh Javadi. STUDYING RELATIONSHIP BETWEEN
SCHIZOPHRENIA AND PAI-1 4G/5G POLYMORPHISM IN IRANIAN PATIENTS. Schizophrenia
Research.2014; 13(S361). Elsevier
2- Zoheir Heshmatipour, Ramezan Ali Khavarinejad, Seyed Davar Siadat, Anita Khanafari,
Mohamad Reza Aghasadeghi.An Investigation in to Distribution Pattern and Molecular
Evaluation of Facultative Anaerobic Thermophilic Bacteria in Hot Spring Sehezar IRAN
2012/6/25 .The 13th Iranian & The Second International Congress of Microbiology
3- Yazdani Neyshabouri S, Arashkia A, Sadat S M, Siadat SD, Sadigh ZA, Hekmat S, Pouriaye
vali MH, Azizi Saraji A, Aghasadeghi M R, Designinig and construction of recombinant insect
vector for the expression of Hepatitis C complete structural genes. First International and 12 th
Iranian Congress of Microbiology Kermanshah, Iran Poster Presentation. 23-26 May 2011.
4-Sadat S M, Zabihollahi R, Aghasadeghi M R, Vahabpour R, Javadi F, Siadat SD, Parivar K,
Azadmanesh K, Hekmat S, Motevalli F, VLP immunization with Montanide/ CpG elicite strong
Th1/Th2 responses against HIV. First International and 12 th Iranian Congress of Microbiology
Kermanshah, Iran Poster Presentation. 23-26 May 2011.
5-Yazdani Neyshabouri SH, Jahanian Najafabadi A, Bouzari S, Arashkia A, Sadat S.M, Amini S,
Azita Sadigh Z, Hekmat S. Aghasadeghi M .R. Costruction of recombinant bacmid for the
expression of Core, E1,E2, genes of hepatitis C virus. The 5th Iranian Congress of Clinical
Microbiology. Shiraz- Iran Poster Presentation. 8-10 Nov.2011. Poster Presentation
6-Moshiri A, Aghasadeghi M .R, Farajollahi M. Pouriaievali MH, Sadat SM, Rajaei B,
Mokhtarpour M. Designing and Construction of Bicistronic Plasmid Capable of Simultaneous
Expression of Hepatitis C virus NS3 Protein and IL18. The 5th Iranian Congress of Clinical
Microbiology. 8-10 Nov.2011.
7-Zabihollahi R. Aghasadeghi M .R , Sadat M, Fassihi A. HIV and HSV inhibitory activity of
some 3-Hydroxypyridin-4-ones derivates with iron chelation activity. The 5th Iranian Congress
of Clinical Microbiology. Shiraz- Iran. 8-10 Nov.2011 Poster Presentation
8-Zavar M, Sadat SM, Aghasadeghi MR, Pouriayevali, Baradaran L, Javadi F, Amini S, Hekmat
S. Detection of Adenovirus and Cryptosporidium infection among Iranian HIV positiveassosiated
Diarrhea. The 5th Iranian Congress of Clinical Microbiology. Shiraz- Iran. 8-10
Nov.2011 Poster Presentation
9-Zabihollahi R. Motevaseli E Sadat S,M, Aghasadeghi M .R , Modarresi M.H. Evaluating the
in vitro inhibitory activity of some lactobacillus strains against HIV and HSV replication. The 5th
Iranian Congress of Clinical Microbiology. Shiraz- Iran. 8-10 Nov.2011. Poster Presentation
10-Zabihollahi R. Pooshang Bagheri K. Sadat M. Pouriayevali, M.H. Azizi Saranji A.R.
Ghasemi- Dehkordi P. Aghasadeghi M .R.Shahbazzadeh D. A natural component of the
scorpion Hemiscorpius Lepturus venom inhibits the in vitro replication of HIV. The 5th Iranian
Congress of Clinical Microbiology. Shiraz- Iran. 8-10 Nov.2011 Poster Presentation
11-Soheila Hekmat, Mahdieh Soezi, Arash Memarnejadian, M ohammad Reza Aghasadegh,
Seyed Mehdi Sadat, Seyed Davar Siadat, Poonneh Rahimi. Designing and construction of
recombinant pIPI- GFP plasmid expressing HIV-1 virions as a novel system for HIV-1
replication assay. MicroBiotec 2011 Congress- Braga,Portugal. 1-3 Dec 2011. Poster
Presentation
12-M ohammadReza Aghasadeghi, Shaghayegh Yazdani Najafabadi, Ali Jahanian- Najafabadi,
Saeid Bouzari, Arash Arashkia, Seyed Mehdi Sadat, Seyed Davar Siadat, Safieh Amini, Zohre
Azita Sadigh, Soheila Hekmat, Poone Rahimi. Expresssion of recombinant Core, E1,E2-HCV
proteins in Sf9 insect cells. MicroBiotec 2011 Congress- Braga,Portugal. 1-3 Dec 2011 Poster
Presentation.
13-F.Baghbani.F.Roohvanv, M .R Aghasadeghi, S.Amini,F. Motevalli, S.M Sadat, A
Memarnejadian. PO59 E.Coli-generated recombinant HCV core+1 (ARFP) Protentially valuable
diagnostic and immunotherapeutic tool .14th Annual Meeting of the European Society of Clinical
Virology (ESCV) .Madrid. 21-24 sep 2011. Poster Presentation
14-S.M Sadat, M .R Aghasadeghi, R.Vahabpour, R. Zabiholahi, F. Javadi, S.D Siadat, K.
Azadmanesh, K. Parivar, A, Delbaz, M,Davari. Prime- double boost SCR/VLP: New formulation
as a candidate vaccine against HIV-1. International Student Congress of (bio) Medical Student, ,
(ISCOMS2011). Croningen – the Netherland. 7-10 th June 2011 Poster Presentation
15-F. Javadi M .R Aghasadeghi, S.D Siadat S.M Sadat, R.Vahabpour, R. Zabiholahi, Outer
membrane vesical of Neisseria meningitides serogroup B as a new adjuvant to inuce strong
immune responses against HIV-1 International Student Congress of (bio) Medical Student, ,
(ISCOMS2011) Netherland. 7-10 th June 2011 Poster Presentation
16-S.M. Sadat, R. Zabihollahi,R. Vahabpoor, K. Azadmanesh,F. Javadi, S.D Siadat,
A.Memarnejadian, K.Parivar, H. KhanAhmad Shahreza, R.Arabi Mianroodi, S. Hekmat, M .R
Aghasadeghi. Designing and biological evaluation of single- cycle replicable HIV-1 system as a
potential vaccine strategy. 20 th ECCMID. Vienna Austria 10-13 April 2011 Poster Presentation
17-M .R Aghasadeghi, A. farahani, G. bahramali,S.M. Sadat, A. Memarnejadian. S.D Siadat,
M. Mohraz,M. Foroughi, F. Javadi,F. Roohvand,R. Vahabpoor,M.R Pouriayevali. Prevalence of
HBV Lamivudine- Resistance Mutations in a cohort of Iranian HBV- infected patient with and
without HIV co-infection. 20 th ECCMID. Vienna Austria 10-13 April 2011 Poster Presentation
18-S.D. Siadat, M .R Aghasadeghi, M. Mohammadi, M.Kheirandish, D, norouzian, J.Isadi
Mobarakeh, M. Rzavi,M.Zangeneh, S.M Sadat, A. SHarifat salmani, A. Moshiri. Biological and
immunological characteristic of new lipopolysaccharid-based conjugate vaccine for brucllosis.
20 th ECCMID. Vienna Austria 10-13 April 2011 Poster Presentation
19-M .R. Aghasadeghi, S.D Siadat, B.Rajaei, F. Badmasti, N.Sepehri Rad, R.Sabohi,
S.Javadian, M.R Razavi,S.Najar Peerayeh, S.M Zahraee, R.A Khavari-Nejad, S.M Sadat, A.
Moshiri, A.Rahimi. Molecular detection of class1 integron associated antimicrobial gen cassettes
in multidrug-resistant Salmonella serovars isolated in Iran. 21th European Cngress of Clinical
Microbiology and Infectious Diseases & 27th Internatinal Congress of Chemotherapy
(ECCMID). Milan,Italy. 7-10 May 2011. Poster Presentation
20-S.D Siadat, H. Shirdast, S. Soleymanian, M.Mohammadi, P.Zulfigar M.Muraduv, M .R.
Aghasadeghi, , S. Javadian, S.F Mosavi, M. Kheirandish, M.Zangeneh, S.M Sadat, A.Moshiri,
R. Haji Abedneini, Evaluation of Cytokine profile following immunization with Brucella abortus
S99 Lipopolysaccharide- Neisseria meningtidis serogroup B outer memberane vesicle conjugate
as a new brucellosis vaccine candidate. 21th European Cngress of Clinical Microbiology and
Infectious Diseases & 27th Internatinal Congress of Chemotherapy (ECCMID) . Milan,Italy. 710 May 2011. Poster Presentation.
21-M.S Pouriayevali, S. M Sadat, M .R Aghasadeghi, M. Zavar, F Javadi, S.D Siadat, A.R
Saraji,A Delbaz, R Vahabpoor,J Sadraei, R Edalat. Prevalence of rotavirus infection among
Iranian HIV- infected patients with gastroenteritis. 14th Tabriz International Medical Sciences
Congress Abstract Book (TIMSC 2011). Tabriz, Iran. 12-14 May 2011. Poster Presentation
22-M. Zavar, S. M Sadat , M .R Aghasadeghi M.S Pouriayevali, , F Javadi, S.D Siadat, S
Amini, S Hekmat, F Motevalli, J Sadraei. Another case for gastroenteritis episodes among
Iranian HIV infected patients. 14th Tabriz International Medical Sciences Congress Abstract
Book (TIMSC 2011). Tabriz, Iran. 12-14 May 2011. Poster Presentation
23-Rajaei B, Siadat S.D,Razavi M.R, Aghasadeghi MR, Sepehri Rad .R, Sabouhi R. Incidence of
Class 1 Intergrous in clinical Isolates of Salmonella.spp. 4th Iranian Congress of Clinical
Microbiology. Isfahan- Iran. 9-11 Novamber 2010 Poster Presentation
24-Zavar M, Aghasadeghi M R, Pouriaye vali MH, Sadat SM, Sadraei J, Siadat S. D et al.
Molecular detection of Enteric AAdenovirus prevalence among Iranian HIV infected patients
using Nested PCR metho. 4th Iranian Congress of Clinical Microbiology. Isfahan- Iran. 9-11
Novamber 2010 Poster Presentation
25-Sima Velashjerdi Farahani, M ohammadreza Aghasadeghi and Mehdi Mahdavi. Cellular
immune characterization against HIV-1 p24-Nef fusion peptide using Naloxone as adjuvant. The
19th Iranian Congress on Infectious disease and tropical medicin. Tehran, Iran 25-29 Des 2010.
Oral
26-Bahare Rajaei,Dr.Siadat, DR. AghasadeghiM .R, Dr. Razavi M.R, Sepehri RadN, Sabouhi R.
Incidance of Class 2 Integron in Clinical Isolates of Multidrug Resistant Salmonella. spp. 16 th
National and 4 th Internatinal Conference of Biology. Ferdowsi University of Mashhad –
Mashhad- Iran. 14-16 September 2010 Poster Presentation
27-N. Sepehri Rad, Dr. Razavi M.R, Dr.Siadat, DR., AghasadeghiM .R, Bahare Rajaei, Sabouhi
R. et all. Molecular investigation of par C mutation in QRDR in clinical isolates of salmonella
with resistance to nalidixic acid and reduced susceptibility to ciprofloxacin. 16 th National and 4
th Internatinal Conference of Biology. Ferdowsi University of Mashhad – Mashhad- Iran. 14-16
September 2010 Poster Presentation
28-Seyed Ata Sadat Shandiz, Maryam Yazdanian, M ohammad Reza Aghasadeghi, Hossein
Khanahmad, et all. Construction of recombinant BCG-HCV polytope candidate vaccine. 11th
Iranian Microbiology Congress & 1st East Mediterranean Microbiology Congress. Gillan- Iran
.May 2010 Poster Presentation
29-m. Samadi, R Vahabpoor, M. Khamisabadi, A. Namdar, H. Asgharian, A. Amini, K.
Azadmanesh, A. Memarnehadian, M Sadat, M . Aghasadeghi, j.Hajati. Evaluation of regulatory
responses after vaccination with activated dendritic cell vaccine in mice. 14 th International
Congress of Immunology Japan-2010 .Poster Presentation
30-N. Sepehri Rad, Dr. Razavi M.R, Dr.Siadat, DR., AghasadeghiM .R, Bahare Rajaei, Sabouhi
R. et all. Molecular investigation of par C mutation in QRDR in clinical isolates of salmonella
with resistance to nalidixic acid and reduced susceptibility to ciprofloxacin. 4th Iranian Congress
of Clinical Microbiology. Isfahan- Iran. 9-11 Novamber 2010 Poster Presentation
31-Farzin Roohvand, Fatemeh Motevali, Mohammadhossein, Hassan Noorbazargan, Arash
Memarnejadian, atieh hashemi, M ohammad Reza Aghasadeghi. Expression studies of native
and truncated HCV core proteins in mammalian cells. 11th Iranian Microbiology Congress & 1st
East Mediterranean Microbiology Congress. Gillan- Iran. May 2010 Poster Presentation
32-Sima Velashjerdi Farahani, M ohammad Reza Aghasadeghi, Zahra Shahosseini,Mahdieh
Motamedi Rad and Mehdi Mahdavi. Enhaceement of cellular immune responses against HIV-1
p24-Nef fusion peptide in combination of Naloxone as adjuvant. The 4th Annual Iranian Seminar
on HIV/AIDS Tehran- Iran. 29-30 Nov 2010. Poster Presentation
33-Negin Iranshahi, Reza Ranjbar, Seyed Davar Siadat, Mehdi Nejati, Naser Harzandi, Dariush
Norouzian, Bahman Tabaraiee, M ohammad Reza Aghasadeghi,et al .Evaluation of Nalidixic
Acid Susceptibility Testing for Screening of Clinical of Salmonella with Decreased
Susceptibility to Ciprofloxacin. The 3 rd Eurasia Congress of Infectious Diseases (EACID).
Baku, Azerbaijan .1-4 Oct. 2009. Poster Presentation
34- Mehdi Nejati Moheimani, Negin Iranshahi, Bahman Tabaraie, Seyed Davar Siadat, R.
Ranjbar, Daryoush Norouzian, N. Harzandi, M ohammad Reza Aghsadegh et all .Antibiotic
Susceptibility Pattern of Salmonella Sero Var Isolated from Different of Iran. The 3 rd Eurasia
Congress of Infectious Diseases (EACID). Baku, Azerbaijan .1-4 Oct. 2009. Poster Presentation.
35-Ahmad Farahani Far, M ohammad Reza Aghasadeghi, Golnaz Bahramali, Seyed Mehdi
Sadat, Seyed Davar Siadat, Foozieh Javadi, et al. HBV Genotypes and Subtypes in Iranian HBV
Infected Patients with and without HIV Infection. The 3 rd Eurasia Congress of Infectious
Diseases (EACID). Baku, Azerbaijan .1-4 Oct. 2009. Poster Presentation.
36-Arfa Moshiri, Seyed Davar Siadat, Alireza Kordafshari, M ohammad Reza Aghasadeghi,
Dariush Norouzian, Seyed Mohammad Atyabi, Fatemeh Maleki .Role of Polysaccharide
Activators in Designing Glycoconjugate Vaccines. The 3 rd Eurasia Congress of Infectious
Diseases (EACID). Baku, Azerbaijan .1-4 Oct. 2009. Poster Presentation.
37-Hoda Shirdast, Seyed Davar Siadat, Dariush Norouzian, Mohammad Reza Aghasadeghi, Ali
Sharifat, Mehdi Nejati, et al. Evaluation of IFN-y and IL-4 response against Brucella abortus S99
lipopolysaccharide-Neisseria meningitidis serogroup B complex in animal model. The 3 rd
Eurasia Congress of Infectious Diseases (EACID). Baku, Azerbaijan. 1-4 Oct. 2009. Poster
Presentation.
38-Rahman Ghaffarzadegan Rabati, M ohammad Reza Aghasadeghi, Seyed Davar Siadat, Reza
Shapouri, et al. Electrophoretic Evaluation of Neisseris Meningitidis Serogroup A and B Outer
membrane Vesicle. The 3 rd Eurasia Congress of Infectious Diseases (EACID). Baku,
Azerbaijan .1-4 Oct. 2009. Poster Presentation.
39-Seyed Davar Siadat, Bahman Tabaraiee, M ohammad Reza Aghasadeghi, Ali Delbaz,
Dariush Norouzian, Jala Izadi Mobarakeh, Ali Sharifat, et all. Scale production of Neisseria
Meningitidis Class 1 Outer Membrane Vesicle .The 3 rd Eurasia Congress of Infectious Diseases
(EACID). Baku, Azerbaijan .1-4 Oct. 2009. Poster Presentation.
40-Seyed Davar Siadat, Daryoush Norouzian, M ohammad Reza Aghasadeghi, Jala Izadi
Mobarakeh .Brucellosis Vaccines: An Overview .3 rd Eurasia Congress of Infectious Diseases
(EACID). Baku, Azerbaijan .1-4 Oct. 2009. Poster Presentation.
41-Salem F, Aghasadeghi M R, Javadi F, Joolaee M, Bahramali G, Siadat SD, et all .Using
PCR- RFLP and Direct Sequwncing for determination of HBV genotype in intravenous drug
user prisoners in Tehran province .The 6 th Natinal Biotecnology Congress Of Iran .Milad Tower
Conference Hall, Tehran- Iran .13-15 Aug 2009. Poster Presentation
42-Monzavi Nastaran, Arabi Reza, Aghasadeghi M ohammad Reza, Mrmarnejadian Arash,
Sadat Seyed Mehdi, et all .Design, cloning, expression and evaluation of cysteine analogs of
truncated and intact molecules of streptokinase .The 6 th Natinal Biotecnology Congress Of Iran .
Milad Tower Conference Hall, Tehran- Iran .13-15 Aug 2009. Poster Presentation
43-Arabi Reza, Norouzian Daryoosh, Aghasadeghi M ohammad Reza, Khan Ahmad Hossein,
Memarnejadian arash,et all .Cloning and expression of truncated and intact molecules of
streptokinase in E.coli and enaluation of thei biological activities .The 6 th Natinal Biotecnology
Congress Of Iran .Milad Tower Conference Hall, Tehran- Iran .13-15 Aug 2009. Poster
Presentation.
44-Iranshahi N. Siadat SD, Tabraie B, Ranjbar R, Norouzian D, Harzandi MR, Aghasadeghi
M R, Sadat SM,et all. Evaluation of antibody susceptibility pattern in salmonella spp. Isolated
from ten provinces in Iran. 10th Iranian Congress of MICROBIOLOGY Illam- Iran. 21-23 April
2009 Poster Presentation
45-Aghasadeghi M .R, Sadat MSM, Khabiri A, Rouhvand F. Immunization of mice with HCV
core protein formulated in montained –ISA720 primes CD+8 CTLs and elicits Th1-Th2
Responses. 17th society of clinical microbiology and infectious diseases (ECCMID) 31 Mar-4
Apr2007. Munich- Germany Poster Presentation
46-Sadat S.M., Aghasadeghi M .R., Bahramali G., and Roohvand F. High expression of HCV
core protein: A comparative study on effect of 6xHis –tag location (N-versus C-terminal) and
purification method for various properties. 17th society of clinical microbiology and infectious
diseases (ECCMID) 31 Mar-4 Apr2007. Munich- Germany Poster Presentation